• Title/Summary/Keyword: Cyclocondensation

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Synthesis of 2-Arylbenzothiazoles Catalyzed by Biomimetic Catalyst, β-Cyclodextrin

  • Londhe, Balaji S.;Pratap, Umesh R.;Mali, Jyotirling R.;Mane, Ramrao A.
    • Bulletin of the Korean Chemical Society
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    • v.31 no.8
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    • pp.2329-2332
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    • 2010
  • Cyclocondensation of 2-aminothiophenol and aryl/heteryl aldehydes has been carried using biomimetic catalyst, $\beta$-Cyclodextrin in water and obtained 2-aryl/heteryl benzothiazoles with better to excellent yields. This biomimetic catalyzed route is simple, economic, and environmentally benign.

Synthesis and Characterization of 1-Benzofuran-2-yl thiadiazoles, Triazoles and Oxadiazoles by Conventional and Non-conventional Methods (반응방법에 따른 1-Benzofuran-2-yl thiadiazoles, Triazoles과 Oxadiazoles의 합성)

  • Shinde, Ananta D.;Kale, Bhima Y.;Shingate, Bapurao B.;Shingare, Murlidhar S.
    • Journal of the Korean Chemical Society
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    • v.54 no.5
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    • pp.582-588
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    • 2010
  • The synthesis of benzofuran based 1,3,4-thiadiazoles, 1,3,4-triazoles and 1,3,4-oxadiazole via cyclocondensation of thiosemicarbazides have been carried out by conventional and non-conventional methods in excellent yields of product.

Synthesis of Some Novel Pyrimidine Derivatives and Investigation of their Electrochemical Behavior

  • Akbas, Esvet;Levent, Abdulkadir;Gumus, Selcuk;Sumer, Mehmet Rauf;Akyazi, Inci
    • Bulletin of the Korean Chemical Society
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    • v.31 no.12
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    • pp.3632-3638
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    • 2010
  • 2-Iminopyrimidines (1a-e) and 2-thioxopyrimidine (2) were synthesized using the Biginelli three component cyclocondensation reaction of an appropriate $\beta$-diketone, arylaldehyde, and guanidine (for 1a-e) or thiourea (for 2). The electrochemical properties of the novel systems were investigated by CV and DPV. Moreover, B3LYP/6-31G(d,p) method was applied to the present structures in order to gather some structural and physicochemical data.

An Efficient One-Pot Strategies for the Synthesis of [1,3] Oxazine Derivatives ([1,3] Oxazine 유도체 합성을 위한 효율적인 One-Pot 합성)

  • Sapkal, Suryakant B.;Shelke, Kiran F.;Shingate, Bapurao B.;Shingare, Murlidhar S.
    • Journal of the Korean Chemical Society
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    • v.54 no.4
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    • pp.437-442
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    • 2010
  • Sodium hydrogen sulphate ($NaHSO_4$), n-tetra butyl ammonium bromide (TBAB) as a phase transfer catalyst (PTC) in water, and 1-butyl-3-methyl imidazolium hydrogen sulphate [bmim]$HSO_4$ as ionic liquid (IL) has been used as a mild reaction promoter for the cyclocondensation of formalin, ${\beta}$-naphthol and aromatic amines to afford respective 2,3-dihydro-2-phenyl-1H-naphtho-[1,2-e] [1,3] oxazine derivatives. The present protocols are greener, high yielding and involved the nonchromatographic isolation procedure.

New Crown Compounds Derived from 1,2-Bis(2-hydroxybenzyl)benzene(I)

  • Woo Young Lee;Chang HePark e;Sung-Hwan Bang;Lee Sang Goo;Sim Won Bo
    • Bulletin of the Korean Chemical Society
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    • v.10 no.6
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    • pp.521-524
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    • 1989
  • By cyclocondensation of 1,2-bis(2-hydroxybenzyl)benzene with oligoethylene glycol ditosylate, new crown ethers containing 1,2-dibenzylbenzene subunit were synthesized. By oxidation of the benzylic positions of them, carbonyl-containing crowns having 1,2-dibenzoylbenzene subunit were synthesized.

Nickel Nanoparticles: An Ecofriendly and Reusable Catalyst for the Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones via Biginelli Reaction

  • Sapkal, Suryakant B.;Shelke, Kiran F.;Shingate, Bapurao B.;Shingare, Murlidhar S.
    • Bulletin of the Korean Chemical Society
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    • v.31 no.2
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    • pp.351-354
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    • 2010
  • Nickel nanoparticles (Ni NPs) appeared to exhibit the catalytic activity in one-pot cyclocondensation reaction for the preparation of 3,4-dihydropyrimidine-2(1H)-ones via Biginelli reaction from aromatic/heteroaromatic/aliphatic aldehydes, urea/thiourea and ethyl acetoacetate under microwave irradiation has been described. The UV absorbance spectra showed metallic Ni characteristics and appreciate with the particle size determined by Transmission electron microscopy (TEM). After reaction course the Ni NPs can be re-covered and reused without any apparent loss of activity.

Cyclocondensation of 2-Substituted-4-hydroxy-2H-1, 2-benzothiazine-3-carboxylic acid 1, 1-dioxides with Dicyclohexylcarbodiimide (2-치환 4-Hydroxy-2H-1, 2-benzothiazine-3-carboxylic acid 1, 1-dioxidies와 Dicyclohexylcarbodiimide의 축합환화 반응)

  • 서정진;홍유화
    • YAKHAK HOEJI
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    • v.31 no.1
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    • pp.40-41
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    • 1987
  • 4-Hydroxy-2H-1, 2-benzothiazine-3-carboxylic acid 1a was reacted with 2 equivalents of dicyclohexylcarbodiimide (DCC) to give 2-cyclohexyl-3-cyclohexylimino-4,5-dihydro-1H-imidazo [1,5-b][1,2] benzothiazine-10, 10a-dyhydro-1,10-dione 5,5-dioxide 2a and dicyclohexylurea (DCU). On the other hand 2-substituted-4-hydroxy-2H-1, 2-benzothiazine-3-carboxylic acid 1,1-dioxide 1b or c was reacted with DCC to give 2-cyclohexylimino-3-cyclohexyl-5-alkyl-4-oxo-2,5H-1,3-oxazino [5,6-c]-1,2-benzothiazine 6,6-dioxide 2b or c and DCU.

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Synthesis of 1,2,3,4-Tetrahydroquinolines Using AlCl3 in Aqua Mediated

  • Behbahani, Farahnaz K.;Ziaei, Parisa
    • Journal of the Korean Chemical Society
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    • v.58 no.1
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    • pp.44-48
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    • 2014
  • Catalytic performance of Lewis acids have been investigated in the synthesis of 1,2,3,4-tetrahydroquinolines via cyclocondensation reaction of aniline derivatives with cyclic enol ethers such as 3,4-dihydro-2H-pyran and 2,3-dihydrofuran. The catalytic activity of various of these catalysts in different solvents was compared with other classical catalysts such as KSF clay (1.5 g), $InCl_3$ (10-20 mol%), $ZrOCl_2$ (10 mol%), $Sc(OTf)_3$ (3 mol%), PANI-$InCl_3$ (10 mol%), $I_2$ (20 mol%), $InCl_3$ (5 mol%), 4-npa (25 mol%) and Cellulose-$SO_3H$ (0.03 g).