• Title/Summary/Keyword: Copy

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Relationship Between Mitochondrial DNA Copy Number, Metabolic Abnormalities and Hepatic Steatosis (지방간 및 대사 인자들과 말초혈액 백혈구의 사립체 DNA copy 수와의 연관성)

  • Kwon, Kil-Young;Jun, Dae-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.6
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    • pp.2093-2098
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    • 2010
  • Insulin resistance plays a central role in fatty liver, a part of the metabolic syndrome. This study examined the relationship between fatty liver, metabolic abnormalities and mitochondrial DNA [mtDNA] copy number in peripheral blood that is correlated with diabetes or metabolic markers. Fatty liver was assessed by questionnaire on alcohol consumption and abdominal ultrasonography. MtDNA copy number in peripheral leukocytes was measured by a real-time quantitative polymerase chain reaction [PCR]. Among 445 subjects, 148 subjects had hepatic steatosis and 297 were controls. mtDNA copy number was significantly lower in fatty liver group in comparison with that of normal finding group. This result is similar in both groups, alcoholic or non-alcoholic fatty liver group. MtDNA copy number was inversely correlated with alanine aminotransferase [ALT], aspartate aminotransferase [AST], gamma-glutamyltransferase [$\gamma$-GTP], body mass index [BMI], waist circumference, diastolic blood pressure, and free fatty acid. MtDNA copy number in peripheral leukocytes was associated with fatty liver and insulin resistance related factors.

Floating Primary Copy Method for Replica Control of Spatial Data (공간 데이터베이스의 중복 제어를 위한 Floating Primary Copy 기법)

  • 최진오
    • Proceedings of the Korea Multimedia Society Conference
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    • 2002.05c
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    • pp.68-72
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    • 2002
  • CIS 응용에서 공간 객체들이 여러 사이트에 걸쳐 중복 저장되어 있다면, 이 객체들의 수정 시 일관성 제어를 위한 중복 제어 기법이 필요하다. 그러나, 일반적인 비즈니스 데이터를 위한 정통적인 중복 제어기법은 공간 데이터에는 그대로 사용될 수 없다. 공간 데이터의 수정은 긴 트랜 션을 필요로 하며, 또한 일반 데이터와 달리 데이터간의 공간 종속성을 지니기 때문이다. 본 논문은 기존의 Primary Copy 중복 제어 기법을 확장하며, time-stamp에 기반하여 Primary Copy 사이트가 변경되는 Floating Primary Copy 기법을 제안한다. 본 논문에서 제안하는 중복 제어 기법은 Primary Copy 사이트를 동적으로 변경함으로써, 긴 트랜 션의 중복 일관성 제어를 지원할 수 있다.

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A Multiple Features Video Copy Detection Algorithm Based on a SURF Descriptor

  • Hou, Yanyan;Wang, Xiuzhen;Liu, Sanrong
    • Journal of Information Processing Systems
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    • v.12 no.3
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    • pp.502-510
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    • 2016
  • Considering video copy transform diversity, a multi-feature video copy detection algorithm based on a Speeded-Up Robust Features (SURF) local descriptor is proposed in this paper. Video copy coarse detection is done by an ordinal measure (OM) algorithm after the video is preprocessed. If the matching result is greater than the specified threshold, the video copy fine detection is done based on a SURF descriptor and a box filter is used to extract integral video. In order to improve video copy detection speed, the Hessian matrix trace of the SURF descriptor is used to pre-match, and dimension reduction is done to the traditional SURF feature vector for video matching. Our experimental results indicate that video copy detection precision and recall are greatly improved compared with traditional algorithms, and that our proposed multiple features algorithm has good robustness and discrimination accuracy, as it demonstrated that video detection speed was also improved.

Role of GSTM1 Copy Number Variant in the Prognosis of Thai Colorectal Cancer Patients Treated with 5-FU-based Chemotherapy

  • Pongtheerat, Tanett;Saelee, Pensri
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4719-4722
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    • 2016
  • Background: Glutathione S-transferase M1 (GSTM1) is involved in the detoxification of carcinogenic agents. DNA copy number variants of GSTM1 may be associated with cancer progression and may result in reduced survival time of various cancers. Determination of DNA copy number variants was here used to assess the association between GSTM1 copy number variant and pathological status and survival time of colorectal-cancer patients treated with 5-fluorouracil-based chemotherapy. Methods: One hundred thirteen Thai colorectal-cancer patients were investigated for GSTM1 copy number variant by real-time PCR. Relationships between gene copy number variants and clinico-pathological parameters were determined. Result: Associations were evident between GSTM1 copy number and stage of tumor (P = 0.026) and metastasis at diagnosis (P = 0.049), with odds ratio values of 0.2 and 0.3 respectively. Conclusions: GSTM1 copy number variant was here not related with reduced overall survival for the colorectal-cancer patients receiving 5-FU-based chemotherapy.

Copy Raising Construction in English: A Usage-based Perspective

  • Kim, Jong-Bok
    • Language and Information
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    • v.16 no.2
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    • pp.1-15
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    • 2012
  • In accounting for the so-called copy raising (CR) in English, the movement perspective has assumed that the embedded subject of the CR verb's sentential complement is raised to the matrix subject, leaving behind its pronominal copy. This kind of movement-based analysis raises both empirical and analytical issues, when considering variations in the pronominal copy constraint. This paper investigates the actual uses of the construction, using online-available corpora. Based on this corpus search, we classify two different types of copy raising predicates (genuine and perception), and discuss their grammatical properties in detail. We suggest that the simple copying rule couched upon movement operations is not enough to capture great variations in the uses of the construction, and show that interpretive constraints, e.g., perceptual characterization condition, play an important role in licensing the construction.

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Performance Evaluation of New Signatures for Video Copy Detection (비디오 복사방지를 위한 새로운 특징들의 성능평가)

  • 현기호
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.40 no.1
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    • pp.96-102
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    • 2003
  • Video copy detection is a complementary approach to watermarking. As opposed to watermarking, which relies on inserting a distinct pattern into the video stream, video copy detection techniques match content-based signatures to detect copies of video. Existing typical content-based copy detection schemes have relied on image matching. This paper proposes two new sequence matching techniques for copy detection and compares the performance with color techniques that is the existing techniques. Motion, intensity and color-based signatures are compared in the context of copy detection. Comparison of experimental results are reported on detecting copies of movie clips.

A Study on the Application of Zero Copy Technology to Improve the Transmission Efficiency and Recording Performance of Massive Data (대용량 데이터의 전송 효율 및 기록 성능 향상을 위한 Zero Copy 기술 적용에 관한 연구)

  • Song, Min-Gyu;Kim, Hyo-Ryoung;Kang, Yong-Woo;Je, Do-Heung;Wi, Seog-Oh;Lee, Sung-Mo;Kim, Seung-Rae
    • The Journal of the Korea institute of electronic communication sciences
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    • v.16 no.6
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    • pp.1133-1144
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    • 2021
  • Zero-copy is a technology that is also called no-memory copy, and through its use, context switching between the user space and the kernel space can be reduced to minimize the load on the CPU. However, this technology is only used to transmit small random files, and has not yet been widely used for large file transfers. This paper intends to discuss the practical application of zero-copy in processing large files via a network. To this end, we first developed a small test bed and program that can transmit and store data based on zero-copy. Afterwards, we intend to verify the usefulness of the applied technology in detail through detailed performance evaluation

Copy Style in Print Advertising : Focused on Humor Advertising (인쇄 광고의 카피 특성 분석 - 유머 광고를 중심으로)

  • Lee, Kwang-Sook;Koo, Ja-Hwi
    • Journal of the Korean Graphic Arts Communication Society
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    • v.27 no.1
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    • pp.73-87
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    • 2009
  • The purpose of this study is to provide a executive guideline of humor in Print advertising by analyzing the copy style. For this aim, in-depth analysis about the copy style of humor in Print advertising collected by the web-site of TV cf from 2005 to 2008 was performed. In conclusion, findings showed that the copy style in the pattern of expression was focused on the psychological arousal and incongruity and the pattern of damaging and attacking someone's prestige was considered to be significant in some degree. It was also found that the copy style of humor in Print advertising in the method of expression was focused on the factor of pun, jokes, double-meaning but the factor of satire, irony and turns of phrase was a minority.

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Improvement of Copy-Machine in terms of Human-Computer Interface and Posture Improvement of Copy-Workers (복사기의 HCI관점에서의 개선과 복사자들의 자세 개선)

  • Young-Guk Kwon;Sang-Kyu Park
    • Proceedings of the Safety Management and Science Conference
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    • 2001.11a
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    • pp.139-143
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    • 2001
  • Work-related injurieshave become the issue in the twentieth century. Musculoskeletal disorders are the most common work-related injuriesand the most frequent from of work-related i11-health (more than 50% of total work-related injuries (BLS 1990)). The workers at copy shops have complained of pain in their back, legs, and shoulders. Most of them work for more than 8 hours a day. They have claimed that their pains were associated with repetitive and continuous work over a long term. The purpose of this research is to suggest an ergonomically comfortable redesign of the copy machine. This study was performed by conducting a survey of copy shop workers who have complained of job-related physical pain, and analyzing their working postures. The copy machine was ergonomically modified to reduce the workers' pain. The VIS10N 3000 software was used to analyze the posture. The analysis showed significant difference in the ranges of back and neck motion (p<0.05).

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Mitochondrial Genome Microsatellite Instability and Copy Number Alteration in Lung Carcinomas

  • Dai, Ji-Gang;Zhang, Zai-Yong;Liu, Quan-Xing;Min, Jia-Xin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2393-2399
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    • 2013
  • Objective: Mitochondrial DNA (mtDNA) is considered a hotspot of mutations in various tumors. However, the relationship between microsatellite instability (MSI) and mtDNA copy number alterations in lung cancer has yet to be fully clarifieds. In the current study, we investigated the copy number and MSI of mitochondrial genome in lung carcinomas, as well as their significance for cancer development. Methods: The copy number and MSI of mtDNA in 37 matched lung carcinoma/adjacent histological normal lung tissue samples were examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) assays for sequence variation, followed by sequence analysis and fluorogenic 5'-nuclease real-time PCR. Student's t test and linear regression analyses were employed to analyze the association between mtDNA copy number alterations and mitochondrial MSI (mtMSI). Results: The mean copy number of mtDNA in lung carcinoma tissue samples was significantly lower than that of the adjacent histologically normal lung tissue samples (p<0.001). mtMSI was detected in 32.4% (12/37) of lung carcinoma samples. The average copy number of mtDNA in lung carcinoma samples containing mtMSI was significantly lower than that in the other lung carcinoma samples (P<0.05). Conclusions: Results suggest that mtMSI may be an early and important event in the progression of lung carcinogenesis, particularly in association with variation in mtDNA copy number.