• Journal of Korean Society of Steel Construction
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• v.28 no.6
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• pp.459-465
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• 2016

In this paper, it was performed the fatigue test to examine the effect of cyclic loading for the simple T-joint. Axial force of bolt by clamping and the change of the force by applied load were measured in the joint. And the bolt force, the failure mode and the fatigue strength under cyclic loading were investigated. The parameters of the tension joint were set to be the flange thickness and the diameter of bolt to a different stiffness of the joint in response to the combination. From the fatigue test, failure mode of tensile joints under cyclic loading could be evaluated using a static ultimate load of the specific failure mode in EC3. The fatigue strength of the tension joints was considerably higher than the fatigue strength of the EC3(36) that does not consider a lever action. However, the additional axial force by lever action occurs to an increase in the axial force of the bolt it requires a careful evaluation of the fatigue strength.

• The korean journal of orthodontics
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• v.16 no.2
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• pp.53-67
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• 1986

The physical tooth movement by orthodontic force is based upon alveolar bone resorption at compression site and new bone formation at tension site of the alveolar socket. The function of the cyclic AMP is to participate not only in initial action of bone cells by mechanical forces but also in the continuous cellular response leading to bone remodelling. This experiment was performed to clarify the role of cyclic AMP in bone remodelling by mechanical force in the NORMAL group, the DIABETES group and the INSULIN TREATED group. The 72 rats were divided into the NORMAL group, the DIABETES group and the INSULIN TREATED group. The same orthodontic forces were applied to the rats of 3 groups. These rats were treated for periods of time ranging from 1 hour, 1 day, 7 days, 14 days, 21 days and 28 days. The samples of alveolar bones were obtained from compression and tension sites surrounding the tipping teeth from NORMAL, DIABETE and INSULIN TREATED rats. The samples were assayed for cyclic AMP by the cyclic AMP RIA kit. The results were as follows: 1. The cyclic AMP levels of alveolar bone in compression and tension sites showed initial decrease, then increased and .remained elevated by the time consuming. 2. The highest cyclic AMP level showed in the DIABETES group and the lowest level was in the NORMAL group. 3. The cyclic AMP levels in the INSULIN TREATED group was similar with the NORMAL group in control and tension sites, but in the compression sites it was similar with the DIABETES group.

• Ocean Systems Engineering
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• v.7 no.3
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• pp.225-246
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• 2017

Excessive dynamic-tension variations on the top-tensioned risers (TTRs) deteriorate the structural integrity and cause potential safety hazards. This phenomenon has become more remarkable in the development of deep-water fields with harsher environmental loads. The conventional prediction method of tension variations in hydro-pneumatic tensioner (HPT) has the disadvantage to underestimate the magnitude of cyclic loads. The actual excessive dynamic tension variations are larger when considering the viscous frictional fluid effects. In this paper, a suppression method of tension variations in HPT is modeled by incorporating the magneto-rheological (MR) damper and linear-force actuator. The mathematical models of the combined HPT and MR damper are developed and a force-control scheme is introduced to compensate the excessive tension variations on the riser tensioner ring. Numerical simulations and analyses are conducted to evaluate the suppression of tension variations in HPT under both regular- and irregular-wave conditions for a drilling riser of a tensioned-leg platform (TLP). The results show that significant reduction of tension variations can be achieved by introducing the proposed system. This research has provided a theoretical foundation for the HPT tension control and related structural protection.

• The korean journal of orthodontics
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• v.11 no.1
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• pp.7-15
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• 1981

Tooth movement by orthodontic force is based upon alveolar bone resorption at compression site and bone formation at tension site of tooth. The function of cyclic AMP is to participate not only in initial action of bone cells by mechanical forces but also in the continuous cellular response leading to bone remodeling. This experiment was performed to clarify the role of cyclic AMP in bone remodeling by mechanical forces. The orthodontic forces of about 80 gm and 100 gm were applied to the right canines of maxillary and mandibular bone, respectively, in cats, treated for periods of time ranging from one hour to 28 days. Alveolar bones were obtained from compression and tension sites surrounding tipping maxillary and mandibular canines as well as from contralateral control sites. The samples were extracted, boiled and homogenized, and the supernatants were assayed for cyclic AMP by a radioimmunoassay method. The results were as follows: 1. The orthodontic movement of canines was increased to the end of experimental period and the action of orthodontic forces on tooth movement was more effective in maxillary canine. 2. The cyclic AMP levels of alveolar bones in compression and tension sites initially decreased, then increased and remained elevated to the end of experiment. The differences of the cyclic AMP levels between treated sites and non-treated sites were gradually increased. 3. The cyclic AMP levels in treated sites of mandibular alveolar bone was higher than that of maxillary alveolar bone.

• Structural Engineering and Mechanics
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• v.34 no.2
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• pp.189-211
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• 2010

The behaviour of a reinforced concrete tension member is governed by the contribution of concrete between cracks, tension stiffening effect. Under highly repeated loading, this contribution is progressively reduced and the member response approximates that given by the fully cracked member. When focusing on the unloaded state, experiments show deformations larger than those of the naked reinforcement. This has been referred to as negative tension stiffening and is due to the fact that concrete carries compressive stresses along the crack spacing, even thought the tie is subjected to an external tensile force. In this paper a cycle-dependent approach is presented to reproduce the behaviour of the axially loaded tension member, paying attention to the negative tension stiffening contribution. The interaction of cyclic bond degradation and time-dependent effects of concrete is investigated. Finally, some practical diagrams are given to account for the negative tension stiffening effect in reinforced concrete elements.

• Structural Engineering and Mechanics
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• v.76 no.5
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• pp.663-674
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• 2020

In this study, partially restrained beam-column moment joints in the weak-axis direction were examined using three large-scale specimens subject to cyclic loading in order to assess the seismic resistance of the joints of low-rise steel structures and to propose joint details based on the test results. The influence of different number of bolts on the moment joints was thoroughly investigated. It was found that the flexural capacity of the joints in the direction of weak axis was highly dependent on the number of high-tension bolts. In addition, even though the flexural connections subjected to cyclic loading was perfectly designed in accordance with current design codes, severe failure mode such as block shear failure could occur at beam flange. Therefore, to prevent excessive deformation at bolt holes under cyclic loading conditions, the holes in beam flange need to have larger bearing capacity than the required tensile force. In particular, if the thickness of the connecting plate is larger than that of the beam flange, the bearing capacity of the flange should be checked for structural safety.

• Structural Engineering and Mechanics
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• v.34 no.6
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• pp.739-753
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• 2010

Pointing to the design requirement of prestressed space grid structure being the target cable force, the pretension scheme decision analysis method is studied when there's great difference between structural actual state and the analytical model. Based on recursive formulation of cable forces, the simulative recursive system for pretension process is established from the systematic viewpoint, including four kinds of parameters, i.e., system initial value (structural initial state), system input value (tensioning control force scheme), system state parameters (influence matrix of cable forces), system output value (pretension accomplishment). The system controllability depends on the system state parameters. Based on cable force observation values, the influence matrix for system state parameters can be calculated, making the system controllable. Next, the pretension scheme decision method based on cable force observation values can be formed on the basis of iterative calculation for recursive system. In this way, the tensioning control force scheme that can meet the design requirement when next cyclic supplemental tension finished is obtained. Engineering example analysis results show that the proposed method in this paper can reduce a lot of cyclic tensioning work and meanwhile the design requirement can be met.

• Transactions of Materials Processing
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• v.26 no.1
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• pp.41-47
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• 2017

Cyclic behavior of advanced high strength steel sheets was measured using an inverse-optimization approach with pre-straining and bending. First, tensile specimens were pre-strained, and three-point bending was conducted for the pre-strained specimens. By using the inverse finite element optimization, the combined isotropic-kinematic hardening parameters that minimize the error between the measured and predicted bending force-displacement curves. The measured cyclic behavior agreed well with the cyclic behavior measured by sheet tension-compression test, which confirms the validity of the measuring procedure based on inverse optimization.

• International Journal of Stem Cells
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• v.16 no.2
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• pp.202-214
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• 2023

Background and Objectives: To investigate the role of exosomes from periodontal ligament cells (PDLCs) in bone marrow mesenchymal stem cell (BMSC) migration. Methods and Results: Human PDLCs were applied cyclic tension stretching. Exosomes were extracted from cultured PDLCs by ultracentrifugation, then characterized for their size, morphology and protein markers by NTA, TEM and western blotting. The process that PKH26-labeled exosomes taken up by BMSCs was assessed by confocal microscope. BMSC migration was examined by Transwell assay. Exosomes derived from PDLCs were identified. Cyclic tension stretch application on PDLCs can enhance the migration ability of BMSCs through exosomes. The exosomal miRNA expression profiles of unstretched and stretched PDLCs were tested by miRNA microarray. Four miRNAs (miR-4633-5p, miR-30c-5p, miR-371a-3p and let-7b-3p) were upregulated and six (miR-4689, miR-8485, miR-4655-3p, miR-4672, miR-3180-5p and miR-4476) were downregulated in the exosomes after stretching. Sixteen hub proteins were found in the miRNA-mRNA network. Gene Ontology and KEGG pathway analyses demonstrated that the target genes of differentially expressed exosomal miRNAs closely related to the PI3K pathway and vesicle transmission. Conclusions: The exosomes derived from cyclic tension-stretched PDLCs can promote the migration of BMSCs. Alternation of microRNA profiles provides a basis for further research on the regulatory function of the exosomal miRNAs of PDLCs during orthodontic tooth movement.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.39
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• pp.7.1-7.9
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• 2017

Background: This study was to investigate the effect of biomechanical stimulation on osteoblast differentiation of human periosteal-derived stem cell using the newly developed bioreactor. Methods: Human periosteal-derived stem cells were harvested from the mandible during the extraction of an impacted third molar. Using the new bioreactor, 4% cyclic equibiaxial tension force (0.5 Hz) was applied for 2 and 8 h on the stem cells and cultured for 3, 7, and 14 days on the osteogenic medium. Biochemical changes of the osteoblasts after the biomechanical stimulation were investigated. No treatment group was referred to as control group. Results: Alkaline phosphatase (ALP) activity and ALP messenger RNA (mRNA) expression level were higher in the strain group than those in the control group. The osteocalcin and osteonectin mRNA expressions were higher in the strain group compared to those in the control group on days 7 and 14. The vascular endothelial growth factor (VEGF) mRNA expression was higher in the strain group in comparison to that in the control group. Concentration of alizarin red S corresponding to calcium content was higher in the strain group than in the control group. Conclusions: The study suggests that cyclic tension force could influence the osteoblast differentiation of periosteal-derived stem cells under optimal stimulation condition and the force could be applicable for tissue engineering.