• Proceedings of the Korea Water Resources Association Conference
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• 2020.06a
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• pp.78-78
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• 2020

The Se San and Srepok river basins (2S) are the two major tributaries of the Mekong River, both of which originate in the territory of Viet Nam and flow to Cambodia to meet at Stung treng with the Sekong river (originating in Lao PDR) to form the 3S river basin before joining the Mekong mainstream. In the territory of Viet Nam, the 2S river basins are located in the Central Highlands including 5 provinces, arranged by geographical location from north to south namely Kon Tum, Gia Lai, Dak Lak, Dak Nong and Lam Dong. This is a region with a very important strategic position in terms of economy, politics and defense for the whole country with many potential advantages for economic development. However, the limited and vulnerable basin water resources are under the pressure of socio-economic development in line with increasing water demands for various sectors. In order to overcome the water management challenges, a long-term water resources planning has conducted to support the 2S River Basin Committee (RBC) in effective planning and operation as part of the WB Mekong-Integrated Water Resources Management (IWRM) Project. This paper introduces the outline and progress of the river basin planning using analytical DSS toolkits to analyze, evaluate and formulate the planning options.

• Journal of Ginseng Research
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• v.47 no.5
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• pp.627-637
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• 2023

Background: Damage to the healthy intestinal epithelial layer and regulation of the intestinal immune system, closely interrelated, are considered pivotal parts of the curative treatment for inflammatory bowel disease (IBD). Plant-based diets and phytochemicals can support the immune microenvironment in the intestinal epithelial barrier for a balanced immune system by improving the intestinal microecological balance and may have therapeutic potential in colitis. However, there have been only a few reports on the therapeutic potential of plant-derived exosome-like nanoparticles (PENs) and the underlying mechanism in colitis. This study aimed to assess the therapeutic effect of PENs from Panax ginseng, ginseng-derived exosome-like nanoparticles (GENs), in a mouse model of IBD, with a focus on the intestinal immune microenvironment. Method: To evaluate the anti-inflammatory effect of GENs on acute colitis, we treated GENs in Caco2 and lipopolysaccharide (LPS) -induced RAW 264.7 macrophages and analyzed the gene expression of proinflammatory cytokines and anti-inflammatory cytokines such as TNF-α, IL-6, and IL-10 by real-time PCR (RT-PCR). Furthermore, we further examined bacterial DNA from feces and determined the alteration of gut microbiota composition in DSS-induced colitis mice after administration of GENs through 16S rRNA gene sequencing analysis. Result: GENs with low toxicity showed a long-lasting intestinal retention effect for 48 h, which could lead to effective suppression of pro-inflammatory cytokines such as TNF-α and IL-6 production through inhibition of NF-κB in DSS-induced colitis. As a result, it showed longer colon length and suppressed thickening of the colon wall in the mice treated with GENs. Due to the amelioration of the progression of DSS-induced colitis with GENs treatment, the prolonged survival rate was observed for 17 days compared to 9 days in the PBS-treated group. In the gut microbiota analysis, the ratio of Firmicutes/Bacteroidota was decreased, which means GENs have therapeutic effectiveness against IBD. Ingesting GENs would be expected to slow colitis progression, strengthen the gut microbiota, and maintain gut homeostasis by preventing bacterial dysbiosis. Conclusion: GENs have a therapeutic effect on colitis through modulation of the intestinal microbiota and immune microenvironment. GENs not only ameliorate the inflammation in the damaged intestine by downregulating pro-inflammatory cytokines but also help balance the microbiota on the intestinal barrier and thereby improve the digestive system.

• Spatial Information Research
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• v.13 no.2 s.33
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• pp.139-155
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• 2005

Today, ever growing population density in Seoul or areas near Seoul is problematic. To overcome the problem, the government tries to construct so called, 'New-towns'near Seoul to spread out the population over larger areas. But building new-towns created another problem of traffic between Seoul and New-towns. It can be solved if more public transportation systems such as urban railroads are constructed. In order to succeed in urban railroad construction, we have to make a perfect plan through in depth research on characteristics of the urban train and the construction site. In this paper, we propose a method to design the Decision Support Systems(DSS) using Geographic Information Systems(GIS) and Spatial Analysis for the planning of urban railroad construction.

• Computers and Concrete
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• v.9 no.2
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• pp.99-118
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• 2012

Marine Structures are very costly and need a continuous inspection and maintenance routine. The most effective way to control the structural health is the application of an expert system that can evaluate the importance of any distress on the structure and provide a maintenance program. An extensive literature review, interviews with expert supervisors and a national survey are used to build a decision support system for concrete structures in sea environment. Decision trees are the main rules in this system. The system input is inspection information and the system output is the main cause(s) of distress(es) and the best repair method(s). Economic condition, severity of distress, distress situation, and new technologies and the most repeated classical methods are considered to choose the best repair method. A case study demonstrates the application of the developed decision support system for a type of marine structure.

• Proceedings of the Safety Management and Science Conference
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• 2000.11a
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• pp.101-104
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• 2000

본 연구는 우편물의 효율적인 수송을 위해 복합연계수송 개념을 도입한 Multi-commodity, Multi-modal Network Model과 이를 토대로 정식화하고 이를 적용 한 LHGO programming Model를 제안하고자 한다. 구축된 LINGO Model은 응용 Application내에 장착되어지는 Module로 구성가능하며 이를 GIS Tool인 GEOmania를 이용한 우편물 수송 DSS을 위한 Application 개발에 활용하고자 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2002.04a
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• pp.75-78
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• 2002

데이타베이스 공유 시스템(Database Sharing System: DSS)은 고성능의 온라인 트랜잭션 처리를 위해 다수 개의 컴퓨터를 연동하는 방식으로 각 노드들은 디스크 계층에서 데이타베이스를 공유한다. DSS를 구성하는 각 노드에 트랜잭션을 할당하는 정책이 잘못될 경우 특정 트랜잭션의 폭주로 노드에 과부하가 발생할 수 있으므로. 각 노드의 성능을 최적화하기 위한 부하 분산이 필요하다. 본 논문에서는 트랜잭션 클래스에서 참조하는 데이터베이스의 핫 셋 크기, 각 노드의 메모리 크기와 CPU 성능, 동시에 실행되는 트랜잭션 수의 변화에 따른 처리량 등을 고려한 동적 부하 분산 기법을 제안한다.

• IE interfaces
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• v.4 no.2
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• pp.53-66
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• 1991

For the strategic management of the small and/or mid sized clinics, the introduction of the clinic information system is necessary. Currently there are not many information systems for the clinics, yet. In this study, we have developed a clinic information system (CLINSYS) as a guiding prototype and suggested the development directions of the total integrated clinic decision support system. For the better user interface and easy communication. the object-oriented language Macintosh Hyper-Card and Excel are used as the developing tools. And as a part of the integrated decision system, an expert system to consult about the urine test and the blood test interpretation has been developed using the Macintosh spreadsheet Excel.

• Journal of Korean Society of Forest Science
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• v.101 no.2
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• pp.213-219
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• 2012

The $5^{th}$ national forest inventory (NFI5) has been reorganized to annual inventory system for providing multi-resources forest statistics at a point in time. The objective of this study is to evaluate statistical estimators for estimating forest growing stock in Chungcheongbuk-Do from annual inventory data. When comparing two estimators; simple random sampling (SRS) and double sampling for post-stratification (DSS), for estimating mean forest growing stock ($m^3/ha$) at each surveyed year, the estimate for DSS in which a population of interest is stratified into three sub-population (forest cover types) was more precise than that for SRS. To combine annual inventory field data, three estimators (Temporally Indifferent Method; TIM, Moving Average; MA, and Weighted Moving Average; WMA) were compared. Even though the estimated mean for TIM and WMA is identical, WMA-DSS is preferred to provide more smaller variance of estimated mean and to adjust for catastrophic events at a surveyed year (so-called "lag bias") by annual inventory data.

• Journal of Life Science
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• v.32 no.1
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• pp.36-43
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• 2022

Mucosal immunity is a well-designed defense system that builds precise and dynamic relationships against pathogens, and the gastrointestinal tract is the most important organ with this system, acting as a guardian at the forefront of its activity. Salmonella spp. cause food poisoning, entering the body orally and mainly invading the Peyer's patches of the small intestine. Although Salmonella strains share similar mechanisms for inducing innate immunity, different serotypes may have different effects on the intestinal mucosa due to host specificities and pathogenicity. In this study, we evaluated the effects of Salmonella enteritidis infections in mouse intestine and observed significantly reduced dose-dependent survival rates in a challenge test. Flow cytometry data showed no significant differences in intestinal immune cell populations, although histology indicated increased mucin production and decreased goblet cell counts in the Salmonella-treated groups. Furthermore, Claudin expression was significantly decreased in the samples with Salmonella. To investigate the relationship between S. enteritidis infection and inflammatory response, dextran sodium sulfate (DSS) was administered after infection and the results indicate lower survival rate after DSS treatment. In conclusion, we were able to identify the optimal concentration of S. enteritidis to modulate the intestinal mucosal immunity of mice and inflammatory response.

• The Journal of Korea Robotics Society
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• v.2 no.3
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• pp.242-248
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• 2007

Robot system development consists of several sub-tasks such as layout design, motion planing, and sensor programming etc. In general, on-line programming and debugging for such tasks demands burdensome time and labor costs, which motivates an off-line graphic simulation system. MSRS(Microsoft Robotics Studio) released in recent years is an appropriate tool for the graphic simulation system since it supports CCR(Concurrency and Coordination Runtime), DSS(Decentralized System Services), and dynamics simulation based on PhysX and graphic animation as well. In this paper, we developed an MSRS based network simulation system for quadruped walking robots, which controls virtual 3D graphic robots existing in remote side through internet.