• The Journal of the Society of Stroke on Korean Medicine
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• v.18 no.1
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• pp.67-75
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• 2017

■ Objective This is a case report about monocular abducens nerve palsy in a patient with pontine infarction. ■ Method At the time of onset, the patient had eye movement impairment in right eye and diplopia. Brain MRI image showed that there was an infarction in the right pons where the nucleus of abducens nerve is located. There was no obvious improvement in the eye movement before he received Korean medicine treatment. He recieved Korean medicine including acupuncture, electroacupuncture, pharmacoacupuncture and herb medicines for fifty three days. ■ Result After treatment, the movement of right eye was improved to a normal range. The difference in distance from 'center of the pupil' to 'external canthus of the eye' at maximum abducent in both eye changed 0.9cm to 0.1cm at the discharge. In addition, Diplopia was improved at the discharge. ■ Conclusion This case report demonstrated that the Korean medicine treatment is effective to diplopia and eye movement impairment from abducens nerve palsy caused by pontine infarction.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.2
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• pp.437-444
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• 2017

Stress concentrations around discontinuities, such as a hole in cross section of a structural member, have great importance because the most materials failure around the region may be occurred. Stress on the point applied by concentrated load reaches much larger value than the average stress in structural member. In this paper, stress analysis was performed for the plate with a partial through-hole to find the difference of the principal stress distribution. The difference between maximum principal stress and minimum principal stress in photoelasticity is equal to the value obtained by multiplying the isochromatic fringe order by the fringe constant of the material divided by the distance through which the light passes, that is, the thickness of the specimen. Since the difference of principal stress is proportional to the photoelastic fringe order, the distribution of the principal stress difference by the finite element analysis can be compared with the photoelasticity experimental result. ANSYS Workbench, that is the finite element software, is used to compute the differences of principal stresses at the specific points on the measured lines. The computation values obtained by ANSYS are compared with the experimental measurements by photoelasticity, and two results are comparable to each other. In addition, the stress concentration factor is obtained using the stress distribution analyzed from the variation of hole depth. Stress concentration factor is increasing, as the depth of hole increase.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.9
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• pp.141-149
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• 2017

Numerous products are on the market every day and consumption is becoming increasingly polarized. Some products have been introduced to the market for the first time and others are the existing products that have upgraded performance. For companies, new products must be released constantly to prevent losing existing customers and to increase loyalty. However, when companies released new product, they communicate consumer brand name and core benefits of the new product. Moreover, if a new product fails, the amount that the company has to pay is bound to grow. So companies often use brand extension strategies that use the names of famous brands that are already loved by their customers for new products. In this study, the effect of extension similarity, time of release, and message type on brand extension was investigated. Result shows that using abstract messages rather than specific messages is more effective when similarities with existing brands are poor. In particular, the closer the release period is, the more effective these effects are. However, in case of extending the brand with high similarity products, it is effective to focus on concrete messages when the release time is near, and to communicate abstract messages when the release time is long. This result suggests that companies should take into consideration not only the similarity of extension but also the timing and characteristics of messages when extending the brand.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.33 no.2
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• pp.115-125
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• 2023

Objectives: This study was conducted to measure the level of radon in the air at a highway tunnel construction site in a gneiss area using the New Austrian Tunneling Method (NATM) and to evaluate exposure levels by occupation. Methods: Radon concentrations in the air were measured using E-PERM at points 300 m, 600 m, and 900 m from the tunnel entrance during the excavation and waterproofing work inside the tunnel. In addition, radon concentrations were measured during external excavation to compare with the inside of the tunnel. Personal exposure levels for major occupations including tunnel workers, construction equipment operators, waterproofers, shotcrete workers, and safety and health managers who participated in the construction were estimated using radon concentration measured in the work process area and working hours by occupation. Results: As a result of a total of 77 radon measurements, the geometric mean (GM) concentration was 71.1 Bq/m³, and the maximum concentration was 127.3 Bq/m³, which was below the indoor air quality criteria. Radon concentration by process decreased in the order of the tunnel excavation process (GM= Bq/m³, GSD=1.2), waterproofing process (GM=73.35 Bq/m³, GSD=1.2), and outside excavating process (GM=45.28 Bq/m³, GSD=1.2). Processes inside the tunnel were significantly higher than outside excavating processes (p<0.05). There was no statistically significant difference in radon concentration measured inside by distance from the tunnel entrance, but the innermost point of the tunnel, 900 m (GM=79.24 Bq/m³, GSD=1.27), measured the highest. Conclusions: The occupation with the highest individual exposure to radon was tunnel worker (64.16 Bq/m³), followed by construction equipment driver (64.04 Bq/m³) and waterproofer (63.13 Bq/m³).

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.22 no.3
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• pp.1-19
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• 2023

Bikes have recently emerged as an alternative to carbon neutrality. To understand the demand for public bikes, we endeavored to estimate travel frequency of public bike by considering the intermediate stops. Using the GPS trajectory data of 'Ttareungyi', a public bike service in Seoul, we identified a stay point and estimated travel frequency reflecting population, land use, and physical characteristics. Application of map matching and a stay point detection algorithm revealed that stay point appeared in about 12.1% of the total trips. Compared to a trip without stay point, the trip with stay point has a longer average travel distance and travel time and a higher occurrence rate during off-peak hours. According to visualization analysis, the stay points are mainly found in parks, leisure facilities, and business facilities. To consider the stay point, the unit of analysis was set as a hexagonal grid rather than the existing rental station base. Travel frequency considering the stay point were analyzed using the Zero-Inflated Negative Binomial (ZINB) model. Results of our analysis revealed that the travel frequency were higher in bike infrastructure where the safety of bike users was secured, such as 'Bikepath' and 'Bike and pedestrian path'. Also, public bikes play a role as first & last mile means of access to public transportation. The measure of travel frequency was also observed to increase in life and employment centers. Considering the results of this analysis, securing safety facilities and space for users should be given priority when planning any additional expansion of bike infrastructure. Moreover, there is a necessity to establish a plan to supply bike infrastructure facilities linked to public transportation, especially the subway.

• BMB Reports
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• v.56 no.6
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• pp.359-364
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• 2023

KAI1/CD82, a membrane tetraspanin protein, can prevent various cancers and retinal disorders through its anti-angiogenic and anti-metastatic capacity. However, little is known about its anti-inflammatory effect and molecular mechanism. Therefore, the present study aimed to inLPSvestigate effect of a recombinant protein of the large extracellular domain of human KAI1 (Gly 111-Leu 228, rhKAI1) on lipopolysaccharides (LPS)-stimulated RAW264.7 macrophage-like cells and mouse bone marrow-derived macrophages (BMDM) and to identify its underlying mechanism. Our data showed that rhKAI1 suppressed expression levels of classically macrophages (M1) phenotype-related surface markers F4/80+CD86+ in LPS-stimulated BMDM and RAW264.7 cells. In addition, LPS markedly increased mRNA expression and release levels of pro-inflammatory cytokines and mediators such as interleukin (IL)-1β, IL-6, tumor necrosis factor-α, cyclooxygenase-2, nitric oxide and prostaglandin E2, whereas these increases were substantially down-regulated by rhKAI1. Furthermore, LPS strongly increased expression of NF-κB p65 in the nuclei and phosphorylation of ERK, JNK, and p38 MAPK. However, nuclear translocation of NF-κB p65 and phosphorylation of JNK were greatly reversed in the presence of rhKAI1. Especially, rhKAI1 markedly suppressed expression of toll-like receptor (TLR4) and prevented binding of LPS with TLR4 through molecular docking predict analysis. Importantly, Glu 214 of rhKAI1 residue strongly interacted with Lys 360 of TLR4 residue, with a binding distance of 2.9 Å. Taken together, these findings suggest that rhKAI1 has an anti-inflammatory effect on LPS-polarized macrophages by interacting with TLR4 and down-regulating the JNK/NF-κB signaling pathway.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.22 no.3
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• pp.160-174
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• 2023

LiDAR plays a key role in autonomous vehicles, and to improve its visibility, it is necessary to improve its performance and the detection objects. Accordingly, this study proposes a shape for traffic safety signs that is advantageous for self-driving vehicles to recognize. Improvement plans are also proposed using a shape-recognition algorithm based on point cloud data collected through LiDAR sensors. For the experiment, a DBSCAN-based road-sign recognition and classification algorithm, which is commonly used in point cloud research, was developed, and a 32ch LiDAR was used in an actual road environment to conduct recognition performance tests for 5 types of road signs. As a result of the study, it was possible to detect a smaller number of point clouds with a regular triangle or rectangular shape that has vertical asymmetry than a square or circle. The results showed a high classification accuracy of 83% or more. In addition, when the size of the square mark was enlarged by 1.5 times, it was possible to classify it as a square despite an increase in the measurement distance. These results are expected to be used to improve dedicated roads and traffic safety facilities for sensors in the future autonomous driving era and to develop new facilities.

• Journal of Marine Life Science
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• v.1 no.1
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• pp.8-17
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• 2016

The family Pristiophoridae belonging to the order Pristiophoriformes consists of about 8 species and 2 genera in the world. Among them, only one species (Pristiophorus japonicus) is distributed in northwestern Pacific. The family is characterized by having an elongated and flattened rostrum with laterally projecting a low of sharp teeth. In order to clarify variability of local populations of P. japonicus, we investigated 16 individuals collected from four locations (Korea, n=6; Miyagi, n=1; Kochi Pref., n=1; Okinawa, n=8) for morphological and molecular analyses. Morphological analysis showed that there may exist three morphotypes, of which A morphotype (Korea, Miyagi, Kochi Pref.) has a short snout (26.8% of TL), being most similar to syntypes of P. japonicus. On the other hand, B morphotype (Okinawa) has a long (31.7% of TL) and wider snout (snout width at nostrils 5.2 times pre-oral length) and, C morphotype (Okinawa) has a long (31.7% of TL) and narrower snout (6.3 times). Molecular analysis using mitochondrial DNA cytochrome b DNA sequences (386 base pairs) showed that the K2P distance between A and C morphotypes were 2.1~2.7%, but those within A morphotype were 0.0~0.5%. We identified A morphotype as P. japonicus, and designated B and C morphotypes as Pristiophorus sp. 1 and Pristiophorus sp. 2, respectively. Further studies are required to elucidate the taxonomic status of two morphotypes of the sawshark in Okinawa.

• Journal of Marine Life Science
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• v.1 no.1
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• pp.25-30
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• 2016

We investigated the possibility of a bio-monitoring system for detecting hypoxic water in coastal area using shell valve movements of Pacific oyster (Crassostrea gigas), which showed most aquaculture production in Korea, with Hall element sensor. In filtrating water to confirm shell valve movement (SVM) under normal condition, it showed spikes which mean a relatively fast closing condition after opened condition of average 5~12 mm, and then the SVM showed back to opening condition slower than closing speed SVM numbers during light period were similar to that of dark period (p<0.05). When dissolved oxygen (DO) concentration was reduced from 7 mg l^-1 to 3 mg l^-1, SVM numbers were increasing with decreasing of DO, and showed abnormality SVMs as compare with normal condition. Moreover, in the condition of 2 mg l^-1, Distance between light and left shell showed gradually decreased, and then we could not detected SVMs due to closed condition. Thus, if we quickly detect abnormal environmental variations as hypoxia water using bio-monitoring of SVM, it may be contribute to increased productivity by dramatically reducing damages in aquaculture.

• 한국체육학회지인문사회과학편
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• v.55 no.1
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• pp.457-467
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• 2016

Understanding professional baseball fans' expenditure is expected to provide fundamental marketing information that help increase each team's marketing profits and values and produce a better economic impact on its community. In this regard, this study employed a survey method with a total of 372 residents located in Changwon. A questionnaire included factors such as demographics, consumption patterns and perceived socio-psychic effect(PSE), all of which were derived from literature review. A binary logistic regression was modeled with a dichotomous dependent variable, expenditure(30,000 won more or less). The following were input in the model as the independent variables in order to see the relationships; gender, marriage, education, occupation, income, location, age, leisure type, distance, companion, transportation, interest, and PSE. The results of the logistic regression analysis are as follows. Overall, the model was statistically significant, χ²(21, N=372)=59.159, p=.000. Cox and Snell R² was reported as .147 and .200 respectively. So, the model accounted for between 14.7% and 20.0% of the variation in expenditure. Among the independent variables, income, location, companion, and PSE were found to be the significant factors to expenditure. For income, subjects with 2 million won less of income, compared to those with 4 million won more, were .38 times less likely to pay the money of 30,000 won more. For location, subjects in Masan, compared to those in Jinhae, were 3.49 times more likely to pay 30,000 won more. Subjects in Changwon, compared to those in Jinhae, were 3.05 times more likely to pay 30,000 won more. For companion, people visiting the stadium alone, compared to those with friends/colleague, were .36 times less likely to pay 30,000 won more. For PSE, the odds of 30,000 won more paid increased by 1.37 times with one-unit increase in PSE.