• IMMUNE NETWORK
• /
• 제5권2호
• /
• pp.105-109
• /
• 2005

Background: Dendritic cells (DCs) are the most potent APCs (antigen-presenting cells) and playa critical role in immune responses. Galectin-3 is a biological lectin with a beta-galactoside binding affinity. Recently, proteomic analysis revealed the presence of galectin-3 in the exosome of mature DCs. However, the expression and function of galectin-3 in DCs remains unclear yet. Methods: We used bone marrow-derived DCs of mouse and showed the expression of galectin-3 in DCs by using flow cytometry analysis and Western blot analysis. Results: Galectin-3 was determined as single band of 35 kDa in Western blot analysis. Flow cytometry analysis showed the major growth factor for DCs, granulocyte-macrophage colony stimulating factor (GM-CSF) and maturing agents, anti-CD40 monoclonal antibody (mAb) and lipopolysaccharide (LPS) consistently increased the intracellular expression of galectin-3 in DCs compared to medium alone. In addition, DCs treated with maturing agents did marginally express galectin-3 on their surface. Conclusion: This study suggests that galectin-3 in DCs may be regulated by critical factors for DC function.

• 한국복합재료학회:학술대회논문집
• /
• 한국복합재료학회 2003년도 춘계학술발표대회 논문집
• /
• pp.180-183
• /
• 2003

In this work. a potential inexpensive epoxy resin. epoxidized soybean oil (ESO) was synthesized and applied as a toughening agent for 4.4'-tetradiglycidyl diaminodiphenyl methane (TGDDM). The chemical structure of ESO was characterized by FT-IR, $^1H NMR, and ^{13}C NMR$ spectroscopy. The curing behaviors. thermal stabilities. fracture toughness. and flexural strength of TGDDM/ESO blend systems were investigated by using the dynamic DSC. thermogravimetric analysis (TGA). and flexural tests. The thermal stabilities of TGDDM/ESO blend systems were decreased with increasing ESO contents. whereas the critical stress intensity factor ($K_{IC}$) and flexural strength ($\sigma_f$) were increased with ESO contents up to 10 wt% ESO.

• 한국건축시공학회:학술대회논문집
• /
• 한국건축시공학회 2011년도 춘계 학술논문 발표대회 1부
• /
• pp.181-184
• /
• 2011

The earlier studies which are related to conflict management for urban regeneration project were based on limited case-studies on a specific phase. In addition, those studies did not considered a multidisciplinary approach for critical factor of conflict occurrence. In this reason, to establish a practical management or a policy is limited. In this paper, 'Good communication and information sharing' and 'Cooperativeness of stakeholders on project' are defined by critical factors for minimization of conflict between stakeholders. Furthermore we analysis the influence of those factors to minimization of conflict using path-analysis. This paper contributes to increase the efficiency of conflict management through understanding influence of each factors.

• 한국수자원학회논문집
• /
• 제32권4호
• /
• pp.469-478
• /
• 1999

한수관내 침전물의 퇴적을 방지하기 위하여는 최저유속과 에너지경사, 관경을 산정하여 제시하여야 되는데 이들 수치를 바로 결정하는 양해법 산정식들을 개발하였다. 이를 위하여 토사의 임계전단력과 상용관 마찰계수 산정을 위하여 지수형 산정식들을 도입하였으며, 이들 지수형 산정식들은 기존 실험관측자료를 이용하여 개발되었다. 제시된 수치들의 적합성을 판별하기 위하여 여러 예들을 본 연구에서 개발된 산정식들을 적용하여 검토하였다.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2006년도 제37회 하계학술대회 논문집 A
• /
• pp.416-417
• /
• 2006

The recent movement to deregulated and competitive electricity market requires new concepts against existing central dispatch in the system operation and planning. As power systems tend to be operated more closely to their ultimate ratings, the role of SCOPF(Security Constrained Optimal Power Flow) is changed. This paper deals with the proper Unit Commitment condition changed according to the conditions or configuration of power system. This goal of is paper is to obtain proper security and Optimal UC condition through the efficient usage of the sensitivity Factor against critical contingencies. The proposed mechanism has been tested on a sample system and results show more secure conditions against critical contingencies.

• 대한건축학회논문집:구조계
• /
• 제36권3호
• /
• pp.129-134
• /
• 2020

The current evaluation time period for the construction management service is the project completion or after project completion. Therefore, the construction manager has the following problems. First, it is difficult to prepare the evaluation due to the new field movement of the existing participating engineer. Next, the CM work is complex as well as extensive. Therefore, the critical success factors of the construction technology services evaluation are required as a systematic performance standard of CM work. In this study, we extracted the critical success factors that can systematically prepare the evaluation from the early stage of the project through in - depth interviews with experts. And, this study was analyze the priority of each factor by using AHP technique. As a result, the most important factors were related to the systemization of the preparation process, the construction manager work capabilities and practical construction management. And the priorities of all factors were analyzed high in the factors suggested by the owner groups. The results of this analysis are expected to provide the standards that construction management service performer carry out structured management of construction management throughout the project.

• 대한기계학회논문집A
• /
• 제26권8호
• /
• pp.1520-1526
• /
• 2002

The Charpy and Izod impact tests are the most prevalent techniques used to characterize the effects of high impulse loads on ploymeric materials. An analysis method for rubber toughened PVC is suggested to evaluate critical dynamic strain energy release rates(G$\_$c/) from the Charpy impact energy measurements. An instrumented Charpy impact tester was used to extract ancillary information concerning fracture parameters in addition to total fracture energies and maximum critical loads. The dynamic stress intensity factor Kid was computed for varying amounts of rubber contents from the obtained maximum critical loads and also toughening effects were investigated as well.

• Journal of Construction Engineering and Project Management
• /
• 제1권1호
• /
• pp.25-30
• /
• 2011

With a focus on different aspects of PMIS in construction projects, various sets of critical success factors (CSFs) have been suggested in the literature such as IS Success Model by various researchers. It is crucial to explore the relative importance and groupings of these factors. This paper aims to identify CSFs associated with Project Management Information System (PMIS) in construction projects, and explore their ranking and underlying relationship. CSFs for PMIS identified through a literature review, and consolidated by interviews and pilot studies with professionals in construction industry. A questionnaire instrument was sent out to experienced users (Construction Manager and Constructor) in Korea, and 253 completed questionnaires were retrieved. To increase the generalizability of the results, the respondents were spread across construction site. Using factor analysis and considering the high importance of the factor, CSFs were grouped into three dimensions. All these three groupings and their relationship were included in a framework for successful PMIS in construction projects. These findings help to clarify what the high prioritized factors are, and could also be used as an assessment tool to evaluate the performance of PMIS and thus help to identify areas for improvement.

• 한국건설관리학회논문집
• /
• 제13권3호
• /
• pp.78-88
• /
• 2012

국내의 건설실패 관련 연구는 체계화된 실패정보 분류체계 및 실패정보의 활용을 위한 방안을 제시하는 것에 초점을 맞추고 있다. 그러나, 건설현장의 한정된 관리자가 건설실패를 유발하는 다양한 원인에 대한 예방대책을 수립하는 것은 한계가 있다. 따라서, 효율적인 건설실패 예방활동이 이루지기 위해서는 많은 실패원인에 대한 정량적 평가를 통해 우선순위를 정하여 효율적인 예방대책이 수립되어야 한다. 이에 본 연구는 정량적인 평가를 통해 실패를 유발하는 핵심관리요인을 도출 할 수 있도록 FMEA(Failure Mode and Effect Analysis) 기법을 활용한 건설실패 핵심관리요인 선정방법을 제시하고, 공동주택 골조공사를 대상으로 핵심관리요인을 분석하는 것을 목적으로 하였다. 이를 위해 FMEA 기법의 위험도를 실패 위험성과 예방성으로 구분하여 평가할 수 있도록 하였다. 본 연구에서 제시한 핵심관리요인 평가방법은 건설실패의 사전예방대책을 효율적으로 수립하는데 활용될 수 있으며, 향후 유사한 연구를 통해 프로젝트 수행 단계별 혹은 다양한 시설 및 공종에 대한 핵심관리요인을 도출하는데 활용될 수 있을 것으로 기대된다.

• Steel and Composite Structures
• /
• 제25권6호
• /
• pp.639-648
• /
• 2017

Fracture energy values KV have been measured on cast steel, used in the container manufacture, by instrumented Charpy impact testing. This material has a large ductility on the upper transition region at $+20^{\circ}C$ and a ductile tearing with an expended plasticity before a brittle fracture on the lower transition region at $-20^{\circ}C$. To assess the fracture toughness of this material we use, the $K_{IC}$-KV correlations to measure the critical stress intensity factor $K_{IC}$ on the lower transition region and the dynamic force - displacement curves to measure the critical fracture toughness $J{\rho}_C$, the essential work of fracture ${\Gamma}_e$ on the upper transition region. It is found, using the $K_{IC}$-KV correlations, that the critical stress intensity factor $K_{IC}$ remains significant, on the lower transition region, which indicating that our testing material preserves his ductility at low temperature and it is apt to be used as a container's material. It is, also, found that the $J_{\rho}-{\rho}$ energetic criterion, used on the upper transition region, gives a good evaluation of the fracture toughness closest to those found in the literature. Finally, we show, by using the ${\Gamma}_e-K_{IC}$ relation, on the lower transition region, that the essential work of fracture is not suitable for the toughness measurement because the strong scatter of the experimental data. To complete this study by a numerical approach we used the ANSYS code to determine the critical fracture toughness $J_{ANSYS}$ on the upper transition region.