• 제목/요약/키워드: Contrast materials

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조영제 사용이 양성자 Range와 SOBP(Spread-Out Bragg peak)에 미치는 영향 (Influence of Intravenous Contrast Medium on Proton range and SOBP(Spread-Out Bragg peak))

  • 김호식;최승오;김은숙;전상민;염두석
    • 대한방사선치료학회지
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    • 제26권2호
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    • pp.183-189
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    • 2014
  • 목 적 : 조영제는 CT모의치료시 정상조직과 악성종양을 구분하는데 뛰어난 대조도를 제공하기 때문에 CT모의치료에 널리 사용하고 있다. 하지만 조영제는 치료계획 CT에서 일시적으로 존재하기 때문에, 치료계획과 실제 치료 사이에는 Hounsfield Unit(HU)의 차이가 발생하게 된다. 이에 본 연구에서는 조영제 사용으로 인한 HU의 변화가 양성자 치료계획에 미치는 영향을 확인 하고자한다. 대상 및 방법 : 20명의 간암 환자에게서 Phase에 따른 HU값의 변화를 측정하였다, 그리고 5명의 양성자치료계획에서 HU변화에 따른 Range와 Spread-Out Bragg peak(SOBP)의 변화를 살펴보았다. Hand made water phantom을 이용하여 깊이와 HU의 변화에 따른 Range와 SOBP의 변화를 확인하였다. 결 과 : 20명 간암 환자의 HU 변화(Pre contrast, Arterial phase, Porta phase)는 간 조직에서 ($58{\pm}5.7$, $75{\pm}9.5$, $117{\pm}14.6$)이었으며 대동맥에서($40{\pm}6.1$, $279{\pm}49.0$, $154{\pm}22.8$)이었다. 5명의 간암 양성자치료계획에서 HU 변화에 따른 Range 변화는 평균 2.5 mm, SOBP 변화는 평균 1.4 mm 이었다. Hand made water phantom study에서는 HU가 증가함에 따라 Range는 감소되었고 SOBP는 줄어들었다. 결 론 : 양성자 치료계획에서 HU값의 변화는 양성자 Range와 SOBP를 변화시켰다. 실제 양성자 빔에서 HU 변화에 따른 Range와 SOBP의 변화에 대한 추가적인 연구가 필요할 것으로 사료 된다.

Quantitative T1 Mapping for Detecting Microvascular Obstruction in Reperfused Acute Myocardial Infarction: Comparison with Late Gadolinium Enhancement Imaging

  • Jae Min Shin;Eui-Young Choi;Chul Hwan Park;Kyunghwa Han;Tae Hoon Kim
    • Korean Journal of Radiology
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    • 제21권8호
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    • pp.978-986
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    • 2020
  • Objective: To compare native and post-contrast T1 mapping with late gadolinium enhancement (LGE) imaging for detecting and measuring the microvascular obstruction (MVO) area in reperfused acute myocardial infarction (MI). Materials and Methods: This study included 20 patients with acute MI who had undergone 1.5T cardiovascular magnetic resonance imaging (CMR) after reperfusion therapy. CMR included cine imaging, LGE, and T1 mapping (modified look-locker inversion recovery). MI size was calculated from LGE by full-width at half-maximum technique. MVO was defined as an area with low signal intensity (LGE) or as a region of visually distinguishable T1 values (T1 maps) within infarcted myocardium. Regional T1 values were measured in MVO, infarcted, and remote myocardium on T1 maps. MVO area was measured on and compared among LGE, native, and post-contrast T1 maps. Results: The mean MI size was 27.1 ± 9.7% of the left ventricular mass. Of the 20 identified MVOs, 18 (90%) were detected on native T1 maps, while 10 (50%) were recognized on post-contrast T1 maps. The mean native T1 values of MVO, infarcted, and remote myocardium were 1013.5 ± 58.5, 1240.9 ± 55.8 (p < 0.001), and 1062.2 ± 55.8 ms (p = 0.169), respectively, while the mean post-contrast T1 values were 466.7 ± 26.8, 399.1 ± 21.3, and 585.2 ± 21.3 ms, respectively (p < 0.001). The mean MVO areas on LGE, native, and post-contrast T1 maps were 134.1 ± 81.2, 133.7 ± 80.4, and 117.1 ± 53.3 mm2, respectively. The median (interquartile range) MVO areas on LGE, native, and post-contrast T1 maps were 128.0 (58.1-215.4), 110.5 (67.7-227.9), and 143.0 (76.7-155.3) mm2, respectively (p = 0.002). Concordance correlation coefficients for the MVO area between LGE and native T1 maps, LGE and post-contrast T1 maps, and native and post-contrast T1 maps were 0.770, 0.375, and 0.565, respectively. Conclusion: MVO areas were accurately delineated on native T1 maps and showed high concordance with the areas measured on LGE. However, post-contrast T1 maps had low detection rates and underestimated MVO areas. Collectively, native T1 mapping is a useful tool for detecting MVO within the infarcted myocardium.

Low resistance and low temperature bonding between Silver and Indium

  • Cho, Sung-Il;Yu, Jin;Kim, Young-Ho
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2002년도 International Meeting on Information Display
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    • pp.275-278
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    • 2002
  • Conductive adhesives are commonly used for the interconnections of fine pitch, small packages like mobile applications. Since conductive particles connect mechanically with contact pads to give somewhat higher contact resistance, a metallurgical interconnection, which provides both fine pitch and low resistance, was studied using silver ball and indium which can be made at low temperatures. The connection resistance of the In-Ag metallurgical interconnection was lower than that of the Ni/Au-Ag mechanical interconnection and the former showed little dependency on the bonding load in contrast to the latter.

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PET/MRI에 있어 MRI 조영제가 PET에 미치는 영향 (Effect of MRI Media Contrast on PET/MRI)

  • 김재일;김인수;이홍재;김진의
    • 핵의학기술
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    • 제18권1호
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    • pp.19-25
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    • 2014
  • PET/MRI에서는 MRI의 진단적 가치를 높이기 위해 T1 조영제를 사용하고 있다. PET의 감쇠 보정을 위해 T1 시컨스 계열인 VIBE DIXON은 조영제에 직접적으로 영향을 미치지만, 실제 ${\mu}-map$과 감쇠 보정된 PET 영상에는 큰 변화가 없었다. 그러므로 PET/MRI 검사시 조영제 사용은 PET 데이터 얻기 전 후 언제든 사용할 수 있을 것이다.

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Recent Liquid Crystal Material Development for VA-TFT

  • Bremer, Matthias
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.II
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    • pp.1067-1070
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    • 2005
  • A large size flat panel LCD-TV must fulfill different requirements than a desktop LCD-monitor: The contrast must be much larger, the viewing angle should be as wide as possible and the switching times must be shorter to allow moving pictures to be displayed naturally. The "Vertically Aligned" technology is most promising to realize such a product. LC-material development for this technology began at Merck about 10 years ago. New materials based on the 1,1,6,7-tetrafluoroindane skeleton were recently synthesized via ortho-metallation and intramolecular Heck cyclization followed by an oxidative fluorination procedure. The materials offer improved properties over liquid crystals currently employed in flat panel LCD-TVs.

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Radiation effect on the corrosion of disposal canister materials

  • Minsoo Lee;Junhyuk Jang;Jin Seop Kim
    • Nuclear Engineering and Technology
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    • 제56권3호
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    • pp.941-948
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    • 2024
  • The effects of radiation on the corrosion of canister materials were investigated for the reliable disposal of high-level radioactive waste. The test specimens were gamma-irradiated at a very low dose rate of approximately 0.1 Gy/h for six and twelve months. The copper and cast iron species were less corroded when irradiated. It is hypothesized that gamma rays suppress the formation of lower-enthalpy species like metal oxides and activate reductive reactions. In contrast, it was difficult to evaluate the effect of radiation on the corrosion of titanium and stainless steel.

뇌피질 질환에서 뇌백질 신호 억제를 위한 중간시간 반전회복 영상 기법 (Medkum TAu Inversion Recover(MTIR) Sequence for White Matter Suppression in Brain Cortical Lesions)

  • 정경호;이정민;김종수
    • Investigative Magnetic Resonance Imaging
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    • 제3권1호
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    • pp.60-65
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    • 1999
  • 목적 : 뇌백질 신호억제를 위한 중간시간 반전회복(Medium Tau Inversion Recovery, MTIR)영상에서 뇌회질과 뇌배질의 대조도를 다른 기법의 MR영상과 비교해 보고 뇌피질에 이상이 있는 환자에서 MTIR영상의 유용성을 평가하고자 하였다. 대상 및 방법 : 2명의 정상 지원자와 뇌피질 이형성증을 포함한 뇌피질 질환이 있는 21명을 대상으로 뇌회질과 뇌백질의 신호의 차이를 관심영역에서 대조도 백분율과 대조도 잡음비로 츠정하여 MTIR영상과 여러 가지 다른 MR영상을 비교하였다. 또한 시각적으로 병변이 뚜렷함, 새로운 병변의 발견여부를 시각적으로 비교 평가하였다. 결과 : MTIR영상은 다른 MR영상에 비해 대조도 백분율, 대조도 잡음비가 높아 뇌회질과 뇌백질의 신호의 차이가 가장 뚜렷하였다. 신경이주이상을 포함한 21명의 뇌피질 환자에서는 MTIR영상에서 다른 영상보다 병변이 뚜려사고 병변의 묘사(delineation)을 증가 시켰으나 새로운 병변은 발견하지 못해다. 결론 : MTIR영상은 뇌회질과 뇌백질의 대조도를 증가시키는 영상 기법이며 뇌피질을 침범한 질환을 특히 뇌피질 이형성증의 병변을 매우 잘 나타냈다. 기존의 T1강조영상 또는 3D-MPRAG에서 뇌피질-백질의 구별이 어려운 경우에는 보완적으로 이용가치가 있는 영상기법으로 생각된다.

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자동노출조절장치를 이용한 흉부 방사선검사 시 갑상샘 장기선량 최소화를 위한 새로운 차폐 방법에 관한 연구 (A Study on New Shielding Method for Minimizing Thyroid Oran Dose on Chest Radiography Used Automatic Exposure Control)

  • 주영철;홍동희;한범희
    • 대한방사선기술학회지:방사선기술과학
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    • 제43권5호
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    • pp.323-329
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    • 2020
  • The purpose of this study is to investigate the effect of radiation shielding on the thyroid organ dose and image quality during Chest PA examination using automatic exposure control system. This study was conducted in the patient posture and examination conditions such as Chest PA using human model phantom. An experiment without shielding was set as a control group (non) and the cases of using paper coated with a contrast agent (contrast) and bismuth (bismuth) were used as experimental groups. Compared to non-shielded(non), the dose at bismuth increased about 7% in C(cervical vertebrae)5 and C6 and 14% in C7 and contrast showed dose increases of about 17 to 19% in C5 and C6 and about 21% in C7. As a result of the image quality comparison, when measured in the center of the cervical vertebrae, both SNR and CNR in bismuth increased about 40% higher than non, and contrast showed about 8 to 9% improvement. Compared with soft tissues of the cervix, bismuth reduced SNR by about 15% and CNR by about 13%, in contrast, SNR decreased by 11%, and CNR decreased by about 10%. In the Chest PA using AEC, the method of using the shield in front of the collimator has the advantage to observe the anatomical structure of the neck area well compared to the method using the lead. However, the dose at the neck can be increased by 7-21% depending on shielding materials.

Benefit of Using Early Contrast-Enhanced 2D T2-Weighted Fluid-Attenuated Inversion Recovery Image to Detect Leptomeningeal Metastasis in Lung-Cancer Staging

  • Kim, Han Joon;Lee, Jungbin;Lee, A Leum;Lee, Jae-Wook;Kim, Chan-Kyu;Kim, Jung Youn;Park, Sung-Tae;Chang, Kee-Hyun
    • Investigative Magnetic Resonance Imaging
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    • 제26권1호
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    • pp.32-42
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    • 2022
  • Purpose: To evaluate the clinical benefit of 2D contrast-enhanced T2 fluid-attenuated inversion recovery (CE-T2 FLAIR) image for detecting leptomeningeal metastasis (LM) in the brain metastasis work-up for lung cancer. Materials and Methods: From June 2017 to July 2019, we collected all consecutive patients with lung cancer who underwent brain magnetic resonance image (MRI), including contrast-enhanced 3D fast spin echo T1 black-blood image (CE-T1WI) and CE-T2 FLAIR; we recruited clinico-radiologically suspected LM cases. Two independent readers analyzed the images for LM in three sessions: CE-T1WI, CE-T2 FLAIR, and their combination. Results: We recruited 526 patients with suspected lung cancer who underwent brain MRI; of these, we excluded 77 (insufficient image protocol, unclear pathology, different contrast media, poor image quality). Of the 449 patients, 34 were clinico-radiologically suspected to have LM; among them, 23 were diagnosed with true LM. The calculated detection performance of CE-T1WI, CE-T2 FLAIR, and combined analysis obtained from the 34 suspected LM were highest in the combined analysis (AUC: 0.80, 0.82, and 0.89, respectively). The inter-observer agreement was also the highest in the combined analysis (0.68, 0.72, and 0.86, respectively). In quantitative analyses, CNR of CE-T2 FLAIR was significantly higher than that of CE-T1WI (Wilcoxon signed rank test, P < 0.05). Conclusion: Adding CE-T2 FLAIR might provide better detection for LM in the brain-metastasis screening for lung cancer.

광중합복합레진의 두께에 따른 투명도 차이가 수복물의 색상에 미치는 영향 (TRANSLUCENCY OF LIGHT CURED COMPOSITE RESINS DEPENDS ON THICKNESS & ITS INFLUENCE ON COLOR OF RESTORATIONS)

  • 황인남;이광원
    • Restorative Dentistry and Endodontics
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    • 제24권4호
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    • pp.585-603
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    • 1999
  • Esthetic availabilities used as an esthetic restorative maternals can be determined by the optical coincidence among materials, enamel and dentin. Enamel is highly translucent. That's why esthetic materials need to correspond the close translucency of enamel. But the translucent materials are affected by the background color. So it should be predicted that the color of estorative materials depend on the any thickness and the spectral reflectance of the background on which they are placed. The object of this investigation, under above hypothesis, was to determine and analyze how they affect the final color according to the thickness, translucency and background color (white, black and dentin) fill three commercial light cured composite resins(Charisma, Spectrum TPH and Z100). And correlation was analyzed to find out the possibility of the prediction when using the certain background color and thickness of materials. Followings are the result 1. The I shade of CHA showed the lowest contrast ratio($Co_7$) while the B3 shade of Z100 showed the highest contrast ratio(p<0.05). 2. The value of $L^*$ and $b^*$ on the white and dentin background is increased with decreasing thickness. And there are significant relationships between increasing thickness and each value(R>0.085). But there is a little change of $L^*$ and $b^*$ value on the black background regardless of the thickness(p>0.05). 3. For the $a^*$ value, there was little difference in values as a function of thickness and changed irregularly regardless of thickness in all background. 4. The pattern of increasing value of $L^*$ and $b^*$ with decreasing thickness was similar to the group of white and dentin background. In both dentin one showed lesser change of value. 5. The values of $L^*a^*b^*$ measured on the different background with same thickness showed the recognizable color difference(${\Delta}E^*$>2) when the thickness was below 2.6mm. 6. Contrast ratio was increased with increasing thickness with significant relationship (R>0.9). 7. Spectral reflectance of composite resins that calculated from Kubelka-Munk equation was showed little difference compared with observed value w1th decreasing thickness.

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