• Title/Summary/Keyword: Cross-calibration

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Validation and Calibration of Semi-Quantitative Food Frequency Questionnaire - With Participants of the Korean Health and Genome Study - (반정량식품섭취빈도조사지의 타당성 검증 및 보정 - 지역사회 유전체 코호트 참여자를 대상으로 -)

  • Ahn, Youn-Jhin;Lee, Ji-Eun;Cho, Nam-Han;Shin, Chol;Park, Chan;Oh, Berm-Seok;Kimm, Ku-Chan
    • Korean Journal of Community Nutrition
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    • v.9 no.2
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    • pp.173-182
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    • 2004
  • We carried out a validation-calibration study of the food frequency questionnaire (FFQ) that we had previously developed for a community-based cohort of the Korean Genome and Health Study of the Korea National Genome Research Institute. We have collected a total of 254 3-day diet records (DRs) from 400 subjects, 200 each randomly selected from the two study cohorts of Ansung and Ansan. FFQ was administered at the time of cohort recruitment in 2001, and DRs were collected during a two month period from January through February of 2002. The mean age was 52.2 years. Farming for men and housewife for women were the most common occupations. The majority of the subjects had undergone 6∼12 years of education. The general characteristics including demographic and other data were not different from the total cohort subjects. Absolute levels of consumed nutrients including total energy (energy), protein, fat, carbohydrate, calcium, phosphorus, sodium, potassium, iron, retinol, carotene, vitamin A, thiamin, riboflavin, niacin and vitamin C were compared. The average of energy intake was not significantly different between the data collected by the 2 methods. However, consumptions of protein and fat were higher in data of DRs, whereas that of carbohydrate was higher in FFQ data. Significant correlation of each nutrient consumption between the data sets was observed (p < 0.05) except in the case of iron, while the average correlation coefficient between them was 0.22 ranging from 0.33 for energy to 0.11 for iron. The results of cross classification by quantile for exact classification ranged from 25.2% (carotene) to 35.0% (phosphorus), and from 64.6% (vitamin A) to 76.4% (retinol) for adjacent classification. The proportion of completely opposite classification was 8.1% in average. Calibration slope was estimated by regression and calibration parameters ranged from 0.025 for carotene to 0.423 for niacin. We conclude that the FFQ we have developed is an appropriate tool for assessing the nutrient intakes as ranking exposures in epidemiology studies in view that amounts of consumed nutrients obtained by FFQ were similar to those collected by DRs, that correlations between consumed nutrients collected by these methods were significant, and that classification results were relatively fair. The correlation coefficients, however, were lower than expected, which may be mainly due to the survey season. In fact, any short-term dietary survey cannot accurately reflect the overall dietary intakes that change heavily depending on seasons. Further studies including the analysis of chemical indices would be helpful for the studies of causal relationship between the diet and disease.

A Study of Equipment Accuracy and Test Precision in Dual Energy X-ray Absorptiometry (골밀도검사의 올바른 질 관리에 따른 임상적용과 해석 -이중 에너지 방사선 흡수법을 중심으로-)

  • Dong, Kyung-Rae;Kim, Ho-Sung;Jung, Woon-Kwan
    • Journal of radiological science and technology
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    • v.31 no.1
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    • pp.17-23
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    • 2008
  • Purpose : Because there is a difference depending on the environment as for an inspection equipment the important part of bone density scan and the precision/accuracy of a tester, the management of quality must be made systematically. The equipment failure caused by overload effect due to the aged equipment and the increase of a patient was made frequently. Thus, the replacement of equipment and additional purchases of new bonedensity equipment caused a compatibility problem in tracking patients. This study wants to know whether the clinical changes of patient's bonedensity can be accurately and precisely reflected when used it compatiblly like the existing equipment after equipment replacement and expansion. Materials and methods : Two equipments of GE Lunar Prodigy Advance(P1 and P2) and the Phantom HOLOGIC Spine Road(HSP) were used to measure equipment precision. Each device scans 20 times so that precision data was acquired from the phantom(Group 1). The precision of a tester was measured by shooting twice the same patient, every 15 members from each of the target equipment in 120 women(average age 48.78, 20-60 years old)(Group 2). In addition, the measurement of the precision of a tester and the cross-calibration data were made by scanning 20 times in each of the equipment using HSP, based on the data obtained from the management of quality using phantom(ASP) every morning (Group 3). The same patient was shot only once in one equipment alternately to make the measurement of the precision of a tester and the cross-calibration data in 120 women(average age 48.78, 20-60 years old)(Group 4). Results : It is steady equipment according to daily Q.C Data with $0.996\;g/cm^2$, change value(%CV) 0.08. The mean${\pm}$SD and a %CV price are ALP in Group 1(P1 : $1.064{\pm}0.002\;g/cm^2$, $%CV=0.190\;g/cm^2$, P2 : $1.061{\pm}0.003\;g/cm^2$, %CV=0.192). The mean${\pm}$SD and a %CV price are P1 : $1.187{\pm}0.002\;g/cm^2$, $%CV=0.164\;g/cm^2$, P2 : $1.198{\pm}0.002\;g/cm^2$, %CV=0.163 in Group 2. The average error${\pm}$2SD and %CV are P1 - (spine: $0.001{\pm}0.03\;g/cm^2$, %CV=0.94, Femur: $0.001{\pm}0.019\;g/cm^2$, %CV=0.96), P2 - (spine: $0.002{\pm}0.018\;g/cm^2$, %CV=0.55, Femur: $0.001{\pm}0.013\;g/cm^2$, %CV=0.48) in Group 3. The average error${\pm}2SD$, %CV, and r value was spine : $0.006{\pm}0.024\;g/cm^2$, %CV=0.86, r=0.995, Femur: $0{\pm}0.014\;g/cm^2$, %CV=0.54, r=0.998 in Group 4. Conclusion: Both LUNAR ASP CV% and HOLOGIC Spine Phantom are included in the normal range of error of ${\pm}2%$ defined in ISCD. BMD measurement keeps a relatively constant value, so showing excellent repeatability. The Phantom has homogeneous characteristics, but it has limitations to reflect the clinical part including variations in patient's body weight or body fat. As a result, it is believed that quality control using Phantom will be useful to check mis-calibration of the equipment used. A value measured a patient two times with one equipment, and that of double-crossed two equipment are all included within 2SD Value in the Bland - Altman Graph compared results of Group 3 with Group 4. The r value of 0.99 or higher in Linear regression analysis(Regression Analysis) indicated high precision and correlation. Therefore, it revealed that two compatible equipment did not affect in tracking the patients. Regular testing equipment and capabilities of a tester, then appropriate calibration will have to be achieved in order to calculate confidential BMD.

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VALIDATION OF ON-LINE MONITORING TECHNIQUES TO NUCLEAR PLANT DATA

  • Garvey, Jamie;Garvey, Dustin;Seibert, Rebecca;Hines, J. Wesley
    • Nuclear Engineering and Technology
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    • v.39 no.2
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    • pp.133-142
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    • 2007
  • The Electric Power Research Institute (EPRI) demonstrated a method for monitoring the performance of instrument channels in Topical Report (TR) 104965, 'On-Line Monitoring of Instrument Channel Performance.' This paper presents the results of several models originally developed by EPRI to monitor three nuclear plant sensor sets: Pressurizer Level, Reactor Protection System (RPS) Loop A, and Reactor Coolant System (RCS) Loop A Steam Generator (SG) Level. The sensor sets investigated include one redundant sensor model and two non-redundant sensor models. Each model employs an Auto-Associative Kernel Regression (AAKR) model architecture to predict correct sensor behavior. Performance of each of the developed models is evaluated using four metrics: accuracy, auto-sensitivity, cross-sensitivity, and newly developed Error Uncertainty Limit Monitoring (EULM) detectability. The uncertainty estimate for each model is also calculated through two methods: analytic formulas and Monte Carlo estimation. The uncertainty estimates are verified by calculating confidence interval coverages to assure that 95% of the measured data fall within the confidence intervals. The model performance evaluation identified the Pressurizer Level model as acceptable for on-line monitoring (OLM) implementation. The other two models, RPS Loop A and RCS Loop A SG Level, highlight two common problems that occur in model development and evaluation, namely faulty data and poor signal selection

Quantitative In-line NIR measurements of papers

  • Schmidt, Angela;Weiler, Helmut
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1285-1285
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    • 2001
  • For NIR measurements of papers normally diffuse reflectance accessories are used which can provide a large sampling area. The in-line process control FT-NIR spectrometer MATRIX-E enables the contactless measurement of paper samples of low silicone coat weights on label-stocks in a paper converting factory. For this study concentrations of silicone between 0 and 2 g/$m^2$ on various paper substrates were included in a quantitative method. The aim was to achieve an absolute value for the deviation from the target value of 1 g/$m^2$ during continuous movement of the paper with velocities around 400 numinute. Influences from the uncoated paper type due to supplier, color, opacity, area densities, pre-coating as well as different compounds of the agent silicone were investigated and it was found that all these papers can be represented in one PLS-model. Especially the fact that silicone as an element is present in clay coated papers is of no consequence to the measurements with MATRIX-E. Moreover during in-line installations the variation of the moisture contents in the moving paper due to variable machine velocities as well as the reflecting material of the cylinder have to be considered. It is shown that the result of the in-line calibration has the same prediction ability compared to lab scale results(Root Mean Square Error of Cross-Validation RMSECV = 0.034 g/$m^2$).

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QUANTITATIVE IN-LINE NIR MEASUREMENTS OF PAPERS

  • Schmidt, Angela;Weiler, Helmut
    • Proceedings of the Korean Society of Near Infrared Spectroscopy Conference
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    • 2001.06a
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    • pp.1193-1193
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    • 2001
  • For NIR measurements of papers normally diffuse reflectance accessories are used which can provide a large sampling area. The in-line process control FT-NIR spectrometer MATRIX-E enables the contactless measurement of paper samples of low silicone coat weights on label-stocks in a paper converting factory. For this study concentrations of silicone between 0 and 2 g/㎡ on various paper substrates were included in a quantitative method. The aim was to achieve an absolute value for the deviation from the target value of 1 g/㎡ during continuous movement of the paper with velocities around 400 m/minute. Influences from the uncoated paper type due to supplier, color, opacity, area densities, pre-coating as well as different compounds of the agent silicone were investigated and it was found that all these papers can be represented in one PLS-model. Especially the fact that silicone as an element is present in clay coated papers is of no consequence to the measurements with MATRIX-E. Moreover during in-line installations the variation of the moisture contents in the moving paper due to variable machine velocities as well as the reflecting material of the cylinder have to be considered. It is shown that the result of the in-line calibration has the same prediction ability compared to lab scale results (Root Mean Square Error of Cross-Validation RMSECV = 0.034 g/㎡).

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Temperature Field Measurement of Non-Isothermal Jet Flow Using LIF Technique (레이저형광여기(LIF)를 이용한 비등온 제트유동의 온도장 측정)

  • Yoon, Jong-Hwan;Lee, Sang-Joon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.24 no.10
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    • pp.1399-1408
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    • 2000
  • A 2-dimensional temperature field measurement technique using PLIF (Planar Laser Induced Fluorescence) was developed and it was applied to an axisymmetric buoyant jet. Rhodamine B was used as a fluorescent dye. Laser light sheet illuminated a two-dimensional cross section of the jet. The intensity variations of LIF signal from Rhodamine B molecules scattered by the laser light were captured with an optical filter and a CCD camera. The spatial variations of temperature field of buoyant jet were derived using the calibration data between the LIF signal and real temperature. The measured results show that the turbulent jet is more efficient in mixing compared to the transition and laminar jet flows. As the initial flow condition varies from laminar to turbulent flow, the entrainment from ambient fluid increases and temperature decay along the jet center axis becomes larger. In addition to the mean temperature field, the spatial distributions of temperature fluctuations were measured by the PLIF technique and the result shows the shear layer development from the jet nozzle exit.

Effect of normal load on the crack propagation from pre-existing joints using Particle Flow Code (PFC)

  • Haeri, Hadi;Sarfarazi, Vahab;Zhu, Zheming
    • Computers and Concrete
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    • v.19 no.1
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    • pp.99-110
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    • 2017
  • In this paper, the effect of normal load on the failure mechanism of echelon joint has been studied using PFC2D. In the first step, calibration of PFC was undertaken with respect to the data obtained from experimental laboratory tests. Then, six different models consisting various echelon joint were prepared and tested under two low and high normal loads. Furthermore, validation of the simulated models were cross checked with the results of direct shear tests performed on non-persistent jointed physical models. The simulations demonstrated that failure patterns were mostly influenced by normal loading, while the shear strength was linked to failure mechanism. When ligament angle is less than $90^{\circ}$, the stable crack growth length is increased by increasing the normal loading. In this condition, fish eyes failure pattern occur in rock bridge. With higher ligament angles, the rock bridge was broken under high normal loading. Applying higher normal loading increases the number of fracture sets while dilation angle and mean orientations of fracture sets with respect to ligament direction will be decreased.

In Situ Estimation of the Constituents of Green Soybean (Edamame) Pod using Near-Infrared Transmission Spectroscopy

  • Suzuki, Michiru;Katahira, Mitsuhiko;Natsuga, Motoyasu
    • Journal of Biosystems Engineering
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    • v.39 no.4
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    • pp.352-356
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    • 2014
  • Purpose: We estimated the dietary qualities of green soybean (edamame) by using a specialized NIR transmission spectrometer to determine the constitutive properties of the soybean, such as the sucrose content and ninhydrine reaction quantity (NRQ; defined by the ninhydrine reaction, which has a high positive correlation with the total free amino acids), with the purpose of establishing a quality assurance system. Methods: We used a newly developed spectrometer probe that enables in situ estimation of the constituents of the soybean. Results: The calibration results obtained using a wavelength range of 760-960 nm were characterized by $R^2$ = 0.57 and standard error of cross-validation (SECV) of 0.78% for sucrose, and $R^2$ = 0.59 and SECV = 0.35% for NRQ. Conclusions: These results are inferior to those of our previous study obtained using a specialized bench-type transmission spectrometer. The poorer results are attributed to several possible reasons, including the effect of direct sunlight and the unstable sample presentation. We plan to conduct further study using improved optical layout and sample presentation.

Structural performance of cold-formed steel column bases with bolted moment connections

  • Chung, K.F.;Yu, W.K.;Wang, A.J.
    • Steel and Composite Structures
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    • v.5 no.4
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    • pp.325-340
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    • 2005
  • This paper presents a thorough investigation into the structural performance of cold-formed steel column bases using double lipped C sections with bolted moment connections. A total of four column base tests with different connection configurations were carried out, and it was found that section failure under combined bending and shear was always critical. Moreover, the proposed column bases were demonstrated to be structurally efficient attaining moment resistances close to those of the connected sections. In order to examine the structural behaviour of the column base connections, a finite element model was established using shell and spring elements to model the sections and the bolted fastenings respectively. Both material and geometrical non-linearities were incorporated, and comparison between the test and the numerical results was presented in details. The design rules originally developed for bolted moment connections between lapped Z sections were adopted and re-formulated for the design of column base connections after careful calibration against the test data. Comparison on co-existing moments and shear forces at the critical cross-sections of the column bases was fully presented. It was shown that the proposed design and analysis method was structurally adequate to predict the failure loads under combined bending and shear for column bases with similar connection configurations.

Structural performance of cold-formed steel column bases with bolted moment connections

  • Chung, K.F.;Yu, W.K.;Wang, A.J.
    • Steel and Composite Structures
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    • v.5 no.4
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    • pp.289-304
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    • 2005
  • This paper presents a thorough investigation into the structural performance of cold-formed steel column bases using double lipped C sections with bolted moment connections. A total of four column base tests with different connection configurations were carried out, and it was found that section failure under combined bending and shear was always critical. Moreover, the proposed column bases were demonstrated to be structurally efficient attaining moment resistances close to those of the connected sections. In order to examine the structural behaviour of the column base connections, a finite element model was established using shell and spring elements to model the sections and the bolted fastenings respectively. Both material and geometrical non-linearities were incorporated, and comparison between the test and the numerical results was presented in details. The design rules originally developed for bolted moment connections between lapped Z sections were adopted and re-formulated for the design of column base connections after careful calibration against the test data. Comparison on co-existing moments and shear forces at the critical cross-sections of the column bases was fully presented. It was shown that the proposed design and analysis method was structurally adequate to predict the failure loads under combined bending and shear for column bases with similar connection configurations.