• Safety and Health at Work
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• 제6권1호
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• pp.62-70
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• 2015

Background: Animal skin provides an ideal medium for the propagation of microorganisms and it is used like raw material in the tannery and footware industry. The aim of this study was to evaluate and identify the microbial load in oropharyngeal mucosa of tannery employees. Methods: The health risk was estimated based on the identification of microorganisms found in the oropharyngeal mucosa samples. The study was conducted in a tanners group and a control group. Samples were taken from oropharyngeal mucosa and inoculated on plates with selective medium. In the samples, bacteria were identified by 16S ribosomal DNA analysis and the yeasts through a presumptive method. In addition, the sensitivity of these microorganisms to antibiotics/antifungals was evaluated. Results: The identified bacteria belonged to the families Enterobacteriaceae, Pseudomonadaceae, Neisseriaceae, Alcaligenaceae, Moraxellaceae, and Xanthomonadaceae, of which some species are considered as pathogenic or opportunistic microorganisms; these bacteria were not present in the control group. Forty-two percent of bacteria identified in the tanners group are correlated with respiratory diseases. Yeasts were also identified, including the following species: Candida glabrata, Candida tropicalis, Candida albicans, and Candida krusei. Regarding the sensitivity test of bacteria identified in the tanners group, 90% showed sensitivity to piperacillin/tazobactam, 87% showed sensitivity to ticarcillin/clavulanic acid, 74% showed sensitivity to ampicillin/sulbactam, and 58% showed sensitivity to amoxicillin/clavulanic acid. Conclusion: Several of the bacteria and yeast identified in the oropharyngeal mucosa of tanners have been correlated with infections in humans and have already been reported as airborne microorganisms in this working environment, representing a health risk for workers.

• 한국건설순환자원학회논문집
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• 제3권1호
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• pp.54-64
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• 2007

This study is a fundamental research in order to establish the design code of recycled aggregate concrete structure. The structural properties of recycled aggregate concrete such as flexure, shear, fatigue, compression, and bond development are experimentally investigated and confirmed. In this study, laboratory-scale reinforced concrete beam, column, and pull-out test specimens using recycled coarse aggregate are manufactured. Then, the structural performances of recycled aggregate concrete according to replacement ratios of recycled coarse aggregate are evaluated. Also, finite element analysis using commercial code DIANA is carried out to predict the test results and the analysis results are compared with test results in this study. Structural test results showed that the structural performances of recycled aggregate concrete specimens with 60% replacement ratio are reduced by approximately 15-20%. These results indicated that the replacement ratio of recycled coarse aggregate within 30% is a suitable to use for structural members. The results of finite element analysis showed that the specimens with 30% replacement ratio possessed similar or more excellent structural performance than normal concrete specimens. However, recycled aggregate concrete with 60% replacement ratio of recycled coarse aggregate must be carefully considered for structural applications due to significant decrease of the failure loads.

• 대한본초학회지
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• 제35권5호
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• pp.33-39
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• 2020

Objectives : Increasing evidence supports the biological and pharmacological activities of essential oils on the central nervous system such as pain, anxiety, attention, arousal, relaxation, sedation and learning and memory. The purpose of present work is to investigate the protective effect and molecular mechanism of cypress essential oil (CEO) against scopolamine (SCO)-induced cognitive impairments in C57BL/6 mice. Methods : A series of behavior tests such as Morris water maze, passive avoidance, and fear conditioning tests were conducted to monitor learning and memory functions. Immunoblotting and RT-PCR were also performed in the hippocampal tissue to determine the underlying mechanism of CEO. Results : SCO induced cognitive impairments as assessed by decreased step-through latency in passive avoidance test, relatively low freezing time in fear conditioning test, and increased time spent to find the hidden platform in Morris water maze test. Conversely, CEO inhalation significantly reversed the SCO-induced cognitive impairments in C57BL/6 mice comparable to control levels. To elucidate the molecular mechanisms of memory enhancing effect of CEO we have examined the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus. CEO effectively elevated the protein as well as mRNA expression of BDNF via activation of cAMP response element binding protein (CREB). Conclusions : Our findings suggest that CEO inhalation effectively restored the SCO-impaired cognitive functions in C56BL/6 mice. This learning and memory enhancing effect of CEO was partly mediated by up-regulation of BDNF via activation of CREB.

• 한국환경보건학회지
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• 제35권6호
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• pp.461-467
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• 2009

Exposure analysis is a critical component of determining the health impact of pollutants. Global positioning systems (GPS) could be useful in developing time-location information for use in exposure analysis. This study compares four low cost GPS receivers with data logging capability (Garmin 60, Garmin Forerunner 201, GeoStats GeoLogger and Skytrx minitracker MT4100) in terms of accuracy, precision, and ease of use. The accuracy of the devices was determined at two known National Geodetic Survey points. The coordinates logged by the devices were compared when the devices were carried while walking and driving. The Garmin 60 showed better accuracy and precision than the GeoLogger when they were placed at the geodetic points. The Forerunner and Skytrx did not record when they were kept stationary. When the subject wore the devices while walking, the location of the devices differed by about 8 m on average between any two device combinations involving the four devices. The distance between the coordinates logged by the devices decreased when the devices were carried with their antennas facing the sky. All the devices showed similar routes when they were used in a car. All the devices except the Forerunner had satisfactory signal reception when they were worn and when they were carried in the car. The GeoLogger is less comfortable for the subject because of specific wearing requirements. This evaluation found that the Garmin 60 and the Skytrx may be useful in personal exposure analysis studies to record time-location data.

• Coupled systems mechanics
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• 제9권2호
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• pp.163-182
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• 2020

Coupled thermo-mechanical analysis of reinforced concrete slab at elevated temperatures from a fire accounting for nonlinear thermal parameters is carried out. The main focus of the paper is put on a one-way continuous reinforced concrete slab exposed to fire from the single (bottom) side as the most typical working condition under fire loading. Although contemporary techniques alongside the fire protection measures are in constant development, in most cases it is not possible to avoid the material deterioration particularly nearby the exposed surface from a fire. Thereby the structural fire resistance of reinforced concrete slabs is mostly influenced by a relative distance between reinforcement and the exposed surface. A parametric study with variable concrete cover ranging from 15 mm to 35 mm is performed. As the first part of a one-way coupled thermo-mechanical analysis, transient nonlinear heat transfer analysis is performed by applying the net heat flux on the exposed surface. The solution of proposed heat analysis is obtained at certain time steps of interest by α-method using the explicit Euler time-integration scheme. Spatial discretization is done by the finite element method using a 1D 2-noded truss element with the temperature nodal values as unknowns. The obtained results in terms of temperature field inside the element are compared with available numerical and experimental results. A high level of agreement can be observed, implying the proposed model capable of describing the temperature field during a fire. Accompanying thermal analysis, mechanical analysis is performed in two ways. Firstly, using the guidelines given in Eurocode 2 - Part 1-2 resulting in the fire resistance rating for the aforementioned concrete cover values. The second way is a fully numerical coupled analysis carried out in general-purpose finite element software DIANA FEA. Both approaches indicate structural fire behavior similar to those observed in large-scale fire tests.

• International Journal of Advanced Culture Technology
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• 제8권2호
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• pp.116-128
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• 2020

In this study, we introduce a multi-modal mixed reality (MR) application for advertising the main touristic landmarks on Jeju Island, and evaluate its effectiveness based on the Technology Acceptance Model (TAM) with a focus on the user's involvement in Korean culture (K-Culture). Specifically, we deployed several stimuli to enable users to retrieve information, visualize a variety of heritage content such as text, images, videos, virtual artifacts, and immerse in a VR environment to experience the heritage locations. The results of the online survey with 436 participants showed that for consumers with low K-Culture involvement, Perceived Usefulness and Perceived Ease-of-Use did not affect their Intention to Visit the island. Still, it had a significant impact on their Intention to Use the application. On the other hand, for the group with high K-Culture involvement, Perceived Usefulness had no effect on the Intention to Use and Intention to Visit. However, Perceived Ease-of-Use had a significant impact on their Intention to Use the application and Intention to Visit Jeju Island. Therefore, when user involvement in K-Culture is high, convenience of use has played a significant role in sensory media usage and the intention to visit, regardless of the usefulness of the mixed reality content. In contrast, users with low K-Culture involvement primarily focused on the functional aspects of the application. These findings open the path for follow-up studies on K-Culture involvement and immersive media tourism marketing, which will benefit digital tourism marketing and Korea's tourism industry.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제6권1호
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• pp.1-8
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• 2017

다기준 의사결정 시 활용할 수 있는 스카이라인 질의는 다수의 선택지 중에서 사용자가 '선호하지 않을 만한'(uninteresting) 선택지를 제거함으로써 사용자가 검토해야 하는 선택지의 수를 대폭 감소시키기 때문에 대용량 데이터 분석 시 매우 유용하게 활용될 수 있다. 이러한 배경에서 대용량 데이터에 대한 스카이라인 질의를 분산 병렬 처리하는 기법이 각광을 받고 있으며, 특히 맵리듀스(MapReduce) 기반의 분산 병렬 처리 기법 연구가 활발히 진행되어 왔다. 맵리듀스 기반 알고리즘의 병렬성 제고를 위해서는 부하 불균등 문제 중복 계산 문제 과다한 네트워크 비용 발생 문제를 해소해야 한다. 본 논문에서는 부하 불균등 문제와 중복 계산 문제를 해소하면서도 데이터 샘플링 기반 프루닝을 통해 네트워크 비용 절감 시킬 수 있는 맵리듀스 기반 병렬 스카이라인 질의 처리 기법인 MR-SEAP(MapReduce sample Skyline object Equality Angular Partitioning)을 소개한다. 또한 다양한 관점에서의 실험 평가함으로써 제안 기법의 효용성을 다방면으로 검증했다.

• 한국구조물진단유지관리공학회 논문집
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• 제5권4호
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• pp.227-233
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• 2001

최근 비약적인 경제발전에 힘입어 장대교량, 항만, 댐, 도로, 원자력 발전소 등과 같은 대규모 기간구조물의 건설이 증가하고 있으며, 구조물은 대형화 혹은 고강도화되는 추세에 있다. 특히, 전술한 구조물을 매스콘크리트로 가설하게 되면 초기재령시에 수화열로 인한 균열이 발생할 가능성이 매우 높기 때문에 효율적인 매스콘크리트의 개발과 매스콘크리트 구조물의 설계기술 및 시공방법이 중요한 연구대상으로 등장하게 된다. 본 논문에서는 가로 52.6m, 세로 14.4m, 높이 8.5m의 기계기초 매스콘크리트의 시공에 적합한 온도관리기법을 다음과 같은 단계로 제안하고자 한다. 먼저 온도상승요인을 최소화하는 콘크리트의 배합비를 산정한다. 산정된 콘크리트의 열특성을 측정하기 위해 단열온도실험을 수행하여 각종 열특성상수와 단열온도 상승곡선식을 도출한다. 이와 같은 열특성치를 콘크리트 구조체에 적용하여 열응력해석을 수행한다. 이와 같은 열응력해석을 통하여 구조물의 분할타설높이에 따라 온도균열이 발생하지 않는 콘크리트 내외부의 온도차를 결정한다. 이때 열응력해석에 범용 유한요소 프로그램인 Diana을 사용한다. 콘크리트의 타설은 현장조건과 타설시점을 최대로 고려하고 양생방법으로 콘크리트 내외부의 온도차를 최소화하기 위해 이중단열효과가 있는 거푸집과 가열장비을 사용한다. 또한 콘크리트의 온도관리를 위하여 구조물 내외부에 온도게이지를 매립하고 30분마다 계측을 수행하면서 콘크리트 내외부 온도차가 허용 해석범위를 유지하도록 한다. 양생기간은 7-10일 정도를 유지한다. 전술한 온도관리기법을 통하여 완공후 수평정밀도가 기초의 허용침하량으로 환산하여 $1{\mu}m$ 인 고정밀도의 기계기초는 완벽하게 시공되었다. 따라서 매스콘크리트의 온도균열을 제어할 수 있는 시공방법으로 제안한다. 또한 매스콘크리트의 내외부 온도차를 단열온도실험과 온도해석으로부터 정한 값이내로 제어하고 충분한 양생관리를 병행하면 수화열에 의한 콘크리트의 온도균열을 최소화할 수 있을 것으로 기대한다.

• 한국의류학회지
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• 제37권8호
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• pp.1029-1043
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• 2013

The pearl is a highly valuable gem that has historically represented wealth and power. Pearl necklaces have developed intro various types and represent an essential status item for modern women. This study first examines the symbolic and various meanings of pearls. Second, this study examines wearing types and pearl necklace patterns based on historical figures and modern fashion icons famous for personal displays of pearls. This study examines and analyzes various specialty publications about jewels, history of costumes, fashion magazines, academic research data, and internet search results. The conclusion of this study is as follows. Pearls have various symbolic meanings that are unlike other gems. Pearls represent purity, innocence, marital fidelity, an intimate relationship with the moon, frozen tears of God, solitude, triumph over adversity, wisdom, and sensual attraction. The societies and people traditionally famous for pearls were the Roman Empire, Queen Cleopatra of Egypt, Queen Theodora of the Byzantine Empire, Queen Elizabeth I, Queen Marie Antoinette, Empress of Eugenie Napoleon III, and Queen Alexandra. They showed a special affection for pearl necklaces and various wearing patterns unique to the time. Their pearl necklaces became a historic and symbolic legacy. Reestablished through the costume jewelry of cultivated pearls designed by Coco Chanel in the $20^{th}$ century, the pearl necklace has showed a variety of fashion trends in addition to a traditional symbolism of wealth and power. Josephine Baker, Louise Brooks, Marilyn Monroe, Elizabeth Taylor, Jacqueline Kennedy, Queen Elizabeth II, Princess Diana, Michelle Obama and Sarah Jessica Parker have worn notable pearl necklaces and established an individual style that utilizes the adornment of fashionable and stylish pearl necklaces. They have worn pearl necklaces while applying various fashion trend motifs to symbolic pearl features of that have changed the perception of the pearl and themselves.

• Journal of Genetic Medicine
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• 제17권1호
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• pp.39-42
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• 2020

The Senior-Loken syndrome was first described in 1961 as an oculo-renal disease consisting of familial juvenile nephronophthisis and Leber congenital amaurosis. It is a rare autosomal recessive disorder with a prevalence of 1:1,000,000 caused by mutations in nine genes (NPHP 1-8 and NPHP 10). Ocular manifestations (e.g., photophobia, nystagmus, and extreme hyperopia) occur within the first few years of life while renal manifestations (e.g., formation of multiple cysts impairing kidney function and end-stage renal disease) appear in late childhood to adolescence. Here, we report a case of a Filipino male presenting with rotatory nystagmus and progressive deterioration of vision since childhood. He had congenital amaurosis and juvenile nephronophthisis that progressed to end stage renal disease by age 19. All laboratory and imaging findings were consistent with chronic kidney disease. Molecular genetic testing of ciliopathy-related genes was performed revealing a homozygous mutation in exon 11 of the IQCB1/NPHP5 gene, c.1090C>T (p.Arg364^⁎). This sequence change created a premature translational stop signal resulting in a truncated protein product, nephrocystin-5 and its consequent loss of function. His symptoms eventually improved with initiation dialysis. The prognosis of Senior-Loken syndrome remains dismal and a high index of suspicion, early diagnosis and timely intervention of renal complications are warranted.