• Journal of Preventive Medicine and Public Health
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• v.30 no.3 s.58
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• pp.599-608
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• 1997

We studied on change of lens accommodation and pupil light reflex caused by VDT work in six women and compared them with those of other office works. The results were as follows. 1. In VDT work the accommodation contraction velocity decreased during the first 2-hr VDT task, then recovered markedly by the end of the one-hour lunch break, and decreased again by the end of the 2nd 2-hr VDT task. Changes of relaxation velocity showed similar pattern although it was less typical than that of contraction velocity 2. There was no marked change in accommodation contraction velocity and amplitude of accommodation in general office work and near-distance office work, and in the near-distance office work accommodation relaxation velocity decreased according to work load without recovery after lunch break. 3. Initial pupil diameter, initial pupil area of light reflex decreased significantly during VDT task only in VDT work and didn't recover after lunch break. These results suggest possibility that changes of accommodation contraction velocity, accommodation relaxation velocity, near point distance, and pupil diameter and area are useful in evaluating characteristics of VDT work. For this, more research adjusted individual differences, circadian rhythm, emotional stress needs.

• Magazine of the Korean Society of Agricultural Engineers
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• v.34 no.3
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• pp.33-42
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• 1992

The shear strength of cohesionless Soils results from particle-to-particle friction and structural resistance by interlocking. And, the shear strength of soils is subjected to vary depending on the internal states and external condtions. If the volume change occurring in the soils and stress-strain relationships under the internal and external changes can accrurately he described, it is possible to predict the behaviors of soils. To accomplish these objectives a series of drained triaxial compression tests and isotropic compression test was performed on the Banwol sand at different relative densities ranging from 20% to 80% and different confining pressures ranging from 0.4kgf/cm$^2$ to l2kgf/cm$^2$. The results and main conclusions of the study are summarized as follows; 1.When the relative density or the confining pressure is increased, the maximum deviator stress is increased. The ratio of the maximum deviator stress and the confining pressure is linearly proportional to the relative density. 2.It is observed that the dilatancy depends not only upon its relative density but also the confining stress, and that the maximum deviator stress is obtained after the diatancy occurs. 3.The volume of sands undergoes initial contraction prior to the dilatancy occurred by strain softening. The dilatancy rate eventually approaches the critical state or a constant volume. 4.At lower strains, Poisson's ratio approaches a certain minimum value regadless of the state of materials. At larger strains, however, the ratio is increased as the relative density is increased. 5.It is observed that the modulus of elasticity is linearly proportional to the relative density and the pressure. 6.When the relative density is increased, the friction angle of sands is linearly increased. 7.When the relative density is increased, the expansion index and the compression index are linearly decreased, and the ratio of the two is about 1/3.

• The Korean Journal of Physiology and Pharmacology
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• v.15 no.3
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• pp.171-177
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• 2011

Tonic smooth muscle exhibit the latch phenomenon: high force at low myosin regulatory light chains (MRLC) phosphorylation, shortening velocity (Vo), and energy consumption. However, the kinetics of MRLC phosphorylation and cellular activation in phasic smooth muscle are unknown. The present study was to determine whether $Ca^{2+}$-stimulated MRLC phosphorylation could suffice to explain the agonist- or high $K^+$-induced contraction in a fast, phasic smooth muscle. We measured myoplasmic [$Ca^{2+}$], MRLC phosphorylation, half-time after step-shortening (a measure of Vo) and contractile stress in rabbit urinary bladder strips. High $K^+$-induced contractions were phasic at both $22^{\circ}C$ and $37^{\circ}C$: myoplasmic [$Ca^{2+}$], MRLC phosphorylation, 1/half-time, and contractile stress increased transiently and then all decreased to intermediate values. Carbachol (CCh)-induced contractions exhibited latch at $37^{\circ}C$: stress was maintained at high levels despite decreasing myoplasmic [$Ca^{2+}$], MRLC phosphorylation, and 1/half-time. At $22^{\circ}C$ CCh induced sustained elevations in all parameters. 1/half-time depended on both myoplasmic [$Ca^{2+}$] and MRLC phosphorylation. The steady-state dependence of stress on MRLC phosphorylation was very steep at $37^{\circ}C$ in the CCh- or $K^+$-depolarized tissue and reduced temperature flattend the dependence of stress on MRLC phosphorylation compared to $37^{\circ}C$. These data suggest that phasic smooth muscle also exhibits latch behavior and latch is less prominent at lower temperature.

• Journal of the Korean Institute of Gas
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• v.15 no.2
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• pp.9-14
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• 2011

A set of test was conducted on a SA-372 steel for CNG storage tank to study the effect of hydrogen embrittlement. Tensile tests were carried out several conditions such as CNG, HCNG and H2 gas environment including air and Ar under the 35 MPa. Also, the test speed was set at 4*10^-4/s and 4*10^-5/s respectively. To maintain the high pressure for environmental gas during test process, we chose MTS which was installed autoclave. Test results showed that tensile stress, elongation rate and cross sectional contraction under Ar and CNG charging condition were similar to that of reference of air. And there was little bit change with test speed variations. However, hydrogen added conditions such as HCNG and H2 were revealed noticeable change in elongation rate and cross sectional contraction. Tensile stress was still uniform for all conditions. From the results, the effect of hydrogen embrittlement was confirmed on the hydrogen enriched conditions. Also its effect was showed more strong with much hydrogen concentration and slower test speed.

• Physical Therapy Korea
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• v.26 no.3
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• pp.67-75
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• 2019

Background: Stress urinary incontinence (SUI) is an involuntary leakage of urine from the urethra when intra-abdominal pressure increases, such as from sneezing, coughing, or physical exertion. It is caused by insufficient strength of the pelvic floor and sphincter muscles, resulting from vaginal delivery, obesity, hard physical work, or aging. The pelvic floor electrical stimulator is a conservative treatment generally used to relieve the symptoms of urinary incontinence. it recommended to applied before surgery is performed. Objects: The purpose of this study was to determine if the transcutaneous electrical stimulation (TCES) would be effective for the physiological symptoms and psychological satisfaction of women with SUI for an 8-weeks intervention. Methods: Easy-K is a specially designed user-friendly TCES. Five female who were diagnosed with SUI by a gynecologist but who did not require surgical intervention were included in this study. Intervention was implemented over an 8-week period. Outcome measures included vaginal ultrasonography, Levator ani muscle (LAM) contraction strength, incontinence quality of life (I-QOL), and female sexual function index (FSFI) questionnaires. Results: The bladder neck position significantly decreased across assessment time. Funneling index and urethral width significantly decreased after 8 weeks of intervention (p<.05). The bladder necksymphyseal distance and posterior rhabdosphincter thickness statistically increased and the anterior rhabdosphincter thickness showed a tendency to increase. All participants demonstrated a significant increase in the LAM contraction score across three assessment times (p<.05). Although the total score of the I-QOL did not show significant improvement, it steadily increased and among I-QOL subscales, only the "avoidance" subscale showed statistical improvements (p<.05). The total score of the FSFI statistically improved and the "desire" score significantly changed (p<.05). Conclusion: The TCES is recommended for women who want to apply conservative treatments before surgery and who have suffered from SUI in aspects of sexual function and quality of life.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.26 no.6
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• pp.1203-1208
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• 2002

LNG demand has been rapidly increasing in Korea for a variety of reasons including stable supply, non-polluting, and high combustion efficiency characteristics. As a result the construction and expansion of LNG storage facilities have been continuing at a vigorous pace. Korea Gas Corp. (KOGAS) has developed the design technology of the LNG storage tank. One of the most important structural core element of the LNG storage tank is the membrane, made by stainless steel. The membrane to be applied inside of LNG storage tank is provided with corrugations to absorb thermal contraction and expansion caused by LNG temperature. Analytical results have been performed to investigate the strength of the membrane and the reaction farce at the anchor point. Experimental studies are performed to investigate the deformation and strength of the membrane which is designed by Kogas. All experiments are conducted on the basis of RPIS, and we found the results are fully satisfied with the RPIS.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.19 no.2
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• pp.211-215
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• 2010

Continuous contraction and expansion of disk brake can be due to friction and temperature difference at repeated sudden braking. As serious vibration at disk is produced, the braking force will be changed ununiformly and braking system can not be stabilized. Temperature and heat flux at disk brake are investigated by structural and thermal analysis in this study. The maximum equivalent stress and displacement are shown respectively at the ventilated hole and the lower part of disk plate. At thermal analysis of initial state, temperature on disk plate is distributed from $95.9^{\circ}C$ to $100^{\circ}C$. The maximum heat flux of $0.0168W/mm^2$ is shown at the inner friction part between disk plate and pad. At thermal analysis of transient state, temperature on disk plate is distributed from $95^{\circ}C$ to $96.5^{\circ}C$ after 100 second. The maximum heat flux of $0.0024W/mm^2$ is also shown at the inner friction part between disk plate and pad. By comparing with initial state, the temperature on disk plate is more uniformly distributed and heat flux is more decreased by 7 times at transient state.

• Smart Structures and Systems
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• v.16 no.3
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• pp.555-577
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• 2015

In the work at hand, the development of a morphing flap, actuated through shape memory alloy load bearing elements, is described. Moving from aerodynamic specifications, prescribing the morphed shape enhancing the aerodynamic efficiency of the flap, a suitable actuation architecture was identified, able to affect the curvature. Each rib of the flap was split into three elastic elements, namely "cells", connected each others in serial way and providing the bending stiffness to the structure. The edges of each cell are linked to SMA elements, whose contraction induces rotation onto the cell itself with an increase of the local curvature of the flap airfoil. The cells are made of two metallic plates crossing each others to form a characteristic "X" configuration; a good flexibility and an acceptable stress concentration level was obtained non connecting the plates onto the crossing zone. After identifying the main design parameters of the structure (i.e. plates relative angle, thickness and depth, SMA length, cross section and connections to the cell) an optimization was performed, with the scope of enhancing the achievable rotation of the cell, its ability in absorbing the external aerodynamic loads and, at the same time, containing the stress level and the weight. The conceptual scheme of the architecture was then reinterpreted in view of a practical realization of the prototype. Implementation issues (SMA - cells connection and cells relative rotation to compensate the impressed inflection assuring the SMA pre-load) were considered. Through a detailed FE model the prototype morphing performance were investigated in presence of the most severe load conditions.

• YAKHAK HOEJI
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• v.45 no.1
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• pp.78-84
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• 2001

Heme oxygenase is a rate-limiting enzyme in heme catabolism that cleaves heme to form biliverdin, iron, and carbon monoxide. Heme oxygenase-1 is expressed in many types of cells and tissues and is highly induced in response to oxidative stress. Carbon monoxide, one of the products of heme oxygenase, can stimulate soluble guanylate cyclase and dilate the vascular smooth muscle. So, the induction of heme oxygenase by lipopolysaccharide (LPS)-induced oxydative stress and the effect of the resultant carbon monoxide on aortic contractility were examined in this study. Zinc protoporphyrine IX (ZnPP), a inhibitor of heme oxygenase, elicited weak contraction of thoracic aortic ring, and this effect was more potent in aorta of LPS-treated rats than control and was blocked by methylene blue. The hyperreactivity to ZnPP in LPS-treated group was blocked by co-treatment with aminoguanidine. In the aortic ring of LPS-treated rats, ZnPP didn't change the vasoreactivity to phenylephrine or acetylcholine. ZnPP elicited hyper-tensive effect in concious rats, and pretreatment with LPS did not affect this effect. Prazosin significantly diminished the hypertensive effect of ZnPP. These results indicate that LPS induced heme oxygenase in aotra, and the resultant carbon monoxide diminished the aortic reactivity to vasoconstrictor.

• Environmental Analysis Health and Toxicology
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• v.27
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• pp.11.1-11.8
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• 2012

Objectives: Hepatotoxicity of acetaminophen has been widely studied. However, the adverse effects on the heart have not been sufficiently evaluated. This study was performed to investigate cytotoxicity and alterations of gene expression in cultured cardiomyocytes ($H_9C_2$ cells) after exposure to acetaminophen. Methods: $H_9C_2$ cells were incubated in a 10 mM concentration of acetaminophen for the designated times (6, 12, and 24 hours), and cytotoxicity was determined by the 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide method. Alteration of gene expression was observed by microarray analysis, and RT-PCR was performed for the three representative oxidative stress-related genes at 24 hours after treatment. Results: It revealed that acetaminophen was toxic to cardiomyocytes, and numerous critical genes were affected. Induced genes included those associated with oxidative stress, DNA damage, and apoptosis. Repressed genes included those associated with cell proliferation, myocardial contraction, and cell shape control. Conclusions: These findings provide the evidences of acetaminophen-induced cytotoxicity and changes in gene expression in cultured cardiomyocytes of $H_9C_2$ cells.