• Anatomy and Cell Biology
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• 제56권3호
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• pp.299-303
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• 2023

The laryngopharyngeal nerve has received much less attention that the other contributions to the pharyngeal plexus i.e., glossopharyngeal and vagus nerves. Often, in descriptions and depictions, the nerve is simply labeled as the sympathetic contribution to the pharyngeal plexus. As there is such scant information available regarding this nerve, the present review was performed. Very little is found in the extant medical literature regarding the laryngopharyngeal nerve. However, based on available data, the nerve is a consistent contributory to the pharyngeal plexus and serves other adjacent areas e.g., carotid body. Therefore, a better understanding of this structure's anatomy is important for those who operate in this area. Further studies are necessary to better elucidate the true function of the laryngopharyngeal nerve.

• 대한수의학회지
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• 제64권2호
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• pp.9.1-9.7
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• 2024

Myxomatous mitral valve disease (MMVD) is a degenerative disease of the valve leaflets, causing left atrial dilatation and eccentric hypertrophy of the left ventricle by hemodynamic instability. Red cell distribution width (RDW) is a hematologic parameter that indicates the variation of red blood cell volume and size, reflecting anisocytosis. Human studies have found that anisocytosis is associated with poor prognosis in heart disease patients, and recent veterinary studies have also confirmed that the increase in RDW is associated with high mortality in MMVD patients. Medical records of 37 Maltese dogs with MMVD were retrospectively reviewed. When comparing RDW among the MMVD stage groups, there was a significant difference between stage B1, B2 and C. A significant and strong correlation between RDW and the left atrial-to-aortic ratio was identified. RDW was significantly correlated with the reticulocyte count independent of hematocrit, and the reticulocyte count exhibited a significant increase at stage C. This suggests that the congestive heart failure secondary to MMVD could be a contributory factor leading to an elevation in RDW. In conclusion, elevated RDW may associated with left atrial enlargement and progression of MMVD.

• Journal of Preventive Medicine and Public Health
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• 제53권4호
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• pp.289-292
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• 2020

Yemen has been faced with the worst cholera epidemic of modern times, with more than 1 million suspected cases and 3000 deaths at the time of writing. This problem is largely due to the longstanding civil war between pro-government forces and the Houthi armed movement, which has severely damaged already vulnerable sanitation and healthcare facilities and systems in the country. It is further compounded by a dire lack of basic amenities, chronic malnutrition, and unfavourable weather conditions. Another contributory component may be aerial transfer by cholera-infected chironomid insects. To contain the spread of cholera in Yemen, a nation-wide armistice should be negotiated, and national and local committees must be convened to coordinate efforts on the ground. Community isolation facilities with proper sanitation, reliable disposal systems, and a clean water supply should be set up to isolate and treat sick patients. The continuity of vaccination programmes should be ensured. Public health campaigns to educate local communities about good hygiene practices and nutrition are also necessary. The One Health paradigm emphasizes a multi-sectoral and transdisciplinary understanding and approach to prevent and mitigate the threat of communicable diseases. This paradigm is highly applicable to the ongoing cholera crisis in Yemen, as it demands a holistic and whole-of-society approach at the local, regional, and national levels. The key stakeholders and warring parties in Yemen must work towards a lasting ceasefire during these trying times, especially given the extra burden from the mounting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak worldwide.

• Korean Journal of Acupuncture
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• 제37권2호
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• pp.76-87
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• 2020

Objectives : Bee venom has been widely practiced in many countries around the world. The number of clinical trials and biochemical researches on bee venom has been constantly increasing. The objective of this study is to analyze the trend of research on bee venom using bibliometric approach, a quantitative analytical method. Methods : We searched articles about bee venom which were published from 2000 to 2019 from Web of Science Database. Original and review articles published in English were included and data were extracted in terms of publication year, country, journal, keywords, organizations, and authors. Trends in bee venom research were visualized using VOSviewer program. Results : 1,547 English articles about bee venom were identified and analyzed. South Korea is a main hub in the field of bee venom research. Research organizations in South Korea showed high link strength with domestic organizations as well as with international organizations. A keyword analysis showed the following three major types of studies: studies on components of bee venom, studies on allergy and immune response, and clinical research of bee venom therapy. Conclusions : This study provides a macroscopic overview of the research on bee venom. This bibliometric analysis has identified influential authors and organizations in the field on bee venom research and provides a useful guideline to researchers who are in search of contributory research topics.

• Molecules and Cells
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• 제40권4호
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• pp.271-279
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• 2017

Ran-binding protein family member, RanBP9 has been reported in various basic cellular mechanisms and neuropathological conditions including schizophrenia. Previous studies have reported that RanBP9 is highly expressed in the mammalian brain and retina; however, the role of RanBP9 in retinal development is largely unknown. Here, we present the novel and regulatory roles of RanBP9 in retinal development of a vertebrate animal model, zebrafish. Zebrafish embryos exhibited abundant expression of ranbp9 in developing brain tissues as well as in the developing retina. Yeast two-hybrid screening demonstrated the interaction of RanBP9 with Mind bomb, a component of Notch signaling involved in both neurogenesis and neural disease autism. The interaction is further substantiated by co-localization studies in cultured cells. Knockdown of ranbp9 resulted in retinal dysplasia with defective proliferation of retinal cells, downregulation of neuronal differentiation marker huC, elevation of neural proliferation marker her4, and alteration of cell cycle marker p57kip2. Expression of the $M{\ddot{u}}ller$ glial cell marker glutamine synthase was also affected in knockdown morphants. Our results suggest that Mind bomb-binding partner RanBP9 plays a role during retinal cell development of zebrafish embryogenesis.

• 한국산학기술학회논문지
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• 제15권11호
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• pp.6669-6675
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• 2014

대학에서 교수의 연구활동을 통해서 창출되는 발명은 직무발명으로서 그 발명에 대한 특허 받을 권리는 대학의 산학협력단에 승계되고, 교수는 그 대가로 정당한 보상을 받을 권리를 갖는다. 교수의 연구활동은 교수가 단독으로 수행하는 경우보다는 대부분이 학생의 직 간접적인 기여나 참여를 통해 수행된다. 대학에서 학생의 발명자 기여분은 직무발명으로 취급될 수도 있지만, 경우에 따라서는 교수의 직무발명과 달리 자유발명으로 취급될 수도 있다. 따라서 학생의 특허 받을 권리에 대한 산학협력단의 일방적인 승계는 향후 학교와 학생 간의 분쟁의 여지를 발생시킨다. 이에 본 연구에서는 학생의 발명자 기여분에 대한 처리에 있어서 전국 80개 대학의 지식재산권 관리규정을 조사한 후 문제점을 확인하고 이에 대한 바람직한 방향을 제시한다.

• 한국의료질향상학회지
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• 제24권1호
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• pp.9-22
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• 2018

Purpose: The purpose of this study is to develop the Korean root cause analysis (RCA) software that can be used to systematically investigate underlying causes for preventing or reducing recurrence of patient safety incidents. Methods: We reviewed the existing guidelines and literatures on the RCA in order to figure out the RCA process. Also we examined the existing RCA softwares for investigating patient safety incidents to design the contents and interface of the RCA software. Based on the results of reviewing literatures and softwares, we developed a draft version of the Korean RCA software that can be easily used in Korean hospital settings by RCA teams. Results: The Korean RCA software consisted of several modules, which are modules for identifying patient safety incidents, organizing RCA team, collecting and analysing data, determining contributory factors and root causes, developing the action plans, and guiding evaluation. Conclusion: The Korean RCA software included optimized RCA process and structured logic for cause analysis. Thus even beginners in RCA are expected to easily use this software for investigating patient safety incidents. As software has been developed with the public financial support, it will be distributed free of charge. We hope that it will contribute to facilitating patient safety improvement activities in Korea.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.621-626
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• 2015

Background: Smokefree laws aim to protect employees and the public from the dangers of secondhand smoke. Waterpipe premises have significantly increased in number in the last decade, with anecdotal reports of poor compliance with the smokefree law. The literature is bereft of information pertaining to waterpipe premise employees. This study aimed to opportunistically gather knowledge about the occupational health hazards associated with working in waterpipe premises in London, England. Materials and Methods: Employees from seven convenience-sampled, smokefree-compliant waterpipe premises in London were observed for occupational activities. Opportunistic carbon monoxide (CO) measurements were made among those with whom a rapport had developed. Observations were thematically coded and analysed. Results: Occupational hazards mainly included environmental smoke exposure. Waterpipe-serving employees were required to draw several puffs soon after igniting the coals, thereby providing quality assurance of the product. Median CO levels were 27.5ppm (range 21-55ppm) among these employees. Self-reported employee health was poor, with some suggestion that working patterns and smoke exposure was a contributory factor. Conclusions: The smokefree law in England does not appear to protect waterpipe premise employees from high levels of CO. Continued concerns surrounding chronic smoke exposure may contribute to poor self-reported physical and mental wellbeing.

• 한국주거학회논문집
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• 제24권6호
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• pp.199-208
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• 2013

Developing a modern Han-style design and providing support for the commercialization development model in recent years has been propelled by the Han-style Support Strategies of the central government in conjunction with Han-style revitalization related projects that reflect the efforts of local governments. Han-style revitalization, the rekindling and revaluing of human behavior and interest in local governments following the social and cultural changes of the past decades, has emerged as an increasingly traditional area of concern in Han-style design. The purpose of the study was to provide a method which clarifies the design rules of the Han-style bathroom based on an evaluation of sensibilities and a rough set theory, and to give the components meaning and to systematize the method. Essentially, the Han-style bathroom design evaluation is a complex multi-criteria decision making process that seeks to improve the effectiveness and objectively of the Han-style bathroom design. Han-style bathroom design can be displayed in a graphical representation in response to input from the evaluation concerning sensibilities. Because the graphical representation is composed of 3D data, it is possible to display the Han-style bathroom design form in any desired perspective and also to perform shading and other operations. With the proposed method, it is possible to obtain a combination of several contributory components which can be referred to as Reducts, Covering Index and Column Score. Han-Style/Non Han-Style Bathroom Designs were identified by the combination of several components.

• 한국지구과학회지
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• 제34권7호
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• pp.605-614
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• 2013

대부분의 급경사지의 붕괴는 지형적으로 불안정한 지역에서 발생한다. 백두산은 전형적인 산악 지역으로 잠재적 폭발 가능성을 지닌 활화산으로 알려져 있다. 본 연구에서는 백두산지역의 수치고도모형을 이용하여 지형요소와 선구조선 분석을 통해 재해 위험도를 작성하였다. 취약도 분석에 사용되는 요소는 지형으로부터 산정된 방위도, 경사도, 상부사면기여면적, 접선구배곡률, 윤곽구배 곡률, 습윤지수의 분포를 이용하였다. 더불어 선구조의 선밀도도를 작성하여 재해 위험도를 평가하는데 이용하였다. 지형요소를 이용한 백두산지역의 재해위험도 분석 결과 남쪽 내지 남서부 지역의 재해 위험도가 4-5등급으로 높게 나타나고 있다.