• Women's Health Nursing
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• v.2 no.1
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• pp.138-157
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• 1996

Recently, there has been increase perception of health promotion with development of the economic state and science. Individual's responsibility and psychosocial factors have impacted on the individual's lifestyle. Health promotion can be maintained or improved through changes of lifestyle of individuals. Also, there has been supported results of health behavior health has been focused on menopausal symptom and reproductive organ. Until recently, little research has been available on the health or health care of midlife women. The purpose of this study was to explain relationship between health promoting lifestyle and hardiness, gender role characteristics. A total of 254 items of data were obtained from randomly selected subjects. The data collected from the interviews were analyzed using SPSS, yielding frequency, mean. t-test, ANOVA, Pearson Correlation, Stepwise multiple regression. The result of this study are as follows : 1) For the health promoting lifestyle, the mean score was 116.3, the highest score was nutrition(3.30) and interpersonal support(2.86), the lowest score was exercise(1.68). The highest subscale for the hardiness was committment(2.44). Also for the gender role characteristics was higher than median score(37.8). 2) There was a statistically difference the demographic variables. A total health promotion lifestyle was predicted by income and marriage satisfaction, hardiness was predicted by education, income, marriage satisfaction, support person and gender role characteristics was predicted by education. 3) With regard to the relationship among health promoting lifestyle, hardiness, gender role characteristics, the correlation coefficient between health promoting lifestyle and hardiness was r=-.48, p<.001. Also there were significant correlation between health promoting lifestyle and gender role characteristics(r=.22, p<.01), hardiness and gender role characteristics(r=-.39, p<.001). 4) A stepwise multiple regression analysis was done on the total health promoting lifestyle score using the demographic variables, hardiness subscale and gender role characteristics for independent variables. A total of 25% of the variance was explained inthe total health promoting lifestyle by the control, challenge and marriage satisfaction. In conclusion, hardiness and gender role characteristics were engaged in health promoting activity in midlife women. This study also provides new information about the health practices that midlife women report they practice. Therefore, nursing intervention to increase women's health have to be planed program that consider on the basis the results of this study.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6009-6014
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• 2014

Aims: To investigate changes in cellular immune function of patients with lung cancer before and after cytokine-induced killer (CIK) cell therapy and to identify variation effects on overall survival (OS) and progression-free survival (PFS). Materials and Methods:A total of 943 lung cancer patients with immune dysfunction were recruited from January 2002 to January 2010, 532 being allocated to conventional therapy and 411 to CIK therapy after a standard treatment according to the NCCN Clinical Practice Guidelines. All the patients were investigated for cellular immune function before and after therapy every three months. and clinical prognostic outcomes were analyzed. Results: After six courses of treatment, immune function was much improved in patients receiving CIK cells therapy as compared to controls. The percentages of recurrence and/or metastases for patients undergoing CIK cell therapy was 56.2% and 49.1% respectively but 78.6% and 70.3% among controls (p<0.001). The median OS times for CIK cell therapy and control groups were 48 and 36 months respectively. The OS rates at 12, 36, 60, 84 months in CIK treated patients were 97.8%, 66.9%, 27.7%, and 4.1% while they were 92.3%, 44.5%, 9.2%, and 1.5% in controls. OS and PFS were significantly different by log rank test between the two groups and across the three immune improvement classes. Conclusions: The immune function of lung cancer patients was improved by CIK cell therapy, associated with an increase in the OS rate and extension of the time to recurrence and/or metastasis.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4567-4570
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• 2013

Background: Nasopharyngeal carcinoma (NPC) is the commonest radiocurable cancer in Malaysia. This study aimed to determine the treatment outcomes and late effects of radiotherapy for NPC patients treated in University Malaya Medical Centre (UMMC). Materials and Methods: All newly diagnosed patients with NPC referred for treatment to the Oncology unit at UMMC from 2004-2008 were retrospectively analyzed. Treatment outcomes were 5 years overall survival (OS), disease free survival (DFS), cause-specific survival (CSS), locoregional control (LRC) and radiotherapy-related late effects. The Kaplan-Meier method was used for survival analysis and differences in survival according to AJCC stage was compared using the log-rank test. Results: A total of 176 patients with newly diagnosed NPC were treated in UMMC during this period. Late presentation was common, with 33.5% presenting with T3-4 disease, 84.7% with N1-3 disease and 75.6% with AJCC stage 3-4 disease. Radical RT was given to 162 patients with 22.7% having RT alone and 69.3% having CCRT. The stipulated OTT was 7 weeks and 72.2% managed to complete their RT within this time period. Neoadjuvant chemotherapy was given to 14.8% while adjuvant chemotherapy was administered to 16.5%. The 5 years OS was 51.6% with a median follow up of 58 months. The 5 years OS according to stage were 81.8% for stage I, 77.9% for stage II, 47.4% for stage III and 25.9% for stage IV. The 5 years overall CSS, DFS and LRC were 54.4%, 48.4% and 70.6%, respectively. RT related late effects were documented in 80.2%. The commonest was xerostomia (66.7%). Other documented late effects were hearing deficit (17.3%), visual deficit (3.1%), neck stiffness (3.1%), dysphagia (3.4%), cranial nerve palsy (2.5%), pneumonitis (0.6%) and hypothyroidism (1.2%). Conclusions: The 5 years OS and LRC in this study are low compared to the latest studies especially those utilizing IMRT. Implementation of IMRT for NPC treatment should be strongly encouraged.

• Journal of IKEEE
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• v.24 no.1
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• pp.33-39
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• 2020

In this paper, we propose the design technique of the vehicle's load weight measuring system using tire pressure, which is one of the physical elements of tires. The proposed technique consists of four processes: noise correction by load and vibration, gas flow correction, data mixer and weight conversion. Noise correction by load and vibration eliminates noise that increases the tire's internal pressure due to external shocks and vibrations produced by the vehicle while it is in motion. In the gas flow correction process, the noise of the internal pressure of the tire is increased due to the temperature rise of the ground with respect to the data obtained through the noise correction process due to the load and vibration. In the data mixer process, the load and pressure on the tolerances the empty, median and the full load are classified according to the change in pressure of the tire that is delivered perpendicular to the tire in the event of cargo. In the weight conversion process, weight is expressed by weight through weight conversion algorithms using noise correction results by load and vibration and gas flow correction. The weight conversion algorithm calculates the weight conversion factor, which is the slope of the linear function with respect to the load and pressure change, and converts the weight. In order to evaluate the accuracy of the loading weight measurement system of the vehicle using the tire pneumatic system technique proposed in this paper, we propose the design technique of the vehicle's load weight measuring system using tire pressure, which is one of the physical elements of tires.. Noise correction results by load and vibration and gas flow data correction results showed reliable results. In addition, repeated weight precision test showed better weight accuracy than the standard value of 90% of domestic companies.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.2
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• pp.203-208
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• 2006

The main research conducted previously on GPS ionosphere in China is first introduced. Besides, the current investigations include as follows: (1) GPS-based spatial environmental, especially the ionosphere, monitoring, modeling and analysis, including ground/space-based GPS ionosphere electron density (IED) through occultation/tomography technologies with GPS data from global/regional network, development of a GNSS-based platform for imaging ionosphere and atmosphere (GPFIIA), and preliminary test results through performing the first 3D imaging for the IED over China, (2) The atmospheric and ionospheric modeling for GPS-based surveying, navigation and orbit determination, involving high precisely ionospheric TEC modeling for phase-based long/median range network RTK system for achieving CM-level real time positioning, next generation GNSS broadcast ionospheric time-delay algorithm required for higher correction accuracy, and orbit determination for Low-Earth-orbiter satellites using single frequency GPS receivers, and (3) Research products in applications for national significant projects: GPS-based ionospheric effects modeling for precise positioning and orbit determination applied to China's manned space-engineering, including spatial robot navigation and control and international space station intersection and docking required for related national significant projects.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.12
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• pp.5741-5747
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• 2011

The purpose of this study was to find correlation between the Berg Balance Scale which is most commonly used and the equilibrium scores from Smart Balance Master System which is used for the test of the balance ability for the patients with chronic hemiparetic stroke to predict their falling risk though examining the postural control. Twenty-two subjects who had first stroke participated in this study. Participants were measured the Berg Balance Scale and the Smart Balance Master System. The study found that there was a significant correlation between the Berg Balance Scale and the equilibrium scores from Smart Balance Master System. And there was no significant correlation at all "eye-closed and sway of surfaces" in the 6 conditions of Smart Balance Master System and there was a significant correlation with over median in the other 5 conditions. The study was uncovered that there was no meaningful correlation between the Berg Balance Scale and "eye-closed and sway of surfaces" because chronic hemiparetic stroke patients heavily relied on their vision to maintain their balance ability and the Berg Balance Scale did not properly exam it. Thus to predict their falling risk in clinical practice for the patients with chronic hemiparetic stroke, it would be more efficient ways for us to consider all the effects of sensory organs with more than one clinical evaluation method.

• The Korean Journal of Pesticide Science
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• v.7 no.3
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• pp.198-206
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• 2003

To assess potential risk of the benzimidazole fungicides, their cytotoxicities were evaluated. Activities of LDH(Lactic dehydrogenase) in the culture fluid of CHL(chinese hamster lung) fiberoblast cell treated with 4.0, 16.0 or $32.0{\mu}g/mL$ of carbendazim for 24 hours were elevated 2.16, 2.94 and 2.64 folds compared to the control, respectively. DNA synthesis was inhibited by 45% at $2.0{\mu}g/mL$ of carbendazim. Benzimidazole fungicides showed high toxicity to cell and mitochondria of CHL cell by Giemsa and MTT (3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide) assay. $IC_{50}$ by the Giemsa assay of thiophanate-methyl, benomyl, carbendazim and captafol were over 125, 1.2, 30.0 and $0.3{\mu}g/mL$, respectively. $IC_{50}$ by the MTT assay of thiophanate-methyl, benomyl, carbendazim and captafol were over 125, 18.7, 20.4 and $2.6{\mu}g/mL$, respectively. Inhibitory concentration of cell median proliferation by SRB (sulforhodamin B) assay for thiophanate-methyl, carbendazim, benomyl, and captafol were 17.4, 5.3, 1.5 and $0.5{\mu}g/mL$, respectively. Accordingly, benzimidazole fungicides inhibited DNA synthesis, mitochondrial function, cell proliferation and induced cell necrosis.

• Asia Marketing Journal
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• v.16 no.4
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• pp.1-18
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• 2015

Assuming that not all background music in advertising function as effective retrieval cues for the advertised messages, this study proposes that we should be able to distinguish the retrieval cue effect of music from the simple ad exposure effect. This study tries to identify which specific characteristics of music are related to the retrieval cue effect. Our experiment focuses on congruency and familiarity of music as key characteristics of music which affect the effectiveness of the music's role as a retrieval cue for the advertised messages. We used four groups of subjects to test the retrieval cue effect of the background music. Each group was exposed to one of the four different types of background music and was again sub-divided into an experimental and a control group (i.e., a total of eight independent sub-groups were included in the experiment.) The first two sub-groups were exposed to the experimental advertisement with the background music of high congruency and high familiarity. After the ad exposure, the background music was provided as a retrieval cue to only one of the two sub-groups. Comparison of the memory performance between the two sub-groups will reveal the net retrieval cue effect of the music of high congruency and high familiarity. Similarly, another two sub-groups watched the same ad but with the background music of high congruency and low familiarity. Also the same ad but with the music of low congruency/ high familiarity was shown to another two sub-groups and that of low congruency and low familiarity music was to another two. Among the two sub-groups with the same music, only one group had the music cue at the memory tasks. One hundred and seventy four undergraduate students at the college of one of authors in Asia participated in the study. Their ages ranged from 18 to 24 with a median of 20. The sample was composed of 51.7 percent male subjects. They were randomly assigned to each of the eight sub-group. The results show that the music highly congruent with the advertised message facilitates the message retrieval, while the low congruency music cue does not. It was also found that the low familiarity music cue improves memory performance only when the music is perceived as congruent with the advertised message. From a theoretical and practical perspective, this study provides boundary conditions for effective retrieval and suggests that the congruent music specifically created for the ad is a more effective retrieval cue than other types of music cues.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.5
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• pp.331-337
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• 2023

In this paper, we propose a deep learning model to detect lumbar 3 (L3) CT images to determine the occurrence and degree of sarcopenia. In addition, we would like to propose an optimization technique that uses oversampling ratio and class weight as design parameters to address the problem of performance degradation due to data imbalance between L3 level and non-L3 level portions of CT data. In order to train and test the model, a total of 150 whole-body CT images of 104 prostate cancer patients and 46 bladder cancer patients who visited Gangneung Asan Medical Center were used. The deep learning model used ResNet50, and the design parameters of the optimization technique were selected as six types of model hyperparameters, data augmentation ratio, and class weight. It was confirmed that the proposed optimization-based L3 level extraction model reduced the median L3 error by about 1.0 slices compared to the control model (a model that optimized only 5 types of hyperparameters). Through the results of this study, accurate L3 slice detection was possible, and additionally, we were able to present the possibility of effectively solving the data imbalance problem through oversampling through data augmentation and class weight adjustment.

• Radiation Oncology Journal
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• v.25 no.3
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• pp.151-159
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• 2007

Purpose: The purpose of this study is to present the treatment results and to identify possible prognostic indicators in patients with locally advanced hypopharyngeal carcinoma. Materials and Methods: Between October 1985 to December 2000, 90 patients who had locally advanced stage IV hypopharyngeal carcinoma were studied retrospectively. Twelve patients were treated with radiotherapy alone, 65 patients were treated with a combination of chemotherapy and radiotherapy, and 13 patients were treated with surgery and postoperative radiotherapy with or without neoadjuvant chemotherapy. Total radiation dose ranged from 59.0 to 88.2 Gy (median 70 Gy) for radiotherpay alone. Most patients had ciplatin and 5-fluorouracil, and others had cisplatin and pepleomycin or vincristin. Median follow-up period was 15 months. Kaplan-Meier method was used for survival rate and Cox proportional hazard model for multivariate analysis of prognostic factors. Results: Overall 3-and 5-year survival rates were 27% and 17%, respectively. The 2-year locoregional control rates were 33% for radiotherapy alone, 32% for combined chemotherapy and radiotherapy, and 81 % for combined surgery and radiotherapy (p=0.006). The prognostic factors affecting overall survival were T stage, concurrent chemoradiation and treatment response. Overall 3-and 5-year laryngeal preservation rates in combined chemotherapy and radiotherapy were 26% and 22%, respectively. Of these, the 5-year laryngeal preservation rates were 52% for concurrent chemoradiation group (n=11), and 16% for neoadjuvant chemotherapy and radiotherapy (n=54, p=0.012). Conclusion: Surgery and postoperative radiotherapy showed better results than radiotherapy alone or with chemotherapy. Radiotherapy combined with concurrent chemotherapy is an effective modality to achieve organ preservation in locally advanced hypopharyngeal cancer. Further prospective randomized studies will be required.