• Journal of the Korean Society of Environmental Restoration Technology
• /
• v.4 no.1
• /
• pp.24-31
• /
• 2001

Most of the natural calamities occurred in South Korea are due to rainfall, which are occurred during rainy season, June to September. The life-calamity reported in those seasons were over 75%, and the dead rate by the rainfall was about 98%. Especially, the disasters occurred in Pusan and Kyongsang-Namdo were highest of the whole country. The capability of landslide in this area was very high, which is included to Class 3 or Class 4 of disastrous risk grade suggested by the GIS system(Lee Su-Gon,1999). Those are based on the characteristics of topographical and meteorological data. In this study, the rainfall characteristics in Pusan were analyzed through the relationship between the cumulative rainfall and the maximum hourly rainfall. The landslide in this area depends on the elapsed time after maximum hourly rainfall intensity, and the most of landslide in Pusan recorded during within 3 hours after pick-time of rainfall intensity.

• Tuberculosis and Respiratory Diseases
• /
• v.83 no.2
• /
• pp.107-115
• /
• 2020

Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying aging biology has significantly advanced. Interestingly, many of the pivotal molecular features of aging biology are also found to contribute to the pathogenesis of chronic lung disorders such as chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis, for which advanced age is the most crucial risk factor. Thus, an enhanced understanding of how molecular features of aging biology are intertwined with the pathobiology of these aging-related lung disorders has paramount significance and may provide an opportunity for the development of novel therapeutics for these major unmet medical needs. To serve the purpose of integrating molecular understanding of aging biology with pulmonary medicine, in this review, recent findings obtained from the studies of aging-associated lung disorders are summarized and interpreted through the perspective of molecular biology of aging.

• Journal of Technology Innovation
• /
• v.12 no.3
• /
• pp.159-177
• /
• 2004

Technological innovation is one of the critical success factors determining firm's Technological innovation is one of the critical success factors determining firm's value in the knowledge based economy. The study examines whether the information release on technological innovation has information contents in the stock market. The abnormal returns and cumulative abnormal return were calculated by using Market and Risk Adjusted Return Model. The results say that the market positively reacts to the information release of technological innovation on the event date. Especially, the disclosure on technology development causes stable increase of the firm's value. It is concluded that the market reacts favorably to technological innovations.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.24 no.65
• /
• pp.31-40
• /
• 2001

We Propose an improved shovel design to minimize physical discomfort and the risk of cumulative trauma disorder at shoveling tasks. The specifications of shovels in Korean standard data were scrutinized to check if they met the anthropometric specification of Korean population in 1997. We also applied "Body Map" pictograph and self-conscious checklist to field survey to analyze the discomfort of shoveling task. Thirty male subjects whose age were ranging from 18 to 65 voluntarily participated in the experiment. The measurement results show that shoveling workers were exposed to hazards of CTD's. Especially, when workers were involved in ditch digging and construction their trunk vend more than 120 degree. In order to compare the new designed shovel and the traditional K.S shovel, an analysis of variance was performed and we obtained very strong evidence that the new designed shovel was better in reducing physical discomfort. According to the results from electromyograrn experiment the new shovel contributed to improving subjective comfort level and reducing low back muscle fatigue. For futher study, the research may be extended to determine the relationship among shovel sharpness, type, digging motion and digging force.ing force.

• Journal of Chest Surgery
• /
• v.54 no.6
• /
• pp.509-512
• /
• 2021

Extensive thoracic aortic disease involving the ascending aorta, the aortic arch, and the descending thoracic aorta may require multiple surgical and interventional managements, which impose a burden in terms of cumulative surgical trauma and the risk of interval mortality. Herein, we describe a single-stage arch and descending thoracic aorta replacement via sternotomy in a patient with multiple comorbidities presenting with an extensive thoracic aortic aneurysm.

• Journal of the Ergonomics Society of Korea
• /
• v.13 no.2
• /
• pp.57-63
• /
• 1994

This paper summarizes recent research in the use of the psychophysical method of adjustment to establish acceptable parameters for upper extremity work activities. Results from these studies show that this psychophysical approach can provide reliable guidelines based upon realistic job conditions which involve one or more risk factors for cumulative trauma. It is also shown that this method provides advantages over other psychophysical methods as well as current biomechanical and physioligical criteria.

• Genomics & Informatics
• /
• v.10 no.2
• /
• pp.99-105
• /
• 2012

Dyslipidemia, mainly characterized by high triglyceride (TG) and low high-density lipoprotein cholesterol (HDL-C) levels, is an important etiological factor in the development of cardiovascular disease (CVD). Considering the relationship between childhood obesity and CVD risk, it would be worthwhile to evaluate whether previously identified lipid-related variants in adult subjects are associated with lipid variations in a childhood obesity study (n = 482). In an association analysis for 16 genome-wide association study (GWAS)-based candidate loci, we confirmed significant associations of a genetic predisposition to lipoprotein concentrations in a childhood obesity study. Having two loci (rs10503669 at LPL and rs16940212 at LIPC) that showed the strongest association with blood levels of TG and HDL-C, we calculated a genetic risk score (GRS), representing the sum of the risk alleles. It has been observed that increasing GRS is significantly associated with decreased HDL-C (effect size, $-1.13{\pm}0.07$) compared to single nucleotide polymorphism combinations without two risk variants. In addition, a positive correlation was observed between allelic dosage score and risk allele (rs10503669 at LPL) on high TG levels (effect size, $10.89{\pm}0.84$). These two loci yielded consistent associations in our previous meta-analysis. Taken together, our findings demonstrate that the genetic architecture of circulating lipid levels (TG and HDL-C) overlap to a large extent in childhood as well as in adulthood. Post-GWAS functional characterization of these variants is further required to elucidate their pathophysiological roles and biological mechanisms.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.6 no.4
• /
• pp.24-36
• /
• 2003

This study integrates the revised universal soil loss equation(RUSLE) with a grid-based GIS method to assess the potential risk of soil erosion at the watershed scale. Data used in this study to generate the RUSLE factors include several thematic maps such as land use, topographic and soil maps, together with tabular precipitation data. Based on the RUSLE estimation for all the grids(10m cells) in the corresponding watershed, a cumulative histogram for the annual soil loss can be constructed. As the results, it shows that the 83.5% value of the annual soil loss for the watershed is less than 1ton/ha. However, the above 30% of agricultural land is defined as a medium or very high-risk area(more than 10ton/ha/yr). So it is necessary to establish soil conservation practices to reduce soil erosion based on the field observations.

• Safety and Health at Work
• /
• v.3 no.1
• /
• pp.52-57
• /
• 2012

Objectives: Lifting heavy weights involves the Valsalva manoeuvre, which leads to intraocular pressure spikes. We used data from a case-control study to further investigate the hypothesis that occupational lifting is a risk factor for retinal detachment. Methods: The study population included 48 cases (patients operated for retinal detachment) and 84 controls (outpatients attending an eye clinic). The odds ratios (OR) of idiopathic retinal detachment were estimated with a logistic regression model (adjusted for age, sex and body mass index). Three indexes were used to examine exposure to lifting; 1) maximum load lifted, 2) average weekly lifting, 3) lifelong cumulative lifting. Results: For all indexes, the most exposed subjects showed an increased risk of retinal detachment compared with the unexposed (index 1: OR 3.57, 95% confidence interval [CI] 1.21-10.48; index 2: OR 3.24, 95% CI 1.32-7.97; index 3: OR 2.23, 95% CI 1.27-8.74) and dose-response relationships were apparent. Conclusion: These results reinforce the hypothesis that heavy occupational lifting may be a relevant risk factor for retinal detachment.

• Journal of Chest Surgery
• /
• v.50 no.3
• /
• pp.171-176
• /
• 2017

Background: In elderly patients who have atrial fibrillation (AF), surgical ablation of the arrhythmia during cardiac surgery may be challenging. Despite the reported advantages of ablating AF with the Cox maze procedure (CMP), the addition of the CMP may complicate other cardiac operations. We evaluated the effect of the CMP in elderly patients concurrent with other cardiac operations. Methods: From October 2007 to December 2015, we enrolled 27 patients aged >70 years who had AF and who underwent the CMP concurrently with other cardiac operations. The mean preoperative additive European System for Cardiac Operative Risk Evaluation score was $8{\pm}11$ (high risk). Results: Only 1 hospital death occurred (4%). The Kaplan-Meier method showed a high 5-year cumulative survival rate (92%). At mean follow‐up of 51 months, 23 patients (89%) had sinus rhythm conversion. The postoperative left atrial dimensions did not significantly differ between the 8 patients who had reduction plasty for giant left atrium ($53.4{\pm}7.5cm$) and the 19 patients who did not have reduction plasty ($48.7{\pm}5.7cm$). Conclusion: In patients aged >70 years, concurrent CMP may be associated with a high rate of sinus rhythm conversion without increased surgical risk, despite the added complexity of the main cardiac procedure.