• 제목/요약/키워드: Copy

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지방간 및 대사 인자들과 말초혈액 백혈구의 사립체 DNA copy 수와의 연관성 (Relationship Between Mitochondrial DNA Copy Number, Metabolic Abnormalities and Hepatic Steatosis)

  • 권길영;전대원
    • 한국산학기술학회논문지
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    • 제11권6호
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    • pp.2093-2098
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    • 2010
  • 지방간은 대사증후군의 한 형태로 인슐린저항성이 중요한 역할을 한다. 본 연구는 당뇨 및 대사 인자들과 연관성이 있는 것으로 알려진 말초혈액의 사립체 DNA (mtDNA) copy 수와 지방간 및 인슐린저항성 관련 인자와의 연관성을 알아보고자 하였다. 지방간 진단을 위해 음주력 설문과 복부 초음파 검사를 시행하였으며 실시간 중합효소 연쇄반응을 이용하여 말초혈액의 백혈구에서 mtDNA copy 수를 측정하였다. 총 445 명의 대상자 중 지방간이 있는군(fatty liver group)은 148 명이고 정상군은 297 명이었다. 지방간이 있는 군에서 정상군에 비해 mtDNA copy수가 유의하게 낮았다. 비알콜성 지방간과 알코올성 지방간 모두 지방간이 있는 군에서 말초혈액 mtDNA copy 수가 낮았다. 말초혈액의 mtDNA copy 수는 ALT, AST, $\gamma$-GTP, 체질량지수, 허리둘레, 이완기혈압, 유리지방산 수치와 역의 상관관계를 보였다. 말초혈액에서의 mtDNA copy 수는 지방간 여부 및 인슐린저항성 관련 대사 인자들과 높은 연관성이 있었다.

공간 데이터베이스의 중복 제어를 위한 Floating Primary Copy 기법 (Floating Primary Copy Method for Replica Control of Spatial Data)

  • 최진오
    • 한국멀티미디어학회:학술대회논문집
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    • 한국멀티미디어학회 2002년도 춘계학술발표논문집(상)
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    • pp.68-72
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    • 2002
  • CIS 응용에서 공간 객체들이 여러 사이트에 걸쳐 중복 저장되어 있다면, 이 객체들의 수정 시 일관성 제어를 위한 중복 제어 기법이 필요하다. 그러나, 일반적인 비즈니스 데이터를 위한 정통적인 중복 제어기법은 공간 데이터에는 그대로 사용될 수 없다. 공간 데이터의 수정은 긴 트랜 션을 필요로 하며, 또한 일반 데이터와 달리 데이터간의 공간 종속성을 지니기 때문이다. 본 논문은 기존의 Primary Copy 중복 제어 기법을 확장하며, time-stamp에 기반하여 Primary Copy 사이트가 변경되는 Floating Primary Copy 기법을 제안한다. 본 논문에서 제안하는 중복 제어 기법은 Primary Copy 사이트를 동적으로 변경함으로써, 긴 트랜 션의 중복 일관성 제어를 지원할 수 있다.

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A Multiple Features Video Copy Detection Algorithm Based on a SURF Descriptor

  • Hou, Yanyan;Wang, Xiuzhen;Liu, Sanrong
    • Journal of Information Processing Systems
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    • 제12권3호
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    • pp.502-510
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    • 2016
  • Considering video copy transform diversity, a multi-feature video copy detection algorithm based on a Speeded-Up Robust Features (SURF) local descriptor is proposed in this paper. Video copy coarse detection is done by an ordinal measure (OM) algorithm after the video is preprocessed. If the matching result is greater than the specified threshold, the video copy fine detection is done based on a SURF descriptor and a box filter is used to extract integral video. In order to improve video copy detection speed, the Hessian matrix trace of the SURF descriptor is used to pre-match, and dimension reduction is done to the traditional SURF feature vector for video matching. Our experimental results indicate that video copy detection precision and recall are greatly improved compared with traditional algorithms, and that our proposed multiple features algorithm has good robustness and discrimination accuracy, as it demonstrated that video detection speed was also improved.

Role of GSTM1 Copy Number Variant in the Prognosis of Thai Colorectal Cancer Patients Treated with 5-FU-based Chemotherapy

  • Pongtheerat, Tanett;Saelee, Pensri
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권10호
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    • pp.4719-4722
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    • 2016
  • Background: Glutathione S-transferase M1 (GSTM1) is involved in the detoxification of carcinogenic agents. DNA copy number variants of GSTM1 may be associated with cancer progression and may result in reduced survival time of various cancers. Determination of DNA copy number variants was here used to assess the association between GSTM1 copy number variant and pathological status and survival time of colorectal-cancer patients treated with 5-fluorouracil-based chemotherapy. Methods: One hundred thirteen Thai colorectal-cancer patients were investigated for GSTM1 copy number variant by real-time PCR. Relationships between gene copy number variants and clinico-pathological parameters were determined. Result: Associations were evident between GSTM1 copy number and stage of tumor (P = 0.026) and metastasis at diagnosis (P = 0.049), with odds ratio values of 0.2 and 0.3 respectively. Conclusions: GSTM1 copy number variant was here not related with reduced overall survival for the colorectal-cancer patients receiving 5-FU-based chemotherapy.

Copy Raising Construction in English: A Usage-based Perspective

  • Kim, Jong-Bok
    • 한국언어정보학회지:언어와정보
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    • 제16권2호
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    • pp.1-15
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    • 2012
  • In accounting for the so-called copy raising (CR) in English, the movement perspective has assumed that the embedded subject of the CR verb's sentential complement is raised to the matrix subject, leaving behind its pronominal copy. This kind of movement-based analysis raises both empirical and analytical issues, when considering variations in the pronominal copy constraint. This paper investigates the actual uses of the construction, using online-available corpora. Based on this corpus search, we classify two different types of copy raising predicates (genuine and perception), and discuss their grammatical properties in detail. We suggest that the simple copying rule couched upon movement operations is not enough to capture great variations in the uses of the construction, and show that interpretive constraints, e.g., perceptual characterization condition, play an important role in licensing the construction.

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비디오 복사방지를 위한 새로운 특징들의 성능평가 (Performance Evaluation of New Signatures for Video Copy Detection)

  • 현기호
    • 대한전자공학회논문지SP
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    • 제40권1호
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    • pp.96-102
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    • 2003
  • 비디오 복사 방지(video copy detection)는 기존의 워터마킹 방법과 반대의 개념으로, 비디오 스트림에 독특한 패턴을 첨가하는 워터마킹에 비해, 비디오 복사 방지 기법은 비디오의 복사판을 검출하기 위해 패턴을 첨가하지 않고 비디오의 내용 기반 특징(content-based signature)을 비교한다. 기존의 일반적인 내용 기반 복사 방지방법은 이미지 정합을 사용하였으나, 본 논문은 비디오 복사방지를 위해 가능한 두 가지의 새로운 순서정합(sequence matching) 알고리즘을 제안하고, 기존의 방법 중 칼라 정합 방법과 성능을 비교 분석하였다. 모션, 명암도와 칼라 기반 특징을 복사 방지 관점에서 비교하고, 영화클립에 대해 실험한 결과를 제시한다.

대용량 데이터의 전송 효율 및 기록 성능 향상을 위한 Zero Copy 기술 적용에 관한 연구 (A Study on the Application of Zero Copy Technology to Improve the Transmission Efficiency and Recording Performance of Massive Data)

  • 송민규;김효령;강용우;제도흥;위석오;이성모;김승래
    • 한국전자통신학회논문지
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    • 제16권6호
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    • pp.1133-1144
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    • 2021
  • Zero-copy는 메모리 무복사로도 불리는 기술로서 이에 대한 사용을 통해 사용자 영역과 커널 영역 간 컨텍스트 스위칭을 줄여 CPU의 부하를 최소화할 수 있다. 하지만 이 기술은 소규모의 랜덤한 파일을 전송하는 용도에 그치고, 대용량 파일 전송에는 아직 널리 활용되지 못하고 있다. 본 논문은 네트워크를 경유한 대용량 파일 처리에 있어서 Zero-copy의 실질적인 적용 방안에 대해 논의하고자 한다. 이를 위해 먼저 Zero-copy 기반으로 데이터를 전송, 저장할 수 있는 소규모 테스트베드 구축 및 프로그램을 개발하였다. 이후 세부 성능 평가를 통해 적용된 기술의 유용성을 세부 검증하고자 한다.

인쇄 광고의 카피 특성 분석 - 유머 광고를 중심으로 (Copy Style in Print Advertising : Focused on Humor Advertising)

  • 이광숙;구자휘
    • 한국인쇄학회지
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    • 제27권1호
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    • pp.73-87
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    • 2009
  • The purpose of this study is to provide a executive guideline of humor in Print advertising by analyzing the copy style. For this aim, in-depth analysis about the copy style of humor in Print advertising collected by the web-site of TV cf from 2005 to 2008 was performed. In conclusion, findings showed that the copy style in the pattern of expression was focused on the psychological arousal and incongruity and the pattern of damaging and attacking someone's prestige was considered to be significant in some degree. It was also found that the copy style of humor in Print advertising in the method of expression was focused on the factor of pun, jokes, double-meaning but the factor of satire, irony and turns of phrase was a minority.

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복사기의 HCI관점에서의 개선과 복사자들의 자세 개선 (Improvement of Copy-Machine in terms of Human-Computer Interface and Posture Improvement of Copy-Workers)

  • Young-Guk Kwon;Sang-Kyu Park
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2001년도 추계학술대회
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    • pp.139-143
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    • 2001
  • Work-related injurieshave become the issue in the twentieth century. Musculoskeletal disorders are the most common work-related injuriesand the most frequent from of work-related i11-health (more than 50% of total work-related injuries (BLS 1990)). The workers at copy shops have complained of pain in their back, legs, and shoulders. Most of them work for more than 8 hours a day. They have claimed that their pains were associated with repetitive and continuous work over a long term. The purpose of this research is to suggest an ergonomically comfortable redesign of the copy machine. This study was performed by conducting a survey of copy shop workers who have complained of job-related physical pain, and analyzing their working postures. The copy machine was ergonomically modified to reduce the workers' pain. The VIS10N 3000 software was used to analyze the posture. The analysis showed significant difference in the ranges of back and neck motion (p<0.05).

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Mitochondrial Genome Microsatellite Instability and Copy Number Alteration in Lung Carcinomas

  • Dai, Ji-Gang;Zhang, Zai-Yong;Liu, Quan-Xing;Min, Jia-Xin
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권4호
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    • pp.2393-2399
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    • 2013
  • Objective: Mitochondrial DNA (mtDNA) is considered a hotspot of mutations in various tumors. However, the relationship between microsatellite instability (MSI) and mtDNA copy number alterations in lung cancer has yet to be fully clarifieds. In the current study, we investigated the copy number and MSI of mitochondrial genome in lung carcinomas, as well as their significance for cancer development. Methods: The copy number and MSI of mtDNA in 37 matched lung carcinoma/adjacent histological normal lung tissue samples were examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) assays for sequence variation, followed by sequence analysis and fluorogenic 5'-nuclease real-time PCR. Student's t test and linear regression analyses were employed to analyze the association between mtDNA copy number alterations and mitochondrial MSI (mtMSI). Results: The mean copy number of mtDNA in lung carcinoma tissue samples was significantly lower than that of the adjacent histologically normal lung tissue samples (p<0.001). mtMSI was detected in 32.4% (12/37) of lung carcinoma samples. The average copy number of mtDNA in lung carcinoma samples containing mtMSI was significantly lower than that in the other lung carcinoma samples (P<0.05). Conclusions: Results suggest that mtMSI may be an early and important event in the progression of lung carcinogenesis, particularly in association with variation in mtDNA copy number.