• Title/Summary/Keyword: Cryogenic fluid

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Regulation of AQP-4 Water Channel Expression in the Brain during Development and by Ischemia

  • Jung, Jin-Sup;Kim, Hae-Gyu;Bae, Hae-Rahn;Suh, Duk-Joon;Park, Hwan-Tae;Lee, Sang-Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.1 no.5
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    • pp.495-504
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    • 1997
  • Water transport is mediated by two distinct pathways, diffusional and channel-mediated water transport. The first molecular water channel was identified from human erythrocytes in 1992. Genetically-related proteins from other mammalian tissues have subsequently been identified to transport water, and the group is referred to as th "Aquaporins". Aquaporin-4 (AQP4) is most abundant in the brain, which may be involved in CSF reabsorption and osmoregulation. However, ontogeny and regulatory mechanisms of AQP4 channels have not been reported. Northern blot analysis showed that AQP4 mRNA began to be expressed in the brain just before birth and that its expression gradually increased by PN7 and then decreased at adult level. AQP4 was expressed predominantly in the ependymal cells of ventricles in newborn rats. And then its expression decreased in ependymal cells and increased gradually in other regions including supraoptic and paraventricular nuclei. AQP4 is also expressed in the subfornical organ, in which the expression level is not changed after birth. Cryogenic brain injury did not affect expression of AQP4 mRNA, while ischemic brain injury decreased it. Osmotic water permeability of AQP4 channel expressed in Xenopus oocytes was inhibited by the pretreatment of BAPTA/AM and calmidazolium, a $Ca^{2+}/Calmodulin$ kinase inhibitor, in a dose-dependent manner. These results indicate that the expression and the function of AQP4 channel are regulated by developmental processes and various pathophysiological conditions. These results will contribute to the understanding of fluid balance in the central nervous system and the osmoregulatory mechanisms of the body.

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Performance Test of 2 kW Class Reverse Brayton Refrigeration System (냉동능력 2 kW 급 역브레이튼 극저온 냉각시스템 성능시험)

  • KO, JUNSEOK;LEE, KEUN-TAE;PARK, SEONG-JE;KIM, JONGWOO;CHOO, SANGYOON;HONG, YONG-JU;IN, SEHWAN;PARK, JIHO;KIM, HYOBONG;YEOM, HANKIL
    • Transactions of the Korean hydrogen and new energy society
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    • v.31 no.5
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    • pp.429-435
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    • 2020
  • This paper describes the experimental study of reverse-Brayton refrigeration system for application to high temperature superconductivity electric devices and LNG re-liquefaction. The reverse-Brayton refrigeration cycle is designed with operating pressure of 0.5 and 1.0 MPa, cooling capacity of 2 kW at 77 K, and neon as a working fluid. The refrigeration system is developed with multi scroll compressor, turbo expander and plate heat exchanger. From experiments, the performance characteristics of used components is measured and discussed for 77-120 K of operating temperature. The developed refrigeration system shows the cooling capacity of 1.23 kW at 77 K and 1.64 kW at 110 K.

A study on the transient cooling process of a vertical-high temperature tube in an annular flow channel (환상유로에 있어서 수직고온관의 과도적 냉각과정에 관한 연구)

  • 정대인;김경근
    • Journal of Advanced Marine Engineering and Technology
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    • v.10 no.2
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    • pp.156-164
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    • 1986
  • In the case of boiling on high temperature wall, vapor film covers fully or parcially the surface. This phenomenon, film boiling or transition boiling, is very important in the surface heat treatment of metal, design of cryogenic heat exchanger and emergency cooling of nuclear reactor. Mainly supposed hydraulic-thermal accidents in nuclear reactor are LCCA (Loss of Coolant Accident) and PCM (Power-Cooling Mismatch). Recently, world-wide studies on reflooding of high temperature rod bundles after the occurrence of the above accidents focus attention on wall temperature history and required time in transient cooling process, wall superheat at rewet point, heat flux-wall superheat relationship beyond the transition boiling region, and two-phase flow state near the surface. It is considered that the further systematical study in this field will be in need in spite of the previous results in ref. (2), (3), (4). The paper is the study about the fast transient cooling process following the wall temperature excursion under the CHF (Critical Heat Flux) condition in a forced convective subcooled boiling system. The test section is a vertically arranged concentric annulus of 800 mm long and 10 mm hydraulic diameter. The inner tube, SUS 304 of 400 mm long, 8 mm I.D, and 7 mm O.D., is heated uniformly by the low voltage AC power. The wall temperature measurements were performed at the axial distance from the inlet of the heating tube, z=390 mm. 6 chromel- alumel thermocouples of 76 .mu.m were press fitted to the inner surface of the heating tube periphery. To investigate the heat transfer characteristics during the fast transient cooling process, the outer surface (fluid side) temperature and the surface heat flux are computed from the measured inner surface temperature history by means of a numerical method for inverse problems of transient heat conduction. Present cooling (boiling) curve is sufficiently compared with the previous results.

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Performance and Ignition Characteristics of a Coaxial Swirl Injector using LOX-$GCH_4$ Propellant (액체산소/기체메탄 추진제를 사용하는 동축형 스월 인젝터의 성능 및 점화특성)

  • Kim, Do-Hun;Lee, In-Chul;Kim, Jin-Kon;Koo, Ja-Ye;Park, Young-Il
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2010.11a
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    • pp.72-76
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    • 2010
  • To research and develop a high performance injector for LRE, it needs not only cold flow test, but also investigations of combustion performance, optimization of cyclogram and thermo-fluid dynamical characteristics of combustion flow field through hot-fire test. In this study, hot-fire test of LOX-CH4 coaxial swirl injector has been carried out using lab-scale hot fire test stand which can supply and control cryogenic propellant. Ignition and continuous combustion for LOX-$GCH_4$ propellant of 0.19 kg/s total mass flowrate and 2.80 O/F Ratio was achieved through cyclogram optimization. The mean combustion chamber pressure and thrust were measured as approximately 1.43 MPa and 38.7 kgf respectively.

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Investigation of Chill Down Characteristics of Liquid Oxygen Feeding System in 75 Tonf-class Liquid Rocket Engine Firing Test (75톤급 액체로켓엔진 연소시험에서의 액체산소 공급부 예냉특성 고찰)

  • Seo, Daeban;Cho, Namkyung;Han, Yeoungmin
    • Journal of the Korean Society of Propulsion Engineers
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    • v.22 no.4
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    • pp.108-116
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    • 2018
  • A firing test of the 75 tonf-class liquid rocket engine to be used as the first and second stage engines of the KSLV-II was carried out at the rocket engine test facility(RETF). Since this engine uses liquid oxygen as the oxidizer, which is a cryogenic fluid, it is essential that the chill down of the supply pipe line and engine proceed for the firing test; thus, the given inlet requirements must be met. Moreover, it is important to understand the chill down characteristics of the facility and the engine and the amount of liquid oxygen consumed in the chill down process for efficient test operation in the future. In this paper, chill down characteristics of the supply pipe and the engine were evaluated through the investigation of the chill down process of the 75 tonf-class liquid rocket engine at each stage before and after run tank pressurization. In addition, the amount of liquid oxygen consumed was also evaluated.

A Numerical Study on the Flame Arrestor for Safety Valve of Hydrogen (수소 안전밸브용 역화방지기의 성능 평가에 대한 수치해석 연구)

  • OH, SEUNG JUN;YOON, JEONG HWAN;KIM, SI POM;CHOI, JEONGJU
    • Transactions of the Korean hydrogen and new energy society
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    • v.33 no.4
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    • pp.391-399
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    • 2022
  • Hydrogen is one of the energy carriers and has high energy efficiency relative to mass. It is an eco-friendly fuel that makes only water (H2O) as a by-product after use. In order to use hydrogen conveniently and safely, development of production, storage and transfer technologies is required and attempts are being made to apply hydrogen as an energy source in various fields through the development of the technology. For transporting and storing hydrogen include high-pressure hydrogen gas storage, a type of storage technologies consist of cryogenic hydrogen liquid storage, hydrogen storage alloy, chemical storage by adsorbents and high-pressure hydrogen storage containers have been developed in a total of four stages. The biggest issue in charging high-pressure hydrogen gas which is a combustible gas is safety and the backfire prevention device is that prevents external flames from entering the tank and prevents explosion and is essential to use hydrogen safely. This study conducted a numerical analysis to analyze the performance of suppressing flame propagation of 2, 3 inch flame arrestor. As a result, it is determined that, where the flame arrestor is attached, the temperature would be lowered below the temperature of spontaneous combustion of hydrogen to suppress flame propagation.

Recent Progress in Air-Conditioning and Refrigeration Research : A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2015 (설비공학회 분야의 최근 연구 동향 : 2015년 학회지 논문에 대한 종합적 고찰)

  • Lee, Dae-Young;Kim, Sa Ryang;Kim, Hyun-Jung;Kim, Dong-Seon;Park, Jun-Seok;Ihm, Pyeong Chan
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.28 no.6
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    • pp.256-268
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    • 2016
  • This article reviews the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering during 2015. It is intended to understand the status of current research in the areas of heating, cooling, ventilation, sanitation, and indoor environments of buildings and plant facilities. Conclusions are as follows. (1) The research works on the thermal and fluid engineering were carried out in the areas of flow, heat and mass transfer, cooling and heating, and air-conditioning, the renewable energy system and the flow inside building rooms. Research issues dealing with air-conditioning machines and fire and exhausting smoke were reduced. CFD seems to be spreading to more research areas. (2) Research works on heat transfer area were carried out in the categories of heat transfer characteristics, pool boiling and condensing heat transfer and industrial heat exchangers. Researches on heat transfer characteristics included the economic analysis of GHG emission, micro channel heat exchanger, effect of rib angle on thermal performance, the airside performance of fin-and-tube heat exchangers, theoretical analysis of a rotary heat exchanger, heat exchanger in a cryogenic environment, the performance of a cross-flow-type, indirect evaporative cooler made of paper/plastic film. In the area of pool boiling and condensing, the bubble jet loop heat pipe was studied. In the area of industrial heat exchangers, researches were performed on fin-tube heat exchanger, KSTAR PFC and vacuum vessel at baking phase, the performance of small-sized dehumidification rotor, design of gas-injection port of an asymmetric scroll compressor, effect of slot discharge-angle change on exhaust efficiency of range hood system with air curtain. (3) In the field of refrigeration, various studies were carried in the categories of refrigeration cycle, alternative refrigeration/energy system, system control. In the refrigeration cycle category, a cold-climate heat pump system, $CO_2$ cascade systems, ejector cycles and a PCM-based continuous heating system were investigated. In the alternative refrigeration/energy system category, a polymer adsorption heat pump, an alcohol absorption heat pump and a desiccant-based hybrid refrigeration system were investigated. In the system control category, turbo-refrigerator capacity controls and an absorption chiller fault diagnostics were investigated. (4) In building mechanical system research fields, eighteen studies were reported for achieving effective design of the mechanical systems, and also for maximizing the energy efficiency of buildings. The topics of the studies included energy performance, HVAC system, ventilation, and renewable energies, piping in the buildings. Proposed designs, performance tests using numerical methods and experiments provide useful information and key data which can improve the energy efficiency of the buildings. (5) The field of architectural environment was mostly focused on indoor environment and building energy. The main researches of indoor environment were related to the user and location awareness technology applied dimming lighting control system, the lighting performance evaluation for light-shelves, the improvement evaluation of air quality through analysis of ventilation efficiency and the evaluation of airtightness of sliding and LS window systems. The subjects of building energy were worked on the energy saving estimation of existing buildings, the developing model to predict heating energy usage in domestic city area and the performance evaluation of cooling applied with economizer control. The studies were also performed related to the experimental measurement of weight variation and thermal conductivity in polyurethane foam, the development of flame spread prevention system for sandwich panels, the utilization of heat from waste-incineration facility in large-scale horticultural facilities.