• Journal of the Institute of Convergence Signal Processing
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• v.4 no.1
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• pp.49-55
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• 2003

The use of digital filters in the signal process field is increasing rapidly with development of the modern industrial society. Especially, detail processors, Y/C separators, ghost removing filters, standard converters (NTSC to PAL or PAL to NTSC) and noise reducers, all of which use digital filters, tend to be used in digital video and audio processing, CATV and various communication fields. Generally, there are two different digital filters, the Rf (infinite impulse response) filter and the FIR (finite impulse response) filter in digital filter. In this paper, we have designed FIR filter which has the phase linearity and the easiness of creation. In the design of the FIR digital filter, the window function is used to alleviate the ripples caused by Gibbs Phenomenon around the cut off frequency of the band pass. But there're some problems to choose proper window function for the design destination due to its fixed values. Therefore, in this paper, we designed a modified Hanning window with new parameter which is adaptively chosen corresponding to design objectives. The digital filter was simulated to prove the validity of the model and it was compared with the Hamming, the Manning, the Blacknan and the Kaiser window function. And we have used peak side-lobe and transient characteristics as standard of judgement.

• Journal of Microbiology and Biotechnology
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• v.19 no.1
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• pp.83-92
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• 2009

Individual immunochromatographic assays (ICG) for ochratoxin A (OTA) and zearalenone (ZEA) were optimized and used in the development of a one-step simultaneous immunochromatographic assay (OS-ICG) for the rapid multianalysis of two mycotoxins in corn samples. The nitrocellulose membrane of the OS-ICG was treated with OTA-bovine serum albumin (BSA), ZEA-ovalbumin (OVA), and anti-mouse IgG in the OTA test, ZEA test, and control zones, respectively. Monoclonal antibody-gold conjugates (OTA3 MAb-gold and ZEA2C5 MAb-gold) were sprayed onto the conjugate pad. The visual detection limits were 2.5 and 5 ng/ml for OTA and ZEA, respectively, and the results were obtained within 15 min after starting the analysis. An efficient, simple, and rapid extraction method using 30% MeOH/PBS was established and validated by analyzing the corn samples spiked with OTA/ZEA mixtures (0/0, 5/10, 10/20, and $20/30\;{\mu}g/kg$). The cut-off values of the OS-ICG for the spiked corn were 5 and $10\;{\mu}g/kg$ for OTA and ZEA, respectively. Natural corn samples were analyzed by OS-ICG, direct competitive enzyme-linked immunosorbent assay (DC-ELISA), and HPLC. Results of the OS-ICG were in good agreement with those obtained by DC-ELISA and HPLC. The developed OS-ICG offers a rapid, easy-to-use, and portable analytical system and can be used as a convenient qualitative tool for the on-site simultaneous determination of OTA and ZEA in cereals, food, and agricultural products in one analytical cycle.

• Journal of the Korean Society of Physical Medicine
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• v.12 no.2
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• pp.129-136
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• 2017

PURPOSE: The purpose of this study was to compare the gait of elderly patients with and without dementia to investigate the possibility of an ambulation assessment test as a diagnostic tool for dementia. METHODS: A total of 96 subjects were included with 60 participants without dementia (control group) and 36 patients with dementia (dementia group). To compare the walking ability of the two groups, a 4-m walking test (4MWT) and Groningen Meander Walking Test (GMWT) were conducted. The GMWT is graded by amount of time in seconds and by number of oversteps outside the track. Mann-Whitney U test was used to compare the gait between the groups and the area under the curve (AUC) with Received Operating Characteristic (ROC) curve was analyzed. Statistical significance was considered at a p<.05, with a 95% confidence interval. RESULTS: There were statistically significant differences (p<.05) between the dementia group and the control group for the 4MWT, GMWTSEC, and GMWTSTEP scores. The AUC was .95 for 4MWT, .92 for GMWTSEC, and .96 for GMWTSTEP with the 95% confidence interval. The cut-off values of the ROC curve were 1.03m/s for 4MWT, 10.8 second for GMWTSEC, and 3.75 steps for GMSTEP. CONCLUSION: In our study, we investigated the utility of ambulatory assessment tools to predict dementia. The results of this study suggest that the 4MWT and the GMWT used in this study are appropriate assessment tools for dementia prediction.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.35 no.5
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• pp.529-533
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• 2002

The peptides inhibiting angiotensin converting enzyme (ACE) were isolated from the hydrolysate of manila clam (Ruditapes philippinamm) proteins prepared with thermolysin. The thermolysin hydrolysate was pretreated with membrane filter (MW cut-off 10,000) to obtain the peptide fraction with ACE inhibition. The crude peptides were applied to a Sephadex LH-20 column and eluted with $30\%$ methanol. The three active fractions (A, B and C) were collected and concentrated, and then applied to a SP-Toyopearl 650S column equilibrated with distilled water and was eluted with a linear gradient of NaCl concentration (0 to 1 M). The four active fractions (A-1, A-2, B-1 and C-1) were collected and concentrated, and then applied to a SuperQ-Toyopearl 650S column equilibrated with distilled water and was eluted with a linear gradient of NaCl concentration (0 to 1 M). The maximum inhibitory activity was observed in the fraction B-1Q showed the IC_{50} values of 0.748 $\mu$g. The abundant amino acids obtained from active fraction B-1Q were leucine, isoleucine, alanine and threonine.

• Journal of Korean Clinical Nursing Research
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• v.26 no.2
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• pp.265-273
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• 2020

Purpose: The purpose of this study was to test the predictive validity of the Fall Assessment Scale-Korean version (FAS-K) and to find the most appropriate cutoff score to screen high-risk fall groups in adult patients in general hospitals in Korea. Methods: We performed a prospective evaluation study in medical and surgical ward patients at two major general hospitals in Seoul. Data were collected from Nov. 1, 2018 to Feb. 28, 2019, nurses performed 651 observation series. The researcher measured the fall risk assessment score by applying FAS-K, MFS (Morse Fall Scale), and JHFRAT (Johns Hopkins Hospital Fall Risk Assessment tool) to the patients twice a week between 10 am and 12 noon. Data were analyzed using Pearson's corelation coefficients, and the sensitivity, specificity, predictive value, and the area under the curve (AUC) of the three tools. Results: The FAS-K was positively correlated with the MFS (r=.70, p<.001) and the JHFRAT (r=.82, p<.001). According to the receiver operating characteristics (ROC) curve analysis of the FAS-K, sensitivity, specificity, and positive and negative prediction values were 85.3%, 49.4%, 8.5%, and 98.4%, respectively, when the FAS-K score was 4. Therefore, the cut-off score of the FAS-K to identify groups with high fall risk was 4. Conclusion: The FAS-K is a valid tool for measuring fall risk in adult inpatients. In addition, the FAS-K score, 4, can be used to identify high-risk fall groups and know specific points in time to provide active interventions to prevent falls.

• Journal of Community Nutrition
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• v.2 no.2
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• pp.110-118
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• 2000

One-hundred thirty-six Chinese men and women who are members of the Malaysian Confucian Association from Kuala Lumpur city and suburbs were included in the study. They have been vegetarians for a mean period of about 6 years with the majority of them(91.2%) at lacto/ovo vegetarians. The average age of the male and female subjects in 33 and 34 years respectively. The mean BMI for the men and women are 22.5$\pm$2.4kg/$m^2$ respectively. The mean levels of serum total cholesterol, HDL-chol and LDL-chol for men are 4.27$\pm$0.77, 1,11$\pm$0.26 and 2.60$\pm$0.54mmol/L, while the corresponding values for women are 4.24$\pm$081, 1.34$\pm$0.29 and 2.41$\pm$0.28 mmol/L, All the respondents showed TC/HDL-chol levels within the normal cut-off point of <5.8mmol/L. Majority of the subjects showed normal range levels for serum retinol, carotenoids and $\alpha$-tocopherol. The mean systolic blood pressure for men and women are 122$\pm$16mmHg and 115$\pm$13mmHg, while their diastolic blood pressure are 82$\pm$7mmHg and 79$\pm$7mmHg respectively. Hypertension was found at a higher prevalence in men(17.6%) than among the women(7.1%). None of the respondents smoke cigarettes while approximately two-thirds of them carry out physical exercise at least once a week. their usual dietary intake includes frequent consumption of a wide variety of vegetables, fruits, nuts and legumes. In summary, Malaysian vegetarians have a low cardiovascular risk based on their health-oriented lifestyle.

• Journal of the Earthquake Engineering Society of Korea
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• v.24 no.5
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• pp.219-232
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• 2020

The slip-weakening model developed by Ohnaka and Yamashita is extended over the breakdown zone by equating the scaling relationships for the breakdown zone and the whole rupture area. For the extension, the study uses the relationship between rupture velocity and radiation efficiency, which was derived in the theory of linear elastic fracture mechanics, and the definition of f_max given in the specific barrier model proposed by Papageorgiou and Aki. The results clearly show that the extended scaling relationship is governed by the ratio of rupture velocity to S wave velocity, and the velocity ratio can be determined by the ratio of characteristic frequencies of a Fourier amplitude spectrum, which are corner frequency, f_c, and source-controlled cut-off frequency, f_max, or vice versa. The derived relationship is tested by using the characteristic frequencies extracted from previous studies of more than 130 shallow crustal events (focal depth less than 25 km, M_W 3.0~7.5) that occurred in Japan. Under the assumption of a dynamic similarity, the rupture velocity estimated from f_max/f_c and the modified integral timescale give quite similar scale-dependence of the rupture area to that given by Kanamori and Anderson. Also, the results for large earthquakes show good agreement to the values from a kinematic inversion in previous studies. The test results also indicate the unavailability of the spectral self-similarity proposed by Aki because of the scale-dependent rupture velocity and the rupture velocity-dependent f_max/f_c; however, the results do support the local similarity asserted by Ohnaka. It is also remarkable that the relationship between the rupture velocity and f_max/f_c is quite similar to Kolmogorov's hypothesis on a similarity in the theory of isotropic turbulence.

• Food Science and Biotechnology
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• v.18 no.3
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• pp.641-648
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• 2009

A one-step simultaneous immunchromatographic (OS-ICG) assay using colloidal gold-monoclonal antibody (gold-MAb) conjugates was developed for the rapid multianalysis of aflatoxin B1 (AFB1) and ochratoxin A (OTA) in feed samples. Visual detection limits for AFB1 and OTA were 0.5 and 2.5 ng/mL, respectively, and the results were obtained within 15 min. Matrix interference from the feed extracts was efficiently reduced by appropriate dilution with buffer. Cut-off values of the OS-ICG assay for the feed spiked with AFB1/OTA mixtures (5/5, 10/10, 25/25, 50/55, 100/100 ${\mu}g/kg$) were 10 and 50 ${\mu}g/kg$ for AFB1 and OTA. The comparative analyses of 65 feed samples by OS-ICG, enzyme-linked immunosorbent assay (ELISA), and high performance liquid chromatography (HPLC) showed good agreement. In this study, we confirmed that simultaneous analysis based on immunoassay is possible and it can be used as an on-site multianalysis of AFB1 and OTA in feed, food, and agricultural products.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.4
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• pp.97-103
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• 2017

Objectives : To identify whether pattern identification using nasal endoscopy for rhinitis can be applied as a tool for evaluating rhinitis in routine care setting, we performed a inter-rater reliability study on this pattern identification. Methods : Two Korean medicine doctors assessed 290 left/right nasal endoscopy photograph cases of rhinitis patients with pattern identification using nasal endoscopy. This pattern identification consist of four assessment items, nasal membrane color(pale/hyperemia), nasal membrane humidity(dryness/dampness), rhinorrhea(watery/yellow), and turbinate membrane edema(atrophic/edematous). Cohen's kappa statistic and Percentage agreement were used to evaluate the inter-rater reliability. Results : Inter-rater percentage agreement and Kappa coefficient for left nasal endoscopy photograph cases was from 'slight' to 'moderate'(% agreement: 40.00-67.59%/Kappa: 0.06-0.407). Only the agreement of 'rhinorrhea (watery/yellow)' item was moderate(% agreement: 67.59%/Kappa: 0.407). Inter-rater percentage agreement and Kappa coefficient for right nasal endoscopy photograph cases was also from 'slight' to 'moderate'(% agreement: 42.41-68.97%/Kappa: 0.109-0.465). Only the agreement of 'rhinorrhea(watery/yellow)' item was moderate(% agreement: 68.97%/Kappa: 0.465). Conclusions : It is necessary to resolve problems such as cut-off value setting, bipolar evaluation values(pale/hyperemia, dryness/dampness, watery/yellow, atrophic/edematous) and weighting items. Further rigorous studies that overcome the limitations of the current research are warranted.

• Journal of Preventive Medicine and Public Health
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• v.52 no.2
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• pp.101-108
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• 2019

Objectives: To objectively determine and compare the physical activity (PA) levels of adults newly diagnosed with type 2 diabetes (T2D) and adults without T2D in Vietnam using an accelerometer. Methods: A total of 120 participants with newly diagnosed T2D and 120 adults without T2D were recruited from a large hospital in Hanoi, the capital city of Vietnam. All participants wore an ActiGraph GT3X accelerometer for at least 5 days, including 1 weekend day. Freedson cut-off points were used to estimate different intensities of PA. In addition, comparisons between groups were made with respect to achieving the World Health Organization (WHO) and International Diabetes Federation (IDF) recommended PA guidelines. Results: Men with T2D had significantly lower levels of PA than men without T2D. The respective multivariable-adjusted mean values of daily step count, daily light-intensity, moderate-intensity, and moderate-to-vigorous-intensity PA were approximately 14%, 19%, and 22% lower in the men with T2D than in their non-T2D counterparts. However, women with T2D accumulated a greater number of steps per day than women without T2D. Only 59.2% of the adults with T2D met the minimum recommended level of PA (WHO and IDF), compared to 74.2% of adults without T2D (p<0.05). After adjusting for potential confounders, participants with T2D experienced 50.0% significantly lower odds of achieving PA recommendations. Conclusions: Vietnamese men with T2D were less physically active than those without T2D, and adults with T2D were less likely to meet PA guidelines. The results suggest a need for integrating PA into the self-management of this chronic condition.