• Title/Summary/Keyword: Critical Factor of Using

Search Result 1,123, Processing Time 0.036 seconds

The Expression of Galectin-3, a Beta-Galactoside Binding Protein, in Dendritic Cells

  • Kim, Mi-Hyoung;Joo, Hong-Gu
    • IMMUNE NETWORK
    • /
    • v.5 no.2
    • /
    • pp.105-109
    • /
    • 2005
  • Background: Dendritic cells (DCs) are the most potent APCs (antigen-presenting cells) and playa critical role in immune responses. Galectin-3 is a biological lectin with a beta-galactoside binding affinity. Recently, proteomic analysis revealed the presence of galectin-3 in the exosome of mature DCs. However, the expression and function of galectin-3 in DCs remains unclear yet. Methods: We used bone marrow-derived DCs of mouse and showed the expression of galectin-3 in DCs by using flow cytometry analysis and Western blot analysis. Results: Galectin-3 was determined as single band of 35 kDa in Western blot analysis. Flow cytometry analysis showed the major growth factor for DCs, granulocyte-macrophage colony stimulating factor (GM-CSF) and maturing agents, anti-CD40 monoclonal antibody (mAb) and lipopolysaccharide (LPS) consistently increased the intracellular expression of galectin-3 in DCs compared to medium alone. In addition, DCs treated with maturing agents did marginally express galectin-3 on their surface. Conclusion: This study suggests that galectin-3 in DCs may be regulated by critical factors for DC function.

Synthesis of Epoxidized Soybean Oil (ESO) and its Blends with Tetrafunctional Epoxy Resins (Epoxidized soybean oil(ESO)의 합성 및 4 관능성 에폭시 수지/ESO 블렌드 시스템의 물성)

  • Lee, Jae-Rock;Jin, Fan-Long;Park, Soo-Jin
    • Proceedings of the Korean Society For Composite Materials Conference
    • /
    • 2003.04a
    • /
    • pp.180-183
    • /
    • 2003
  • In this work. a potential inexpensive epoxy resin. epoxidized soybean oil (ESO) was synthesized and applied as a toughening agent for 4.4'-tetradiglycidyl diaminodiphenyl methane (TGDDM). The chemical structure of ESO was characterized by FT-IR, $^1H NMR, and ^{13}C NMR$ spectroscopy. The curing behaviors. thermal stabilities. fracture toughness. and flexural strength of TGDDM/ESO blend systems were investigated by using the dynamic DSC. thermogravimetric analysis (TGA). and flexural tests. The thermal stabilities of TGDDM/ESO blend systems were decreased with increasing ESO contents. whereas the critical stress intensity factor ($K_{IC}$) and flexural strength ($\sigma_f$) were increased with ESO contents up to 10 wt% ESO.

  • PDF

Path-Analysis for Minimize a Conflict on Urban Regeneration Project (도시재생사업의 갈등 최소화를 위한 경로분석)

  • Kim, Ka-Ram;Yu, Jung-Ho
    • Proceedings of the Korean Institute of Building Construction Conference
    • /
    • 2011.05a
    • /
    • pp.181-184
    • /
    • 2011
  • The earlier studies which are related to conflict management for urban regeneration project were based on limited case-studies on a specific phase. In addition, those studies did not considered a multidisciplinary approach for critical factor of conflict occurrence. In this reason, to establish a practical management or a policy is limited. In this paper, 'Good communication and information sharing' and 'Cooperativeness of stakeholders on project' are defined by critical factors for minimization of conflict between stakeholders. Furthermore we analysis the influence of those factors to minimization of conflict using path-analysis. This paper contributes to increase the efficiency of conflict management through understanding influence of each factors.

  • PDF

Minimum Velocity of Sewerage Pipes (하수관거의 최저유속)

  • Yu, Dong-Hun;Lee, Jeong-Yeong
    • Journal of Korea Water Resources Association
    • /
    • v.32 no.4
    • /
    • pp.469-478
    • /
    • 1999
  • Explicit equations of minimum velocity, energy slope and pipe diameter are developed to ensure the cleaning of sewerage pipes. The equations of power form are employed for the estimation of critical shear stress of sediment particles and the friction factor of commercial pipes. They are all based on the existing laboratory data. Several cases are tested to check the values suggested in the manual, using the equations developed in the present study.

  • PDF

The Unit Commitment Using the Sensitivity Factor of Security Constrained Optimal Power Flow (SC-OPF의 민감도 계수를 이용한 발전기 기동.정지계획)

  • Kim, Kwang-Mo;Chung, Koo-Hyung;Han, Seok-Man;Kim, Bal-Ho
    • Proceedings of the KIEE Conference
    • /
    • 2006.07a
    • /
    • pp.416-417
    • /
    • 2006
  • The recent movement to deregulated and competitive electricity market requires new concepts against existing central dispatch in the system operation and planning. As power systems tend to be operated more closely to their ultimate ratings, the role of SCOPF(Security Constrained Optimal Power Flow) is changed. This paper deals with the proper Unit Commitment condition changed according to the conditions or configuration of power system. This goal of is paper is to obtain proper security and Optimal UC condition through the efficient usage of the sensitivity Factor against critical contingencies. The proposed mechanism has been tested on a sample system and results show more secure conditions against critical contingencies.

  • PDF

CSFs Extraction and AHP Importance Analysis for Construction Technology Services Evaluation in terms of Construction Manager (건설사업관리자(CMr) 측면에서 건설기술용역 평가의 CSFs 추출 및 AHP 중요도 분석)

  • Yang, Jin-Kook;Hong, Seong-Wook
    • Journal of the Architectural Institute of Korea Structure & Construction
    • /
    • v.36 no.3
    • /
    • pp.129-134
    • /
    • 2020
  • The current evaluation time period for the construction management service is the project completion or after project completion. Therefore, the construction manager has the following problems. First, it is difficult to prepare the evaluation due to the new field movement of the existing participating engineer. Next, the CM work is complex as well as extensive. Therefore, the critical success factors of the construction technology services evaluation are required as a systematic performance standard of CM work. In this study, we extracted the critical success factors that can systematically prepare the evaluation from the early stage of the project through in - depth interviews with experts. And, this study was analyze the priority of each factor by using AHP technique. As a result, the most important factors were related to the systemization of the preparation process, the construction manager work capabilities and practical construction management. And the priorities of all factors were analyzed high in the factors suggested by the owner groups. The results of this analysis are expected to provide the standards that construction management service performer carry out structured management of construction management throughout the project.

A Study on the Determination of Fracture Parameters for Rubber Toughened Polymeric Materials Using on Instrumented Charpy Impact Test (계장화 샤르피충격시험기를 이용한 고무보강 폴리머재료의 파괴인자 결정에 관한연구)

  • Park, Myeong-Gyun;Choe, Yeong-Sik;Park, Se-Man;Yang, Jin-Seung
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.26 no.8
    • /
    • pp.1520-1526
    • /
    • 2002
  • The Charpy and Izod impact tests are the most prevalent techniques used to characterize the effects of high impulse loads on ploymeric materials. An analysis method for rubber toughened PVC is suggested to evaluate critical dynamic strain energy release rates(G$\_$c/) from the Charpy impact energy measurements. An instrumented Charpy impact tester was used to extract ancillary information concerning fracture parameters in addition to total fracture energies and maximum critical loads. The dynamic stress intensity factor Kid was computed for varying amounts of rubber contents from the obtained maximum critical loads and also toughening effects were investigated as well.

Critical Success Factors for Project Management Information System in Construction

  • Lee, Seul-Ki;Yu, Jung-Ho
    • Journal of Construction Engineering and Project Management
    • /
    • v.1 no.1
    • /
    • pp.25-30
    • /
    • 2011
  • With a focus on different aspects of PMIS in construction projects, various sets of critical success factors (CSFs) have been suggested in the literature such as IS Success Model by various researchers. It is crucial to explore the relative importance and groupings of these factors. This paper aims to identify CSFs associated with Project Management Information System (PMIS) in construction projects, and explore their ranking and underlying relationship. CSFs for PMIS identified through a literature review, and consolidated by interviews and pilot studies with professionals in construction industry. A questionnaire instrument was sent out to experienced users (Construction Manager and Constructor) in Korea, and 253 completed questionnaires were retrieved. To increase the generalizability of the results, the respondents were spread across construction site. Using factor analysis and considering the high importance of the factor, CSFs were grouped into three dimensions. All these three groupings and their relationship were included in a framework for successful PMIS in construction projects. These findings help to clarify what the high prioritized factors are, and could also be used as an assessment tool to evaluate the performance of PMIS and thus help to identify areas for improvement.

An Analysis of Critical Management Factors for Construction Failure on the Apartment Structural Framework using FMEA (FMEA 기법을 활용한 공동주택 골조공사의 건설실패 핵심관리요인 분석)

  • Oh, Chi-Don;Park, Chan-Sik
    • Korean Journal of Construction Engineering and Management
    • /
    • v.13 no.3
    • /
    • pp.78-88
    • /
    • 2012
  • Previous construction failure researches were focused on the utilization plan based on failure information and development of failure classification. However, it has limitation to set up the plan for prevention of construction failure due to the lack of the number of on-site staffs. In order to prevent effectively construction failure, a prevention plan should be established through quantitative evaluation of failure causes. The purpose of this study is to suggest the assessment method for selection Critical Management Factor(CMF) and to analyze the CMF on the apartment structural framework using FMEA(Failure Mode and Effective Analysis) which is one of the methods of quantitative evaluation. The element of risk evaluation separated degree of failure risk and prevention respectively. The assessment method for selection of CMF can be utilized for planning proactive solutions on the failure, and it can be also selected critical factors about each project phases, type of facility and construction work.

Estimation of fracture toughness of cast steel container from Charpy impact test data

  • Bellahcenea, Tassadit;Aberkane, Meziane
    • Steel and Composite Structures
    • /
    • v.25 no.6
    • /
    • pp.639-648
    • /
    • 2017
  • Fracture energy values KV have been measured on cast steel, used in the container manufacture, by instrumented Charpy impact testing. This material has a large ductility on the upper transition region at $+20^{\circ}C$ and a ductile tearing with an expended plasticity before a brittle fracture on the lower transition region at $-20^{\circ}C$. To assess the fracture toughness of this material we use, the $K_{IC}$-KV correlations to measure the critical stress intensity factor $K_{IC}$ on the lower transition region and the dynamic force - displacement curves to measure the critical fracture toughness $J{\rho}_C$, the essential work of fracture ${\Gamma}_e$ on the upper transition region. It is found, using the $K_{IC}$-KV correlations, that the critical stress intensity factor $K_{IC}$ remains significant, on the lower transition region, which indicating that our testing material preserves his ductility at low temperature and it is apt to be used as a container's material. It is, also, found that the $J_{\rho}-{\rho}$ energetic criterion, used on the upper transition region, gives a good evaluation of the fracture toughness closest to those found in the literature. Finally, we show, by using the ${\Gamma}_e-K_{IC}$ relation, on the lower transition region, that the essential work of fracture is not suitable for the toughness measurement because the strong scatter of the experimental data. To complete this study by a numerical approach we used the ANSYS code to determine the critical fracture toughness $J_{ANSYS}$ on the upper transition region.