• Title/Summary/Keyword: Consolidation treatment

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Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience

  • Choi, Seo Hee;Cho, Jaeho;Kim, Jin Seok;Cheong, June-Won;Suh, Chang-Ok
    • Radiation Oncology Journal
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    • v.33 no.4
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    • pp.310-319
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    • 2015
  • Purpose: Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma that is highly sensitive to radiotherapy (RT). However, the effectiveness of RT has not been well established. We reviewed our experiences to assess the role of RT for FL and analyze treatment results. Materials and Methods: Retrospective analysis was done on 29 patients who received first RT between January 2003 and August 2013. Of 23 early stage (stage I, II) patients, 16 received RT alone, four received chemotherapy followed by RT, two received RT postoperatively, and one received salvage RT for relapse after resection. Six advanced-stage (stage III, IV) patients received RT after chemotherapy: two received consolidation RT, three received salvage RT for residual lesions, and one received RT for progressive sites. Median RT dose was 30.6 Gy (range, 21.6 to 48.6 Gy). Median follow-up duration was 62 months (range, 6 to 141 months). Results: All patients showed complete response in the radiation field. Eight outfield relapses were reported. Seven patients received salvage treatment (three chemotherapy, four RT). Four patients showed excellent responses, especially to RT. Estimated 5-year and 10-year relapse-free survivals were 72% and 60%. In the RT-alone group, 5-year relapse-free survival was 74.5%. All advanced-stage patients were disease-free with 100% 5-year overall survival. Disease-specific death was noted in only one patient; four others died of other unrelated causes. No significant toxicity was reported. Conclusion: RT resulted in excellent treatment outcomes for all FL stages when used as a primary treatment modality for early stage or salvage-treatment modality for advanced-stage disease.

A Case of Delayed Diagnosis of Pulmonary Paragonimiasis due to Improvement after Anti-tuberculosis Therapy

  • Lee, Suhyeon;Yu, Yeonsil;An, Jinyoung;Lee, Jeongmin;Son, Jin-Sung;Lee, Young Kyung;Song, Sookhee;Kim, Hyeok;Kim, Suhyun
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.4
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    • pp.178-183
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    • 2014
  • Here, we report a case of pulmonary paragonimiasis that was improved with initial anti-tuberculosis (TB) therapy but confused with reactivated pulmonary TB. A 53-year-old Chinese female presented with a persistent productive cough with foul smelling phlegm and blood streaked sputum. Radiologic findings showed subpleural cavitary consolidation in the right upper lobe (RUL). Bronchoscopic and cytological examination showed no remarkable medical feature. She was diagnosed with smear-negative TB, and her radiologic findings improved after receiving a 6-month anti-TB therapy. The chest CT scans, however, obtained at 4 months after completion of anti-TB therapy showed a newly developed subpleural consolidation in the RUL. She refused pathologic confirmation and was re-treated with anti-TB medication. Nevertheless, her chest CT scans revealed newly developed cavitary nodules at 5 months after re-treatment. She underwent thoracoscopic wedge resection; the pathological examination reported that granuloma caused by Paragonimus westermani. Paragonimiasis should also be considered in patients assessed with smear-negative pulmonary TB.

Implant Removal after Percutaneous Short Segment Fixation for Thoracolumbar Burst Fracture : Does It Preserve Motion?

  • Kim, Hyeun Sung;Kim, Seok Won;Ju, Chang Il;Wang, Hui Sun;Lee, Sung Myung;Kim, Dong Min
    • Journal of Korean Neurosurgical Society
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    • v.55 no.2
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    • pp.73-77
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    • 2014
  • Objective : The purpose of this study was to evaluate the efficacy of implant removal of percutaneous short segment fixation after vertebral fracture consolidation in terms of motion preservation. Methods : Between May 2007 and January 2011, 44 patients underwent percutaneous short segment screw fixation due to a thoracolumbar burst fracture. Sixteen of these patients, who underwent implant removal 12 months after screw fixation, were enrolled in this study. Motor power was intact in all patients, despite significant vertebral height loss and canal compromise. The patients were divided into two groups by degree of osteoporosis : Group A (n=8), the non-osteoporotic group, and Group B (n=8), the osteoporotic group. Imaging and clinical findings including vertebral height loss, kyphotic angle, range of motion (ROM), and complications were analyzed. Results : Significant pain relief was achieved in both groups at final follow-up versus preoperative values. In terms of vertebral height loss, both groups showed significant improvement at 12 months after screw fixation and restored vertebral height was maintained to final follow-up in spite of some correction loss. ROM (measured using Cobb's method) in flexion and extension in Group A was $10.5^{\circ}$ ($19.5/9.0^{\circ}$) at last follow-up, and in Group B was $10.2^{\circ}$ ($18.8/8.6^{\circ}$) at last follow-up. Both groups showed marked improvement in ROM as compared with the screw fixation state, which was considered motionless. Conclusion : Removal of percutaneous implants after vertebral fracture consolidation can be an effective treatment to preserve motion regardless of osteoporosis for thoracolumbar burst fractures.

Characterization and consolidation of thermoelectric CrSi2 compound prepared by mechanical alloying (MA법으로 제조된 CrSi2 열전화합물의 평가 및 치밀화)

  • Lee, Chung-Hyo;Kim, Young
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.23 no.3
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    • pp.135-141
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    • 2013
  • Mechanical alloying was carried out to produce $CrSi_2$ thermoelectric compound using a mixture of elemental $Cr_{33}Si_{67}$ powders. An optimal milling and heat treatment conditions to obtain the single phase of $CrSi_2$ compound with fine microstructure were investigated by X-ray diffraction and differential scanning calorimetry measurement. $CrSi_2$ intermetallic compound with a grain size of 70 nm could be obtained by MA of $Cr_{33}Si_{67}$ powders for 70 hours and subsequently annealed at $650^{\circ}C$. Consolidation of the MA powders was performed in a spark plasma sintering (SPS) machine using graphite dies at $600{\sim}1000^{\circ}C$ under 60 MPa. The shrinkage of MA samples during SPS consolidation process increased gradually with increasing temperature up to $1000^{\circ}C$ and relatively significant at about $600^{\circ}C$. We tend to believe that these behaviors are deeply related to form a $CrSi_2$ compound during heating process, as can be realized from the DSC measurement. Electrical conductivity and Seebeck coefficient of sintered bodies were measured up to $900^{\circ}C$. Seebeck coefficient and power factor of $Cr_{33}Si_{67}$ compact prepared by MA and SPS at $1000^{\circ}C$ showed the maximum value of $125{\mu}V/K$ at $400^{\circ}C$ and $4.3{\times}10^{-4}W/mK^2$ at $350^{\circ}C$, respectively.

Experimental Application of Consolidants Using Artificially Weathered Stones(II): Focusing on Accelerated Weathering Test (인공풍화암을 이용한 강화제의 적용실험 연구(II): 촉진풍화실험을 통한 강화처리 암석의 내구성 평가)

  • Lee, Jae Man;Lee, Myeong Seong;Park, Sung Mi;Lee, Mi Hye;Kim, Jae Hwan
    • Journal of Conservation Science
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    • v.29 no.3
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    • pp.249-259
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    • 2013
  • This study was experimented on accelerated weathering test using salt and freeze-thaw to prove effects of consolidants and consolidation for stone cultural heritage. The samples used four kinds of stones (Gyeongju Namsan Granite, Iksan Granite, Yeongyang Sandstone and Jeongseon Marble) which to distributed by three type of weathering grade (Fresh, Weathered Stone and Highly Weathered Stone) added for thermal treatment. The samples were treated with three consolidants (Wacker OH 100, Remmers KSE 300 and 1T1G), and tested by 500 cycles with freezing-thawing and 50 cycles of salt weathering test. As a results of freezing-thawing test, the crack and destruction occurred from some samples. And total immersed samples maintained effect of consolidation to 200 cycles. Also, The rock particle was fall off and gradually destructed by salts weathering test. The consolidated sample relatively had fewer changes by the weathering than not treated sample. The sprayed sample had not continuous effect on weathering.

Estimation of Consolidation Characteristics of Soft Ground in Major River Mouth (주요 강하구 연약지반의 압밀 특성 평가)

  • Lee, JunDae;Kwon, YoungChul;Bae, WooSeok
    • Journal of the Korean GEO-environmental Society
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    • v.20 no.2
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    • pp.69-79
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    • 2019
  • The coastal area forms various sedimentary layers according to the environmental conditions such as the topography and geological features of the upper region of the river, ocean currents, and river mouth. Therefore, identifying the characteristics of the marine clay deposited in the coastal area plays a key role in the investigation of the formation of soft ground. In general, alluvial grounds are formed by a variety of factors such as changes in topography and natural environment, they have very diverse qualities depending on the deposited region or sedimentation conditions. The most important thing for the construction of social infrastructures in soft ground areas is economical and efficient treatment of soft ground. In this study, the author collected data from diverse laboratory and field tests on five areas in western and southern offshore with relatively high reliability, and then statistically analyzed them, thereby presenting standard constants for construction design. Correlation between design parameters such as over consolidation ratio, preconsolidation pressure was analyzed using linear and non-linear regression analyses. Also, proposed distribution characteristics of design parameters in consideration of each region's uncertainty through statistical analyses such as normality verification, outlier removal.

Surgical Treatment of Acute Necrotizing Klebsiella Pneumonia -Two cases report- (급성 괴사성 클렙시엘라 폐렴의 외과적 치료 -2례 보고-)

  • 류경민;김삼현;박성식;류재욱;최창휴;박재석;서필원
    • Journal of Chest Surgery
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    • v.32 no.5
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    • pp.484-488
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    • 1999
  • Massive lung gangrene is a rare but very rapidly progressing fatal complication of lobar pneumonia. Etiologic agents are Klebsiella pneumoniae, Pneumococcus and Aspergillus, etc. Chest X-ray shows firm consolidation of the involved pulmonary lobe and bulging fissure due to the volume expansion of involved lung. CT-scan shows extensive lung parenchymal destructions with multiple small cavitary lesions. Recommended treatment is the early surgical intervention combined with antibiotics. Without surgical intervention, lung gangrene is known to progress toward sepsis, multiorgan failure, and high mortality. We report two cases of rapidly progressing massive lung gangrene by Klebsiella pneumonia treated by the resectional surgery.

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Treatment for Brachymetatarsia by Callotasis (가골 신연술을 이용한 단중족증의 치료)

  • Park, Yong-Wook;Yoo, Jung-Han;Park, Hong-Jun;Cho, Yang-Bum;Yu, Sun-O;Kim, Wan-Hong
    • Journal of Korean Foot and Ankle Society
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    • v.6 no.1
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    • pp.73-79
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    • 2002
  • Purpose: To evaluate the effectiveness of callotasis using the external fixator for the treatment of brachymetatarsia. Materials and Methods: Eleven patients(15 cases) who underwent callotasis were available. Follow-up averaged 23 months(15-38 months). Both the patients' postoperative satisfaction and the postoperative radiographic results were retrospectively evaluated. Results: The duration from applying the external fixator to remove averaged 15 weeks (8-21 weeks). We did osteotomy again in two cases because of early consolidation at the osteotomy site during distraction period. All cases were evaluated mild claw toe deformity and motional pain in metatarsophalangeal joint, but all patients satisfied the postoperative results except one complained motional pain and stiffness in metatarsophalangeal joint. The metatarsal shortening averaged 13mm(9-18mm) before operation. The amount of distraction for shortened metatarsals averaged 15mm(5-22mm). We found the 6 cases of narrowing of the metatarsophalangeal joint, 2 cases of subluxation of the metatarsophalangeal joint. Conclusion: We think that callotasis with external fixator is good operative method for the brachymetatarsia.

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Maxillary Anterior Segmental Distraction with Rigid External Device: Case Report (구순구개열환자의 상악 전방분절 골신장술식을 이용한 교정 치험례)

  • Yoo, Seong-Hun;Choi, Hye-Young;Yu, Hyung-Seog;Baik, Hyoung-Seon;Cha, Jung-Yul
    • Korean Journal of Cleft Lip And Palate
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    • v.14 no.1_2
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    • pp.19-28
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    • 2011
  • Maxillary anterior segmental distraction osteogenesis (DO) has been the alternative treatment option for patients with midfacial retrusion. The patient showed unilateral cleft lip and palate, and premaxillary distraction with rigid external device (RED) was planned to solve midface deficiency and to create alveolar space. Significant advancement of A point was observed, but relapse of A point was detected during consolidation period. The vertical position of the ANS was found to have moved downward. Axis of upper incisor decreased after DO. Maxillary anterior segmental DO is effective for treatment of patient with cleft lip and palate. The alveolar space is regained successfully, and the facial profile is improved without velopharyngeal problems.

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Quantitative Evaluation for Effectiveness of Consolidation Treatment by Using the Chemical of Ethyl Silicate Series for the Sandstone in Yeongyang (영양 사암을 대상으로 한 에틸실리케이트 계열 처리제의 강화효과 평가)

  • Lee, Jang-Jon;Han, Min-Su;Song, Chi-Young;Jun, Byung-Kyu;Do, Min-Hwan
    • 보존과학연구
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    • s.30
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    • pp.125-136
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    • 2009
  • Stone cultural heritages in Korea have a severe damages from chemical and biological weathering because most of them have been situated in outdoors without any suitable protection systems, and this in turn causes deformation and structural damage. To counteract these problems and increase durability, various kinds of conservation materials are used in the conservation and restoration treatments. However until now there are not many practical and technological experiments on this subject. This paper attempts quantitative evaluation of effectiveness about chemical of ethylsilicate based resin for sandstone in Yeongyang-gun. It takes a long time to evaluate durability and side effect after conservation materials treatment. So we use artificial weathering through freezing§ thawing experimental method. As a result of this experiment, porosity and absorptance increased, and elastic wave speed, elastic modules, unconfined compression strength and tensile strength decreased more than before. This study plans to make a scientific method study about weathering factor and mechanism, and to deduce correlation between artificial weathering and natural weathering.

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