• Journal of Periodontal and Implant Science
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• v.33 no.3
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• pp.373-382
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• 2003

The successful use of osseointegrated implants to replace missing teeth has been demonstrated for both the completely and the partially edentulous patients. Many studies have confirmed an excellent long-term prognosis. The successful outcome of any implant procedure is surely dependent on the interrelationship of the various components that includes the following: biocompatibility of the implant material, macroscopic and microscopic nature of the implant surface, the status of the implant bed in both a health(noninfected) and a morphologic(bone quality) context, the surgical technique, the undisturbed healing phase, the subsequent prosthetic design, and long-term loading phase. Periodontally compromised patients have poor status of the implant bed and periodontal pathogen. No longitudinal data are available whether these factors affect the prognosis of implants. In this study, 102 machined $Br{{\aa}}nemark$ implants are inserted to analyze the success rate of 1-4 years and marginal bone loss in 49 chronic periodontitis patients. The following conclusions could be drawn from this study. 1. The cumulative success rate of implants at the 4-year of loading was 95.10%. 2. 5 failed implants have been removed. One implant have been removed due to infection, two implants were removed due to failure of osseointegration. and other two implants were removed due to mechanical failure caused by over-loading. 3. Mean marginal bone loss from the time of loading was 0.94mm at first year, 1.12mm at second year, 1.25mm at third year. These results suggest that implant therapy is good treatment modality in chronic periodontitis patients, and periodontal treatment including oral hygiene program is completed prior to insertion of implants.

• Journal of the Korean Association of Geographic Information Studies
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• v.3 no.2
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• pp.73-86
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• 2000

Using monthly AVHRR-NDVI composite images, global vector data and statistical information, land cover change patterns in Asia during the major growing season (June, July and August) were analyzed for each country. Specifically, explanations on NDVI changes were developed at a regional scale emphasizing human impacts on ground vegetation. The annual mean change in each country showed NDVI-gain trends in high latitude areas and some parts of eastern China and northern/western India. On the contrary, NDVI-loss trends were distinctive in Japan, Korea, some parts of southeastern China, Vietnam, Laos, Cambodia, Thailand, Myanmar and some parts in southwestern/eastern India. These patterns largely coincided with socio-economic information reflected by human behavior. The NDVI change trends showed significant correlation with forest area changes. Also, a multiple regression model showed that the NDVI change patterns were significantly dependent on the changes in forest area and total population.

• Korean Institute of Interior Design Journal
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• v.13 no.3
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• pp.84-92
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• 2004

This study concentrates on a new idea that is formulated as a creative spatialization in contemporary architecture and painting. It is stimulated from the classical baroque, which is expressed with the conceptual instruments, 'excessive', 'decorative', 'accidential' Suggested from that, this study tries to open the actual sense area of 'the baroque' by analysing the architectural ideas of wrenching and folding by Frank O. Gehry and in the same context by elucidating the dynamic deformalising of the figures by Francis Bacon. The redefined 'new baroque' operates in the chain of the transformable and flexible images that must be recognized as 'the real' in the sense of 'the most empirical' and are vulnerable to dispersal. The typical instrument of Gehry's 'new baroque architecture' is the enclosing of the space and its folding, and Bacon, whose painting can be called as the modern baroque, takes as the expressing methods a wrenching of the figures, a relieving of the colored background against the figure and a disappearing of figures into the background. These different ideas meet in the theoretical gravitation field of the philosophy of Deleuze, in which the reconstituted baroque conception means the tension between the folds, on expansion and contraction of which the variable space is dependent, Through the general principle of 'the new baroque', a free dispersal of power, to architect and painter is offered the possibility, not only to make the real world intimate to the real life, but also to produce from there a vivid new space. Finally it brings to enjoyer and viewer the possibility, to perceive the operating power in and around oneself.

• Korean Journal of Cognitive Science
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• v.28 no.4
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• pp.223-243
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• 2017

A Hangul input method consists of two core components: key layout for primitive units (Natja), and binding rules to form more complex, composite units from primitive ones. However, careless design and implementation of an input method may result in ambiguity and inability of contiguous typing, when it comes to handle composite Hangul units. This is due to the collective nature of Hangul, namely, existence of implicit boundaries between units and syllables. This issue gets more challenging for the context-dependent 2-beolsik method, mobile environment having significantly fewer keys, and yet addition of the support for Old Hangul. For the sake of the management of complexity, we devised a system in which the binding rule is divided into two layers rather than one. Based on this concept, we implemented a tool program that, given the primitive units and their binding rules, generates input details of every composite unit and detects any potential ambiguity and conflicts. We presented the actual analysis result for Samsung Cheonji-in and KT Naratgeul, two of the most popular mobile Hangul input methods used in Korea.

• Journal of KIISE:Computer Systems and Theory
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• v.27 no.1
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• pp.68-80
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• 2000

The modern software technology toward modularization has changed the cache accessing behavior dramatically. Many modern operating systems are also departing from the past monolithic structure toward the highly modularized structure referred to as microkernel. Microkernel-based operating systems are more portable and extensible, but are likely to have worse performance. This paper quantitatively analyzes the effect of microkernel structure on cache memory to identify the primary factor for its performance degradation. Through the experiment performed on a Intel Pentium Pro processor platform, we found that the microkernel structure suffers from remarkably higher misses for L1, L2 cache and TLB than the monolithic one does. We also found that the performance of a microkernel is more dependent on the efficiency of cache memory than IPC. Finally, we found that these results come from the effect of frequent context switches mainly caused by the structural feature of a microkernel.

• BMB Reports
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• v.31 no.4
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• pp.370-376
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• 1998

Src-Homology 2 (SH2) domains have a capacity to bind phosphotyrosine-containing sequence context and play essential roles in various cellular signaling pathways. Due to the specific nature of the binding between SH2 domains and their counterpart proteins, inhibitors of SID domain binding have drawn extensive attention as a potential candidate for therapeutic agents. Here, we describe the binding assay system to screen for the ligands or blockers of the SH2 domains with an emphasis on the $p56^{lck}$ SH2 domain. In our assay system, SID domains expressed and purified as fusion proteins to Glutathione-S-transferase (GST) were covalently attached to 96-well microtitre plates through amide bond formation, which were subsequently allowed to bind the biotinylated phosphotyrosine (pY)containing synthetic pep tides. The binding of biotinylated pY peptides was detected by the horseradish peroxidase (HRP)-conjugated streptavidin. Using the various combinations of SH2 domain-pY peptides, we observed that: (1) The binding of pY-peptides to its counterpart SH2 domain is concentration-dependent and saturable; (2) The binding is highly specific for a particular combination of SH2 domain-pY peptide pair; and (3) The binding of Lck SH2-cognate pY-peptides is specifically competed by the nonbiotinylated peptides with expected relative affinity. These results indicate that the established assay system detects the SH2-pY peptide interaction with reproducible sensitivity and specificity and is suitable for screening the specific inhibitors of $p56^{lck}$ SH2 function.

• Korean Journal of Soil Science and Fertilizer
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• v.45 no.6
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• pp.928-935
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• 2012

World Agriculture faces daunting challenges in feeding the growing population today. Reduction in arable land extent due to numerous reasons threatens achievement of food and nutritional security. Under this back ground, agricultural use of acidic soils, which account for approximately 40 % of the world arable lands is of utmost important. However, due to aluminum (Al) toxicity and low available phosphorous (P) content, crop production in acidic soils is restricted. Citrus, in this context, gains worldwide recognition as a crop adapted to harsh environments. The present paper reviewed Al toxicity and possible toxicity alleviation tactics in citrus. As reported for many other crops, inhibition of root elongation, photosynthesis and growth is experienced in citrus also due to Al toxicity. Focusing at toxicity alleviation, interaction between boron (B) and Al as well as phosphorus and Al has been discussed intensively. Al toxicity in citrus could be alleviated by P through increasing immobilization of Al in roots and P level in shoots rather than through increasing organic acid secretion, which has been widely reported in other crops. Boron-induced changes in Al speciation and/or sub-cellular compartmentation has also been suggested in amelioration of root inhibition in citrus. Despite the species-dependent manner of response to Al toxicity, many commercially important citrus species can be grown successfully in acidic soils, provided toxicity alleviation Agro-biological tactics such as addition of phosphorous fertilizers are used properly.

• Journal of the Korean association of regional geographers
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• v.12 no.6
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• pp.656-670
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• 2006

In Gcochang-Gun, the population decrease, due to a rural exodus phenomenon, has led to the absolute decline in the numbers of both primary and secondary schools and students. However, the high schools in Geochang-Gun show an unusual characteristic that the students from other areas outside Geochang-Gun cover about 25% of the total students studying in Geochang-Gun. This is quite contrary to the contention that one of the major factors hindering the development of rural areas is generally the inferior condition of education. In this context, this paper aims to explore the spatio-temporal changes in the sphere of influence of the secondary education with special reference to Geochang-Gun, Gyeongnam. Most importantly Geochang High School and Geochang Daesung High School account for over 98% of the students coming from other areas outside Geochang-Gun's cross-border counties. This means that the sphere of influence of the Geochang's secondary education is dependent largely upon the two private academic high schools.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.10
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• pp.980-984
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• 2010

Exploring microRNA (miRNA) and mRNA regulatory interactions may give new insights into diverse biological phenomena. Recently, miRNAs have been discovered as important regulators that play a major role in various cellular processes. Therefore, it is essential to identify functional interactions between miRNAs and mRNAs for understanding the context- dependent activities of miRNAs in complex biological systems. While elucidating complex miRNA-mRNA interactions has been studied with experimental and computational approaches, it is still difficult to infer miRNA-mRNA regulatory modules. Here we present a novel method, termed layered hypernetworks (LHNs), for identifying functional miRNA-mRNA interactions from heterogeneous expression data. In experiments, we apply the LHN model to miRNA and mRNA expression profiles on multiple cancers. The proposed method identifies cancer-specific miRNA-mRNA interactions. We show the biological significance of the discovered miRNA- mRNA interactions.

• Journal of the Korean Operations Research and Management Science Society
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• v.38 no.1
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• pp.123-138
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• 2013

Keyword advertising has been used as a promotion tool rather than the advertising itself to online retailers. This is because the online retailer expects the direct sales increase when they deploy the keyword sponsorship. In practice, many online sellers rely on keyword advertising to promote their sales in short term with limited budget. Most of the previous researches use direct revenue factors as dependent variables such as CTR (click through rate) and CVI (conversion per impression) in their researches on the keyword advertising[14, 16, 22, 25, 31, 32]. Previous studies were, however, conducted in the context of aggregate-level due to the limitations on the data availability. These researches cannot evaluate the performance of keyword advertising in the individual level. To overcome these limitations, our research focuses on conversion of keyword advertising in individual-level. Also, we consider manageable factors as independent variables in terms of online retailers (the costs of keyword by implementation methods and meanings of keyword). In our study we developed the keyword advertising conversion model in the individual-level. With our model, we can make some theoretical findings and managerial implications. Practically, in the case of a fixed cost plan, an increase of the number of clicks is revealed as an effective way. However, higher average CPC is not significantly effective in increasing probability of purchase conversion. When this type (fixed cost plan) of implementation could not generate a lot of clicks, it cannot significantly increase the probability of purchase choice. Theoretically, we consider the promotional attributes which influence consumer purchase behavior and conduct individuals-level research based on the actual data. Limitations and future direction of the study are discussed.