• 제목/요약/키워드: DPA-714

검색결과 1건 처리시간 0.014초

A pyrazolopyrimidine-based radioligand for imaging of the translocator protein

  • Kwon, Young-Do;Kim, Hee-Kwon
    • 대한방사성의약품학회지
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    • 제2권2호
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    • pp.69-72
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    • 2016
  • Since the translocator protein (TSPO) is involved in neurodegeneration diseases, many scientists' interest has been focused on the development of a ligand targeting TSPO. A novel compound based on pyrazolo[1,5 -a] pyrimidine structure, DPA-714, has been studied and considered as a TSPO ligand with high affinity. In this highlight review, several researches for the novel radioligand for the translocator protein are illustrated.