• Journal of Gastric Cancer
• /
• v.14 no.1
• /
• pp.7-14
• /
• 2014

Endoscopic resection is the established treatment for early gastric cancer in selected patients with negligible risk of lymph node metastasis ('absolute indication'). Based on clinical observations and large pathological databases, expanding indications for endoscopic resection beyond absolute indication has been tried in Japan and Korea. However, controversies exist regarding the safety of treating early gastric cancer beyond absolute indication in terms of pathological evaluation of the resected specimen, definition of expanded indication, discrepancy between pre-endoscopic resection and post-endoscopic resection diagnoses of gastric neoplasm, and the best strategy for cases with non-curative resection. In this brief review, current evidence and clinical experience regarding issues of endoscopic resection beyond absolute indication will be summarized.

• Korean Journal of Bronchoesophagology
• /
• v.13 no.1
• /
• pp.51-54
• /
• 2007

Laryngeal trauma is an uncommon injury but can be life-threatening event. So, early diagnosis is important for appropriate surgical management and better outcome. Because there have been some controversies about Initial airway management, appropriate diagnostic evaluation, operative indication and timing, operative technique, it is difficult to make a common management pathway in laryngeal trauma. A case of laryngeal trauma with thyroid cartilage and hyoid bone fracture is presented with a brief review of literature.

• The Korean Journal of Pain
• /
• v.8 no.2
• /
• pp.331-335
• /
• 1995

Asthma is a disease of the airways that is characterized by increased responsiveness of the tracheobronchial tree to a multiplicity of stimuli. A number of causes have been postulated for the increased airway reactivity of asthma is conservative as beta-adrenergic agonist, methylxanthines, glucocorticoids, anticholinergics and mast cell stabilizing agent. Stellate ganglion block for the treatment of bronchial asthma has its controversies. Stellate ganglion block was performed for the treatment of 3 patients with bronchial asthma. After stellate ganglion blocks, dyspnea, coughing and wheezing was markedly reduced. Lung function test improved with 1 st case. Two asthma cases were able to discontinue medication for asthma. No severe aggrevation of bronchial symptoms were noted after stellate ganglion blocks. It suggested that stellate ganglion block can be safely performed on bronchial asthmatic patients.

• Advances in pediatric surgery
• /
• v.16 no.2
• /
• pp.170-176
• /
• 2010

The clinical characteristics of fistula-in-ano in infants are different from those of older children, and its treatment remains controversial. We suggest that fistula-in-ano in infants has a congenital etiology. To verify this hypothesis and to settle the controversies regarding fistula-in ano in infants, a retrospective analysis of 29 patients less than 2 years of age with anal fistulae treated between 1994 and 2009 at Samsung Changwon Hospital were reviewed retrospectively. Twenty two patients were male and mean age at diagnosis was $7.2{\pm}5.2$ months. Eleven out of 22 cases had previous surgical drainage for perianal abscess. 18 patients had fistulotomy (81.8 %) and four had fistulectomy (18.2 %). Cryptotomies with fistulectomy were performed in 10 patients (45.5 %) who had involved crypt. There was one recurrence. These results suggest that fistula-in-ano in young children less than two years of age is different from those in older children or adults. Fistulotomy is suggested to be the recommended treatment of choice. A future study involving non-operative management would be required to explore all treatment options.

• Journal of The Korean Association For Science Education
• /
• v.7 no.2
• /
• pp.89-95
• /
• 1987

Historically, one of the most famous and endless controversies in science and science education is on the origin of life. Since 1859, when the 1st edition of 'On The Origin Of Species' written by Charles Darwin had been published in London. evolutionism had the support of the public and scholars Creationists. however, argue recently that the scientific creationism is supported by the vast geological, biological, palaeontological biochemical and even astronomical evidences. Strong arguments of creationists stirred up the sharpening critiques of evolutionists. In this paper. the author summarizes three recent evolutionary critiques on creationism and refutes them from creationist view. After examing the critiques. we find that they are not based on the decisive evolutionary evidences but considerable conjectures And we show that the majority of critiques stem from the lack of communication in the academic communities.

• Journal of Yeungnam Medical Science
• /
• v.19 no.2
• /
• pp.73-91
• /
• 2002

Method of management of the spine injury should be determined, based on the status of neurological injury as well as on the presence of traumatic instability. At the thoracic and lumbar spine, patterns of neurological injury are different from the cervical spine due to their neuro-anatomical characteristics. Especially, at the thoracolumbar junction, neurological injury patterns with their respective prognosis vary from the complete cord injury or conus medullaris syndrome to the cauda equina syndrome according to the injury level. The concept of Holdsworth's instability based on the posterior ligament complex theory has evolved into the current 3-column theory of Denis. Flexion-rotation injury and fracture-dislocation are well known to be unstable that surgical fixation is frequently needed for these injuries. However, there have been some controversies for the stability of burst fractures and their treatment, such as indirect or direct decompression and anterior or posterior approach. In this article, current concepts and management of traumatic instabilities at the thoracic and lumbar spine have been reviewed and summarized.

• Journal of Arbitration Studies
• /
• v.26 no.3
• /
• pp.175-230
• /
• 2016

The controversies that have surrounded the negotiation of both the Comprehensive Economic and Trade Agreement (CETA) and the Transatlantic Trade and Investment Partnership (TTIP) have underlined the difficulties arising out from the adoption of a truly common EU investment policy. Non-governmental organizations have called into question transparency and legitimacy of international investment arbitration during the negotiations. The article presents a reflection about current developments of the EU investment policy addressing, in particular, the criticisms towards the whole investor-to-State system and the EU's efforts in developing a "tailor-made" investment agreement and Investor-to-State Dispute resolution system. Along these lines, the article critically assesses the recently announced proposal for the establishment of an 'Investment Court System' put forward by the EU during the TTIP negotiations.

• Journal of Korean Medicine for Obesity Research
• /
• v.1 no.1
• /
• pp.1-11
• /
• 2001

Obesity is a metabolic disease associated with multiple hormonal abnormalities. Therefore, obesity management aims at balancing these endocrine malfunctions nowadays. Although many studies proved interactions of hormones related with obesity, there are still lots of controversies. Most of these malfunctions are more pronounced in central, visceral obesity than in peripheral obesity. Recently, it is revealed that a central lesion of endocrine malfunction in human visceral obesity is probably related with a hypersensitivity of hypothalamopituitary-adrenal(HPA) axis. Probably associated with this axis, Insulin and cortisol promote lipid accumulation by expressing lipoprotein lipase activity, while sex hormones and growth hormone exert the opposite effects. Also reviewed was thyroid hormone which is closely related with thermogenesis. Serotonin is prescribed as antidepressant and it is applied to some eating disorders. Recently, leptin made in fat deposit also took attentions in terms of regulator of appetite and messenger of sex signal.

• Journal of Fisheries and Marine Sciences Education
• /
• v.21 no.3
• /
• pp.335-346
• /
• 2009

Offshore-aquaculture is a new idea, has emerged as an alternative method, which can minimize the damage to the natural disaster due to the environment pollution by the fish farming activities in the coast and overcome the problems of vicious cycle in fish farming management. On the other hand, as the current fish farming laws and institutions focus on the support for offshore-aquaculture, having the limit to revitalizing and supporting the fish farming business in the open sea, it is necessary to amend the laws and institutions related to fish farm. We should be establish in connection with offshore-aquaculture, after the study aims at examining the foreign laws and institutions in such countries as USA and Norway, establishing the methods for the future laws and institutions of open sea fish farm through the analysis of the issues and controversies in the process of enactment in Korea.

• Journal of Korean Foot and Ankle Society
• /
• v.17 no.4
• /
• pp.329-333
• /
• 2013

Controversies exist regarding the treatment options for the end-stage arthritic change in the lateral tarsometatarsal joints. Arthrodesis has been frequently performed, but has a disadvantage of sacrificing a mobile joint. Resection arthroplasty also gained its popularity, especially in the patients with Rheumatoid arthritis, but possible hypermobility can lead to deformity. We report a successful clinical outcome of a patient with Rheumatoid arthritis in the 4th, 5th tarsometatarsal joints treated with tendon interpositional arthroplasties.