• 한방재활의학과학회지
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• 제19권3호
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• pp.15-32
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• 2009

Objectives : The purpose of this Study was to identify the effect of Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture on pain control and nerve regeneration after crush injury in rat sciatic nerve. Methods : Neuropathic pain was induced by crush-induced model of right sciatic nerve. Animal groups were divided as follows; Group I: no treatment control group, Group II : experimental group treated with Dokhwalgisaeng-tang(Duhuoqisheng-tang), Group III : experimental group treated with Jungsongouhyul pharmacopuncture, and Group IV : experimental group treated with Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture. To evaluate pain intensity, each group was observed paw withdrawal threshold and immunoreactivity on the c-fos before and after respective treatments in five hours, first, third, and fifth day. To evaluate nerve regeneration, those were observed SFI(Sciatic Functional Index) and GAP-43(Growth Associated Protein 43) after each treatment in seventh and thirteenth day. Results : 1. Paw withdrawal threshold to the mechanical stimuli made the significant difference between group IV and the control group after five days of the experiment. 2. Paw withdrawal threshold to the thermal stimuli made the significant difference between group I and III, I and IV, II and IV. 3. In immunohistochemical response of c-fos, as time passes, the immunoreactivity of all groups was decreased gradually. Especially, group IV was observed the lowest after three days. 4. The differences of sciatic function indexes in each group were significantly between group I and III, I and IV, II and IV after 14 days, and between group I and III, I and IV, II and IV, III and IV after 21 days. 5. In immunohistochemical response of GAP-43, all groups had higher GAP-43 immunoreactivity at the 14 days from post-injury and group IV showed highest immunoreactivity. Conclusions : Based on above the results, it is proposed that Dokhwalgisaeng-tang(Duhuoqisheng-tang) and Jungsongouhyul pharmacopuncture may be helpful as a treatment in neuropathic pain and nerve regeneration in rat model.

• 대한한방내과학회지
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• 제30권2호
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• pp.375-387
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• 2009

Objective : Gyehyuldeung (GHD) has been widely used in oriental medicine for the treatments of cardiovascular and neurological disorders. Thus, its potential facilitatory activity on axonal regeneration was investigated in the rats. Methods: Sprague-Dawley rats were given crush injury at the sciatic nerve and the changes of axon growth after nerve injury on each nerve injury model were investigated with anti-NF-200 antibody, DiI, GAP-43 protein and Cdc2 protein Results : GHD-mediated enhancement of axonal regeneration after crush injury was measured in both qualitative and quantitative ways by immunofluorescence staining with anti-NF-200 antibody and retrograde tracing of fluorescence dye DiI. GAP-43 protein levels were elevated by GHD treatments in the distal injured sciatic nerve and DRG sensory neurons. The neurite outgrowth of DRG sensory neurons was facilitated by GHD treatment when co-cultured with Schwann cells and astrocytes prepared from injured sciatic nerves and injured spinal cord tissues, respectively. It was observed that Cdc2 protein was up-regulated in co-cultured Schwann cells or astrocytes and Cdc2 protein signals were co-localized to a certain extent with those of phospho-vimentin protein. Conclusions : These results suggest that GHD may play a facilitatory role in axonal regeneration by acting on the injured axons and adjacent non-neuronal cells. The current findings may be useful for the development of therapeutic targets through more specific explorations on molecular interactions between herbal components and endogenous factors.

• 한국임상수의학회지
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• 제19권3호
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• pp.316-321
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• 2002

The purpose of this study was to examine the effect of Ga-As(Gallium-Arsenide, wave length; 904 nm) infrared laser irradiation on healing of the experimentally crush injured rat sciatic nerves. The bilateral sciatic nerves of 43 adult male Sprague-Dawley rats were compressed surgically with a straight hemostat (1 mm width). The right legs of all the rats were irradiated using a 27 mW Ga-As infrared laser (laser irradiated group). The radiation procedure was administered for 3 minutes every day for 1, 3, 5, and 7 weeks in each group. Left legs were not irradiated and served as the control group. The numbers of total myelinated axon and degenerated myelin in the sciatic nerves of bilateral legs were measured and analyzed with mage analysis system in order to make a morphological analysis of the effect of the Ga-As infrared laser on injured nerves. Total number of myelinated axons was increased with time interval, especially in the 1, 3. and 5 week of irradiated group. Conversely, the number of degenerated myelin was decreased with time interval, especially in the irradiated group. The effects in the irradiated group were more pronounced than those of the control group. In conclusion, the Ga-As infrared laser irradiation is a useful adjuvant therapy to the regeneration of the peripheral nerve injury.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2015년도 추계 학술논문 발표대회
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• pp.177-178
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• 2015

Various vibration caused by construction vehicles and equipment movement, rock blasting, and crushing obstacle occurs inevitably in construction sites. In this study, we measured the impact of vibration by blasting rock at construction sites, rock crushing, concrete crushing. The measuring instrument was installed in adjacent buildings and observed that blasting vibration differs depending on the charge weight, blasting distance, and the measuring position. The observation was maintained by allowable peak particle velocity standard according to each standards and references.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.245-248
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• 1999

In our standard specification, the specific provision of steel fiber pavement concrete didn't describe yet. The purpose of this study presents criteria of recycled aggregate steel fiber pavement concrete including standard crushed stone steel fiber pavement concrete. This study examined a lot of factors which influence consistency of SFRC(Steel Fibre Reinforced Concrete) including crush stone and recycled aggregate. According to this examination, this study decided optimum S/α and W which are essential to pavement concrete mix proportion. Come to the conclusion, this study is expected to effect economically in recycling of resources and bring to affirmative result in aspect of environment.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2003년도 춘계학술대회논문집
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• pp.402-408
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• 2003

Currently tube hydroforming has many studies and applications in manufacturing industry, especially in automotive industry. But tube hydroforming was applied to the automotive component with simple shape. So the manufacturer and the researcher proposed additional processes to form the automotive component with complex shape. It is prebending and preforming. Prebending is to crush bend or rotary draw bend a tubular blank into a shape that facilitates placement into the next forming tool. Preforming is where the prebent tube is crushed into a shape that facilitates placement into the final forming tool. This paper analyzed and compared to the tube hydroforming process to using of general and preformed bending tube, also explained the importance of tube bending and preforming process. The explicit finite element program PAM-STAMP$\^$TM/ was used to simulate the tube hydroforming operations.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2001년도 가을 학술발표회 논문집
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• pp.623-628
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• 2001

The objective of this study is to find out the effect of Horizontal vibration on the compressive strength for 7 days and 28 days cured concrete specimens according to the kind of fine aggregates and the variation of vibration velocities, and times began to vibrate. Three kinds of fine aggregate(river sand, sea sand, crush sand), three types of vibration velocities(0.25, 0.5 0.1kine(cm/sec)), and four steps of times(0, 3, 6, 9 hours after concrete casting) were chosen as the experimental parameters in this study, the vibrations are applied for 30 minutes in each case. From this study, the variation with type of fine aggregate doesn't show tendency and the compressive strength decreases with increasing vibration velocity. When the vibration force time is more than 6 hour, It shows that compressive strength decreases under the condition of vibration velocity which the value is 0.5 kine and 1 kine, respectively.

• 한국전기전자재료학회논문지
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• 제27권6호
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• pp.399-406
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• 2014

Thermal batteries are used for military power sources that require robustness and long storage life such as missiles and torpedoes. $FeS_2$ powder is currently used for cathode materials because of its high specific energy density, environmental non-toxicity and low cost. However, large particle size of conventional $FeS_2$ has been deterred its possible application for higher power thermal batteries. In order to improve the power density, high energy ball milling of $FeS_2$ has been introduced to crush the micron-sized $FeS_2$. Discharge characteristics of the single cells fabricated with nano-materials and conventional $FeS_2$ powder were evaluated.

• 한국철도학회논문집
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• 제2권1호
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• pp.16-27
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• 1999

The purpose of this study is to suggest the effective analytical procedure using finite element model for the crashworthiness of motorized trailer of high speed train. The static crush of rectangular section frame is analyzed by experiment and numerical simulation. The equivalent thickness distribution of the aluminum frame ensuring the same energy absorption as the steel frame is obtained. In the analysis of end-on collision of TGV-K, deformed pattern and section forces are obtained, and the effect of crushable zone are examined. The numerical results are applied to the design of motorized trailer of Korean high speed train.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 추계학술대회논문집A
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• pp.471-476
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• 2001

The main object of this study is to develop a reliable FEM simulation technique for stability test using ABAQUS software and to clarify the effect of base profile of a steel D&I(drawn and ironed) can on the dome reversal pressure. For the can after body making simulation, two kind of stability test, dome buckle test and axial crush test are performed. The factors studied in the base profile on the dome reversal pressure are the base diameter, the rim radius, the dome shoulder radius, the dome radius and the dome depth. Within the limits before the occurrence of normal snap-through buckling of dome, the dome reversal pressure is improved by decreasing the base diameter, increasing the dome depth or increasing the dome shoulder depth.