• Advances in Traditional Medicine
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• 제7권5호
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• pp.549-555
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• 2008

Bupleuri radix (Umbelliferae), the dried root of Bupleurum Chinense DC, has been clinically used to mitigate pain sensation. The descending pain control system consists of three major components, and modulation of pain in the periaqueductal gray is the most extensively studied descending pain control system. However, the relation of Bupleuri radix on the descending pain control system has not been clarified. In the present study, modulation of the aqueous extract of Bupleuri radix on glycine-induced ion current in the acutely dissociated periaqueductal gray neurons was investigated by using nystatin-perforated patch-clamp technique under voltage-clamp condition. In the present results, the glycine-induced ion current was significantly suppressed by 0.1 mg/ml Bupleuri radix, while treatment with $10^{-5}\;M$ naltrexone, opioid receptor antagonist, alleviated Bupleuri radix-induced inhibition on glycine-induced ion current. The present study showed that the aqueous extract of Bupleuri radix may activate descending pain control system through inhibition on glycine-induced ion current in the periaqueductal gray neurons and this effect is mediated by opioid receptors.

• Journal of Chest Surgery
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• 제35권2호
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• pp.161-165
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• 2002

하행 괴사성 종격동염은 대부분 경부 부위의 농양으로 시작하여 종격동으로 파급되는 매우 치명적인 질환이며 저자에 따라 25∼40%의 사망률을 보고하고 있다. 빠른 진단과 적절한 수술적 치료가 중요하며 수술적 치료의 방법에는 아직 여러 가지 방법들이 보고되고 있지만 농양의 완전한 배농이 특히 중요하다고 보고하고 있다. 배농술은 경부 절개를 통한 배농과 함께 흉부 내의 종격동 배농술이 필요하며 종격동 배농술은 대부분 개흉술을 통하여 시행되어 왔으나 개흉술에 따른 합병증과 수술부위의 감염 등이 술후 이환율을 증가시키는 원인이 될 수 있다. 반면에 흥강경을 이용한 배농은 경부 배농술 및 흉부 배농술을 동시에 시행할 수 있으며 좋은 수술시야를 보여주고 술후 환자의 회복이 빨라 하행 괴사성 종격동염의 좋은 치료 방법이라 생각된다.

• Archives of Reconstructive Microsurgery
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• 제22권1호
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• pp.13-17
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• 2013

Purpose: Although a fasciocutaneous perforator artery as a vascular pedicle has previously been shown to be predominant in the anterolateral thigh (ALT) flap, recent studies have shown that a myocutaneous perforator artery is predominant. We have attempted to attain a clinical understanding of the vascular variations in the ALT flap. Materials and Methods: We confirmed the origin of a perforator artery in 11 cases of ALT flap. We then reviewed the variations of the descending branch of the lateral femoral circumflex artery, known as the major origin of the flap, and the overall variations associated with an ALT flap. Results: In a total of 11 cases, there were 18 perforator arteries of the ALT flaps. In addition, there were 9 fasciocutaneous perforator arteries and another 9 myocutaneous ones. However, depending on the origin, there was great variability in the perforator artery. That is, there were unique variants in the descending branches of the lateral femoral circumflex artery, the major origin of the perforator artery, in 3 of the total 11 cases. Conclusion: Our results showed that (1) a perforator artery accounts for the high proportion of fasciocutaneous ones, (2) a perforator artery might not originate from the descending branch of the lateral femoral circumflex artery and (3) there might be unique variants in the descending branch. If considering this, surgeons would successfully elevate an ALT flap.

• Archives of Plastic Surgery
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• 제37권6호
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• pp.769-774
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• 2010

Purpose: As the soft tissue defect around the knee is difficult to reconstruct, local flap or free flap is used. Distally based anterolateral thigh pedicled flap introduced by Zhang uses sufficient reverse flow supplied from the vascular network around the knee. We report successful reconstruction of defect around knee by this method. Methods: Four patients with skin & soft tissue defect around knee have been treated for reconstruction using the distally based anterolateral thigh pedicled flap. First, the doppler was used to check the perforator flap of the descending branch of the lateral circumflex femoral artery and to draw and dissect the perforator flap as much as needed. After the dissection, the proximal of the descending branch was clamped and checked for sufficient supply of blood flow from the reverse flow and then ligated. It was dissected along the descending branch and in order to prevent damage to the joined parts of the descending branch and the lateral superior geniculate artery, a more careful ligation was done starting from 10 cm superior to the knee. The defect was reconstructed after securing enough vascular pedicle to cover all the damaged parts. Results: Not all patients suffered from flap necrosis. In case of the patient with chronic osteomyelitis, slight venous congestion was observed right after the surgery but it disappeared the following day. All three patients had no occurences of additional complications. Conclusion: Distally based anterolateral thigh pedicled flap was enough to provide large flap for knee reconstruction. It had sufficient blood flow and vascular pedicle. It also had taken short operation time compared to the free flap operation. The distally based anterolateral thigh pedicled flap used by the authors is a very useful way of reconstructing the area around knee.

• 한국융합학회논문지
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• 제9권11호
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• pp.385-391
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• 2018

본 논문의 평발인 대상자가 하이힐을 신고 계단을 내려갈 때 하지의 근활성도 변화를 알아보고자 한다. 이 연구의 대상자는 30명의 여학생으로 구성되어 있다. NDT를 이용하여 평발군과 정상군을 구분하였으며 표전근전도를 사용해 측정하였다. MG와 LG근활성도와 안, 가쪽 근공동활성도는 평발군에서 낮게 나타났고 근활성도 비율은 평발군이 안쪽에서 더 높게 나타났다. 그러므로 하이힐을 신은 평발군은 정상군보다 무릎관절 정렬에 더 많은 손상을 가질 가능성이 더 높으므로 계단을 내려갈 때 더 많은 주의가 필요할 것이다.

• Journal of Biosystems Engineering
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• 제43권4호
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• pp.331-341
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• 2018

Purpose: This study was conducted to develop a linear Proportional-Integral-Derivative (PID) control algorithm for the ascending and descending system of a rice transplanter and to analyze its response characteristics. Methods: A hydraulic model using a single-acting actuator, proportional valve and a PID control algorithm were developed for the ascending and descending system. The PID coefficients are tuned using the Ziegler-Nichols (Z-N) method and the characteristics of unit step response are analyzed to select the PID coefficients at various pump speeds. Results: Results showed that the performance of the PID controller was superior in any condition. It was found that the highest settling time and maximum overshoot were less than 0.210 s and 5%, respectively at all pump speed. It was determined that the steady state errors were 0% in all the cases. The lowest overshoot and settling time were calculated to be nearly 2.56% and 0.205 s, respectively at the pump rated speed (2650 rpm). Conclusions: The results indicated that the developed PID control algorithm would be feasible for the ascending and descending system of a rice transplanter. Finally, it would be helpful to plant the seedlings uniformly and improve the performance of the rice transplanter.

• 한국임상수의학회지
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• 제39권5호
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• pp.258-263
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• 2022

An eight-year-old, intact female, Shih-Tzu, weighing 4.5 kg presented with complaints of anorexia, pale mucous membrane, and vomiting for the past 5 days. On physical examination, nausea, abdominal pain, and melena were noted. On hematologic examination, severe anemia and thrombocytosis were identified. On radiographs examination, soft tissue opacity with small faint mineral opacity mass in the mid-abdomen and two mineral opacity regions in the cranial aspect of mass were identified. Ultrasonographic findings showed thickening of descending duodenal wall with loss of layering and mineralization within the duodenal wall and mesentery adjacent to the duodenal lesion. Computerized tomography showed circumferential wall thickening of descending duodenum with mineralization. Mineralization of the mesentery and mesenteric lymph nodes was identified. Based on the diagnostic imaging, the tentative diagnosis was descending duodenal tumor with dystrophic mineralization. Endoscopy revealed mucosal hemorrhage and erythema within the descending duodenum and stomach. Surgery was performed, and mineralization in the pancreatic tail to duodenum and mesentery was found. Resection of the duodenum, regional lymph node, and mineralized pancreatic region and the duodenal anastomosis were performed. The histologic examination revealed a high-grade undifferentiated duodenal carcinoma with metastases to the regional lymph node and mesentery. The patient was managed with supportive therapy for 8 days and discharged. The patient was followed up for 5 months and there were no complications.

• Journal of Chest Surgery
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• 제41권3호
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• pp.373-376
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• 2008

외상성 흉부 대동맥 파열에 의한 가성대동맥류에 대한 일반적인 치료 방법은 수술이다. 그러나 환자의 전신상태가 개흉술을 통한 수술 또는 체외순환보조를 통한 수술을 시행 받기 어려운 경우에는 다른 치료 방법을 선택해야 한다. 저자들은 두부, 복부, 골반의 광범위한 다발성 손상이 동반되어 수술적 치료를 시행하기 어려웠던 대동맥파열에 의한 가성대동맥류 환자에 대하여 중재적 시술을 통해 스텐트-그라프트를 삽입하여 치료한 1예를 문헌 고찰과 함께 보고하는 바이다.

• 대한본초학회지
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• 제23권2호
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• pp.203-212
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• 2008

Objectives : This study was performed to prove the anti-hypertensive and anti-diabetic effect of Mori Ramulus(MR). Methods : The examination was done on the femoral artery occlusion of the rat, and check the blood pressure. In addition, we observed therapueutic effects on diabetes rats induced by streptozotocin. Results : MR MeOH Ex, showed few effect on descending blood pressure in SD rat model. MR CHC13 layer (MRC) showed significant effect on descending blood pressure. MR was effective on the streptozotocin-induced diabetes SD rats. Especially MRC reduced the amount of serum glucose, BUN, triglyceride and insulin level. Conclusions : MRC could induce descending blood pressure in the rat model. Also, it is expected to be effective in diabetes treatment.

• Journal of Chest Surgery
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• 제20권3호
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• pp.588-592
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• 1987

A successful repair of traumatic descending thoracic aorta rupture was performed in a 27 year old man. The patient had automobile accident and transferred to our hospital. On admission, a chest film showed mediastinal widening and soon aortography was done. There was a fusiform aneurysm on the descending thoracic aorta just distal to the origin of the left subclavian artery measuring 5cm in diameter and 7cm in length. He underwent thoracotomy and the injured part of the aorta was replaced with a 24mm tightly Woven Dacron graft using femora-femoral bypass. The postoperative course was uneventful.