• Title/Summary/Keyword: DCI

Search Result 69, Processing Time 0.027 seconds

The DCiF Model and Credit Evaluation on Korean Construction Companies (건설기업 신용평가에 있어서 DCiF 모델의 활용에 관한 연구)

  • Park Tong-Kyu
    • Korean Journal of Construction Engineering and Management
    • /
    • v.5 no.4 s.20
    • /
    • pp.97-106
    • /
    • 2004
  • Credit evaluation by domestic financial institutions on Korean construction companies has had many problems with its tools and criteria ignoring the industrial characteristics. This study develops the DCiF(discounted cash inflow) model as a solution and discusses its usage in construction financing. It also examines the significance of the DCiF indices through regressions and statistical comparison with the other credit evaluation estimates. The results show its clear significance and consistent fitness. Based on the empirical results, implications and methodology are provided for the effective use of the indices in credit evaluation on the construction companies.

Influence of Dichloroisoproterenol and Panax Ginseng on the action of some drugs. (Dichloroisoproterenol및 인삼(人蔘)의 이삼약물(二三藥物)의 작용(作用)에 미치는 영향(影響))

  • Chun, Yun-Sook;Choi, Baik-Hi;Kim, Chi-Euk;Lim, Kyu-Bok;Choi, Kyung-Hun
    • The Korean Journal of Pharmacology
    • /
    • v.2 no.1 s.2
    • /
    • pp.21-29
    • /
    • 1966
  • Dichloroisoproterenol(DCI) i; one of the well known ${\beta}$-adrenergic receptor blocking agents. According to Moran and Perkins, DCI has sympathomimetic like action in relatively low concentrations. Fleming and Hawkins confirmed that DCI acts upon the receptors concerned with positive chronotropic and inotropic actions in the heart. Vogins reported that DCI, in concentration of $5{\times}10^{-8}$ to $5{\times}10^{-6}g/ml$, had properties of sympathomimetic amine causing positive inotropic and chronotropic actions in normal rat atria. And James and Nadeau found that DCI had not only adrenergic blocking effect in moderate and higher concentrations, but it also blocked the effect on the sinus node by vagal stimulation and of directly administered acetylcholine in higher concentrations. As stated above by many authors, DCI has complicated actions according to its concentrations. Our aim at the present experiments was to study the effects of DCI to the action of ouabain and acetylcholine upon the excised rabbit atria, as well as to the action of barium chloride and acetylcholine upon the excised rabbit intestine. In addition, Pan ax Ginseng is widely used as tonics in oriental nations, its pharmacological action, however, has not been clearly established. So we atempted to investigate the effects of the water extract of Panax Ginseng to the action of ouabain and DCI upon both atria and intestine. The results obtained were as follows. 1) DCI has a negative inotropic effect on the excised rabbit atria at concentration of $10^{-5}$ and a positive inotropic effect at concentration of $10^{-6}$. 2) DCI (at concentration of $10^{-6}$) potentiates the positive inotropic effect of ouabain upon the excised rabbit atria. 3) DCI antagonizes the action of acetylcholine upon the excised rabbit atria. 4) The water extract of Panax Ginseng, at concentration of $10^{-3}$, decreases the contractile force of rabbit atria, and tends to slightly increase that of rabbit atria at $10^{-4}$. 5) The water extract of Panax Ginseng exhibits a synergistic action with ouabain on the contractile force of rabbit atria. 6) DCI, in concentrations of $10^{-7}{\sim}10^{-6}$, depresses the tone and amplitude of contraction of the excised rabbit intestine. The depression of the intestinal tone markedly appears in pretreatment with reserpine 2mg/kg 24 hours. 7) DCI antagonizes the contractile effect of barium chloride on the excised rabbit atria. 8) DCI has no significant influence on the action of acetylcholine upon the excised rabbit intestine. 9) The series of those evidences indicates that DCI has a sympathomimetic-like action and more over a relaxing action directly on the excised rabbit intestine. 10) The water extract of Panax Ginseng in concentrations of $10^{-4}{\sim}10^{-3}$, has transient depression of the intestinal tone, but later gradually recovers its normal motility: 11) The water extract of Panax Ginseng has a synergistic action with ouabain on the intestinal contractility.

  • PDF

The Spectroscopic Studies on the Aggregation Behavior of Cyanine Dyes

  • 민형식;박정희;유종완;김동호
    • Bulletin of the Korean Chemical Society
    • /
    • v.19 no.6
    • /
    • pp.650-654
    • /
    • 1998
  • Aggregations of 1,1'-diethyl-2,2'-carbocyanine iodide (DCI) and 1,1'-diethyl-2,2'-dicarbocyanine iodide (DDT) in aqueous solution have been investigated by the steady-state absorption spectroscopy. The equilibrium constants for dimerization of DCI and DDT are found to be $(9.8{\pm}0.5){\times}10^4 \;and\; (1.6{\pm}0.5){\times}10^5\; M^{-1}$, respectively, at 293 K. The enthalpy changes for the dimerization of DCI and DDT are -6.7±0.7 and -7.7±0.8 kcal/mol, respectively. The results show that the dispersion force plays an important role in the aggregation of DCI and DDT in aqueous solution. The absorption bandwidth of DCI/ethanol system has been measured as a function of temperature, providing the evidence for no strong interaction between DCI and solvent molecules. The participation of hydrophobic force in driving the aggregation is suggested. For the first time, DCI in aqueous solution is found to form a new aggregate which has both J- and H- bands.

The Possibility of Drought Expression by Late March Dryness in Rice Paddy Areas Using Terra MODIS NDVI (Terra MODIS NDVI를 활용한 3월말 논지역 건조상태에 따른 가뭄표현 가능성 연구)

  • LEE, Ji-Wan;LEE, Yong-Gwan;KIM, Seong-Joon
    • Journal of the Korean Association of Geographic Information Studies
    • /
    • v.20 no.3
    • /
    • pp.27-41
    • /
    • 2017
  • The purpose of this study is to diagnose the possibility of future drought expression by late March dryness in rice paddy areas using Terra MODIS NDVI (Normalized Difference Vegetation Index). We tested the degree of dryness by comparing the 2000-2015 average NDVI with yearly NDVI, which we name DCI (Dry Condition Index). The 16-day interval DCIs from March 6 to May 25 were evaluated with spatio-temporal expression of South Korea. In particular, we find that the DCI for April 7 (March 23 to April 7) offered reasonable prediction of paddy dryness during drought years. The April 7 DCI value for dry conditions ranged from 0.04 to 0.08 while the DCI for normal conditions ranged from -0.04 to 0.01. The DCI can be one of the indicators used to evaluate the dryness of rice paddy areas at the beginning of the spring season.

Effects of Alloying Elements on the High Pressure Wear Characteristics of Ductile Cast Iron I-Cu, Mn (구상흑연주철의 고압하 마멸특성에 미치는 합금원소의 영향 I-Cu, Mn)

  • Bang, Woong-Ho;Kang, Choon-Sik;Park, Jae-Hyun;Kweon, Young-Gak
    • Journal of Korea Foundry Society
    • /
    • v.20 no.4
    • /
    • pp.230-239
    • /
    • 2000
  • High pressure wear characteristics of DCI(Ductile Cast Iron) were investigated through unlubricated pin-on-disc wear test. Wear test were carried out at speed of 23m/min, under pressure of 3MPa and 3.3 MPa. Cu and/or Mn were added to examine the effect of alloying elements on the high pressure wear characteristics of DCI. To investigate the relationship between wear characteristics and mechanical properties of DCI, Brinell hardness and V-notched Charpy impact energy were tested. Wear surface of each specimen was observed by SEM to determine the wear mechanism of DCI under high pressure wear condition. In the mild wear region, wear characteristics of alloyed DCI specimens were very similar to that of unalloyed DCI. But mild-severe wear transition was occurred at different wear distance and wear rate of DCI specimens were changed by alloying elements. In severe wear condition, wear rate of DCI was dramatically increased by the addition of Mn. Although the addition of Cu 0.46wt% did not decrease the wear rate of DCI in the severe wear region, but it delayed the mild-severe wear transition. Under high pressure wear condition, wear rate and mild-severe wear transition were not concerned with hardness of DCI specimens, but they were deeply associated with impact energy changed by alloying elements.

  • PDF

The Effect of Austempering Treatment on Microstructure and Mechanical Properties of NICI and DCI for Rolls Used in Hot Rolling Mill (오스템퍼링 처리가 열간압연롤용 NICI재 및 DCI재의 미세조직 및 기계적 성질에 미치는 영향)

  • Kim, Jae-Jin;Oh, Seok-Jung;Yoo, Kook-Jong;Andy, Tirta;Baek, Eung-Ryul
    • Journal of Korea Foundry Society
    • /
    • v.29 no.6
    • /
    • pp.251-256
    • /
    • 2009
  • The effect of austempering treatment on mechanical properties of nodular indefinite chilled iron(NICI) and ductile cast iron(DCI) was investigated. In microstructural observation, matrix phase(pearlite and ferrite) was changed to ausferrite after austempering treatment both DCI and NICI. In case of NICI, decomposition of cementite($Fe_3C$) during austempering treatment was induced. After austempering treatment, mechanical properties such as hardness, tensile strength and impact toughness was improved in NICI and DCI. The wear resistance is slightly decreased because of decomposition of cementite during austempering treatment in NICI but impact toughness and strength is dramatically increased.

Inhibitory Effect of D-chiro-inositol on Both Growth and Recurrence of Breast Tumor from MDA-MB-231 Cancer Cells

  • Kim, Yoon-seob;Park, Ji-sung;Kim, Minji;Hwang, Bang Yeon;Lee, Chong-kil;Song, Sukgil
    • Natural Product Sciences
    • /
    • v.23 no.1
    • /
    • pp.35-39
    • /
    • 2017
  • D-chiro-inositol (DCI) is a secondary messenger in insulin signal transduction. It is produced in vivo from myo-inositol via action of epimerase. In this study, we evaluated antitumor activity of DCI against human breast cancer both in vitro and in vivo. In order to determine the inhibitory effects of DCI on growth of human breast cancer cells (MDA-MB-231), two different assessment methods were implemented: MTT assay and mouse xenograft assay. MTT assay demonstrated downturn in cell proliferation by DCI treatment (1, 5, 10, 20 and 40 mM) groups by 18.3% (p < 0.05), 17.2% (p < 0.05), 17.5% (p < 0.05), 18.4% (p < 0.05), and 24.9% (p < 0.01), respectively. Also, inhibition of tumor growth was investigated in mouse xenograft model. DCI was administered orally at the dose of 500 mg/kg and 1000 mg/kg body weight to treat nude mouse for 45 consecutive days. On the 45th day, tumor growth of DCI (500 mg/kg and 1000 mg/kg) groups was suppressed by 22.1% and 67.6% as mean tumor volumes were $9313.8{\pm}474.1mm^3$ and $3879.1{\pm}1044.1mm^3$, respectively. Furthermore, breast cancer stem cell (CSC) phenotype ($CD44^+/C24^-$) was measured using flow cytometry. On the 46th day, CSC ratios of DCI (500 mg/kg) and co-treatment with doxorubicin (4 mg/kg) and DCI (500 mg/kg) group decreased by 24.7% and 53.9% (p < 0.01), respectively. Finally, from tumor recurrence assay, delay of 5 days in the co-treatment group compared to doxorubicin (4 mg/kg) alone group was observed. Based on these findings, we propose that DCI holds potential as an anti-cancer drug for treatment of breast cancer.

Visually Lossless Image Compression for Digital Cinema Distribution Based on DCI Specification (DCI 규격을 만족하는 디지털시네마 배급을 위한 시각적 무손실 압축 연구)

  • Kim, Chul-Hyun;Paik, Joon-Ki
    • Journal of Broadcast Engineering
    • /
    • v.13 no.1
    • /
    • pp.99-108
    • /
    • 2008
  • This raper analyzes the effect of visually lossless image compression for efficient distribution of digital cinema. Currently, distribution of digital cinema is carried out based on JPEG 2000 standard that has been selected by DCI. We first summarize characteristics of JPEG 2000, and then define the concept of visually lossless coding that plays an important role in digital cinema distribution. We provide a test for JPEG 2000 compression performance according to DCI specification for visually lossless. Based on the experiment, the result satisfies high quality for cinema distribution.

Monocyte Count and Systemic Immune-Inflammation Index Score as Predictors of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

  • Yeonhu Lee;Yong Cheol Lim
    • Journal of Korean Neurosurgical Society
    • /
    • v.67 no.2
    • /
    • pp.177-185
    • /
    • 2024
  • Objective : Delayed cerebral ischemia (DCI) is a major cause of disability in patients who survive aneurysmal subarachnoid hemorrhage (aSAH). Systemic inflammatory markers, such as peripheral leukocyte count and systemic immune-inflammatory index (SII) score, have been considered predictors of DCI in previous studies. This study aims to investigate which systemic biomarkers are significant predictors of DCI. Methods : We conducted a retrospective, observational, single-center study of 170 patients with SAH admitted between May 2018 and March 2022. We analyzed the patients' clinical and laboratory parameters within 1 hour and 3-4 and 5-7 days after admission. The DCI and non-DCI groups were compared. Variables showing statistical significance in the univariate logistic analysis (p<0.05) were entered into a multivariate regression model. Results : Hunt-Hess grade "4-5" at admission, modified Fisher scale grade "3-4" at admission, hydrocephalus, intraventricular hemorrhage, and infection showed statistical significance (p<0.05) on a univariate logistic regression. Lymphocyte and monocyte count at admission, SII scores and C-reactive protein levels on days 3-4, and leukocyte and neutrophil counts on days 5-7 exhibited statistical significance on the univariate logistic regression. Multivariate logistic regression analysis revealed that monocyte count at admission (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.04-2.65; p=0.036) and SII score at days 3-4 (OR, 1.55; 95% CI, 1.02-2.47; p=0.049) were independent predictors of DCI. Conclusion : Monocyte count at admission and SII score 3-4 days after rupture are independent predictors of clinical deterioration caused by DCI after aSAH. Peripheral monocytosis may be the primer for the innate immune reaction, and the SII score at days 3-4 can promptly represent the propagated systemic immune reaction toward DCI.

The impact of collateral status on cerebral vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage

  • Abdullah Topcu;Ayca Ozkul;Ali Yilmaz;Ho Jun Yi;Dong Seong Shin;BumTae Kim
    • Journal of Cerebrovascular and Endovascular Neurosurgery
    • /
    • v.25 no.3
    • /
    • pp.288-296
    • /
    • 2023
  • Objective: Cerebral collateral circulation may affect subarachnoid hemorrhage (SAH) induced cerebral vasospasm and delayed cerebral ischemia. In this study our aim was to investigate the relationship between collateral status, vasospasm and delayed cerebral ischemia (DCI) in both aneurysmal and nonaneurysmal SAH. Methods: Patients diagnosed as SAH with and without aneurysm were included and their data investigated retrospectively. After the patients diagnosed as SAH according to cerebral computed tomography (CT)/magnetic resonance imaging (MRI), they underwent cerebral angiography to check for cerebral aneurysm. The diagnosis of DCI was made according to the neurological examination and control CT/MRI. All the patients had their control cerebral angiography on days 7 to 10 in order to assess vasospasm and also collateral circulation. The American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology (ASITN/SIR) Collateral Flow Grading System was modified to measure collateral circulation. Results: A total of 59 patients data were analyzed. Patients with aneurysmal SAH had higher Fisher scores and DCI was more common. Although there was no statistically significant difference between the patients with and without DCI in terms of demographics and mortality, patients with DCI had worse collateral circulation and more severe vasospasm. These patients had higher Fisher scores and more cerebral aneurysm overall. Conclusions: According to our data, patients with higher Fisher scores, more severe vasospasm, and poor cerebral collateral circulation may experience DCI more frequently. Additionally aneurysmal SAH had higher Fisher scores and DCI was seen more common. To improve the clinical results for SAH patients, we believe that physicians should be aware of the DCI risk factors.