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Spectrum of Cytological Findings in Fine Needle Aspiration Cytology of Breast Lumps with Histopathology Correlation: Experience in a Tertiary Care Rural Hospital in India

  • Kochhar, Ajay Kumar;Jindal, Umesh;Singh, Karandeep
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7257-7260
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    • 2013
  • To determine the pattern of disease in patients presenting with breast lumps and to determine the sensitivity and specificity of fine needle aspiration cytology of benign and malignant diseases as a diagnostic tool by correlating with histopathology findings. This retrospective study was carried out in the Department of Pathology, Maharaja Agrasen Medical College, Agroha, from Jan 2008 to April 2012. Fine needle aspiration cytology was performed on 370 cases and out of these 52 cases were received in the Department for histopathological examination. Fibroadenoma was the most common disease encountered, in 88 (24%), with a peak incidence in second and third decade of life. Fibrocystic disease was second, being common in the third and fourth decades of life. Peak incidences of duct ectasia, granulomatous and tubercular mastitis were seen in the third decade. Gynaecomastia showed two peak incidences in second and sixth decades of life. Out of total 370 cases undergoing fine needle aspiration, benign cases were 316 (85.4%), malignant and suspicious were 54 (14.6%) and 10 (2.70%) respectively. Out of total 22 histological confirmed malignant lesions 19 were interpreted as malignant cytologically while two as suspicious and one as benign. All thirty histologically confirmed benign cases were diagnosed as benign cytologically. The sensitivity, specificity, positive and negative predictive values were 98%, 100%, 100% and 96.4% respectively. FNA cytology is highly accurate for diagnosis of breast masses. However, the clinician should correlate FNA cytological results with physical examination and imaging findings to prevent false negative and false positive events and to obtain optimal management of their patients.

MODELING LONG-TERM PAH ATTENUATION IN ESTUARINE SEDIMENT, CASE STUDY: ELIZABETH RIVER, VA

  • WANG P.F;CHOI WOO-HEE;LEATHER JIM;KIRTAY VIKKI
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.09b
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    • pp.1189-1192
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    • 2005
  • Due to their slow degradation properties, hydrophobic organic contaminants in estuarine sediment have been a concern for risks to human health and aquatic organisms. Studies of fate and transport of these contaminants in estuaries are further complicated by the fact that hydrodynamics and sediment transport processes in these regions are complex, involving processes with various temporal and spatial scales. In order to simulate and quantify long-term attenuation of Polycyclic Aromatic Hydrocarbons (PAH) in the Elizabeth River, VA, we develop a modeling approach, which employs the U.S. Environmental Protection Agency's water quality model, WASP, and encompasses key physical and chemical processes that govern long-term fate and transport of PAHs in the river. In this box-model configuration, freshwater inflows mix with ocean saline water and tidally averaged dispersion coefficients are obtained by calibration using measured salinity data. Sediment core field data is used to estimate the net deposition/erosion rate, treating only either the gross resuspension or deposition rate as the calibration parameter. Once calibrated, the model simulates fate and transport PAHs following the loading input to the river in 1967, nearly 4 decades ago. Sediment PAH concentrations are simulated over 1967-2022 and model results for Year 2002 are compared with field data measured at various locations of the river during that year. Sediment concentrations for Year 2012 and 2022 are also projected for various remedial actions. Since all the model parameters are based on empirical field data, model predictions should reflect responses based on the assumptions that have been governing the fate and sediment transport for the past decades.

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Rhabdomyosarcoma - an Epidemiological and Histopathologic Study of 277 Cases from a Major Tertiary Care Center in Karachi, Pakistan

  • Ahmad, Zubair;Din, Nasir Ud;Ahmad, Arsalan;Imran, Sheharbano;Pervez, Shahid;Ahmed, Rashida;Kayani, Naila
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.757-760
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    • 2015
  • Aim: To present the epidemiologic data (age, gender, size etc) and histopathologic and immunohistochemical features of cases of rhabdomyosarcoma (RMS) reported in our department. Settings: Section of Histopathology, Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi, Pakistan. Duration: All cases of RMS diagnosed between January 1, 2003 and December 31, 2012 were included in the study. Results: A total of 277 cases were included. Embryonal rhabdomyosarcoma (ERMS) was by far the dominant histologic type (87.4%) followed by alveolar type (ARMS)(9.4%). ERMS was much more common in males (64.0%)and over 65% of cases occurred in the first decade of life (over 90% in the first two decades). Head and neck region was commonest site for ERMS (46.7%), followed by the genitourinary system (16.1%). Over 65% cases of ARMS occurred in the extremities. Over 80% cases of ARMS occurred in the first 3 decades of life. Immunohistochemical staining for Desmin and MyoD1 was positive in 96.7% and 85.4% respectively. Conclusions: The epidemiologic data and microscopic findings in our patients are similar to international published data on rhabdomyosarcoma.

Pyogenic Granuloma: A Retrospective Analysis of Cases Treated Over a 10-Year

  • Koo, Mun Geun;Lee, Soo Hyang;Han, So Eun
    • Archives of Craniofacial Surgery
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    • v.18 no.1
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    • pp.16-20
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    • 2017
  • Background: Pyogenic granuloma (PG) is a benign vascular lesion of the mucosa and skin. Recent studies of the epidemiology of PG are rare. We aimed to retrospectively analyze characteristics of PG cases in South Korea. Methods: We reviewed the medical records of 155 patients treated for PG between March 2005 and May 2014. The male-to-female ratio was 1:1.2 (70 males, 85 females). The mean age of patients was 35.3 years. Results: A high occurrence was observed in the first and third decades in males, and the fourth to fifth decades in females. There was a statistically significant difference between genders according to age group (p<0.05). The average lesion diameter was $0.84{\pm}0.46cm$ (long axis). The most frequently involved site was the face (n=47). Bleeding was the primary complication (n=41). PG was mostly treated with excisional biopsy (n=74). The recurrence rate was 7.7% (n=12). Conclusion: We concluded that most common site of PG was the face, the age of female with PG is higher than previous studies, and finger is associated with trauma more than other sites. The most recent epidemiological information on PG of this study will support the treatment and diagnosis of PG and future research objectives.

Strategies for Conservation and Restoration of Freshwater Fish Species in Korea (한국 담수어류의 보존 및 복원 전략)

  • Kang, Eon-Jong;Bang, In-Chul;Yang, Hyun
    • Korean Journal of Ichthyology
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    • v.21 no.sup1
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    • pp.29-37
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    • 2009
  • The tiny fragment of freshwater body is providing home for huge biodiversity and resources for the existence of human. The competing demand for freshwater have been increased rapidly and it caused the declination of biodiversity in recent decades. Unlike the natural process of extinction in gradual progress, the current species extinction is accelerated by human activity. As a result many fish species are already extinct or alive only in captivity in the world and about fifty eight animal species are in endangered in Korea including eighteen freshwater species. Conservation of biodiversity is the process by which the prevention of loss or damage is attained, and is often associated with management of the natural environment. The practical action is classified into in-situ, or ex-situ depending on the location of the conservation effort. Recovery means the process by which the status of endangerment is improved to persist in the wild by re-introduction of species from ex-situ conservation population into nature or translocation of some population. However there are a lot of restrictions to complete it and successful results are known very rare in case. In this article the authors explore some strategies for conservation and restoration of freshwater fish species conducted in Korea for few years. The major causes are discussed in relation with the decline of freshwater fish diversity during few decades and some strategies are evaluated to advance the process of conservation. A study on the Korean bullhead, Pseudobagrus brevicorpus, is introduced as a case for ex-situ conservation and restoration in freshwater ecosystem.

The Transformation of Family Ethics in Korea (한국가족윤리 변천에 관한 연구)

  • Lee, Chung-Duk;Kim, Soon-Ok;Park, Huh-Sik;Kim, Kyeong-Shin
    • Journal of the Korean Home Economics Association
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    • v.37 no.6
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    • pp.23-40
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    • 1999
  • The aim of this study was to analysis the transformation of family ethics as appeared in Korean history. The contents of this study consist of two parts: literature reviews on the specific features of family ethics with lived history from the period of the Three States to 1950 decades and a survey research on family ethics and its transition after 1950 decades. For the latter, Questionnaires were distributed to the different each generations, from which 1194 data were obtained. The results can be summarized as follows: The transition of thought such as Buddhism, Confucianism and the change of economics condition are found to have impact on the family ethics in Korea. In contemporary history, The Korean War(6 ${\cdot}$ 25) had great influent on the change of the family ethics. Recently the conflict among the family members and family problems are influenced by the valiables such as generation and sex, especially with the changes of consciousness of feministic perspective. More over, while only miner change had appeared in Family Ethics during the society still remained in Eastern Value orientations before Cho-seon dynasty, the transformation Family Ethics seems to be the greatest with the cultural shock by the introduction of the Western Values depending on the religions and locality. Nevertheless, family-Centered orientations and confucianism(Hyo) have continued to remains as relatively important values.

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Esophageal Cancer in Brunei Darussalam over a three Decade Period: an Epidemiologic Study of Trends and Differences between Genders and Racial Groups

  • Chong, Vui Heng;Telisinghe, Pemasari Upali;Chong, Chee Fui
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.4123-4126
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    • 2015
  • Background: Carcinoma of the esophagus is associated with significant morbidity and mortality. The most common subtype is squamous cell carcinoma (SCC). In the past three decades, the incidence of SCC has been reported to be decreasing whereas esophageal adenocarcinoma (AC) is increasing. This study assessed the trend of esophageal cancer in Brunei Darussalam over a three decades period. Materials and Methods: The National Cancer registry was searched for esophageal cancers from 1986 to 2012. Data on age, gender, racial groups (Malays, Chinese, Indigenous and foreign nationals) and histology type were collected. The rate (ASR) and Age Specific Incidence rate (ASIR) were calculated. Results: The predominant tumor type was SCC which accounted for 89% of all esophageal cancer. The gender ratio was 2.25: 1 (male: female) and the mean age at diagnosis was $66.9{\pm}12.9$ years, significantly younger for esophageal AC ($57.2{\pm}16.0$) compared to SCC ($68.1{\pm}12.0$, p<0.05), and among the foreign nationals (p<0.05 for trend). The proportions of SCC among all esophageal cancers in the various racial groups were: Malays (87.8%), Chinese (100%), Indigenous (100%) and foreign nationals (20%). None of the Chinese and Indigenous groups were diagnosed with esophageal AC. The overall ASR for esophageal cancer was 2.1/100,000; 2.0/100,000 for SCC with a declining trend and 0.17/100,000 for esophageal AC, without any trend observed. Among the two major racial groups; the Chinese has higher ASR (3.42/100,000) compared to the Malays (ASR 0.95/100,000). Conclusions: SCC is the predominant tumor type of esophageal cancer in Brunei Darussalam and more common among the Chinese. There was a declining trend in the incidence of SCC but not for esophageal AC.

Revisit of Thermoplastic EPDM/PP Dynamic Vulcanizates

  • Lim, Jaehwa;Park, Jun Il;Park, Joon Chul;Jo, Mi Young;Bae, Jae Yeong;Choi, Seok Jin;Kim, Il
    • Elastomers and Composites
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    • v.52 no.1
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    • pp.35-47
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    • 2017
  • A comprehensive survey of the available literature showed that in the last few decades, there has been a growing interest in the use of thermoplastic vulcanizates (TPVs). TPVs are the second largest group of soft thermoplastic elastomers (TPEs) after styrene-based block copolymers, and offer a wide range of potential and proven applications, including in mechanical rubber goods, under-the-hood applications in the automotive field, industrial hose applications, electrical applications, consumer goods, and soft touch applications. Over the last two decades, TPVs have shown a strong and steady market growth (~12% per year). Commercialized TPVs are commonly based on blends of ethylene propylene diene monomer (EPDM) rubber and polypropylene (PP), and to a lesser extent on combinations of butyl or nitrile rubber with PP. EPDM/PP TPVs are characterized by finely dispersed crosslinked EPDM rubber particles (particles size varying between 0.5 and $2.0{\mu}m$) distributed in a continuous thermoplastic PP matrix. If the rubber particles of such a blend are small enough and if they are vulcanized well enough, then the properties of the blend are generally improved. This review article introduces various topics and aspects relevant to EPDM/PP TPVs. The development of TPVs, the use of various types of crosslinking systems and co-agents as crosslinking agents for PP/EPDM blends, the morphology and rheology of TPVs, and their typical end-use applications are also reviewed.

Normal Glenoid Size of the Korean in 7th and 8th Decades (한국인 60~70대의 정상 견갑골 관절와의 크기)

  • Moon, Young-Lae;Ha, Sang-Ho;Noh, Kyung-Hwan
    • Clinics in Shoulder and Elbow
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    • v.11 no.1
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    • pp.37-40
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    • 2008
  • Purpose: We wanted to evaluate the normal glenoid size of Koreans in their 7th and 8th decades by conducting Computed tomographic (CT) studies. Materials and Methods: The CT images were obtained from the normal scapulae of the patients (mean age: 68.8) who had humeral fracture. A display workstation version 2.0.73.315 was used to measure the scans to determine the maximal superoinferior (SI) and anteroposterior (AP) diameters of the glenoid vault. Results: The average diameters of curvature of the glenoid were 31.2 mm (range: 27 to 34 mm) in the superior-inferior direction and 26.1mm (range: 22 to 31mm) in the anterior-posterior direction. Conclusion: This study showed the normal glenoid size of Koreans and it is different from the size that the international literature reported. It should be an important factor for the treatment of fracture or in designing arthroplasty implants.

Long-term Trends in Pelagic Environments of the East Sea Ecosystem

  • Lee, Chung-Il;Lee, Jae-Young;Choi, Kwang-Ho;Park, Sung-Eun
    • Ocean Science Journal
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    • v.43 no.1
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    • pp.1-7
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    • 2008
  • Physical and biological environmental variations in the East Sea were investigated by analysing time-series of oceanographic data and meteorological indices. From 1971 to 2000, dominant periodicity in water temperature variations had two apparent periods of 3 to 4 years and of decades, especially in the southwestern part of the East Sea affected by the influence of inflowing Tsushima warm current. Fluctuating water temperature within a certain period appears to respond to El $Ni{\tilde{n}}o$ events with a time lag. It was found that there was a strong correlation between water temperature and El $Ni{\tilde{n}}o$ events with a time lag of 1.5 and 5.5 years for periods of 3 to 6 years and of decades, respectively. Corresponding with El $Ni{\tilde{n}}o$ events, water temperature variability also showed strong correlation with shift and/or changes in biological and chemical environments of nutrient concentrations, zooplankton biomass, and fisheries. However, there also occurred a short-term periodicity of water temperature variations. Within a period of 1 to 4 years, a relatively short-term cycle of water temperature variation had strong correlation with other climate indices such as Pacific Decadal Oscillation and monsoon index. After comparing coherence and phase spectrum between water temperature and different climate indices, we found that there was a shift of coherent periods to another climate index during the years when climate regime shift was reported.