• 한국산학기술학회논문지
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• 제17권5호
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• pp.660-670
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• 2016

본 연구는 혈액투석환자의 증상경험, 영적안녕 및 우울과의 관계를 확인하고 우울에 미치는 영향력을 파악하고자 시도된 서술적 조사연구이다. 연구 자료는 2014년 10월 15일부터 2015년 1월 15일까지 6개 투석기관으로부터 146명의 환자로 부터 수집되었다. 연구도구는 Dialysis Symptom Index, Spiritual Well-being Scale, and Center for Epidemiologic Studies Depression Scale이 사용되었다. 자료 분석은 ANOVA, t-test, Scheffe test, Pearson correlation 및 위계적 다중회귀 분석으로 이루어졌다. 연구결과 투석환자의 증상경험은 평균 26.43(범위:0~85), 영적안녕 평균 47.79(범위: 20~80), 우울 평균 10.56(범위: 0~35)로 나타났다. 실존적 영적안녕이 높을수록 우울정도가 낮고 (r=-.23, p=.004), 증상경험이 낮은 것으로 나타났다(r=-.17, p=.045). 혈액투석환자의 우울은 신체적 증상이 많고(B=.09), 정서적 증상이 클수록(B=.64) 우울 정도가 높은 것으로 나타났으며 모형의 설명력은 52.1%로 높았다(F=18.54, p<.001). 따라서 혈액투석환자의 우울을 완화시키기 위한 중재에는 증상을 경감시키고 실존적 영적안녕을 증진시키는 프로그램이 포함될 필요가 있겠다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2815-2819
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• 2014

Background: The aim of this study was to evaluate the prognosis of patients with stage IA-IIB cervical carcinoma and to investigate a possible correlation of histology with prognosis. Materials and Methods: Two hundred fifty one patients with adenocarcinoma and squamous cell carcinoma (SCC) histology for FIGO (International Federation of Gynecology and Obstetrics) stage IA-IIB uterine cervical carcinomas at the Radiation Oncology Clinic of GH Okmeydan Training and Research Hospital between January 1996 and December 2006 were selected, analyzed retrospectively and evaluated in terms of general characteristics and survival. Disease-free survival (DFS) and overall survival (OS) was calculated using the Kaplan-Meier method and differences were compared with the log-rank test. Multivariate analysis using a Cox-proportional hazards model was used to adjust for prognostic factors and to estimate hazard ratio (HR) with 95% confidence interval (CI). Results: There was no differences between the two tumour types in age, stage, pelvic nodal metastasis, parametrial invasion, surgical margin status, DSI, LVSI, maximal tumor diameter, grade, and treatment modalities. 5-year OS and DFS were 73% and 77%, versus 64% and 69%, for SCC and adenocarcinoma, respectively (p> 0.05). Multivariate analysis revealed independent prognostic factors including pelvic nodal metastasis and resection margin status for OS (p=0.008, p=0.002, respectively). Conclusions: Prognosis of FIGO stage IA-IIB cervical cancer patients was found to be the same for those with adenocarcinoma and SCC.