• Clinical and Experimental Reproductive Medicine
• /
• v.31 no.4
• /
• pp.225-234
• /
• 2004

Objectives: To evaluate the efficacy of GnRH antagonist cetrorelix in women undergoing controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) and to determine changes in serum hormone concentrations during cetrorelix administration. Methods: We performed a clinical trial on 30 patients undergoing COH with highly purified follicular stimulating hormone (HP-FSH) and gonadotropin releasing hormone antagonist (GnRHant), cetrorelix. FSH was administrated from day 2 or 3 of cycle with fixed dose and adjusted according to individual response. 0.25 mg of cetrorelix was injected daily subcutaneously from stimulation day 5 until the day of hCG administration. Daily ultrasound monitoring was performed for growing follicles and serum levels of luteinizing hormone (LH), estradiol ($E_2$) and progesterone were measured daily during cetrorelix administration. Up to 4 embryos were transferred. Results: Mean age of enrolled patients was $32.0{\pm}3.4$ years (mean $\pm$ S.D.). All of 30 patients underwent oocyte pick-up, and embryo transfer was done in 28 patients. The total and mean numbers of received oocytes were 196 and $6.5{\pm}4.7$, the number of fertilized eggs was 111, and the fertilization rate was 56.6%. Total duration of FSH administration was $9.2{\pm}2.2$ days and mean of $24.3{\pm}7.7$ ampules of HP-FSH was administered. Total duration of cetrorelix administration was $5.7{\pm}1.9$ days. Serum LH and progesterone levels were maintained in the range of $1.4{\sim}2.9\;mIU/mL$ and $0.3{\sim}0.6\;ng/mL$, which respectively reflected effective prevention of premature LH surge. Clinical pregnancies were achieved in 9 patients, and overall clinical pregnancy rate was 30.0% per oocyte retrieval, and 32.1% per embryo transfer. Conclusion: GnRH antagonist is safe and convenient for COH for IVF-ET and effective with optimal pregnancy rate.

• Journal of the Korean earth science society
• /
• v.25 no.6
• /
• pp.474-483
• /
• 2004

This paper analyzed the characteristics of daily ozone variations over Kangreung and Wonju. It was found that the diurnal cycle of ozone over Wonju has a primary ozone peak in the afternoon and a minimum around sunrise, which is a typical diurnal ozone cycle observable in the urban area. However, the cycle over Kangreung shows a primary peak in the afternoon and secondary peak around 3 a.m. The amounts of ozone in the secondary peak is occasionally higher than that in the primary peak. This nocturnal ozone peak is frequently observed year-round, and the highest frequency and extent are observed in spring. The possible cause of this nocturnal ozone increase was investigated using meteorological parameters and the HYSPLIT trajectory model. It was found that the nocturnal ozone peak is highly correlated with strong wind speed, which has led to positive temperature anomaly. The trajectory model revealed that when the secondary peak occurred, the air was originated from the west and a sinking motion subsequently followed. These findings suggested that when the westerly wind is strongest in spring, the polluted airs from urban areas are transported to the upper boundary layer over Kangreung area. In the case of strong wind during the night, nocturnal ozone peaks were produced by active vertical mixing between lower boundary and upper boundary layers.

• Asian-Australasian Journal of Animal Sciences
• /
• v.13 no.9
• /
• pp.1205-1209
• /
• 2000

The present study was undertaken to investigate the effect of stimulation of follicular development with eCG on the peripheral levels of inhibin and FSH in Murrah buffaloes. Estrus was synchronized in five normally cycling females by insertion of Crestar (Intervet, Boxmeer, Holland) implants for nine days. Estradiol valerate was administered i.m. on the day of implant insertion. On the 10th day of the induced estrous cycle a single dose of 3000 IU eCG (Folligon, Intervet, Boxmeer, Holland) was given, followed by treatment with 25 mg of $PGF_2$ alpha (Lutalyse, Upjohn, Belgium) 48 h later. Blood samples were obtained during the induced estrus, on cycle day 10 (luteal phase), at the superovulatory estrus (43 h after PGF) and during the periovulatory period (64 h after PGF). Ultrasonography was done daily to monitor follicular development. Plasma concentrations of inhibin and FSH were determined by specific radioimmunoassays. Differences between $mean{\pm}SEM$ values of different phases of the cycle were compared by ANOVA. The mean number of small (2-5 mm), medium (6-9 mm) and large (>10 mm) follicles observed two days after eCG treatment and on the day of superovulatory estrus was $2.8{\pm}0.31$, $5.2{\pm}0.30$ and $1.4{\pm}0.09$ and $1.9{\pm}0.21$, $2.8{\pm}0.40$ and $5.0{\pm}0.83$, respectively. The mean number of ovulations was $3.6{\pm}0.37$ and the mean number of unovulated follicles was $6.1{\pm}0.47$. Most of the follicles >10 mm in diameter had ovulated (72%). The mean ${\pm}SEM $ of plasma inhibin concentration $(2584.15{\pm}17.92pg/ml)$ during the superovulatory estrus was significantly higher $(p{\leq}0.05)$ than during the induced estrus $(749.87{\pm}17.29pg/ml)$, the luteal phase $(1099.54{\pm}24.98pg/ml)$ and periovulatory period $(1682.71{\pm}29.88pg/ml)$, respectively. $Mean{\pm}SEM$ plasma FSH concentration during the induced estrus $(10.35{\pm}0.41ng/ml)$ was not different from that during the superovulatory estrus $(8.52{\pm}0.39ng/ml)$, but was significantly higher $(p{\leq}0.05)$ than during the luteal phase $(2.81{\pm}0.42ng/ml)$ and periovulatory period $(5.7{\pm}0.28ng/ml)$. These data indicate that treatment with eCG in buffaloes for inducing superovulation results in a significant elevation in plasma inhibin levels and a decrease in plasma FSH levels during the superovulatory estrus. Thus, we suggest that the elevated plasma inhibin coming from fully developed follicles continued for a long time which results in inhibition of FSH leading to poor ovulation in the remaining follicles, which may be the cause of suboptimal superovulatory response.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.2 no.1
• /
• pp.1-7
• /
• 1997

We have monitored nutrients, chlorophyll, suspended solids, and salinity in the Keum Estuary to understand the temporal fluctuation of oceanographic parameters and to illustrate any variation due to the gate operation of the Keum River Dike from June, 1995 to September, 1996, approximately for 500 days. Tidal range is used as the key factor to explain the fluctuations and atmospheric parameters such as air temperature, wind velocity and rainfall are also used supplementally. The fresh water discharge was selected as another major impact on the estuarine environment due to the gate operation of the Keum Dike. In addition, daily variation by tidal cycle was investigated twice in April and July, 1996. In diurnal variation, salinity was positively correlated with tidal elevation, whereas negatively correlated with nutrients. Relatively high suspended solid and chlorophyll contents were found in the period between high and low tide. In 500 days continuous observations, salinity was negatively correlated with the volume of fresh-water discharge, but positively correlated with nutrients. A major chlorophyll bloom occurred in spring. A similar pattern of variation was observed between suspended solid and the neap-spring tidal cycle. In comparison with the data of the Keurn Estuary before the gate operation of the Keum River dike, fresh-water discharge predominated other environmental factors during the rainy season. In addition, the velocity of tidal current and the concentration of suspended solid were decreased, while nutrients and chlorophyll contents were increased.

• Journal of the Korean Geographical Society
• /
• v.39 no.6 s.105
• /
• pp.922-932
• /
• 2004

This paper uses the diary entitled Kieo, which was kept by Ryu Hyeong-eop for 38 years, to analyze the active space of small-scale Yangban landlords. Ryu lived during the period spanning from the end of the Taehan Empire through the colonial era. The researcher classified the contents of Kieo into different sections which were divided according to different stages of the writer's life, his objectives, destinations, and periods, and based on the writer's life-cycle, strived to recreate his spatial activities. As a result, researcher was able to ascertain that Ryu's spatial activities gradually increased, and that his active space also continuously expanded. Ryu's active space during his youth was narrow and centered around certain specific places. However, this active space gradually increased as time went by. It was during the middle stages of his life that the volume of his spatial activities was the heaviest. In addition, the objectives of his outings also became more diversified over time. This change was originated in the larger changes in his roles within the family and community, as well as by the changes in the periodic situation. Moreover, the regional sphere of Ryu's outings, including his day and over nights trips, allowed the researcher to form a better understanding of the daily living area of the Yangban.

• Korean Journal of Remote Sensing
• /
• v.37 no.6_1
• /
• pp.1545-1557
• /
• 2021

Crops show sensitive spectral characteristics according to their species and growth conditions and although frequent observation is required especially in summer, it is difficult to utilize optical satellite images due to the rainy season. To solve this problem, Constrained Cloud-Maximum Normalized difference vegetation index Composite (CC-MNC) algorithm was developed to generate periodic composite images with minimal cloud effect. In thisstudy, using this method, monthly Sentinel-2A/B Normalized Difference Vegetation Index (NDVI) composite images were produced for paddies and high-latitude cabbage fields from 2019 to 2021. In August 2020, which received 200mm more precipitation than other periods, the effect of clouds, was also significant in MODIS NDVI 16-day composite product. Except for this period, the CC-MNC method was able to reduce the cloud ratio of 45.4% of the original daily image to 14.9%. In the case of rice paddy, there was no significant difference between Sentinel-2A/B and MODIS NDVI values. In addition, it was possible to monitor the rice growth cycle well even with a revisit cycle 5 days. In the case of high-latitude cabbage fields, Sentinel-2A/B showed the short growth cycle of cabbage well, but MODIS showed limitations in spatial resolution. In addition, the CC-MNC method showed that cloud pixels were used for compositing at the harvest time, suggesting that the View Zenith Angle (VZA) threshold needsto be adjusted according to the domestic region.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.29 no.2D
• /
• pp.235-244
• /
• 2009

Design Value Engineering (VE) has become an import part of the daily design process since it has been introduced in the construction industry. Design VE is usually conducted in the general and execution design stages respectively. In order to increase the effectiveness of the VE process, the outcome from the general design VE activities should be integrated into execution design. The outcome from the execution design should be used again for construction. In this study, a consecutive VE process model has been presented as a way to improve the current practice of design VE activities in the construction industry. In the presented model, follow-up activities are emphasized to increase values from the life-cycle perspective of a construction project. The model was tested in a case study of an actual design VE process. The result of the study demonstrates that the model can: 1) effectively incorporate owners requirements; 2) assist decision making in selecting better construction; 3) increase the interface between general and execution design stages; and 4) trace the value flow more efficiently. Overall, the study results indicates that a the consecutive VE process model can be effectively applied when construction project are contracted for the life-cycle management of construction projects.

• Annals of Occupational and Environmental Medicine
• /
• v.35
• /
• pp.2.1-2.15
• /
• 2023

Background: Phthalates are endocrine disrupting chemicals that are widely used in the production of items of daily life such as in polyvinylchloride plastics, insecticides, and medical devices. This study aimed to determine the association between phthalate exposure and shellfish consumption using data from the Korean National Environmental Health Survey (KoNEHS) cycle 3 (2015-2017), which is a nationally representative survey. Methods: In this study, we analyzed the KoNEHS cycle 3 data of 3,333 (1,526 men and 1,807 women) adults aged more than 19 years. Data related to the variables of sociodemographic factors, health-related behaviors, dietary factors, seafood consumption frequency, and urinary phthalate metabolites concentrations were collected. The concentrations of urinary phthalate metabolites of all the participants were divided into quartiles to define high and low concentration groups based on the 75th percentile concentration. A χ² test was conducted to analyze the distribution of independent variables. To analyze the relationship between shellfish consumption and phthalate exposure, the odds ratios (ORs) were calculated using logistic regression analysis. Results: Total adults with shellfish consumption frequency of over once a week showed the following adjusted ORs for high concentrations of the following metabolites compared with the group that consumed shellfish once a week or less: 1.43 (95% confidence interval [CI]: 1.01-2.06) for mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP), 1.43 (95% CI: 1.01-2.03) for mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP), 1.57 (95% CI: 1.10-2.24) for ∑di-2-ethylhexyl phthalate (∑DEHP), 2.01 (95% CI: 1.46-2.77) for mono-carboxyoctyl phthalate (MCOP), 1.56 (95% CI: 1.11-2.18) for mono-carboxy-isononly phthalate (MCNP), and 2.57 (95% CI: 1.85-3.56) for mono (3-carboxypropyl) phthalate (MCPP). Conclusions: The concentrations of urinary phthalate metabolites (MEOHP, MECPP, ∑DEHP, MCOP, MCNP, and MCPP) were higher in adults with a higher frequency of shellfish consumption.

• The Transactions of the Korean Institute of Electrical Engineers A
• /
• v.52 no.7
• /
• pp.414-420
• /
• 2003

The domestic needs for larger capability of power sources are increasing to cope with the expanding power load which results from the industrial developments & the progressed life style. In summer, the peak load is mainly due to the non-industrial reasons such as air-conditioners and other cooling equipments. To cover the concentrated peak load in stable, the power transmission lines should be more constructed and efficiently operated. The ampacity design of the underground cable system is generally following international standards such as IEC287, IEC60853 and JCS168 which regards the shape of 100% daily full power loads. It is not so efficient to neglect the real shapes of load curves generally below 60~70% of full load. The dynamic (real time) rating system tends to be used with the measured thermal parameters which make it possible to calculate the maximum ampacity within required periods. In this paper, the CTM(Conductor Temperature Monitoring) which is the base of dynamic rating systems for tunnel environment is proposed by a design of lumped thermal network ($\pi$-type thermal model) and distribution temperature sensor attached configuration, including the estimation results of its performances by load cycle test on 345kV single phase XLPE cable.

• The Korean Fashion and Textile Research Journal
• /
• v.14 no.6
• /
• pp.1018-1023
• /
• 2012

Smartphone is integrated into the daily lives of all types of people not even young generation. A touch screen display is a primary input device of a smart phone, a tablet computer, etc. While there are many tough technologies in existence, resistive and capacitive are dominant and currently lead the touch screen panel industry. And a capacitive touch screen panel widely used in smart phones is coated with a material that stores electrical charges. In this study, we tried to manufacture gloves produced with electro-conducting leather as a tool to operate a touch panel screen. Therefore, electrically conductive materials, Polyaniline(PANI), Poly(3,4-ethylenedioxythiophene) (PEDOT), and Carbon nanotubes (CNT) were applied to the surface of leather to be used as a touching operator for capacitive touch screen panel. The leather samples were treated by simple painting method; firstly, they were painted with aqueous solution containing each of the electrically conductive materials and then dried. This cycle was repeated three times. Consequently, the treated leather samples showed electrical conductivity and reasonable working performance to the capacitive touch screen. And, PANI showed the best performance and highest electrical conductivity, and then PEDOT and, CNT in decreasing order. This is because the solubilities of PANI and PEDOT show higher than dispersibility of CNT. Thus, the concentration of conducting polymers was greater than that of CNT in the treating solutions.