• Clinical and Experimental Reproductive Medicine
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• 제26권1호
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• pp.67-73
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• 1999

The insulin-like growth factor (IGF)s are believed to one of several growth factors that play an adjunctive role in ovarian follicular development. These factors circulate bound to a family of IGF-binding protein (IGFBP)s. It is known that circulating IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue. The purposes of this study were to evaluate changes in serum IGFBPs profiles during normal ovulatory menstrual cylce and to compare serum IGFBPs profiles in periovulatory phase of between normal ovulatory menstrual cylce and controlled hyperstimulated cycle. Fasting blood samples were obtained from 15 normal healthy women throughout normal ovulatory menstural cyle and on the day of aspiration of oocyte from 10 patients undergoing ovarian hyperstimuation for in vito fertilization-embryo transfer. Serum IGFBP-1 - IGFBP-4 were measured by western ligand blot and immunoprecipitation. Serum $17{\beta}$-estradiol was determined by radioimmunoassay. Type and molecular weight of serum IGFBP did not changed during normal ovulatory menstural cycle. No significant variation in the relative proportion and level of each IGFBP was found throughout normal ovulatory menstural cyle. Also, the relative proportion and level of each IGFBP did not correlated with serum $17{\beta}$-estradiol level. There was no significant difference in the relative proportion and level of each serum IGFBP between on the day of ovulation in normal ovulatory menstrual cylce and on the day of aspiration of oocyte in controlled hyperstimulated cycle. Our data indicate that IGFBPs have regulatory functions in ovary through an paracrine and autocrine rather than endocrine mechanism during normal ovulatory menstural cycle.

• 한국해양공학회지
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• 제11권3호
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• pp.76-88
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• 1997

Constant .DELTA.K fatigue crack growth rate experiments were performed by applying an intermediate single and multiple overload for structural steel, SM45C. The purpose of the present study is to investigate the influence of multiple overloads at various stress intensity factor ranges and the effect of statistical variability of crack retardation behavior. The normalized delayed load cycle, delayed crack length and the minimum crack growth rate are increased with increasing baseline stress intensity factor range when the overload ratio and the number of overload application were constant. The crack retardation under low baseline stress intensity factor range increases by increasing the number of overload application, but the minimum crack growth rate decreases by increasing the number of overload application. A strong linear correlation exists between the minimum crack growth rate and the number of overload applications. And, it was observed that the variability in the crack growth retardation behavior are presented, the probability distribution functions of delayed load cycle, delayed crack length and crack growth life are 2-parameter Weibull. The coefficient of variation of delayed load cycle and delayed crack length for the number of 10 overload applications data are 14.8 and 9.2%, respectively.

• 미생물학회지
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• 제29권5호
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• pp.339-343
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• 1991

Heterotrophic activity, total bacteria and salinity were determined seasonally in the estuary of Naktong River over half tidal cycle. Heterotrophic activity was determined by the uptake of [U- $^{14}$ C]glucose. Heterotrophic activity fluctuated with the tides and was decreased as salinity increased. Teh great activity occurred near low ebb tide at all seasons except summer. The main environmental factor affecting hetreotrophic activity was the salinity rather than water temperature in the estuary of Naktong River. In order to estimate the effect of salt, salt was added to estuarine water. Vmax for glucose of salt-added water was 17% and 77% of original estuarine water at station 1 and 2 respectively and slight increase was observed at station 3. Respiration rate and Kt+Sn for glucose of salt-added sample increased at all 3 stations. The increase of the Kt value implies the reduced affinity of bacterial population for glucose. The effects of salinity on the heterotrophic activity were more extensive in the upper region of estuary than at the mouth.

• 환경영향평가
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• 제20권3호
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• pp.349-356
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• 2011

This research is aim to analyze of changing landscape and according to phenological cycle from image information of coastal environment obtained by multi-media were analyzed by camera and satellite image. The digital camera and satellite image were used for tidal flat vegetation monitoring during the construction of Sihwa lake. The vegetation type and phenological cycle of Sihwa tidal flat have been changed with the Sihwa lake ecosystem. The environment changes of Sihwa tidal flat area and ecological change were analyzed by field work digital camera images and satellite images. The airborne, UAV and satellite images were classified with the changed elements of coastal ecological environment and tidal flat vegetation monitoring carried out the changed area and shape of vegetation distribution with time series images.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7701-7705
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• 2015

Background: Thyroid hormones (TH) are regulated by the hypothalamic-pituitary axis, which plays an important role in cell growth, differentiation, development and other aspects of metabolism. It is believed that an active hypothalamic-pituitary axis increases the susceptibility of thyroid dysfunction during systemic chemotherapy. In order to investigate the relation between thyroid function and chemotherapy the present study was designed to investigate TH in breast cancer patients receiving at least three cycles of chemotherapy. The levels of TH were measured at the baseline and before each cycle of chemotherapy. Materials and Methods: Blood samples for estimation of TH levels were collected from 80 (pre-menopausal-40; post-menopausal-40) breast cancer patients just before they were undergoing - $1^{st}$, $2^{nd}$, $3^{rd}$ and $4^{th}$ cycle of chemotherapy. The serum was separated and $T_3$, $T_4$ and TSH levels were determined by chemiluminescence method. Results: $T_3$ and $T_4$ were found significantly decreased and TSH was found significantly increased after $1^{st}$ (p<0.001), $2^{nd}$ (p<0.0001) and $3^{rd}$ cycle of chemotherapy (p<0.0001). The variation of $T_3$ levels (decreased) and TSH levels (increased) was found more in post-menopausal (p<0.0001) women then in pre-menopausal women after $3^{rd}$ cycle of chemotherapy as compared to baseline (p<0.001). Conclusions: TH were remarkably altered after each cycle of chemotherapy leading to decline in thyroid function of breast cancer patients. Further, the results also indicated that post-menopausal women were more prone towards decline in thyroid function then pre-menopausal women. The present study proposes the monitoring of TH after each cycle of chemotherapy in breast cancer patients.

• 한국통신학회논문지
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• 제31권2A호
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• pp.86-96
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• 2006

EPON은 널리 퍼져있는 이더넷(Ethernet) 기술을 사용하고, 낮은 이더넷 장비비용과 낮은 광(fiber) 기반비용을 제공하기 때문에, 광대역 고속 가입자 망에서 점점 더 매력적인 해법으로 관심을 끌고 있다. EPON에서는 서로 다른 ONU들이 데이터를 보내기 위해서 상향 채널을 공유해야 하기 때문에 상향 트래픽을 제어하는 것이 중요하다. 본 논문에서는 높은 대역폭 사용효율을 제공하며, 서비스 클래스 별로 서로 다른 QoS를 지원하는 스케줄링 알고리즘인 HUHG(High Utilization and Hybrid Granting) 알고리즘을 제안한다. 제안된 알고리즘은 고정된 EF(Expedited Forwarding) sub-cycle의 특성을 이용하여, 다음 cycle의 EF sub-cycle을 미리 할당하여 idle time을 제거 또는 줄임으로써 높은 대역폭 사용효율을 얻을 수 있을 뿐만 아니라, EF 클래스에 대한 패킷 delay와 delay variation을 최소화 할 수 있다. 본 논문에서는 제안된 알고리즘의 효과를 확인하기 위해서 기존 연구를 바탕으로 대역폭 사용효율을 분석하고, OPNET을 통한 모의실험 결과를 통해서 성능분석을 기술한다.

• 천문학회지
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• 제44권3호
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• pp.97-108
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• 2011

The photometric light curves of the W-type W UMa eclipsing contact binary system BB Pegasi have been found to be extremely asymmetric over all the observed 63 years in all wavelengths UBVR. The light curves have been characterized by occultation primary minima. Hence, the morphology of these light curves has been studied in view of these different asymmetric degrees. The system shows a distinct O'Connell effect, as well as depth variation. A 22.96 years of stellar dark spots cycle has been determined for the system. Almost the same cycle (22.78 yr) has been found for the depth variation of MinI and MinII. We also present an analysis of mid-eclipse time measurements of BB Peg. The analysis indicates a period decrement of $5.62{\times}10^{-8}$ day/yr, which can be interpreted in terms of mass transfer at a rate of $-4.38{\times}10^{-8}M_{\odot}$/yr, from the more to the less massive component. The O - C diagram shows a damping sine wave covering two different cycles of 17.0 yr and 12.87 yr with amplitudes equal to 0.0071 and 0.0013 day, respectively. These unequal durations show a non-periodicity which may be explained as a result of magnetic activity cycling variations due to star spots. The obtained characteristics are consistent with similar chromospherically active stars, when applying the Applegate's (1992) mechanism.

• 한국전자통신학회논문지
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• 제11권1호
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• pp.87-92
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• 2016

Van der Pol 발진기는 비선형 제동 현상을 가진 비보존 발진기로서 높은 진폭에서의 에너지는 소산적이며 (dissipative)이고 낮은 진폭들에서는 생성되는 구조를 가진다. 본 논문에서는 Van Der Pol 발진기 모델에서 다른 거동을 확인하기 위하여 주기적 외력을 인가하고 여기에서 파라미터 변화에 따라 어떻게 리미트 사이클이 변화하는지에 대한 패턴을 확인하고자 한다.

• 한국자동차공학회논문집
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• 제6권4호
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• pp.47-55
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• 1998

A new ignition system concept was developed to improve ignition performance, accuracy of control and the reliability of the ignition system. The new ignition system has ho호 frequency discharge characteristics with 1.5-2.0 ms discharge duration, in place of the usual solitary longer duration event. We applied the system to a commercial engine to study its influence on the maximum combustion pressure attained during the cycle, when this peak pressure occurred, imep, variation rate of the engine speed and the flammability limit of a lean mixture. In this study, we clarified that the new ignition system had a beneficial effect of the lean mixture flammability limit. Also for a given mixture strength we found that the mew ignition system gave a higher peak cylinder pressure than in the case of the conventional ignition system.

• 한국수산과학회지
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• 제42권1호
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• pp.41-47
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• 2009

The seasonal reproductive cycle of Gomphina melanaegis collected in the coastal area of Jumunjin, between April 2006 and March 2007, was analyzed. Maturation cycle parameters such as the gonad index (GI), ovarian egg diameter, frequency of developmental stages, protein content, and RNA/DNA variation in the gonads were analyzed monthly for the 40 samples. According to the indices from histological sections, the frequency of gonad developmental stages, and the oocyte diameter, this clam has a long-term partial spawning pattern from March to October. However, GI and nucleic acid values showed that the mature stage is from March to July and that the main spawning season is August. The peak RNA and DNA contents were good indicators of sexual maturation in females and males, respectively. The variation in protein content corresponded with the RNA/DNA ratios.