• Title/Summary/Keyword: Cut-off values

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Validity of MAST-CLA for diagnosis of arthropod allergy using receiver operating characteristic (ROC) analysis

  • Park, Joon-Soo;Nam, Hae-Seon;Kim, Yong-Bae;Choi, Young-Jin;Lee, Sang-Han;Kim, Sung-Ho
    • Parasites, Hosts and Diseases
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    • v.45 no.3
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    • pp.239-243
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    • 2007
  • Many allergists are currently focusing on the development of new diagnostic tools, and are attempting to improve both the sensitivity and specificity. A multiple allergen simultaneous test-chemiluminescent assay (MAST-CLA) is one of the most popular diagnostic tools used in the Republic of Korea. However, there remains controversy among allergists with regard to the cut-off point for a positive result. The present study was conducted in order to determine the validity of MAST-CLA as compared with that of the skin prick test, with particular emphasis on arthropod allergens, on the basis of percentage agreement rates and k-values, and also to suggest the optimal positive cutoff points using receiver operating characteristic (ROC) curves. The study was conducted with 97 subjects (54 men, 43 women). Optimal individual cut-off points were calculated as follows; class II for Dermatophagoides farinae, class I for Dermatophagoides pteronyssinus, and trace for a cockroach mix. These findings suggest that attempting to apply optimal individual cut-off points will be a good way of improving diagnostic tests, particularly MAST-CLA.

Optical absorption of filter glasses colored by CdS, CdSe, ZnS, and ZnSe microcrystallites (CdS, CdSe, ZnS 및 ZnSe 미세결정을 이용한 filter용 유리의 광흡수특성)

  • 신용태;윤수인
    • Korean Journal of Optics and Photonics
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    • v.3 no.1
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    • pp.55-62
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    • 1992
  • The optical absorption characteristics of glasses colored by CdS. CdSe, $CdS_{1-x}Se_x$,ZnS, and ZnSe microcrystallites have been studied with emphasis on changes of the cut-off wavelength. The sharpcut filters with various cut-off wavelengths were fabricated by controlling the composition and the heat-treatment temperature. The cut-off wavelength shifts due to the different heat-treatment temperatures for CdS. CdSe, ZnS, and ZnSe doped SK-16 glasses were found to be relatively small(~30 nm). However, by treating the CdS1,Se, doped SK-16 glasses with different x values at the same heattreatment temperature, it was possible to obtain the filters with various cut-off wavelengths(~130 nm) without losing the high extinction coefficients of the filters. The filter glasses with various cut-off wavelngths(~100 nm) and high extinction coefficiencts were also produced by treating the CdSe and $CdS_{0.5}Se_{0.5}$ doped ZK-1 glasses at different temperatures.

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Experimental Study on Post-tensioned 3-Continuous Span Slabs (포스트텐션된 3연속 스팬 슬래브의 실험연구)

  • 임재형;문정호;이리형
    • Proceedings of the Korea Concrete Institute Conference
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    • 1998.10b
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    • pp.668-673
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    • 1998
  • The specimen of current study has the same type with the 3-span slabs of Burns et al used in the study by Mojtahedi/Gamble, which laid a ground for the revision of the ACI318-77 code to the ACI 318-83 code. But those specimens was failed prematurely before it reached the ultimate strength which the specimen had. The reason is that bonded reinforcements were cut off where there is no need for the flexural reinforcement. As results. the slabs failed ultimately where the reinforcements was cut off. Thus, the tendon stresses of failure may have been much smaller than the values which culd reach if the bonded reinforcements were extended beyond the theoretical cut off points. On the based on the fact mentioned above. the specimens which had the same conditions as the specimens of Burns et al were used in the current study, but in which the reinforcements were distributed in a sequence for the reinforcements not to be cut anywhere in the 3-span. As a results, it was known that the current ACI code, revised by the result of Mojtahedi/Gamble's study, overestimated the effect of span/depth ratio on the members with high span/depth ratio. Thus it was concluded that the effect of span/depth ratio on the ultimate stress of unbonded tendon regulated by the current ACI code must be reconsidered and reevaluated.

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Characteristics an Circuit Model of a Field Emission Triode

  • Nam, Jung-Hyun;Ihm, Jeong-Don;Kim, Jong-Duk;Kim, Yeo-Hwan;Park, Kyu-Man
    • Journal of Electrical Engineering and information Science
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    • v.2 no.5
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    • pp.129-133
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    • 1997
  • A circuit model for a field emission triode has been proposed. The model parameters have been extracted from he fabricated silicon tip array and verified by comparing with the results simulated by circuit simulator(SPICE). The cut-off frequency can be calculated from the parametric capacitance and the transconductance values extracted from measurements. For the field emission triode, the capacitance of 3.45fF/tip and the transconductance of 0.94nS/tip have been measured under the emission current of 4.1nA/tip. From these values, the cut-off frequency is predicted to be 43 kHz but th measured one came out to be 6 kHz. because o the parasitic capacitance components.

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Comparisons of lower extremity strength, cognition, and ankle mobility according to the 8.5seconds cut-off point for the 8-foot up-and-go test in elderly women

  • Kang, Dong-yeon;Kim, Young-mi;Lee, Kyung-soon
    • Journal of the Korean Society of Physical Medicine
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    • v.10 no.3
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    • pp.87-93
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    • 2015
  • PURPOSE: The purpose of this study was to investigate the effects of the 8.5seconds cut-off of the 8-foot up-and-go test as a predictor of falling and a good discriminator of fallers and non-fallers in women in their 60s to 80s. METHODS: The final subjects of this study were 98 elderly women from six senior centers of B metropolitan city. The 8-foot up-and-go test evaluated agility and dynamic balance. The chair-stand test measured the muscle strength for of the lower body. Ankle dorsiflexion and plantar flexion were measured to assess the ankle mobility of the subjects in this study. RESULTS: The below 8.5seconds group showed significantly low values in age and high values in chair-stand (times/30 s), plantar flexion ($^{\circ}$), and K-MMSE (score) compared to the over 8.5seconds group. This group was significantly faster compared to the over 8.5seconds group. In the below 8.5seconds group, only plantar flexion ($^{\circ}$) of all the items showed significantly higher values among those in their 60s compared to those in their 70s and 80s. CONCLUSION: The 8.5seconds cut-off on the 8-foot up-and-go test as a good discriminator and predictor of falling showed differences among fall risk factors (age, lower extremity strength, cognition, and ankle mobility) in women in their 60s to 80s without having regular exercise and a fall experience over the past ones year.

Relationship between the HVM and Cut-Off Level of Means-End Chain (수단-목적사슬(Means-End)이론의 컷오프(Cut-off) 수준과 가치 맵(Hierarchical Value Map)의 관계 분석)

  • Han, Hag-Chin;Cho, Moon-Sik;Oh, Ju-Seong;Seo, Jung-Mo
    • The Journal of the Korea Contents Association
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    • v.11 no.4
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    • pp.414-427
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    • 2011
  • The Means-end theory has successfully been applied in academics circles and is one of the qualitative methodologies, aiming at classifying into groups based on the specific values that they pursue. The more specific purposes of this study is to identify the relationship between the levels of abstraction and HVM(Hierarchical Value Map) and to identify the statistical changes in frequency activated cell and ladders among A-C-V. And lastly, to suggest the HVM according to the levels of abstraction. The subjects of this study includes the 100 hikers who joined the hiking at least once a year for 2007. The results of analysis show that as the level of abstraction goes up, the HVM itself is depicted more simple and the loss of information is also occurred. Consequently, the decision of levels of abstraction is should be made on the basis of objective validity.

Analysis on Usefulness of Non-invasive Liver Fibrosis Evaluation Method according to the Liver Disease : Focused on Hepatitis C patients (간질환 종류에 따른 비침습적 간섬유화 평가법의 유용성 분석 : C형 간염 보균자 중심으로)

  • Nam, Ji-Hee;Kim, Jung-Hoon
    • Journal of radiological science and technology
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    • v.42 no.5
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    • pp.345-350
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    • 2019
  • Liver biopsy is the gold standard for diagnosing liver fibrosis, but it is invasive and has a risk for complications. For this reason, recently, study has been actively conducted on non-invasive liver fibrosis evaluation method. But, there is no established standard for the type of diffuse liver disease. Therefore, this study was suggest the usefulness and cut-off values of Fibroscan, FIB-4, APRI and AAR of patients with hepatitis C in Korea. According to the diagnosis, 240 people in hepatitis C are classified into fatty liver, chronic hepatitis, and liver cirrhosis. The statistical analysis was performed by ANOVA to verify difference between groups. The ROC curve was analyzed to determine the usefulness and practical cut-off value. As a result, for all diseases, the AUC value for Fibroscan was 0.8 over and the APRI was 0.7 over. Cut-off value of serum based liver fibrosis markers was increased in order of fatty liver, chronic hepatitis and liver cirrhosis. If Fibroscan and serological liver fibrosis markers are applied to predict liver fibrosis, it is expected that excessive liver biopsy can be reduced.

Torsional wave dispersion in a bi-layered hollow cylinder with inhomogeneous initial stresses caused by internal and external radial pressures

  • Akbarov, Surkay D.;Bagirov, Emin T.
    • Structural Engineering and Mechanics
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    • v.77 no.5
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    • pp.571-586
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    • 2021
  • The present paper studies the influence of the inhomogeneous initial stresses in the bi-layered hollow cylinder and it is assumed that these stresses are caused by the hydrostatic pressures acting on the interior and outer free surfaces of the cylinder. The study is made by utilizing the version of the three-dimensional linearized theory of elastic waves in bodies with initial stresses for which the initial stress-strain state in bodies is determined within the scope of the classical linear theory of elasticity. For the solution to the corresponding eigenvalue problem, the discrete-analytical method is employed. Numerical results are presented and analyzed for concrete selected pairs of materials. According to these results and their analyses, it is established that, unlike homogeneous initial stresses, the influence of the inhomogeneous initial stresses on the torsional wave dispersion has not only quantitative but also qualitative character. For instance, in particular, it is established that as a result of the initial stresses caused by the hydrostatic pressure acting in the interior free surface of the cylinder, the cut-off frequency appears for the fundamental dispersive mode and the values of this frequency increase with the intensity of this pressure.

Customized BMI and waist circumference cut-off values are needed to identify metabolic syndrome among South Koreans according to their Sasang constitutional type

  • Yu, Jun-Sang;Baek, Younghwa;Hyun, Daesung;Chang, Sei-Jin
    • The Journal of Korean Medicine
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    • v.39 no.4
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    • pp.51-61
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    • 2018
  • Introduction: This study evaluated whether body mass index (BMI) and waist circumference (WC) cut-offs for predicting metabolic syndrome (MetS) were different according to Sasang constitutional type. Methods: Data were obtained from 3,117 South Koreans (20-90 years old), and MetS was defined according to the revised NCEP-ATPIII criteria. Age-adjusted BMI and WC cut-offs were calculated according to Sasang constitutional type (Soyangin [SY], Taeeumin [TE], and Soeumin [SE]), sex, and age (men: ${\geq}40$ vs. <40 years, women: ${\geq}50$ vs. <50 years). Results: The prevalences of MetS were 29.9% (<40-year-old men), 35.1% (${\geq}40$-year-old men), 14.8% (<50-year-old women), and 47.7% (${\geq}50$-year-old women). The BMI ($kg/m^2$) and WC (cm) cut-offs for <40-year-old men were 25.9 and 89.9 (SY), 25.5 and 90.5 (TE), and 21.8 and 86.2 (SE). The cut-offs for ${\geq}40$-year-old men were 23.1 and 88.9 (SY), 25.0 and 89.9 (TE), and 22.2 and 87.5 (SE). The BMI and WC cut-offs for <50-year-old women were 22.5 and 81.2 (SY), 25.1 and 83.0 (TE), and 21.5 and 79.8 (SE). The cut-offs for ${\geq}50$-year-old women were 22.2 and 80.5 (SY), and 25.2 and 89.1 (TE), and 21.9 and 80.3 (SE). Conclusions: The BMI and WC cut-offs for identifying MetS varied according to Sasang constitution type.

Comparison of Diagnostic Accuracies of Serum HE-4 Levels and 3D Power Doppler Angiography Parameters between Benign Endometrial Pathologies and Endometrial Cancer

  • Erenel, Hakan;Bese, Tugan;Sal, Veysel;Demirkiran, Fuat;Arvas, Macit
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2507-2511
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    • 2016
  • Purpose: To study the diagnostic accuracies of serum human epididymis protein 4 (HE-4) levels, virtual organ computer-aided analysis (VOCAL) parameters and endometrial volume in endometrial cancer cases. Materials and Methods: One hundred and seven patients (37 with endometrial cancer and 70 with benign endometrial pathology) were included in this study. VOCAL parameters and serum HE-4 levels were compared between the groups. Results: Area under the curve (AUC) values were 0.702, 0.658, 0.706 for vascularization index (VI), the flow index (FI) and the vascularization flow index (VFI), respectively. A cut off value of 0.568 for VI demonstrated 70% sensitivity, 72% specificity, 56% positive predictive value (PPV) and a81% negative predictive value (NPV). A cut off value of 25.8 for showed a senitivith of 70% and a specificity of 58% with aPPV of 46% and NPV of 78%, and with a cut off value of 0.12 for VFI 70%, 69%, 54% and 81%, respectively. The area under the curve for HE-4 was 0.814. A cut off value of 458 pmol/L was predictive of malignancy with 86% sensitivity and 63% specificity. Conclusions: VOCAL parameters and serum HE-4 levels were statistically significantly higher in the endometrial cancer patients. Serum HE-4 levels provided a greater sensitivity compared to power doppler angiography for predicting malignancy or benign endometrial pathology.