• Journal of the Korean Society of Clothing and Textiles
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• v.13 no.1 s.29
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• pp.79-87
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• 1989

In the part 1 and 2, relations were found between fundmental mechanical properties and primary hand values, performance of Korean women's summer and fall & winter fabrics. In this paper, in order to investigate the hand values and mechanical properties such as tensile, shearing, bending, compression, surface and thickness & weight of the core-spun yarn woven fabrics for Korean folk clothes were measured by KES-F system. The experimental results are statistically analyzed in the aspects of the mechanical properties, their effects on the hand values, formation of weared clothes and transformation behavior. The correlation in the hand values are analyzed, too. Furthermore, there mechanical properties are discussed in comparison with those values for kimono fabrics. The main results are summarized as follows: 1. The core-spun yarn woven fabrics for Korean folk clothes have box-shaped silhouette based on higher bending rigidity and shear elasticity. 2. The core-spun yarn woven fabrics for Korean folk clothes are inferior to silk fabrics, superior to polyester fabrics in formation. 3. A drapability and wrinkle recovery of core-spun yarn woven fabrics for Korean folk clothes formation for weared clothes are inferior to polyester fabrics, superior to silk fabrics. 4. A primary factor of mechanical properties contribute to the hand values of core-spun yarn woven fabrics for Korean folk clothes are same as the Korean women's winter fabrics, except for flexibility with soft feeling. 5. As for the hand values of core-spun yarn woven fabrics for Korean folk clothes, stiffness, anti-drape stiffness are superior to those of polyester fabrics. And also, flexibility with soft feeling, scrooping feeling of core-spun yarn woven fabrics have greater values as compared with silk fabrics for Korean folk clothes.

• Journal of Applied Biological Chemistry
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• v.50 no.3
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• pp.109-114
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• 2007

Sar1p is a ras-related GTP-binding protein that functions in intracellular protein transport between the endoplasmic reticulum (ER) and the Golgi complex. The effector domain of Ras family proteins is highly conserved and this domain is functionally interchangeable in plant, yeast and mammalian Sar1. Using a recombinant Brassica sar1 protein (Bsar1p) harboring point mutations in its effector domain, we here investigated the ability of Sar1p to bind and hydrolyze GTP and to interact with the two sar1-specific regulators, GTPase activating protein (GAP) and guanine exchange factor (GEF). The T51A and T55A mutations impaired Bsar1p intrinsic GTP-binding and GDP-dissociation activity. In contrast, mutations in the switch domain of Bsar1 did not affect its intrinsic GTPase activity. Moreover, the P50A, P54A, and S56A mutations affected the interaction between Bsar1p and GAP. P54A mutant protein did not interact with two regulating proteins, GEF and GAP, even though the mutation didn't affect the intrinsic GTP-binding, nucleotide exchange or GTPase activity of Bsar1p.

• The Journal of the Convergence on Culture Technology
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• v.6 no.2
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• pp.199-205
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• 2020

The purpose of this study was to identify the factor Disaster Nursing Core Competencies in nursing college students. A descriptive correlation study design was used. The subjects were 144 university students of a university located in D and K city. The study used a Educational Needs on Disaster Nursing, Disaster Nursing Knowledge, Disaster Preparedness, Self-efficacy and Disaster Nursing Core Competencies. Data were collected from February 25 to March 15, 2019 and analyzed with t-test, pearson's correlation coefficient and multiple response analysis, stepwise multiple regression by using SPSS IBM 22.0 Program. The findings are follows: First, among the disaster nursing education methods, simulation based practice were the highest. Second, Disaster Nursing Core Competencies was positively correlated with Disaster Preparedness, self-efficacy and Disaster Knowledge. Third, the influencing factors in Disaster Nursing Core Competencies were Grade(β=0.343), Self-efficacy(β=0.329), Disaster Preparedness(β=0.282), Experience of practice in ER(β=0.159), adjusted R²=.532. Therefore, it is necessary to develop an Customized Disaster Program that can improve the Disaster Nursing Core Competencies of nursing college students based on the factors affecting the Disaster Nursing Core Competencies and Educational needs.

• Nuclear Engineering and Technology
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• v.37 no.1
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• pp.91-100
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• 2005

Kyung-hee Thorium Fuel (KTF), a heterogeneous thorium-based seed and blanket design concept for pressurized light water reactors, is being studied as an alternative to enhance proliferation resistance and fuel cycle economics of PWRs. The proliferation resistance characteristics of the KTF assembly design were evaluated through parametric studies using neutronic performance indices such as Bare Critical Mass (BCM), Spontaneous Neutron Source rate (SNS), Thermal Generation rate (TG), and Radio-Toxicity. Also, Fissile Economic Index (FEI), a new index for gauging fuel cycle economy, was suggested and applied to optimize the KTF design. A core loaded with optimized KTF assemblies with a seed-to-blanket ratio of 1: 1 was tested at the Korea Next Generation Reactor (KNGR), ARP-1400. Core design characteristics for cycle length, power distribution, and power peaking were evaluated by HELIOS and MASTER code systems for nine reload cycles. The core calculation results show that the KTF assembly design has nearly the same neutronic performance as those of a conventional $UO_2$ fuel assembly. However, the power peaking factor is relatively higher than that of conventional PWRs as the maximum Fq is 2.69 at the M$9^{th}$ equilibrium cycle while the design limit is 2.58. In order to assess the economic potential of a heterogeneous thorium fuel core, the front-end fuel cycle costs as well as the spent fuel disposal costs were compared with those of a reference PWR fueled with $UO_2$. In the case of comprising back-end fuel cycle cost, the fuel cycle cost of APR-1400 with a KTF assembly is 4.99 mills/KWe-yr, which is lower than that (5.23 mills/KWe-yr) of a conventional PWR. Proliferation resistance potential, BCM, SNS, and TG of a heterogeneous thorium-fueled core are much higher than those of the $UO_2$ core. The once-through fuel cycle application of heterogeneous thorium fuel assemblies demonstrated good competitiveness relative to $UO_2$ in terms of economics.

• Journal of vocational education research
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• v.37 no.2
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• pp.1-18
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• 2018

Recently human resources who have core competencies are regarded as an important factor in the labor market. However, there are few limitation about instruments to measure university students' core competencies. Recognizing this limitation, this study aimed to develop and validate the tests that could measure core competencies of students in universities. Among NCS core competencies, this study primarily focused on the self-development skill, organizational skill and resources management skill. This study concluded the proper definition of core competencies for university students, sub factors of 3 domains and questionnaire and validated its measurement. Implications of this study were discussed.

• Nuclear Engineering and Technology
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• v.21 no.4
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• pp.294-301
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• 1989

The Axial Power Distribution Monitoring System(APDMS) program was developed to calculate a detailed axial power distribution using two-level excore detector, cold leg temperature and control rod position signals. The unnormalized two-level excore detector signals were corrected for the rod shadowing factor determined by control rod position and for the temperature shadowing factor calculated based on cold leg temperature. A shape annealing matrix was then applied to the corrected excore detector response to yield peripheral power. After the core average power was obtained using linear relationship bet-ween core average and peripheral power, the boundary point power correction coefficient was applied to core average power in order to obtain boundary power for both upper and lower core axial boundaries. Then, the axial power distribution was synthesized by spline approximation. In spite of burnup, power level, control rod postion and axial offset changes, the comparisons of axial power distributions between BOXER simulation program and APDMS results showed good agreements within 5% root mean square error for Kori Unit 3 Cycle 4.

• Culinary science and hospitality research
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• v.17 no.4
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• pp.219-237
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• 2011

This study aims to investigate the effect of core-self evaluation on work-family facilitation(work to family facilitation, family to work facilitation), job satisfaction and turnover intention among non-regular workers in Korean food service industry. In order to examine the hypothesized relationships, frequency analysis, confirmatory factor analysis, reliability analysis, correlation analysis and covariance structure analysis were performed using SPSS(10.0) and AMOS(4.0). The results showed that core-self evaluation had a significantly positive effect on both of work to family facilitation and family to work facilitation. In the case of relationship between work-family facilitation and job satisfaction, only family to work facilitation had a positive effect on job satisfaction while there was no evidence of a significant relationship from work to family facilitation to job satisfaction. Additionally, job satisfaction had a significantly negative effect on turnover intention. The article concluded with managerial implications for managerial and future research directions.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.421-430
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• 2019

Background: The ginsenoside Rg3, one of active components of red ginseng, has chemopreventive and anticancer potential. Cancer stem cells retain self-renewal properties which account for cancer recurrence and resistance to anticancer therapy. In our present study, we investigated whether the standardized Korean Red Ginseng extract (RGE) and Rg3 could modulate the manifestation of breast cancer stem cell-like features through regulation of self-renewal activity. Methods: The effects of RGE and Rg3 on the proportion of $CD44^{high}/CD24^{low}$ cells, as representative characteristics of stem-like breast cancer cells, were determined by flow cytometry. The mammosphere formation assay was performed to assess self-renewal capacities of breast cancer cells. Aldehyde dehydrogenase activity of MCF-7 mammospheres was measured by the ALDEFLUOR assay. The expression levels of Sox-2, Bmi-1, and P-Akt and the nuclear localization of hypoxia inducible $factor-1{\alpha}$ in MCF-7 mammospheres were verified by immunoblot analysis. Results: Both RGE and Rg3 decreased the viability of breast cancer cells and significantly reduced the populations of $CD44^{high}/CD24^{low}$ in MDA-MB-231 cells. RGE and Rg3 treatment attenuated the expression of Sox-2 and Bmi-1 by inhibiting the nuclear localization of hypoxia inducible $factor-1{\alpha}$ in MCF-7 mammospheres. Suppression of the manifestation of breast cancer stem cell-like properties by Rg3 was mediated through the blockade of Akt-mediated self-renewal signaling. Conclusion: This study suggests that Rg3 has a therapeutic potential targeting breast cancer stem cells.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1519-1526
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• 2010

The behavior of peptide or protein solutes in saline aqueous solution is a fundamental topic in physical chemistry. Addition of ions can strongly alter the thermodynamic and physical properties of peptide molecules in solution. In order to study the effects of added ionic salts on protein conformation and dynamics, we have used the molecular dynamics (MD) simulations to investigate the behavior of Staphylococcus aureus Hfq protein under two different ionic concentrations: 0.1 M NaCl and 1.0 M NaCl in presence and absence of RNA (a hepta-oligoribonucleotide AU5G). Hfq, a global regulator of gene expression is highly conserved and abundant RNA-binding protein. It is already reported that in vivo the increase of ionic strength results in a drastic reduction of Hfq affinity for $Q{\beta}$ RNA and reduces the tendency of aggregation of Escherichia coli host factor hexamers. Our results revealed the crucial role of 0.1 M NaCl Hfq system on the bases with strong hydrogen bonding interactions and by stabilizing the aromatic stacking of Tyr42 residue of the adjacent subunits/monomers with the adenine and uridine nucleobases. An increase in RNA pore diameter and weakened compactness of the Hfq-RNA complex was clearly observed in 1.0 M NaCl Hfq system with bound RNA. Aggregation of monomers in Hfq and the interaction of Hfq with RNA are greatly affected due to the presence of high ionic strength. Higher the ionic concentration, weaker is the aggregation and interaction. Our results were compatible with the experimental data and this is the first theoretical report for the experimental study done in 1980 by Uhlenbeck group for the present system.

• Molecules and Cells
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• v.27 no.5
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• pp.563-570
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• 2009

We previously isolated the OsCBT gene, which encodes a calmodulin (CaM)-binding protein, from a rice expression library constructed from fungal elicitor-treated rice suspension cells. In order to understand the function of OsCBT in rice, we isolated and characterized a T-DNA insertion mutant allele named oscbt-1. The oscbt-1 mutant exhibits reduced levels of OsCBT transcripts and no significant morphological changes compared to wild-type plant although the growth of the mutant is stunted. However, oscbt-1 mutants showed significant resistance to two major rice pathogens. The growth of the rice blast fungus Magnaporthe grisea, as well as the bacterial pathogen Xanthomonas oryzae pv. oryzae was significantly suppressed in oscbt-1 plants. Histochemical analysis indicated that the hypersensitive-response was induced in the oscbt-1 mutant in response to compatible strains of fungal pathogens. OsCBT expression was induced upon challenge with fungal elicitor. We also observed significant increase in the level of pathogenesis-related genes in the oscbt-1 mutant even under pathogen-free condition. Taken together, the results support an idea that OsCBT might act as a negative regulator on plant defense.