• Journal of the Korean Society of Radiology
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• v.2 no.4
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• pp.5-9
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• 2008

Antiscatter grids are widely used in radiography to remove scattered X-rays and thus improve the image contrast. However, the use of grids makes moir$\acute{e}$ artifact in the digital image, and this can be a critical reason for a mistaken diagnosis. In this paper, we examined that moire artifacts are how to relate with grid frequency, pixel pitch and grid rotation angle. To experiment we prepared 6 grids having different line frequencies (4.0 to 8.5lines/mm) and tested with a DR imager having a $139{\mu}m{\times}139{\mu}m$ pixel size. In the result of this experiment, we could get data about moir$\acute{e}$ artifact that could be make solution to remove the line artifact for the successful use of the grid in digital radiography. The acquired data and theory through this experiment, are expected to make contribution to the elimination of moir$\acute{e}$ artifact in the DR system.

• Journal of Life Science
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• v.20 no.7
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• pp.1054-1065
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• 2010

SH21B is a natural composition composed of seven herbs: Scutellaria baicalensis Georgi, Prunus armeniaca Maxim, Ephedra sinica Stapf, Acorus gramineus Soland, Typha orientalis Presl, Polygala tenuifolia Willd and Nelumbo nucifera Gaertner (Ratio 3:3:3:3:3:2:2). In our previous study, we reported that SH21B inhibited adipogenesis and fat accumulation in 3T3-L1 cells through modulation of various regulators in the adipogenesis pathway. The aim of this study was to analyze the transcriptome profiles for the anti-adipogenic effects of SH21B in 3T3-L1 cells. Total RNAs from SH21B-treated 3T3-L1 cells were reverse-transcribed into cDNAs and hybridized to Affymetrix Mouse Gene 1.0 ST array. From microarray analyses, we identified 2,568 genes of which expressions were changed more than two-fold by SH21B, and the clustering analyses of these genes resulted in 9 clusters. Three clusters among the 9 showed down-regulation by SH21B (cluster 4, cluster 6 and cluster 9), and two clusters showed up-regulation by SH21B (cluster 7 and cluster 8) during the adipogenesis of 3T3-L1 cells. It was found that many genes related to cell proliferation and adipogenesis were included in these clusters. Clusters 4, 6 and 9 included genes which were related with adipogenesis induction and cell cycle arrest. Clusters 7 and 8 included genes related to cell proliferation as well as adipogenesis inhibition. These results suggest that the mechanisms of the anti-adipogenic effects of SH21B may be the modulation of genes involved in cell proliferation and adipogenesis.