• 제목/요약/키워드: DDE

검색결과 121건 처리시간 0.027초

환경호르몬인 p,p-DDE의 흡입 시 ICR 마우스의 폐에 미치는 독성병리학적 연구 (Toxico-pathological Study p,p-DDE After Experimental Aerosol Exposed to ICR Mouse)

  • 최해윤;정태영;구세광;양희복;이형식
    • Toxicological Research
    • /
    • 제21권2호
    • /
    • pp.151-160
    • /
    • 2005
  • In order to monitor the histological and general profiles of lung after direct expose of p,p-DDE, 1, 5 and 10 mg/ml of p,p-DDE were sprayed to male ICR mouse, and seven days after exposure, changes of body weight, lung weight, clinical signs, histological profiles of lung and total WBC in blood were investigated with changes of total cell number and their differential count in bronchoalveolar lavage fluid (BALF). In the present study, a significant and dosage-dependent decrease of body weight was detected in p,p-DDE exposed groups and body weight gains during observational periods (7 days) were also significantly and dosage-dependently decreased in p,p-DDE exposed groups compared to that of vehicle control group. In addition general depression signs were detected in all p,p-DDE exposed groups with dosage-dependent manners, and lung weights were also increased in p,p-DDE exposed groups. Congestion, hemorrhage and severe exudate were observed in the lung of p,p-DDE exposed groups with sarcomatous changes and these signs were also showed by dosage-dependent manners. In addition, foreign body pneumonia signs were observed in the lung of p,p-DDE exposed groups in histological levels. The percentage of ALSA (Area of luminal surface of alveoli) was also significantly and dosage-dependently decreased in p,p-DDE exposed groups and total blood WBC and BALF cell numbers were significantly and dosage-dependently increased in p,p­DDE exposed groups compared to that of vehicle control group and increase percentage of neutrophil, eosinophil, and lymphocyte in BALF were monitored in p,p-DDE exposed groups compared to that of vehicle control group. In conclusion, severe allergic response and/or foreign body pneumonitic changes were induced by direct exposure of p,p-DDE containing beverage. So it is considered that strong and powerful regulation was need to control production of residence of environmental pollutant especially to p,p-DDE.

경북 상주의 인삼 재배환경 중 유기염소계 농약 및 중금속의 잔류 (Residues of the Organochlorine Pesticides and Heavy Metal in Culture Environment of Ginseng on Sangju)

  • 김정호
    • Environmental Analysis Health and Toxicology
    • /
    • 제19권2호
    • /
    • pp.183-189
    • /
    • 2004
  • To obtain the residual organochlorine pesticides in the culture environment of ginseng on Sangju, Gyeongbuk, the analytical methods for BHC isomers, Aldrin, DDE, Dieldrin, DDD, Endrin and DDT by GCECD are surveyed. The relative retention times for $\alpha$-BHC, $\beta$-BHC, ${\gamma}$-BHC, $\delta$-BHC, Aldrin, DDE, Dieldrin, DDD, Endrin and DDT were 1.000, 1.042, 1.049, 1.086, 1.202, 1.335, 1.341, 1.371, 1.391 and 1.439, respectively The BHC isomers, Aldrin, DDE, Dieldrin, DDD, Endrin and DDT were separated on the base line. The qualified detection concentration for $\alpha$-BHC, $\beta$-BHC, ${\gamma}$-BHC and $\delta$-BHC is 0.43, 1.33, 0.54 and 1.63 ng/g and it's of Aldrin, DDE, Dieldrin, DDD, Endrin and DDT were 0.63, 0.50, 0.66, 0.74, 0.96 and 0.88ng/g, respectively. BHC isomers, Aldrin, DDE, Dieldrin, DDD, Endrin and DDT were not detected in culture environment of ginseng on Sanaju, Gyeongbuk. The detection concentration for Hg, Cd, Pb, Cr, and As in ginseng were 0.0086ppm, 0.0020ppm, 0.0200ppm, 0.0271ppm and 0.0220ppm, respectively, which were also lower than the 30ppm Korea Food & Drug Administration advisory level for heavy metal in herbal medicines.

VDPM을 이용한 PMBA/4,4-DDE polyimide의 제작과 전기적특성 (Fabrication and Electric characteristics of PMDA/4,4-DDE Polyimide by Vapor Deposition Polymerization(VDP) Method)

  • 김형권;우호환;김종석;한상옥;이덕출
    • 한국전기전자재료학회:학술대회논문집
    • /
    • 한국전기전자재료학회 1995년도 추계학술대회 논문집
    • /
    • pp.139-142
    • /
    • 1995
  • Polyimide(PI) thin films are fabricated by vapor deposition polymerization(VDP) from PMDA and DDE. The IR spectrum show that PAA the films are changed into PI films by curing. The activation energy of PI films is estimated to be 0.32 [eV] at the electric field of 0.133 [Mv/cm]. The resistivity is about 4.5${\times}$10$\_$16/ [$\Omega$$.$cm] at room temperature.

  • PDF

천해환경에서 적응 알고리즘을 이용한 음향 등화기의 성능 비교 (Performance Comparison of Acoustic Equalizers using Adaptive Algorithms in Shallow Water Condition)

  • 췌명;박규칠
    • 한국정보통신학회논문지
    • /
    • 제22권2호
    • /
    • pp.253-260
    • /
    • 2018
  • 천해 환경에서의 수중 음향 통신 채널은 전형적으로 시변 다중 경로 페이딩 채널 특성을 나타낸다. 이러한 채널 전송을 통해 수신된 신호는 시간 지연 및 진폭의 중첩에 의해 심볼 간 간섭을 유발한다. 이를 보완하기 위해 여러 기술이 사용되었으며, 그 중 하나가 음향 등화기이다. 본 연구에서는 심볼 간 간섭을 보상하기 위해 feed-forward equalizer (FFE), decision direct equalizer (DDE), decision feedback equalizer (DFE) 및 DFE와 결합된 DDE의 4 종류의 등화기와 등화기의 계수를 조정하기 위해 normalized least mean square (NLMS) 알고리즘과 recursive least square (RLS) 알고리즘의 2 종류의 알고리즘을 적용하였다. 그 결과 비선형 등화기에서는 신호 대 잡음비 6 dB 이상에서 상당한 성능 향상을 발견할 수 있었으며, DFE와 DDE의 조합은 어떤 경우에도 최고의 성능을 발휘하였다.

등줄쥐를 이용한 육상환경 중의 PCBs와 DDE의 오염평가 (Evaluation of PCBs and DDE contamination in terrestrial environment using striped field mouse, Apodemus agrarius)

  • 윤명희;김민관;민병윤;최재원
    • 한국환경과학회지
    • /
    • 제9권3호
    • /
    • pp.201-208
    • /
    • 2000
  • PCBs and DDE were determined in the soil samples and the Korean striped field mice, Apodemus agrarius, collected at six localities in Changwon and one locality in Gaduck Island from August 1997 to May 1998. The residual level of PCBs in soils, in which the concentrations of high chlorinated compounds were much higher than those of low chlorinated ones, was highest in the industrial area(IA) in Changwon(60.7 ng/g in average), whereas those of DDE in soils was highest in Gaduck Island(331.9 ng/g in average). However, the levels of each compound detected from soils in the respective remaining places were relatively low. The similar tendency as in the soils was observed in the mice, indicating that the concentration of pollutants in the mice could denote the status of pollution in the terrestrial environment. The composition of PCB congeners in the mice, however, was different from that of soils, but similar to those of other mammals. Moreover, the residual levels of PCBs and DDE in pregnant females from which fetuses were removed were lower than those of males and non-pregnant females. It suggests that these compounds accumulated in pregnant females might have been transferred to the fetuses through placenta as in other mammals. Judging from the above facts, it is suggested that the striped field mouse can be an useful biological index to evaluate the contamination in mammals inhabiting terrestrial environment.

  • PDF

수증기(水蒸氣) 증류법(蒸溜法)에 의(依)한 토양중(土壤中) 유기염소계(有機鹽素系) 살충제의 잔류분(殘留分) 평가(評價) (Evaluation of Organochlorine Pesticide Residues in Soil by Steam Distillation)

  • 서용택;심재한;박노동
    • 한국환경농학회지
    • /
    • 제3권2호
    • /
    • pp.23-29
    • /
    • 1984
  • 수증기증류법(水蒸氣蒸溜法)으로 추출(抽出)하고 GLC-ECD를 사용(使用)하여 전라남도(全羅南道) 경작지(耕作地) 토양시료(土壤試料) 121점(點)(plastic film house 59, 밭 30, 과수원(果樹園) 32점(點)) 중의 6가지 유기염소계(有機鹽素系) 살충제 (${\gamma}-BHC$, heptachlor, dieldrin, p,p'-DDE, p,p'-DDD, p,p'-DDT)의 잔류분(殘留分)을 분석평가(分析評價)하였다. 총평균잔류량(總平均殘留量)은 과수원(果樹園)이 0.415ppm, plastic film house가 0.234ppm, 밭 토양(土壤)이 0.158ppm이었다. 전체(全體) 잔류수준(殘留水準)의 94%를 p,p'-DDT와 그 동족체(同族體)(p,p'-DDE, p,p'-DDD)가 차지했고, ${\gamma}-BHC$는 모든 공시토양(供試土壤)에서 검출(檢出)되었으며 검출범위는 $trace{\sim}0.050ppm$이었다. 총(總) 평균잔류양(平均殘留量)은 $p,p'-DDD>p,p'-DDT>dieldrin{\approx}heptachlor>{\gamma}-BHC{\approx}p,p'-DDE$ 순(順)이었다.

  • PDF

인삼 중 DDT(DDD 및 DDE) 분석법의 개발 (Development of a Simultaneous Analysis Method for DDT (DDD & DDE) in Ginseng)

  • 김성단;조태희;한은정;박성규;한창호;조한빈;최병현
    • 한국식품과학회지
    • /
    • 제40권2호
    • /
    • pp.123-128
    • /
    • 2008
  • GC-${\mu}$ECD 이용한 수삼, 건조인삼, 홍삼 중 DDT(o,p'-DDE, p,p'-DDE, o,p'-DDD, p,p'-DDD, o,p'-DDT, p,p'-DDT)의 효율적인 분석방법을 살펴본 결과는 다음과 같다. 단순하며 소량의 용매를 사용하는 동시분석법을 이용하여 인삼으로부터 DDT(DDD 및 DDE포함)를 추출하고 헥산 및 6% 에테르 함유 헥산으로 SPE-Florisil(500 mg) 정제하는 것이 GC-${\mu}$ECD 크로마토그램에서 인삼고유성분과 DDT(DDD 및 DDE포함) 피크의 분리도와 회수율 측면에서 가장 효율적이었다. 또한 인삼 중 저농도(0.01-0.05 mg/kg) DDT(DDD 및 DDE포함) 이성질체를 SPE-Florisil(500 mg) 정제 전 30% 황산 처리 후 원심분리로 인삼 고유성분을 제거하여 정확성을 높였다. 동시다성분법 추출 후 황산처리 및 SPE-Florisil(500 mg) 정제방법을 이용한 수삼, 건조 인삼분말, 홍삼분말에 DDT(DDD 및 DDE포함) 이성질체 표준용액을 0.01 mg/kg 농도가 되도록 첨가하여 실험한 회수율은 87.9-99.6%이었으며 표준편차는 0.9-5.9%였다. 또한 검출한계(Method Detection Limits)는 0.003-0.009 mg/kg이었다.

한국인 제2형 당뇨병 환자를 위한 칼로리별 표준식단 적용효과 (Application Effect in Standard Diet by Calorie for Korean Type 2 Diabetic Patients)

  • 심기현;한영실
    • 한국식품조리과학회지
    • /
    • 제21권1호
    • /
    • pp.64-74
    • /
    • 2005
  • To develop the diet for Korean type 2 diabetic patients, a consumer survey was conducted (N=35) and was analyzed statistically. The survey compared the results of a questionnaire, somatometry, and blood parameters before and 8 weeks after the experiment. It was divided into Diabetic diet enforcement group (DDE) vs. Non diabetic diet enforcement group (NDDE). There was no significant difference in body weight, body mass index (BMI), body fat, triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) of the subjects before and 8 weeks after the experiment. DDE's average fasting glucose (FBG) and post prandial 2 hours blood glucose (PP2) were significantly decreased before and after the experiment (p<0.05). NDDE's average FBG and PP2 showed no significant difference. In terms of Hemoglobin $A_lC\;(HbA_1C)$ content, DDE's had significantly decreased level both before and after the experiment (p<0.05), while there was no significant difference in the NDDE group. Cholesterol and High density lipoprotein cholesterol (HDL-C) were significantly different in DDE (p<0.05) both before and after the experiment. Whereas in the case of NDDE, there was no significant difference on the cholesterol and HDL-C, while DDE's showed a significant difference before and after the experiment. In terms of patients distribution depending on their treatment (p<0.05), NDDE had no significant difference before and after the experiment. For an item asking blood glucose control, DDE had significant difference before and after the experiment (p<0.01), while NDDE had no significant difference. For program satisfaction (p<0.05) and health (p<0.001), both the groups changed significantly after the experiment. But there was no significant difference in applying it to their real life after the experiment. Based on these results, DDE had the decreased blood glucose levels, $HbA_1C$, and cholesterol and increased HDL-C, with decreased rate of the patients taking oral hypoglycemic agents. In addition, many of the patients who participated in the experiment were found to be satisfied with the program, in terms of having less trouble in glucose control and exhibited improvement in health. Hence, based on the above results it was concluded that program was a very successful one for the treatment of diabetes.