• Title/Summary/Keyword: Cut-off value

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Clinical Study for Objectification of Abdominal Examination with Functional Dyspepsia - Epigastric Diagnosis using Algometer (기능성 소화불량 환자의 복진진단 객관화를 위한 임상연구 - 알고미터를 이용한 심하비경 진단 -)

  • Choi, Gyu-Ho;Rho, Gi-Hwan;Choi, Seo-Hyung
    • The Journal of Korean Medicine
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    • v.43 no.1
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    • pp.1-5
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    • 2022
  • Objectives: Using algometer, measure the pressure pain threshold (PPT) of the epigastric pain(心下痞硬) and calculate the cut-off value, and this can serve as the basis for prognostic diagnosis of functional dyspepsia so we would like to evaluate its diagnostic value. Methods: We investigated 353 patients with functional dyspepsia symptoms who admitted Gangnam Weedahm Oriental Hospital from February 1, 2021 to February 27, 2021. At the time of the patient's visit, an oriental medical doctor measured the pressure at the first pain point on the Algometer of (CV14), twice each, at 1minute intervals. The ROC (receiver operating characteristic) curve and the optimal cut-off value derived through the diagnosis of the (CV14) PPT value for epigastric pain(心下痞硬) and the gold standard of oriental medical doctor, it was evaluated through. Results: In 353 patients, the area under the ROC curve (AUC) was 0.909 (p=0). In addition, the optimal cutting value was 10.05 (kg/cm2), which was statistically significant. Additionally, the sensitivity of the Algometer's PPT measurement was 0.704 and the specificity was 0.884. As a result, if the PPT value of the Algometer exceeds 10.05 (kg/cm2) in terms of the optimal cutting value, it can be seen that epigastric pain(心下痞硬) is lost. Conclusion: Algometer's PPT value measurement can be a reliable test method for quantification of epigastric pain(心下痞硬) diagnosis and can be useful as an objective indicator.

Normal Probability Plots for Normality

  • Lee, Jea-Young;Rhee, Seong-Won
    • Communications for Statistical Applications and Methods
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    • v.6 no.3
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    • pp.687-694
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    • 1999
  • The goodness of fit statistics of normality plots are obtained using the Receiver Operating Characteristic(ROC) method. This work is intended to compare with Shapiro-Wilk W statistic. Wel will use and discuss an accuracy of the test and the best cut-off value which minimizes the sum of the type I and II error probabilities.

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Triglyceride and Glucose (TyG) Index is a Clinical Surrogate Marker for the Diagnosis of Metabolic Syndrome

  • Shin, Kyung-A
    • Biomedical Science Letters
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    • v.23 no.4
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    • pp.348-354
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    • 2017
  • TyG (triglyceride and glucose) index using triglyceride and fasting blood glucose is recommended as a useful marker for insulin resistance. The present study evaluated the usefulness of TyG index in diagnosing metabolic syndrome and suggested an optimal cut-off value. The subjects of this study were adult 4,415 adults aged 20 to 80 years who underwent health screening at J General Hospital from January 2016 to January 2017. Metabolic syndrome was based on AHA/NHLBI (American Heart Association/National Heart, Lung, and Blood Institute) criteria. TyG index correlated with metabolic syndrome risk factors including HOMA-IR. Compared with the participants in the lowest quartile of TyG index, odds ratios and 95% confidence intervals for metabolic syndrome were 8.5 (3.005~23.903), 20.0 (17.190~23.407) for those in the third, and the fourth quartile of TyG index. The optimal cut-off value of the metabolic syndrome was 8.81 for TyG index (sensitivity 86.7%, specificity 80.1%) and area under the ROC curve (AUC) was 0.894. In conclusion, TyG index is effective to identify individuals at risk for metabolic syndrome.

Diversity of the Definition of Stable Vital Sign in Trauma Patients: Results of a Nationwide Survey (외상 환자에서 안정화된 생체 징후에 대한 정의의 다양성: 전국적인 조사 결과)

  • Mun, Seong Pyo;Yoo, Young Sun
    • Journal of Trauma and Injury
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    • v.27 no.4
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    • pp.115-125
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    • 2014
  • Purpose: Stable vital signs (SVSs) are thought to be the most important criteria for successful non-operative management (NOM) of blunt spleen injury (BSI). However, a consistent definition of SVSs has been lacking. We wanted to evaluate the diversity of the definitions of SVSs by using a nationwide survey. Methods: A questionnaire regarding the definition of SVSs was sent to the trauma surgeons working at the Department of Trauma Surgery and Emergency Medicine at a level-I trauma center between October 2011 and November 2011. Data were compared using analyses of the variance, t-tests, ${\chi}^2$ tests and logistic regressions. Results: Among 201 surgeons, 198 responded (98.2%). Of these 198 responses, 45 were incomplete, so only 153 (76.1%) were analyzed. In defining the SVSs, significant diversity existed on the subjects of type of blood pressure (BP), cut-off value for hypotension, technique for measuring BP, duration of hypotension, whether or not to use the heart rate (HR) as a determinant, cut-off value of hypotension when the patient had a comorbidity or when the patient was a child. Of the 153 surgeons whose responses were analyzed, 91.5% replied that they were confused when defining SVSs. Conclusion: Confusion exists regarding how to define SVSs. Most surveyed surgeons felt that a need existed to clarify both the definition of SVSs and the use of SVSs to determine hemodynamic stability for NOM.

Enhanced Dynamic Response of SRF-PLL System for High Dynamic Performance during Voltage Disturbance

  • Choi, Hyeong-Jin;Song, Seung-Ho;Jeong, Seung-Gi;Choi, Ju-Yeop;Choy, Ick
    • Journal of Power Electronics
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    • v.11 no.3
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    • pp.369-374
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    • 2011
  • Usually, a LPF (low pass filter) is used in the feedback loop of a SRF (synchronous reference frame) - PLL (phase locked loop) system because the measured grid voltage contains harmonic distortions and sensor noises. In this paper, it is shown that the cut-off frequency of the LPF should be designed to suppress the harmonic ripples contained in the measured voltage. Also, a new design method for the loop gain of the PI-type controller in the SRF-PLL is proposed with consideration of the dynamics of the LPF. As a result, a better transient response can be obtained with the proposed design method. The LPF frequency and the PI controller gain are designed in coordination according to the steady state and dynamic performance requirements. Furthermore, in the proposed method, the controller gain and the LPF cut-off frequency are changed from their normal value to a transient value when a voltage disturbance is detected. This paper shows the feasibility and usefulness of the proposed methods through the computer simulations and experimental results.

Revaluation of Strategic Metallic Commodities in the Metallic Mines within Taebaeksan-Hwanggangri Metallogenic Belt (태백산-황강리 광화대 금속광산의 전략금속광종 재평가)

  • Lee, Jae-Ho;Heo, Chul-Ho;Chi, Se-Jung
    • Economic and Environmental Geology
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    • v.41 no.3
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    • pp.287-297
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    • 2008
  • In order to estimate the preliminary development feasibility according to the commodity, the content of 8 strategic metallic commoditites(Pb, Zn, Cu, Fe, Mo, W, Au, U) in 68 ore specimens obtained from 34 metallic mines within the Taebaegsan-Hwanggangri mineralized zone were analyzed. Analytical results are as follows. The ore specimen of Sangdong mine contained 23% copper(cut-off grade=0.7%) and those of Cheongil and Samhwanghak mines contained average 5% zinc(cut-off grade=2.0%). Especially, the detailed investigation on the above-mentioned mines is required. And, in case of molybdenum(cut-off grade=0.02%) content in Yeonhwa No. 2(0.04%) and Hong-cheon mine(0.02%), and lead(cut-off grade=0.58%) content in Wongasa mine(0.70%), and gold(cut-off grade=10ppm) content in Dongmyoung(279ppm) and Samhwanghak mine(251ppm), it is required to elastically carry out the revaluation on reopening of mines in terms of the international metal price. On the other hand, in case of uranium, iron and tungsten, it is thought that there are no mines with the development potential value in this study.

Epidemiological Cut-off Values Generated for Disc Diffusion Data from Streptococcus parauberis (Streptococcus parauberis의 디스크 확산법 결과에 대한 Epidemiological Cut-off Value의 설정)

  • Chun, Won-kyong;Lee, Yoonhang;Kim, Yoon-Jae;Roh, Heyong Jin;Kim, Ahran;Kim, Nameun;Seo, Jung-Soo;Kwon, Mun-Gyeong;Lee, Ji Hoon;Kim, Do-Hyung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.4
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    • pp.382-388
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    • 2019
  • Streptococcosis caused by Streptococcus parauberis is a very important disease in farmed olive flounder Paralichthys olivaceus. For most fish pathogens, including S. parauberis, there are no analytical criteria to distinguish antibioticsusceptible strains from antibiotic-resistant strains. In this study, epidemiological cut-off ($CO_{WT}$) values were generated to classify 75 strains of S. parauberis isolated from 1999 to 2018 as wild type (WT) and non-wild type (NWT) using disc diffusion data and normalized resistance interpretation (NRI) analysis. The susceptibility of the isolates to 16 antibiotics was evaluated using CLSI guideline M42-A. The wild-type cut-off values for amoxicillin, erythromycin, oxytetracycline, and florfenicol for S. parauberis were ${\geq}35$, 31, 28, and 27 mm, respectively. The NWT ratios of S. parauberis strains to treatment with GEN, FFC, ENR, SXT, EFT, VAN, and CHL were 17% or less, indicating that these antibiotics may be used to treat streptococcosis caused by S. parauberis. For recent S. parauberis isolates, the NWT ratios for AMX, ERY, OTC and FFC are much higher than for strains isolated from 1999-2007. The $CO_{WT}$ data from this study will assist aquatic animal disease professionals in prescribing appropriate antibiotics for the treatment of streptococcosis caused by S. parauberis, which will help reduce the misuse and abuse of antibiotics in the aquaculture sector.

Evaluation of the Usefulness of Differential Diagnosis of Thyroid Nodules using Elasticity Score and Strain Ratio in Elastogpraphy (탄성초음파에서 갑상샘 결절의 감별진단을 위한 탄성도 점수와 변형비의 유용성 평가)

  • Lee, Jin-Soo;Yang, Sung-Hee;Kim, changsoo;An, Hyun
    • Journal of the Korean Society of Radiology
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    • v.11 no.4
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    • pp.227-234
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    • 2017
  • This study evaluated the usefulness of the elasticity score and strain ratio in the differential diagnosis of benign and malignant nodules in thyroid elastography. We performed a retrospective analysis based on the results of fine needle aspiration cytology. The Chi-square test and the Mann-Whitney U test were used to analyze the difference between the five degrees of elasticity score and strain ratio according to the benign and malignant thyroid nodules. ROC curve analysis was used to determine the elasticity score and the best cut-off value of the strain ratio for the prediction of malignant nodules. There was a statistically significant difference (p=0.000) between the homogeneity of the elasticity score and the difference of the strain ratio between the benign and malignant nodule groups. On the ROC curve analysis, the elasticity score and the srain ratio for predicting benign and malignant nodules were determined as AUC 0.842, 0.700, cut-off value 3, 2.49 (p=0.001). Therefore, the elasticity score and strain ratio may be useful in the differential diagnosis of thyroid nodules.

Impact of Tumor Length on Survival for Patients with Resected Esophageal Cancer

  • Mirinezhad, Seyed Kazem;Jangjoo, Amir Ghasemi;Seyednejad, Farshad;Naseri, Ali Reza;Mohammadzadeh, Mohammad;Nasiri, Behnam;Eftekharsadat, Amir Taher;Farhang, Sara;Somi, Mohammad Hossein
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.691-694
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    • 2014
  • Background: Tumor length in patients with esophageal cancer (EC) has recently received great attention. However, its prognostic role for EC is controversial. The purpose of our study was to characterize the prognostic value of tumor length in EC patients and offer the optimum cut-off point of tumor length by reliable statistical methods. Materials and Methods: A retrospective analysis was conducted on 71 consecutive patients with EC who underwent surgery. ROC curve analysis was used to determine the optimal cut-off point for tumor length, measured with a handheld ruler after formalin fixation. Correlations between tumor length and other factors were surveyed, and overall survival (OS) rates were compared between the two groups. Potential prognostic factors were evaluated by univariate Kaplan-Meier survival analysis. A P value less than 0.05 was considered significant. Results: There were a total of 71 patients, with a male/female divide of 43/28 and a median age of 59. Characteristics were as follows: squamous/adenocarcinoma, 65/6; median tumor length, 4 (0.9-10); cut-off point for tumor length, 4cm. Univariate analysis prognostic factors were tumor length and modality of therapy. One, three and five year OS rates were 84, 43 and 43% for tumors with ${\leq}4cm$ length, whereas the rates were 75, 9 and 0% for tumors >4 cm. There was a significant association between tumor length and age, sex, weight loss, tumor site, histology, T and N scores, differentiation, stage, modality of therapy and longitudinal margin involvement. Conclusions: Future studies for modification of the EC staging system might consider tumor length too as it is an important prognostic factor. Further assessment with larger prospective datasets and practical methods (such as endoscopy) is needed to establish an optimal cut-off point for tumor length.

Development of algorithm for work intensity evaluation using excess overwork index of construction workers with real-time heart rate measurement device

  • Jae-young Park;Jung Hwan Lee;Mo-Yeol Kang;Tae-Won Jang;Hyoung-Ryoul Kim;Se-Yeong Kim;Jongin Lee
    • Annals of Occupational and Environmental Medicine
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    • v.35
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    • pp.24.1-24.15
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    • 2023
  • Background: The construction workers are vulnerable to fatigue due to high physical workload. This study aimed to investigate the relationship between overwork and heart rate in construction workers and propose a scheme to prevent overwork in advance. Methods: We measured the heart rates of construction workers at a construction site of a residential and commercial complex in Seoul from August to October 2021 and develop an index that monitors overwork in real-time. A total of 66 Korean workers participated in the study, wearing real-time heart rate monitoring equipment. The relative heart rate (RHR) was calculated using the minimum and maximum heart rates, and the maximum acceptable working time (MAWT) was estimated using RHR to calculate the workload. The overwork index (OI) was defined as the cumulative workload evaluated with the MAWT. An appropriate scenario line (PSL) was set as an index that can be compared to the OI to evaluate the degree of overwork in real-time. The excess overwork index (EOI) was evaluated in real-time during work performance using the difference between the OI and the PSL. The EOI value was used to perform receiver operating characteristic (ROC) curve analysis to find the optimal cut-off value for classification of overwork state. Results: Of the 60 participants analyzed, 28 (46.7%) were classified as the overwork group based on their RHR. ROC curve analysis showed that the EOI was a good predictor of overwork, with an area under the curve of 0.824. The optimal cut-off values ranged from 21.8% to 24.0% depending on the method used to determine the cut-off point. Conclusion: The EOI showed promising results as a predictive tool to assess overwork in real-time using heart rate monitoring and calculation through MAWT. Further research is needed to assess physical workload accurately and determine cut-off values across industries.