• Animal cells and systems
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• 제8권3호
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• pp.221-229
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• 2004

The projections from the dorsal raphe (DR) to the locus coeruleus (LC) or vice versa were analyzed in the rat using an anterograde tracer, Phaseolus vulgaris leucoagglutinin (PHA-L) combined with serotonin (5-hydroxytryptamine, 5-HT) or dopamine-beta-hydroxylase (DBH) immunostaining. Following the injection of PHA-L into the middle DR, DR-originating fibers with varicosities have contacted DBH-immunolabeled cells in the rostral, middle, and caudal LC. Axon terminals were also observed in the subcoeruleus nucleus. When the PHA-L injection was confined within the caudal DR, axonal fibers with varicosities were observed mainly at the rostral pole of the LC. Following the injection of PHA-L into the caudal, principal LC, labeled fibers with varicosities have contacted 5-HT-immunolabeled neurons at dorsomedial, ventromedial, lateral wing, and caudal sub-divisions of the DR. The present anterograde study suggests that the DR or the LC nuclei communicate with each other in order to perform a variety of functions including vigilance, analgesia, and stress responses.

• Journal of Power Electronics
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• 제13권2호
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• pp.250-255
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• 2013

This paper proposes an optimal current distribution method of dual-rotor brushless DC machines (DR-BLDCMs) which have inner and outer surface-mounted permanent-magnet rotors. The DR-BLDCM has high power density and high torque density compare to the conventional single rotor BLDCM. To drive the DR-BLDCM, dual 3-phase PWM inverters are required to excite the currents of a dual stator of the DR-BLDCM and an optimal current distribution algorithm is also needed to enhance the system efficiency. In this paper, the copper loss and the switching loss of a DR-BLDCM drive system are analyzed according to the motor parameters and the switching frequency. Moreover, the optimal current distribution method is proposed to minimize the total electrical loss. The validity of the proposed method was verified through several experiments.

• 제어로봇시스템학회논문지
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• 제2권3호
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• pp.188-193
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• 1996

In this paper, an integrated navigation system based on GPS(Global Positioning System) and Dead-Reckoning (DR) is designed. For the calibration of DR, a self-calibration method and a GPS-based calibration method are proposed. From the field-test results, it is shown that DR can be successfully calibrated by the two proposed calibration methods. Also, a cascaded filter approach and a mixed-measurement algorithm are employed for GPS/DR integration. By using the newly proposed mixed-measurement algorithm, it is shown in simulation that the position error becomes smaller than by using only DR even if the number of visible GPS satellites is less than 4.

• 한국식품영양과학회지
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• 제30권3호
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• pp.521-527
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• 2001

The effects of dietary restriction (DR) on antioxidant enzymes were studied in liver, lung and erythrocytes of diabetic rats. Experimental animals used Sprague-Dawley (SD; body weight 350$\pm$20g) male rats and Otsuka Long Evans Tokushima fatty (OLETE; body weight 5--$\pm$30g) male rats, as a model of type 2 diabetes mellitus. Type I diabetes was induced in SD rats by intramuscular injection of alloxan (80 mg/kg BW). Animals were randomly assigned either to continue the ad libitum diet or 40% DR (60% intake of ad libitum diet) groups. The body weight was measured at every 2 weeks to 4 months following DR. The activities of antioxidant enzymes (superoxide dismutase (SOD), catalase, glutathione peroxidase (GSHPx) were measured in liver, lung and erythrocytes and the concentration of TBARS as a marker of reactive oxygen species-induced tissue injry was also measured in rats after 4 months 40% DR. The body weight 4 months after 40% DR of control SD, alloxian-diabetid SD and OLETE rats were 80%, 98% and 75% of each control groups, respectively. The activities of SOD, catalase and GSHPx in lung and erythrocytes of rats were not change by 40% DR but in 4 month 40% DR rat liver, the activities of SOD and catalase were increased in control SD, alloxan-diabetic SD, and OLETF groups. The concentration of TBARS in lung and erythrocytes was also not changed by 40% DR, while liver TBARS concentration was decreased in OLETF and control SD rats compared to each non-DR control rats. These results suggested that the body weight changes in diabetic rats by DR was more prominent in type 2 diabetes and changes of antioxidant enzymes is most prominent in liver by DR either type 1 and 2 diabetic rats.

• Journal of Radiation Protection and Research
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• 제24권3호
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• pp.161-170
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• 1999

비정질 실리콘 방사선 촬영기와 기존 X-ray filmrh과의 영상질 비교를 통하여 시스템의 성능을 평가하였다. 다양한 영상질 평가를 위하여 MTF (Modulation Transfer Function), NPS (Noise Power Spectrum), Contrast를 측정하여 계산하였다. 실험 결과 DR의 MTF는 기존 film-screen system과 유사하였다. Noise 특성은 두 시스템 모두 quantum noise가 주를 이뤘으며, 특히 DR 에서는 전기적인 noise가 발견되었다. 또한 우수한 sensitivity 특성과 영상처리를 통하여 DR 시스템이 기존의 film-screen 시스템보다 놀은 대조도를 보였다. 이와 같이 DR에서는 기존 film-screen 시스템과 유사한 해상도와 영상처리를 통해 같은 촬영조건에서도 향상된 대조도의 영상을 얻을 수 있었다. 본 연구를 통하여 의학적 활용과 관련된DR 시스템의성능에 대한 유용한 정보를 제공할 수 있으리라 기대한다.

• Journal of Acupuncture Research
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• 제25권3호
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• pp.71-86
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• 2008

Objectives & Methods : The purpose of this study is to observe the effects of Drynariae Rhizoma Herbal-acupuncture infusion solution at Umgok($KI_{10}$) on Osteoporotic Rats Induced by Ovariectomy. The author performed several experimental items to analyze cytotoxic, osteoporosis evaluation, change of ALP, osteocalcin, Ca and histological change of tibia. Results : 1. BMD were increased meaningly in DR-HA than control group. 2. ALP was not inhibited by DR-HA, osteocalcin was decreased meaningly in DR-HA. 3. Osteoclast like cell in tibia was increased meaningly in control group, decreased meaningly in DR-HA. 4. In the histological study in tibia, TBV and TBT were significantly increased, GPL was significantly decreased in the DR-HA than control group. Conclusions : From the result above, the results suggest that DR-HA at $KI_{10}$ has significant effect on osteoporosis, and to be put to practical use in the future osteoporosis clinic.

• Journal of Electrical Engineering and Technology
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• 제10권3호
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• pp.755-765
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• 2015

A thermostatically controlled load (TCL) can be one of the most appropriate resources for demand response (DR) in a smart grid environment. DR capability can be effectively implemented in a TCL with various intelligent control methods. However, because traditional on-off control is still a commonly used method in a TCL, it is useful to develop a method for adding DR capability to the TCL with an existing on-off controller. As a specific realization of supervisory control for implementing DR capability in the TCL, two methods are proposed - a method involving the changing of a set point and a method involving the paralleling of an identified system without delay. The proposed methods are analyzed through the simulations with an electric heater for different power consumption levels in the on-state. Considerable cost benefit can be achieved with the proposed methods when compared with the case without DR. In addition, the observations suggest that a medium power consumption level, instead of the maximum power, in the on-state should be used for consistently obtaining the cost benefit without severe temperature deviation from the specified temperature range for DR.

• Current Photovoltaic Research
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• 제5권3호
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• pp.100-104
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• 2017

This paper analyzes the correlation between Net Benefit Test (NBT) and System marginal price (SMP), which has a significant impact on the allocation of demand response (DR) resources in resource scheduling and commitment (RSC) process, based on the performance data of the demand resource market which has been established in 2014. Demand resources compete with generation resources in the RSC process, and it is prescribed to use demand resources only when net benefit occurs. Analysis result shows that the larger the SMP than the Net Benefit Threshold Price (NBTP), the more the winning bid of demand response resource was. It is interpreted that the introduction of NBT in DR market is justified. The demand resource market has been steadily growing. It is required to expand the scope of resources up to the small-sized DR, and to expand the functionalities of demand resources not only in the current energy market but also in the reserve market in the future. In order for that, institutional improvements are required.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권3호
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• pp.159-165
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• 2019

Background: Dental procedures commonly involve the injection of local anesthetic agents, which causes apprehension in patients. The objective of dental practice is to provide painless treatment to the patient. The purpose of this study was to evaluate the effect of Low Level Laser Therapy (LLLT) in reducing the pain due to local anesthetic injection. Materials and Methods: A prospective, split-mouth study was conducted on 25 patients. In Condition A, LLLT was administered followed by the administration of a standard local anesthetic agent. Patients' perception of pain with use of LLLT was assessed based on a Visual Analogue Scale (VAS). In Condition B, LLLT was directed to the mucosa but not activated, followed by the administration of local anesthesia. VAS was used to assess the pain level without the use of LLLT. Results: Comparison between Condition A and Condition B was done. A P value < 0.001 was considered significant, indicating a definite statistical difference between the two conditions. Conclusion: In our study, we observed that LLLT reduced pain during injection of local anesthesia. Further multi-centric studies with a larger sample size and various modifications in the study design are required.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권3호
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• pp.135-141
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• 2019

Background: The fear of needle insertion and pain during anesthesia is a source of patient dissatisfaction in dentistry. Inferior alveolar nerve block (IANB) remains the most common type of block and is in itself painful. Computer-controlled local anesthetic delivery (CCLAD) has been proven to reduce the pain associated with injection of anesthetics in various blocks. However, the efficacy of CCLAD for IANB in adults remains unknown. Methods: Sixty-four adult patients requiring bilateral IANB were selected and divided into two groups: group A (50 patients receiving IANB via CCLAD) and group B (50 patients receiving IANB using a conventional cartridge syringe). Pain perception and patient comfort were assessed using the visual analog scale and the 5-point semantic scale, respectively. Results: The pain perception was compared between the two groups using the Mann-Whitney U-test, and the P value was 0.003. The patient comfort was also compared using the same test, and the P value was 0.484. Conclusion: A significant difference was observed in the pain perception of the patients during CCLAD. The patient comfort was grossly equal for both techniques.