• 한국지능시스템학회논문지
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• 제7권2호
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• pp.25-33
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• 1997

A DEDS is a system whose states change in response to the occurence of events from a predefined event set. In this paper, we consider the optimal control and reasoning problem for Discrete Event Systems(DES) in the Temporal Logic Framework(TEL) which have been recnetly defined. The TLE is enhanced with objective functions(event cost indices) and a measurement space is alos deined. A sequence of event which drive the system form a give initial state to a given final state is generated by minimizing a cost functioin index. Our research goal is the reasoning of optimal trajectory and the design of the optimal controller for DESs. This procedure could be guided by the heuristic search methods. For the heuristic search, we suggested the Stochastic Ruler algorithm, instead of the A algorithm with difficulties as following ; the uniqueness of solutions, the computational complexity and how to select a heuristic function. This SR algorithm is used for solving the optimal problem. An example is shown to illustrate our results.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1997년도 추계학술대회 논문집 학회본부
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• pp.109-112
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• 1997

A Discrete Event Dynamic System is a system whose states change in response to the occurrence of events from a predefined event set. A major difficulty in developing analytical results for the systems is the lack of appropriate modeling techniques. This paper proposes the use of Real-time Temporal Logic as a modeling tool for the modeling and control of fixed-time traffic control problem which by way of a DEDS. The Real-time Temporal Logic Frameworks is extended with a suitable structure of modeling hard real-time constraints. Modeling rules are developed for several specific situations. It is shown how the graphical model can be translated to a system of linear equations and constraints.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1997년도 하계학술대회 논문집 B
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• pp.590-592
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• 1997

A Discrete Event Dynamic System is a system whose states change in response to the occurrence of events from a predefined event set. A major difficulty in developing analytical results for the systems is the lack of appropriate modeling techniques. This paper proposes the use of Real-time Temporal Logic as a modeling tool for the analysis and control of DEDS. The Real-time Temporal Logic Frameworks is extended with a suitable structure of modeling hard real-time constraints. Modeling rules are developed for several specific situations. It is shown how the graphical model can be translated to a system of linear equations and constraints.

• 한국시뮬레이션학회:학술대회논문집
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• 한국시뮬레이션학회 2001년도 The Seoul International Simulation Conference
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• pp.425-434
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• 2001

In this paper we introduce a general framework for the modeling, analysis and costing of logistic networks including supply chains (SCs). The employed modeling notation, the so-called Process Chain paradigm, is specifically developed for the application field of logistic networks which includes SCs. We view SCs as discrete event dynamic systems (DEDS) and apply corresponding simulative techniques in order to derive performance measures of the Process Chain model under investigation. For this purpose Process Chain models are automatically transformed into the input language of the simulation tool HIT. Subsequently, a cost accounting model using the performance measures is applied to obtain costs which are actually subject of interest. The usefulness and applicability of the approach is illustrated by a typical supply chain example. We investigate the impact of an additional SC channel between a manufacturer and web-consumers on the overall supply chain costs.

• BMB Reports
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• 제47권9호
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• pp.488-493
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• 2014

Adaptor protein FADD forms the death inducing signaling complex (DISC) by recruiting the initiating caspases-8 and -10 through homotypic death effector domain (DED) interactions. Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of death ligand-induced apoptosis downstream of death receptors, and FADD competes with procaspase-8/10 for recruitment for DISC. However, the mechanism of action of FADD and c-FLIP proteins remain poorly understood at the molecular level. In this study, we provide evidence indicating that the death effector domain (DED) of FADD interacts directly with the death effector domain of human c-FLIP. In addition, we use homology modeling to develop a molecular docking model of FADD and c-FLIP proteins. We also find that four structure-based mutants (E80A, L84A, K169A and Y171A) of c-FLIP DEDs disturb the interaction with FADD DED, and that these mutations lower the stability of the c-FLIP DED.