• KSBB Journal
• /
• 제25권3호
• /
• pp.205-214
• /
• 2010

역류크로마토그래피 (counter-current chromatography, CCC)는 일련의 분배과정을 한 개의 튜브 내에서 연속적으로 일어나도록 고안된 시스템으로서 컬럼으로는 polytetrafluoroethylene(PTFE) 튜브가 다층으로 감겨있는 원통형의 홀더 3개가 서로 기어를 통해 물려있으며, 홀더가 회전과 공전을 통해 튜브의 꼬임을 방지하는 rotary seal-free flow centrifuge 시스템으로 되어있다. 역상 HPLC (reverse phase HPLC)에서는 고정상이 실리카에 결합된 유기물단 (organic moiety)이 수용성 이동상 물질에 의해서 용매화 (solvated)되는 반면 CCC는 실리카 대신에 강한 중력장에 의해 분리되는 자유로운 용매가 고정상이 되며 이 고정상의 부피비율은 20-30%에 이른다. 즉 고체담체에 결합된 유기관능기 대신에 물과 섞이지 않는 hexane 같은 유기용제가 고정상으로 사용되는 것이다. 고속역류크로마토그래피 (high-performance countercurrent chromatography, HPCCC)는 CCC의 기능을 향상시킨 분리시스템으로서 높은 중력장하에서 높은 이동상 속도와 높은 분리효율과 짧은 분리시간을 특징으로 하고 있다. 특히 mg 단위에서 kg 단위로의 스케일업이 선형적으로 가능하다는 큰 장점을 지니고 있다. 이 총설에서는 현재까지 개발된 CCC의 일반적인 이론을 간략히 정리하고 최신 HPCCC 장비의 적용 예를 살펴보고 그 응용분야로서 생리활성물질의 분리 및 정제와 관련된 연구동향을 정리하였다.

• 한국원자력학회:학술대회논문집
• /
• 한국원자력학회 1999년도 춘계학술발표회요약집
• /
• pp.108-108
• /
• 1999

• 설비공학논문집
• /
• 제12권1호
• /
• pp.102-111
• /
• 2000

A numerical model which simulates the simultaneous heat and mass transfer within a vertical tube GAX absorber was developed. The ammonia vapor and the solution liquid are in counter-current flow, and the hydronic fluid flows counter to the solution liquid. The film thickness and the velocity distribution of the liquid film were obtained by matching the shear stress at the liquid-vapor interface. Two-dimensional diffusion and energy equations were solved in the liquid film to give the temperature and concentration, and a modified Colburn-Drew analysis was used for the vapor phase to determine the heat and mass fluxes at the liquid-vapor interface. The model was applied to a GAX absorber to investigate the absorption rates, temperature and concentration profiles, and mass flow rates of liquid and vapor phases. It was shown that the mass flux of water was negligible compared with that of ammonia except the region near the liquid inlet. Ammonia absorption rate increases rapidly near the liquid inlet and decrease slowly. Both the absorption rate of ammonia vapor and the desorption rate of water near the liquid inlet increase as the vapor mass flow rate increases, but the mass fluxes of the ammonia and the water near the liquid outlet decrease as the mass flow rate of the vapor increases.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2007년도 춘계학술대회B
• /
• pp.3440-3445
• /
• 2007

For proton exchange membrane fuel cell, it is very important to design the flow channel on separation plate optimally to maximize the current density at same electrochemical reaction surface and reduce the concentration polarization occurred at high current density. In this paper, three dimensional computation model including anode and cathode domain together was developed to examine effects of flow patterns and operation conditions such as humidity and operating temperature on performance of fuel cell. Results show that voltage at counter flow condition is higher than that at coflow condition in parallel and interdigitated flow pattern. And fuel cell with interdigitated flow pattern which has better mass transport by convection flow through gas diffusion layer has higher performance than with parallel flow pattern but its pressure drop is increased such that the trade off between performance and pressure drop should be considered for selection of flow pattern of fuel cell.

• 한국수소및신에너지학회논문집
• /
• 제30권2호
• /
• pp.147-154
• /
• 2019

In this study, effects of flow types and size of molten carbonate fuel cells (MCFCs) were investigated using CFD simulation. In the simulation, the current collector of MCFCs were assumed to be an porous media. With the area of $0.09m^2$, the effect of flow types such as Co-flow, Counter-flow, Cross-flow were studied. After that the effect of the size and flow direction was studied. Among three-flow types, MCFCs with co-flow type shows more uniform distribution and current density distribution.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2000년도 추계학술대회논문집B
• /
• pp.124-129
• /
• 2000

The flow of liquid and vapor is investigated in trapezoidal grooves. The effect of variable shear stress along the interface of the liquid and vapor is studied for both co-current and counter-current flows. Velocity contours and results fur the friction are obtained for both trapezoidal grooves. An approximate relation that was previously utilized for the friction for the liquid was modified to obtain accurate agreement with the results for trapezoidal grooves.

• 대한기계학회논문집
• /
• 제18권5호
• /
• pp.1338-1346
• /
• 1994

The objective of this study is to investigate the effect of various parameters, such as temperature, mean current density and voltage on the performance of phosphoric acid fuel cell (PAFC) by numerical analysis. Two types of flow passages, which are Z-parallel type and Z-counter type, are evaluated to obtain the best current density and temperature distribution. Parametric studies and sensitivity analysis of the PAFC system's operation in single cell are accomplished. A steady state simulation of the entire system is developed using nonlinear ordinary differential equations. The finite difference method and trial and error procedures are used to obtain a solution.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2006년도 추계 학술대회논문집
• /
• pp.93-96
• /
• 2006

The heat transfer enhancement by pulsatile flow in the plate heat exchanger has been investigated numerically in the present study. The numerical study was performed in the range of the mass flux from 0.04 to 0.12 kg/s. The results showed that the pulsatile flow produces resonating vortex shedding at the groove sharp edges and a strong transient vortex rotation within the grooved channels. As a result, the mixing between the trapped volume in the grooved cavity and the main stream was enhanced. Good agreements between the predictions and measured data are obtained in steady flow. And the heat transfer of pulsatile flow is about 2.4 times than steady flow when frequency is 10 Hz and the mass flux of cold side is 0.04 kg/s.

• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2004년도 추계 학술대회논문집
• /
• pp.127-130
• /
• 2004

In this study, three-dimensional numerical calculations are peformed to simulate the flow and heat transfer in helically coiled tube steam generator employing a commercial CFD (Computational Fluid Dynamics) code. The problem considered herein includes the boiling phase change flow of tube side fluid and the single-phase counter-current flow of shell side hot fluid transferring heat to the tube side flow thru the tube wall. Detailed investigations are performed for both shell-side and tube-side flow fields in terms of density and volume fractions of each phase of fluids as well as for the tube wall heat transfer field in terms of heat transfer coefficients.

• 디지털융복합연구
• /
• 제14권6호
• /
• pp.245-251
• /
• 2016

3차원 모델링을 이용하여 연료전지의 유로형상과 유체의 흐름 방향에 따른 연료전지의 성능에의 영향성을 분석을 수행하였다. 본 연구에서 연료전지 내부의 각 유로형상과 유동장의 변화에 전류밀도와 온도의 분포가 어떻게 이루어져 있는지를 분석하였고, 연료전지 단위셀의 전체적인 성능을 분석하였다. 3차원 모델링을 수행하기 위하여 Navier-Stokes 방정식을 전산유체역학을 이용하여 풀었다. 전산유체역학에 전기화학반응의 모델을 융합하여 계산을 수행하였다. 또한, 본 연구에서는 직선유로와 실제 사용되는 형태인 직사각형 모양의 유로형태를 모사하여 유로구조의 영향성을 분석하였다. 그리고 유체의 유동장을 변형시켜 그 영향성과 결과를 비교해 보았다. 본 전산모사 연구를 통하여 연료가 풍부한 부분보다는 산소가 풍부한 부분에서 전류밀도가 보다 높은 것을 확인할 수 있었다. 또한 전반적으로 전류밀도가 높은 곳에서 온도가 높은 것으로 확인할 수 있었다. 본 연구를 통하여 온도의 분포와 유로형상과 유동장 그리고 전류밀도의 연관성을 확인할 수 있었다.