• Proceedings of the KSRS Conference
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• 2007.10a
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• pp.479-481
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• 2007

COMS will transmit its observed data, Sensor Data, through L-Band with linear polarization. To avoid link loss caused by polarization discrepancy between satellite and SOC DATS, the L-Band antenna at SOC DATS should be linearly polarized. However, SOC DATS is supposed to share single antenna with SOC TTC, so the antenna should be circularly polarized. To cope with about 3dB loss, SOC DATS is designed to receive Sensor Data through two orthogonal circular polarizations, RHCP (Right-Hand Circular Polarization) and LHCP (Left-Hand Circular Polarization). Eventually, SOC DATS can obtain 2.6dB of combining gain through diversity combiner in MODEM/BB. This paper presents the verification on the diversity combining of SOC DATS with test configuration and results in depth.

• Journal of Astronomy and Space Sciences
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• v.25 no.4
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• pp.459-470
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• 2008

DATS which is one of three subsystems of IDACS is responsible to receive Sensor Data, LRIT and HRIT in L-Band and transmit LRIT and HRIT in S-Band from/to COMS satellite. This paper shows detailed test procedures used to verify the performance and functionality of DATS after its implementation was completely finished. As a part of efforts to verify key DATS performance, G/T and EIRP were measured by using solar flux density as radio source. Regarding the verification of DATS functionality, RF loop-back test was conducted to validate if there is no BER degradation excepting MODEM/BB implementation loss occurred in the integrated DATS. Integrated with 13m antenna, DATS successfully restored image from received MTSAT-1R broadcasting data, LRIT and HRIT, of which frequencies are all L-Band. S-Band transmission was also verified through test antenna placed away from 13m antenna by measuring real LRIT and HRIT spectrum in S-Band. From those test results, DATS is determined to be fully ready to communicate with COMS in L-Band and S-Band.

• Proceedings of the KSRS Conference
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• 2007.10a
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• pp.602-605
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• 2007

COMS SOC is supposed to operate IDACS as a backup of MSC. For the backup operation, there is a route between SOC and MSC for exchanging current version such as radiometric calibration for IMPS, dissemination schedule, encryption key and conversion table for LHGS. DATS C&M S/W is basically designed to control and monitor DATS equipment. However, its capability is extended to monitor the working status of IMPS, LHGS and even MSC IDACS. In addition, DATS C&M SIW can display discrepancy between MSC and SOC when applied version is different each other. This paper presents detailed description on the development of DATS C&M S/W.

• Journal of Life Science
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• v.23 no.5
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• pp.622-628
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• 2013

Diallyl trisulfide (DATS), one of the major organosulfur components of garlic (Allium sativum), has various biological effects such as anti-microbial and anti-cancer activities. However, the molecular mechanisms of growth inhibition related to cell cycle arrest are poorly understood. In this study, we investigated the effects of DATS on cell cycle progression in U937 human leukemia cells. Treatment with DATS in U937 cells resulted in inhibition of cell viability through G2/M arrest and apoptosis. DATS-induced G2/M arrest was associated with up-regulation of cyclin B1 and cyclin-dependent kinase 1 (CDK1). DATS also significantly increased levels of phospho-histone H3, which is a mitosis-specific marker, indicating that DATS induced mitotic arrest but not G2 arrest in U937 cells. DATS treatment also generated the reactive oxygen species (ROS) in U937 cells; however, pretreatment with N-acetyl-l-cysteine (NAC), a ROS scavenger, significantly attenuated DATS-induced mitotic arrest and apoptosis. Taken together, our data indicate that DATS exhibits anti-cancer effects through mitotic arrest and apoptosis in a ROS-dependent manner.

• Journal of Astronomy and Space Sciences
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• v.26 no.1
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• pp.127-140
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• 2009

COMS DATS C&M software is an integrated management system providing control and monitoring functionalities for COMS IDACS (Image Data Acquisition and Control System). DATS C&M S/W consists of a system management module, a control and monitoring module, a data management module, and a trend analysis module. COMS SOC is supposed to operate IDACS as a backup of MSC. Especially, for the backup operation, the control and monitoring module of DATS C&M S/W is designed to support the synchronization of the two IDACS systems. This paper describes design, implementation, and result of development of DATS C&M S/W.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.113-113
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• 2019

Diallyl trisulfide (DATS) is an organic polysulfide compound found in garlic. Although certain studies have demonstrated that DATS possesses strong anti-inflammatory activity, the underlying molecular mechanisms remain largely unresolved. In this study, we examined whether DATS exerts anti-inflammatory activity and investigated the possible mechanisms. Our results indicated that DATS significantly suppressed the lipopolysaccharide (LPS)-induced release of nitric oxide (NO) and prostaglandin E2 by inhibiting inducible NO synthase and cyclooxygenase-2 expression at the transcriptional and post-transcriptional levels in RAW 264.7 macrophages. DATS also down-regulated Toll-like receptor 4 (TLR4) and myeloid differentiation factor 88 expression, and inhibited nuclear translocation of nuclear transcription factor-kappa B (NF-${\kappa}B$) in LPS-stimulated 264.7 macrophages. Furthermore, we found that these inhibitory effects of DATS were associated with the inhibition of chemokine receptor (CXCR4) and ligand (CXCL12) expression, and reactive oxygen species generation. Overall, the present data indicated that DATS had anti-inflammatory effects on LPS-activated macrophages, possibly via inhibiting the TLR4/NF-kB and/or chemokine signaling pathways, and DATS could be a potential drug therapy for inflammation and its associated diseases.

• Journal of Life Science
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• v.33 no.4
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• pp.349-356
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• 2023

Gout, a chronic inflammatory arthritic disease, is characterized by hyperuricemia. Gout can be induced by an inflammatory response to monosodium urate (MSU) crystals mediated by pro-inflammatory cytokine release following activation of the NOD-like receptor protein 3 (NLRP3) inflammasome. Many sulfur-containing phytochemical compounds in garlic (Allium sativum L.) are considered active ingredients because of their potential pharmacological benefits for various diseases, but their efficacy in NLRP3 inflammasome activation-mediated gout has not been demonstrated. In this study, we investigated whether diallyl disulfide (DADS) and diallyl trisulfide (DATS), representative garlic-derived sulfur compounds, have an inhibitory effect on MSU-induced NLRP3 inflammasome activation. Our results showed that under non-cytotoxic conditions, DADS and DATS significantly blocked nitric oxide production and interleukin (IL)-1β release in response to MSU in lipopolysaccharide (LPS)-primed RAW 264.7 macrophages. DADS and DATS also attenuated enhanced expression of NLRP3 and its adapter protein, apoptosis-associated speck-like protein, which was associated with downregulation of and caspase-1 p20 and IL-1β expression, suggesting that MSU-induced LRP3 inflammasome activation was counteracted by DADS and DATS. Furthermore, DADS and DATS blocked oxidative stress, an upstream event for NLRP3 inflammasome activation, as evidenced by the fact that they scavenged reactive oxygen species (ROS) production. Taken together, our findings demonstrate that DADS and DATS suppressed NLRP3 inflammasome activation by inhibiting the ROS/NLRP3 pathway and that they have potential as treatments for NLRP3-dependent gouty arthritis.

• Korean Journal of Environmental Agriculture
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• v.33 no.4
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• pp.381-387
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• 2014

BACKGROUND: Garlic (Allium sativum) extract has been allowed as commercial biopesticide material for pesticidal activity in the Environmentally-friendly Agriculture Promotion Act. Nine commercial biopesticides containing A. sativum extract have been marketed in Korea. However, the analytical method of the active substances in these materials has not been studied. METHODS AND RESULTS: Cartridge clean-up method for the determination of dimethyl disulfide(DMDS), diallyl disulfide(DADS), and diallyl trisulfide(DATS) in biopesticides containing A. sativum extract was developed and validated by gas chromatography(GC). The clean-up method was optimized using hydrophilic lipophilic balance (HLB) solid phase extraction(SPE) cartridges for the bioactive sulfides in biopesticides containing A. sativum extract, and the eluate was analyzed to quantify the DMDS, DADS, and DATS using the GC. The developed method was validated, and the LOQ and recovery rates of DMDS, DADS, and DATS were 0.226, 0.063, and $0.051mg\;L^{-1}$ and 80.6, 84.8, and 73.1%, respectively. From the nine commercial biopesticide samples, contents of DMDS, DADS, and DATS were analyzed using the developed method and results showed $2.3mg\;L^{-1}$, respectively. CONCLUSION: The developed method could be used in determining the quality of biopesticides for the manufacture of commercial biopesticides containing A. sativum extract.

• Proceedings of the KSRS Conference
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• v.1
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• pp.204-207
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• 2006

COMS will receive two different meteorological signals in S-Band from IDACS (Image Data Acquisition and Control System) in ground station before transmitting them in L-Band to user station. MODCS (Meteorological Ocean Data Communication Subsystem) in satellite released the value of required PFD (Power Flux Density) to receive two signals. Thus, DATS (Data Acquisition and Transmission Subsystem) needs to send two signals to satellite with a satisfied EIRP. The value of minimum HPA (High Power Amplifier) output power was estimated by subtracting antenna directional gain and path loss between antenna and HPA from the needed EIRP in this paper. Besides the minimum output power of HPA, the maximum output power was also calculated with considering IMD (Inter-Modulation Distortion) characteristics. IMD is always occurred in the output of HPA when LRIT and HRIT are amplified by using single HPA as COMS application. In this paper, the setting of maximum output power was determined when the IMD of modelled HPA was corresponded to the requirement of MODCS.

• Proceedings of the KSRS Conference
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• v.1
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• pp.64-66
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• 2006

DATS will connect with IMPS and LHGS to perform the reception of sensor data and the transmission of user's meteorological data, LRIT and HRIT. MODEM/BB will perform the de-commutation of received sensor data as MI and GOCI raw data according to VCID before sending them to MI and GOCI IMPS, respectively. Especially, MODEM/BB in SOC needs to be connected to six clients that consist of the primary and backup IMPS of MSC, KOSC and SOC. On the other hand, LRIT and HRIT delivered from LHGS are encoded as VITERBI and modulated by MODEM/BB. Considering sensor data transmitted from COMS, the assumed format and size of CADU are described in this paper. Finally, results related to the status of received LRIT and HRIT by frame synchronizer in user station are also described.