• The Journal of Asian Finance, Economics and Business
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• 제9권7호
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• pp.205-217
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• 2022

The purpose of this study was to explore the relationship between agricultural insurance, agricultural loans, and the agricultural industry and find ways to consolidate and improve the interactive development between these three systems. We collected relevant data from 2009 to 2019 in 15 provinces of China and constructed a coupled coordination model to analyze the data. The results are as follows: First, the eastern part of China was ahead of the central and western parts in terms of agricultural loans and the agricultural industry, while the western part was ahead of the central and eastern parts in terms of agricultural insurance. Second, the coupling degree of the three systems in all 15 provinces reached an extremely high level. Third, all 15 provinces showed an overall continuous rise in coupling coordination degree. In 2019, eight provinces reached the medium-level coupling coordination development, and seven provinces were in a state of barely coupling coordination development. The three systems formed a mutually reinforcing relationship and basically entered a state of coordinated development. Finally, there was a great development gap between different regions of China concerning the coordinated development of the three systems, therefore, innovative development is urgently needed to further promote the coordinated development level.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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• pp.251-256
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• 1994

Integration of intelligent robot workcell is now a hot issue in CIM and robotics area. This piper dealt with relatively low-level essential topics, i.e., multi-robot coordination and real-time communication for the integration of intelligent robot workcell. For the coordination of multi-robot system, the tightly-coupled coordination is proposed using the various sensors. In order to handle the numerous communication data, time-critical communication network (Field-bus) is introduced and investigated. Finally, intelligent robot workcell is suggested using the Mini-MAP and Field-bus.

• 대한기계학회논문집A
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• 제26권9호
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• pp.1822-1830
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• 2002

The paper describes the development of a decomposition based multidisciplinary design optimization (MDO) method that coordinates each of disciplinary subspace optimization (DSO). A multidisciplinary design system considered in the present study is decomposed into a number of subspaces based on their own design objective and constraints associated with engineering discipline. The coupled relations among subspaces are identified by interdisciplinary design variables. Each of subsystem level optimization, that is DSO would be performed in parallel, and the system level coordination is determined by the first order optimal sensitivities of subspace objective functions with respect to interdisciplinary design variables. The central of the present work resides on the formulation of system level coordination strategy and its capability in decomposition based MDO. A fluid-structure coupled design problem is explored as a test-bed to support the proposed MDO method.

• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2010년도 춘계학술발표대회 초록집
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• pp.50-50
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• 2010

최근 토요타 자동차의 대량 리콜 사태로 안전과 관련된 자동차 품질에 대한 관심과 중요성이 크게 부각되었다. 본 연구에서는 나날이 높아지고 있는 자동차 품질 기준과 생산 비용 절감, 공정 자동화 요구에 부응하기 위한 차체 저항 점 용접부 품질 검사 자동화 기술 개발을 위해 적용 가능한 센서들을 비교, 검토하였다. 알려진 비파괴 검사 방법은 초음파, 와전류, 방사선 검사법 등 다양한 방법들이 존재하지만, 이 연구에서는 생산 라인 현장 적용이 가능한 소형 센서들을 중심으로 검토 영역을 제한하였다. 검토된 비파괴 검사 방법은 총 5가지 종류로 종래의 수동 초음파 검사법, 집적된 탐촉자를 이용한 3차원 초음파 검사법, NAUT(Non-contact Air-coupled Ultrasonic Test), EMAT(EletroMagnetic Acoustic Test), 그리고 너겟 프로파일러$^{TM}$이다. 이 연구에서는 각 검사법의 원리와 장단점을 설명하고 생산 라인 적용에 필요한 필수 항목들에 대해 고찰하였다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집C
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• pp.380-385
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• 2001

The paper presents a new multidisciplinary design optimization architecture using optimal sensitivity and coordination of interdisciplinary design variables. Original design problem is decomposed into a number of sub-problems that represent individual engineering analysis. The coupled effects between sub-problems are computed by interdisciplinary design variables. System level coordination is determined by optimal parameter sensitivity calculated by finite difference method. The proposed. MDO strategy is applied to a simplified model of rotorcraft blade design associated with structures and aerodynamic disciplines.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 A
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• pp.406-409
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• 1993

Integration of intelligent robot workcell is now a hot issue in CIM and robotics area. This paper dealt with relatively low level essential topics. i. e., multi-robot coordination and real-time communication for the integration of intelligent robot workcell. For the coordination of multi-robot system, the tightly-coupled coordination is proposed using the various sensors. In order to handle the numerous communication data, time-critical communication network (field-bus) is introduced and investigated. Finally, intelligent robot workcell is suggested using the mini-MAP and field-bus.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 가을 학술발표회 논문집
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• pp.359-369
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• 1999

The paper describes the study of concurrent subspace optimization(CSSO) for coupled multidisciplinary design optimization (MDO) techniques in mechanical systems. This method is a solution to large scale coupled multidisciplinary system, wherein the original problem is decomposed into a set of smaller, more tractable subproblems. Key elements in CSSO are consisted of global sensitivity equation(GSE), subspace optimization (SSO), optimum sensitivity analysis(OSA), and coordination optimization problem(COP) so as to inquiry valanced design solutions finally, Automatic differentiation has an ability to provide a robust sensitivity solution, and have shown the numerical numerical effectiveness over finite difference schemes wherein the perturbed step size in design variable is required. The present paper will develop the automatic differentiation based concurrent subspace optimization(AD-CSSO) in MDO. An automatic differentiation tool in FORTRAN(ADIFOR) will be employed to evaluate sensitivities. The use of exact function derivatives in GSE, OSA and COP makes Possible to enhance the numerical accuracy during the iterative design process. The paper discusses how much influence on final optimal design compared with traditional all-in-one approach, finite difference based CSSO and AD-CSSO applying coupled design variables.

• BMB Reports
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• 제56권11호
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• pp.575-583
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• 2023

Mitochondria, fundamental cellular organelles that govern energy metabolism, hold a pivotal role in cellular vitality. While consuming dioxygen to produce adenosine triphosphate (ATP), the electron transfer process within mitochondria can engender the formation of reactive oxygen species that exert dual roles in endothelial homeostatic signaling and oxidative stress. In the context of the intricate electron transfer process, several metal ions that include copper, iron, zinc, and manganese serve as crucial cofactors in mitochondrial metalloenzymes to mediate the synthesis of ATP and antioxidant defense. In this mini review, we provide a comprehensive understanding of the coordination chemistry of mitochondrial cuproenzymes. In detail, cytochrome c oxidase (CcO) reduces dioxygen to water coupled with proton pumping to generate an electrochemical gradient, while superoxide dismutase 1 (SOD1) functions in detoxifying superoxide into hydrogen peroxide. With an emphasis on the catalytic reactions of the copper metalloenzymes and insights into their ligand environment, we also outline the metalation process of these enzymes throughout the copper trafficking system. The impairment of copper homeostasis can trigger mitochondrial dysfunction, and potentially lead to the development of copper-related disorders. We describe the current knowledge regarding copper-mediated toxicity mechanisms, thereby shedding light on prospective therapeutic strategies for pathologies intertwined with copper dyshomeostasis.

• 대한전기학회논문지:전력기술부문A
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• 제48권8호
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• pp.917-923
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• 1999

This paper proposes an efficient method of hydro-thermal scheduling in coordination with head variation and hydraulically coupled plants using Evolutionary Programing(EP). Based on the EP technique, the proposed algorithm is capable of determining the global optimal solutions. The constraints such a power balance condition, water available condition and transmission losses are embedded and satisfied throughout the proposed EP approach. The effectiveness of the proposed approach is demonstrated on the test systems and compared to those of other method. The results show that the new approach obtains a more highly optimal solutions than the conventional other methods such as newton-raphson method, Dynamic Programming(DP), LU factorization.

• Biomolecules & Therapeutics
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• 제4권4호
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• pp.349-353
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• 1996

The present study examined pharmacokinetic profiles of KBP31705-Cl27 and KBP30603-901, new platinum coordination complexes synthesized as anticancer candidates, in comparison with two well-known platinum-containing anticancer agents, cisplatin and carboplatin in rats. Under sodium pentobarbital anesthesia of male Sprague-Dawley rats, urinary bladder, and femoral artery and vein were catheterized for urine collection, blood sampling and drug injection, respectively Following i.v. administration of cisplatin (2 mg/kg), KBP31705-C127 (2 mg/kg), carboplatin (20 mg/kg) or KBP30603-901 (20 mg/kg), blood samples were collected at 2, 4, 6, 8, 10, 15, 20, 30, 45, 60 and 120 minutes. Urine samples were collected at 1-hr interval for 4 hr. Platinum concentrations in plasma and urine were measured using an inductively coupled plasmamass spectrometer. The plasma concentration-time curves were biphasic for all drugs during the time period studied. Compared with cisplatin, KBP31705-C127 showed similar decay patters in the alpha- and betaphases with slightly lower plasma concentrations. Urinary platinum excretion for cisplatin and KBP31705-C 127 was 56 and 52% of the administered dose in 4 hr, respectively. With regard to carboplatin and KBP 30603-901, a similar decay pattern was also observed in the alpha-phase. The half life of KBP30603-901 in the beta-phase, however, was much longer than that of carboplatin, which was consistent with the urinary excretion results that 46 and 59% of the administered dose were excreted in the urine in 4hr, respectively. The results suggest that platinum coordination complexes are primarily excreted via the renal route and KBP30603-901 can elicit longer duration of action due to slower renal excretion compared to carboplatin.