• Journal of Veterinary Clinics
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• v.5 no.2
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• pp.83-86
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• 1988

Morphometric observation on the ovarian follicles of ICR strain-female mice has been conducted to investigate the effect of induced inflammation on the follicular populations. Inflammation was induced by administering 25${\mu}\ell$ of turpentine oil intraperitoneally 2 times at the interval of 3 days. Mice showing 5-day estrous cycle about 20 days after induction of inflammation are placed in experimental group. Normal follicles of 100～399$\mu\textrm{m}$ in diameter increased at estrus but those of over 400$\mu\textrm{m}$ decreased. super-ovulation increased the number of normal follicles of over 400$\mu\textrm{m}$. The number of normal follicles of over 400$\mu\textrm{m}$ 48 hours after superovulation was not significantly different between experimental and control groups. Present results indicated that the number of preovulatory follicles 48 hours after PMSG injection did not decrease in the mice which showed regular estrous cycle even after the induction of inflammation.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.4
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• pp.2752-2759
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• 1996

This paper presents crack growth analysis approach on the basis of neural networks, a branch of cognitive science to high temperature low cycle fatigue that shows strong nonlinearity in material behavior. As the number of data patterns on crack growth increase, pattern classification occurs well and two point representation scheme with gradient of crack growth curve simulates crack growth rate better than one point representation scheme. Optimal number of learning data exists and excessive number of learning data increases estimated mean error with remarkable learning time J-da/dt relation predicted by neural networks shows that test condition with unlearned data is simulated well within estimated mean error(5%).

• Geomechanics and Engineering
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• v.17 no.6
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• pp.553-564
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• 2019

This paper presents experimental results of rock-concrete bi-material discs under cyclically diametrical compression. It was found that both specimens under cyclical and static loading failed in three typical modes: shear crack, tensile crack and a combined mode of shear and wing crack. The failure modes transited gradually from the shear crack to the tensile one by increasing the interface angle between the interface and the loading direction. The cycle number and peak load increased by increasing the interface angle. The number of cycles and peak load increased with the interface groove depth and groove width, however, decreased with increase in interface groove spacing. The concrete strength can contribute more to the cycle number and peak load for specimens with a higher interface angle. Compared with the discs under static loading, the cyclically loaded discs had a lower peak load but a larger deformation. Finally, the effects of interface angle, interface asperity and concrete strength on the fatigue strength were also discussed.

• Journal of Korean Society of Transportation
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• v.19 no.1
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• pp.115-129
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• 2001

The purpose of this study is to develop a cycle-free signal timing model for minimizing delays based on Third-generation control concept using Genetic Algorithm. A special feature of this model is its ability to manage delays of turning movements on the cycle basis. The model produces a cycle-free based signal timing(cycles and green times) for each intersection to minimize delays of turning movements on the cycle basis. The performance of cycle-free signal timings was evaluated on normal (v/c = 0.7) and oversaturated (v/c=1.0) conditions. The performance measures are throughput and the number of queued vehicles at the end of green time. The result shows that the cycle free signal timing is superior to the fixed signal timing to manage traffic flows of intersections; (1) the proposed model accomplishes the basic objective of the research, producing cycle free signal timings on the cycle basis, (2) on normal conditions, cycle free signal timings produce less queued vehicles at the end of green time, and (3) on oversaturated conditions, the cycle free signal timing is superior to the fixed signal timing to manage saturated traffic flows of intersections.

• Journal of Animal Reproduction and Biotechnology
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• v.35 no.3
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• pp.232-238
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• 2020

This study used adult wistar-based rats to observe the sexual cycle as a morphological characteristic of vaginal epithelial cells by vaginal smearing, and investigated the fetal number through mating with male rats of the same strain. The target animal was a 12 to 13-week-old Wistar-based mature unlighted rat (weight 220 g to 240 g), room temperature 23 ± 2℃, 14 hours artificial lighting (05:00 to 19:00 hours), 10 hours Adapted individuals were used for rearing for at least 2 weeks under the conditions of the darkroom (19:00 to 05:00). The feed was managed for free feeding of pellet feed for animals and water. The vaginal smearing method was used for the experiments by observing the sexual cycle every morning and confirming that the normal sexual cycle of 4 or 5 days was repeated at least 2 cycles or more. As a result, the proestrus was found to have few red blood cells, the cells and nuclei were rather large and round, and many nucleated cells were identified. In the case of the estrus, the cells were large and the nuclei were not stained, and most of the keratinocytes were found. In addition, in the metestrus and diestrus, there were many white blood cells, and it was confirmed that nucleated epithelial cells and keratinocytes were significantly reduced. The pregnancy period was 21 ± 1.8 days, and the number of live births per delivery was 11.9 on average. The number of fetuses on the 8th and 10th days of pregnancy were 15.2 ± 0.4 and 15.4 ± 0.3, respectively. On the contrary, the number of fetuses on the 12th day of pregnancy was 12.9 ± 0.6, which was significantly (p < 0.05) decreased compared to the 10th day of pregnancy, and the number of fetuses was similar until delivery. As a result of investigating the change of body weight according to the birth weight and growth stage after delivery, the birth weight of female and male was 9.2 ± 2.0 g and 9.8 ± 2.5 g, respectively. After that, until the 16th day, the female and the male showed similarly moderate weight gain, and then showed a rapid weight gain until the 21st day of lactation. With reference to the results of this study, it is expected to be used as basic data for determining the mating time of rodents and controlling pregnancy and fetal number.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.6
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• pp.166-175
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• 2002

Low cycle fatigue tests are performed on the HSLA steel that be developed for a submarine material. The relation between strain energy density and numbers of cycles to failure is examined in order to predict the low cycle fatigue life of HSLA steel. The cyclic properties are determined by a least square fit techniques. The life predicted by the strain energy method is found to coincide with experimental data and results obtained from the Coffin-Manson method. Also the cyclic behavior of HSLA steel is characterized by cyclic softening with increasing number of cycle at room temperature. Especially, low cycle fatigue characteristics and microstructural changes of HSLA steel are investigated according to changing tempering temperatures. In the case of HSLA steel, the $\varepsilon$-Cu is farmed in $550^{\circ}C$ of tempering temperature and enhances the low cycle fatigue properties.

• Smart Structures and Systems
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• v.30 no.6
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• pp.571-582
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• 2022

Optimal life-cycle management is a challenging issue for deteriorating regional bridges. Due to the complexity of regional bridge structural conditions and a large number of inspection and maintenance actions, decision-makers generally choose traditional passive management strategies. They are less efficiency and cost-effectiveness. This paper suggests a deep reinforcement learning framework employing double-deep Q-networks (DDQNs) to improve the life-cycle management of deteriorating regional bridges to tackle these problems. It could produce optimal maintenance plans considering restrictions to maximize maintenance cost-effectiveness to the greatest extent possible. DDQNs method could handle the problem of the overestimation of Q-values in the Nature DQNs. This study also identifies regional bridge deterioration characteristics and the consequence of scheduled maintenance from years of inspection data. To validate the proposed method, a case study containing hundreds of bridges is used to develop optimal life-cycle management strategies. The optimization solutions recommend fewer replacement actions and prefer preventative repair actions when bridges are damaged or are expected to be damaged. By employing the optimal life-cycle regional maintenance strategies, the conditions of bridges can be controlled to a good level. Compared to the nature DQNs, DDQNs offer an optimized scheme containing fewer low-condition bridges and a more costeffective life-cycle management plan.

• Clinical and Experimental Reproductive Medicine
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• v.14 no.2
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• pp.109-118
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• 1987

Ninety-one patients with irreparable tubal disease underwent in Vitro Fertilization-Embryo Transfer (IVF-ET) in Seoul National University Hospital. Ovulation was stimulated in 104 cycles by human menopausal gonadotropin (HMG) or follicular stimulating hormone (FSH)/human chorionic gonadotropin (HCG). The patients were classified as high (>900 pg/ml), intermediate (400-900 pg/ml), or low (<400pg/ml) responder according to preovulatory $E_2$ response and four $E_2$ patterns were found. The overall pregnancy rate per cycle in this consecutive series was 11.5% (n=12). The number of preovulatory oocytes per cycle was higher significantly in intermediate and high responder group than in low responder group (P<0.01), While the number of immature oocytes per cycle significantly higher in low responder group than high and intermediate responder group (P<0.01). The pregnancy rate in each responder group was not signigicant. According to the $E_2$ pattern of response, there was no significant difference in number of the immature and preovulatory oocytes recovery per cycle. There was a apparently direct relationship between the preovulatory $E_2$ pattern and pre gnancy rate was noted.

• Development and Reproduction
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• v.16 no.3
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• pp.205-217
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• 2012

The ovarian cycle, the biological minimum size, and artificial spawning frequency by artificial spawning induction of the female hard clam, Meretrix petechialis, were investigated by histological observations and morphometric data. The ovarian cycle of this species can be classified into five successive stages: early active stage, late active stage, ripe stage, partially spawned stage, and spent/inactive stage. The spawning period was from June to September, and the main spawning occurred between July and August when the seawater temperature exceeds over $20^{\circ}C$. The biological minimum size (shell length at 50% of first sexual maturity) in females were 40.39 mm in shell length (considered to be two years of age), and all clams over 50.1 mm in shell length sexually matured. In this study, the mean number of the spawned eggs by spawning induction increased with the increase of size (shell length) classes. In case of artificial spawning induction for the clams > 40.39 mm, the number of spawned eggs from the clams of a sized class was gradually decreased with the increase of the number of the spawning frequencies (the first, second, and third spawning). In the experiments of artificial spawning induction during the spawning season, the interval of each spawning of this species was estimated to be 15-18 days (approximately 17 days).

• Parasites, Hosts and Diseases
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• v.22 no.1
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• pp.11-20
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• 1984

A number of studies on the papillae of cercariae of trematodes reported that the papillar patterns (or chaetotaxy) of cercariae might be an excellent method to attain better understanding of the digenetic trematodes (Richard, 1971 ; Short and Cartrett, 1973; Bayssade-Dufour, 1979) . The present study was aimed to determine the number, distribution pattern and structure of the sensory papillae of Metagonimus yokogawai cercariae, and to elucidate the chaetotaxy of this digenetic trematode. M. yokogawai cercariae were pipetted from a vial in which infected snails (Semisulcospira libertina) had been kept for 3 hours. The snails were collected from an endemic area of M. yokogawai, Boseong river in west-southern part of Korea. Observations of papillae were based on light microscopy of those stained with silver nitrate, and on scanning electron microscopy The results are summarized as follows: 1, All papillae observed were uniciliated. 2. Cilia in anterior tip were shorter than the others in other portions. 3. The body papillae were arranged in essentially symmetrical patterns, Total number of the papillae was 126(63 pairs) in average; anterior tip 40(20 pairs), ventral 20(10 pairs), lateral 42(21 pairs), and caudal 8(4 pairs). 4. The chaetotany of M. yokogawai cercaria was: Ci cycle ($3+3C_{I}V,{\;}2+2C_{I}L,{\;}2+3C_{I}D),{\;}C_{II}{\;}cycle(2C_{II}V,{\;}1C_{II}L,{\;}2C_{II}D),{\;}C_{lll}{\;}cycle{\;}(1+lC_{III}V,{\;}1C_{IlI}L),{\;}C_{IV}{\;}cycle{\;}(1C_{IV}V,{\;}IC_{lV}L){\;}in{\;}cephalic{\;}region:{\;}A_I(1A_{IV}V,{\;}1+2A_{I}L,{\;}1A_{I}D),{\;}A_{II}(1A_{II}V,{\;}1+3A_{II}L,{\;}1A_{II}D),{\;}A_{III}(1A_{III}V,{\;}1+1A_{III}L,{\;}1A_{III}D){\;}and{\;}A_{IV}(1A_{IV}V,{\;}2A_{IV}L)$ in antacetabular region: $1M_{I}V{\;}and{\;}2M_{I}L$ in median: $1+1P_{I}L,{\;}1P_{II}L,{\;}1P_{II}D,{\;}1P_{III}L,{\;}1P_{IV}L{\;}and{\;}1P_{IV}D$ in postacetabular region: 2-2-2-2 in caudal region.