• Title/Summary/Keyword: Cross-sensitivity

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An observational population based study on dysmenorrhea and its risk factors

  • Kotagasti, Tabassum;Rias, Nishad
    • CELLMED
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    • v.5 no.3
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    • pp.18.1-18.4
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    • 2015
  • Dysmenorrhea is the most common gynecological disorder in women of reproductive age. The prevalence of menstrual pain is relatively high and has been shown to be related to many factors like age, age at menarche, menstrual cycle regularity, parity, cigarette smoking, and dietary habits etc. This study was conducted to determine the possible link between dysmenorrhea and the factors related to it. We investigated the associated risk factors that could influence menstrual pain. This Cross Sectional Study was conducted at Dept. of OBG, NIUM, Bangalore. The study consisted of 230 women between the ages of 20 - 49 years. Included volunteers were newly married, nulliparious and parous women. The detailed reproductive history was recorded and was analyzed statistically. It was observed that there were only two factors that were influencing Dysmenorrhea namely the early age at menarche and increase parity. It was hypothesis that earlier start to reproductive life in some way decreases the sensitivity of the uterus to prostaglandin, whereas delayed menarche and postponing reproductive life increase sensitivity of the uterus to prostaglandins and cause severe menstrual pain. It is concluded that early age at menarche and high parity decrease menstrual pain.

Activation analysis of targets and lead in a lead slowing down spectrometer system

  • Lee, Yongdeok;Kim, Jeong Dong;Ahn, Seong Kyu;Park, Chang Je
    • Nuclear Engineering and Technology
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    • v.50 no.1
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    • pp.182-189
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    • 2018
  • A neutron generation system was developed to induce fissile fission in a lead slowing down spectrometer (LSDS) system. The source neutron is one of the key factors for LSDS system work. The LSDS was developed to quantify the isotopic contents of fissile materials in spent nuclear fuel and recycled fuel. The source neutron is produced at a multilayered target by the (e,${\gamma}$)(${\gamma}$,n) reaction and slowed down at the lead medium. Activation analysis of the target materials is necessary to estimate the lifetime, durability, and safety of the target system. The CINDER90 code was used for the activation analysis, and it can involve three-dimensional geometry, position dependent neutron flux, and multigroup cross-section libraries. Several sensitivity calculations for a metal target with different geometries, materials, and coolants were done to achieve a high neutron generation rate and a low activation characteristic. Based on the results of the activation analysis, tantalum was chosen as a target material due to its better activation characteristics, and helium gas was suggested as a coolant. In addition, activation in a lead medium was performed. After a distance of 55 cm from the lead surface to the neutron incidence, the neutron intensity dramatically decreased; this result indicates very low activation.

Effect of Microstructure on Dynamic Tensile Characteristics of SPRC440 Sheet (SPRC440 강판재의 미세조직 구성이 동적 인장 특성에 미치는 영향)

  • Lee, S.H.;Rhyim, Y.M.;Lee, J.H.;Kim, I.B.;Kim, Y.D.
    • Transactions of Materials Processing
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    • v.20 no.4
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    • pp.309-315
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    • 2011
  • The behavior of metallic materials at high strain rates shows different characteristics from those in quasi-static deformation. Therefore, the strain rate should be considered when simulating crash events. The objective of this paper is to evaluate the dynamic tensile characteristics of SPRC440 as a function of the volume fraction of phases. As-received SPRC440 is composed of ferrite and pearlite phases. However, ferrite and martensite phases were observed after heat treatment at $730^{\circ}C$ and $780^{\circ}C$ for 5 minutes, as expected by calculations based on the curves from dilatometry tests. High cross-head speed tensile tests were performed to acquire strain-stress curves at various strain rates ranging from 0.001 to $300\;s^{-1}$, which are typical in real vehicle crashes. It was observed that the flow stress increases with the strain rate and this trend was more pronounced in the as-received specimens consisting of ferrite and pearlite phases. It is speculated that the dislocation density in each phase has an influence on the strain rate sensitivity.

Establishment of reverse transcription polymerase chain reaction for detection of Getah virus infection in livestock

  • Lee, Seung Heon;Yang, Dong-Kun;Kim, Ha-Hyun;Choi, Sung-Suk;Cho, In-Soo
    • Korean Journal of Veterinary Research
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    • v.57 no.1
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    • pp.37-42
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    • 2017
  • Getah virus (GETV) infection causes sporadic outbreaks of mild febrile illness in horses and reproductive failure in pigs. In this study, we established a reverse transcription polymerase chain reaction (RT-PCR) method to detect GETV from suspected virus-infected samples. The reaction conditions were optimized and validated by using RNA extracted from GETV propagated in cell culture. A GETV-specific GED4 primer set was designed and used to amplify a 177 bp DNA fragment from a highly conserved region of the E1 glycoprotein gene in the GETV genome. RT-PCR performed with this primer set revealed high sensitivity and specificity. In the sensitivity test, the GED4 primer set detected GETV RNA at the level of $10^{2.0}\;TCID_{50}/mL$. In the specificity test, the GED4 primer set amplified only a single band of PCR product on the GETV RNA template, without non-specific amplification, and exhibited no cross-reactivity with other viral RNAs. These results suggest that this newly established RT-PCR method is useful for accurate identification of GETV infection in animals.

Development of a Korean Geriatric Suicidal Risk Scale (KGSRS) (한국형 노인자살위험 사정도구 개발)

  • Lee, Sang Ju;Kim, Jung Soon
    • Journal of Korean Academy of Nursing
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    • v.46 no.1
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    • pp.59-68
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    • 2016
  • Purpose: Increase in suicide rate for senior citizens which has become widespread in our society today. It is not a normal social phenomenon and is beyond the danger level. The contents of this study include Korean senior citizens' suicide related risk factors and warning signs, and the development of a simple Geriatric Suicide Risk Scale. Methods: This study is Methodological Research to verify reliability and validity of the Geriatric Suicide Risk Scale according to the tool development process suggested by Devellis (2012). Results: For predictive validity assessment, high suicide screening accuracy was showed with an Area under the ROC curve (AUC) of .93. For the optimal cutoff point of 11, sensitivity was 93.9%, and specificity, 75.7% which are excellence levels. Cross validity for assessment of generalization possibility showed the Area under the ROC curve (AUC) as .82 and in case of a cutoff point of 11, sensitivity was 73.7%, and specificity, 65.9%. Conclusion: When it comes to practical nursing, it is significant that the Korean Geriatric Suicide Risk Scale has high reliability and validity through adequate tool development and the tool assessment step to select degree of suicide risk of senior citizens. Also, it can be easily applied and does not take a long time to administer. Further, it can be used by health care personnel or the general public.

Narrow Resonant Double-Ridged Rectangular Waveguide Probe for Near-Field Scanning Microwave Microscopy

  • Kim, Byung-Mun;Son, Hyeok-Woo;Cho, Young-Ki
    • Journal of Electrical Engineering and Technology
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    • v.13 no.1
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    • pp.406-412
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    • 2018
  • In this paper, we propose a narrow resonant waveguide probe that can improve the measurement sensitivity in near-field scanning microwave microscopy. The probe consists of a metal waveguide incorporating the following two sections: a straight section at the tip of the probe whose cross-section is a double-ridged rectangle, and whose height is much smaller than the waveguide width; and a standard waveguide section. The advantage of the narrow waveguide is the same as that of the quarter-wave transformer section i.e., it achieves impedance-matching between the sample under test (SUT) and the standard waveguide. The design procedure used for the probe is presented in detail and the performance of the designed resonant probe is evaluated theoretically by using an equivalent circuit. The calculated results are compared with those obtained using the finite element method (Ansoft HFSS), and consistency between the results is demonstrated. Furthermore, the performance of the fabricated resonant probe is evaluated experimentally. At X-band frequencies, we have measured the one-dimensional scanning reflection coefficient of the SUT using the probe. The sensitivity of the proposed resonant probe is improved by more than two times as compared to a conventional waveguide cavity type probe.

Hardware implementation and error analysis of an algorithm for compensating the secondary current of iron-cored current transformers (철심 변류기의 2차 전류 보상 알고리즘의 실시간 구현 및 오차 분석)

  • 강용철;김성수;박종근;강상희;김광호
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.45 no.4
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    • pp.490-500
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    • 1996
  • The conventional method to deal with current transformer (CT) Saturation is over dimensioning of the core so that CTs can carry up to 20 times the rated current without exceeding 10% ratio correction. However, this not only reduces the sensitivity of relays as some errors may still be present in the secondary current when a severe fault occurs, but also increases the CT size. This paper presents an algorithm for compensating the distorted secondary current of iron-cored CTs under CT saturation using the magnetization (flux-current : .lambda.-i) curve and its performance is examined for fault currents encountered on a typical 345[kV] Korean transmission system, under a variety of different system and fault conditions. In addition, the results of hardware implementation of the algorithm using a TMS320C10 digital signal processor are also presented. The proposed algorithm can improve the sensitivity of relays to low level internal faults, maximize the stability of relays for external faults, and reduce the required CT core cross-section significantly. (author). refs., figs.

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NUMERICAL SIMULATION OF CONVEX AND CONCAVE TUBES WITH CONSIDERATION OF STRAIN RATE SENSITIVITY

  • Ye, B.W.;Oh, S.;Cho, Y.B.;Sin, H.C.
    • International Journal of Automotive Technology
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    • v.8 no.2
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    • pp.193-201
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    • 2007
  • The present paper deals with the application of the explicit finite element code, PAM-CRASH, to simulate the crash behavior of steel thin-walled tubes with various cross-sections subjected to axial loading. An isotropic elastic, linear strain-hardening material model was used in the finite element analysis and the strain-rate sensitivity of mild steel was modeled by using the Cowper-Symonds constitutive equation with modified coefficients. The modified coefficients were applied in numerical collapse simulations of 11 types of thin-walled polygon tubes: 7 convex polygon tubes and 4 concave polygon tubes. The results show that the thin hexagonal tube and the thick octagonal tube showed relatively good performance within the convex polygon tubes. The crush strengths of the hexagonal and octagonal tubes increased by about 20% and 25% from the crush strength of the square tube, respectively. Among the concave tubes, the I-type tube showed the best performance. Its crush strength was about 50% higher than the crush strength of the square tube.

A Study on a Sensitivity Analysis of Design Parameters for the Speed-up of Overhead Rigid Conductor System (강체전차선로 고속화를 위한 설계파라미터 민감도 분석 연구)

  • Lee, Kiwon;Cho, Yong Hyeon;Kwon, Sam-Young;Park, Young
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.2
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    • pp.453-458
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    • 2017
  • R-Bar (Overhead Rigid Conductor system) has been lately used for the speed of over 200km/h in Europe, while it has been developed and used for the max. speed of 120km/h in Korea. Because R-Bar has advantages of reduction of tunnel cross sectional area and maintenance, its development for more high-speed is urgent in Korea having many mountain area. Therefore a sensitivity analysis of design parameters for the speed-up of R-Bar has performed in this study. For the analysis, we have developed a program for the prediction of dynamic characteristics between a pantograph and R-Bar. The program was evaluated with the actual test result and a current collection performance according to the parameters such as a distance between brackets, a stiffness of bracket and of R-Bar rail was predicted with the program.

Uncertainty quantification of PWR spent fuel due to nuclear data and modeling parameters

  • Ebiwonjumi, Bamidele;Kong, Chidong;Zhang, Peng;Cherezov, Alexey;Lee, Deokjung
    • Nuclear Engineering and Technology
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    • v.53 no.3
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    • pp.715-731
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    • 2021
  • Uncertainties are calculated for pressurized water reactor (PWR) spent nuclear fuel (SNF) characteristics. The deterministic code STREAM is currently being used as an SNF analysis tool to obtain isotopic inventory, radioactivity, decay heat, neutron and gamma source strengths. The SNF analysis capability of STREAM was recently validated. However, the uncertainty analysis is yet to be conducted. To estimate the uncertainty due to nuclear data, STREAM is used to perturb nuclear cross section (XS) and resonance integral (RI) libraries produced by NJOY99. The perturbation of XS and RI involves the stochastic sampling of ENDF/B-VII.1 covariance data. To estimate the uncertainty due to modeling parameters (fuel design and irradiation history), surrogate models are built based on polynomial chaos expansion (PCE) and variance-based sensitivity indices (i.e., Sobol' indices) are employed to perform global sensitivity analysis (GSA). The calculation results indicate that uncertainty of SNF due to modeling parameters are also very important and as a result can contribute significantly to the difference of uncertainties due to nuclear data and modeling parameters. In addition, the surrogate model offers a computationally efficient approach with significantly reduced computation time, to accurately evaluate uncertainties of SNF integral characteristics.