• 한국콘텐츠학회논문지
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• 제22권7호
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• pp.663-669
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• 2022

본 연구는 세치제에 함유되어지는 불소의 함유량이 1500ppm이하로 상향됨에 따라 시판되어지는 세치제의 불소 함유량도 향상되었다. 이에 따라 인체에 노출되어지는 불소의 양을 예측하고 이를 소비자에게 제공하여 안전한 세치제의 사용에 대한 대안을 제시하는데 목적이 있다. 본 연구는 2021년 3월부터 2주간 1300명을 대상으로 일반적 특성과 구강건강행위를 설문조사하였다. 조사한 결과를 ConsExpo Web 1.0.2. 노출평가하기 위한 입력변수로 사용하였다. 그 결과 불소가 1500ppm함유된 세치제를 사용할 경우남자는 External dose on day of exposure가 2.3×10-2 mg/kg/day, 여자의 경우 2.9×10-2 mg/kg/day, 2-3세 아동은 7.3×10-2 mg/kg/day로 추정되었다. 본 연구결과 시중에 유통되어지는 세치제의 불소함유량이 증가됨에 따라 소비자들의 안전한 사용을 위한 기준을 제시하는데 기초자료로 사용될 것이라 사료되어진다.

• 한국환경보건학회지
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• 제50권1호
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• pp.43-53
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• 2024

Background: Exposure assessment is an important part of risk assessment for consumer products. Exposure models are used when estimating consumer exposures by considering exposure routes, subjects, and circumstances. These models differ based on their tiers, types, and target populations. Consequently, exposure estimates may vary between models. Objectives: This study aimed to compare the results of different exposure models using identical exposure factors. Methods: Chemical exposure from consumer products was calculated using four consumer exposure assessment models: Targeted Risk Assessment 3.1, Consumer Exposure Model 2.1 (CEM), ConsExpo web 1.1.1, and the Korean Exposure Algorithm (primary and detailed) issued by the Ministry of Environment, No. 972 (MOE). The same exposure factors were used in each model to calculate inhalation and dermal exposures to acetaldehyde, d-limonene, and naphthalene in all-purpose cleaners, leather coating sprays, and sealants. Results: In the results, TRA provided the highest estimate. Generally, MOE (detailed), CEM and ConsExpo showed lower exposures. The inhalation exposure for leather coating spray showed the largest differences between models, with differences reaching up to 1.2×10⁷ times. Since identical inputs were used for the calculations, it is likely that the models significantly influenced the estimated results. Conclusions: Despite using the same exposure factors to calculate dermal and inhalation exposures, the results varied substantially based on the model's exposure algorithm. Therefore, selecting an exposure model for assessing consumer products should be done with careful consideration.

• 한국환경보건학회지
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• 제50권4호
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• pp.237-256
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• 2024

Background: Human health and environment exposure assessments of chemicals are essential part for REACH and BPR as well as K-REACH and K-BPR. Several useful exposure assessment tools have been developed and updated to become extensively used during more than fifteen years of chemical registrations under REACH and their updates are still going on. Objectives: Evolution of regulatory tools for environment, workers and consumers exposure assessments under REACH is investigated focusing on why and how tools have been developed and updated for the future regulatory tools in Korea. Methods: REACH regulatory tools including EUSES, ECETOC TRA and CHESAR as well as built-in models SimpleTreat and SimpleBox were chosen with other frequently used Tier 1 and 2 tools. Available resources such as homepage information, background documents, related scientific reports, relevant journal publications, up-to-date lists of new version publications, release notes and user guides were reviewed extensively and summarized using easy-readable Tables and Figures. Results: SimpleTreat and SimpleBox are built-in models both for EUSES and ECETOC TRA (Environment). ECHA's CHESAR contains ECETOC TRA (Workers) and ECETOC TRA (Consumers) as well as EUSES and ECETOC TRA (Environment) for environment exposure assessment while results of Tier 2 Stoffenmanager and ConsExpoWeb can be imported. Evolution of CHESAR from version 1 (2010) to 3.8 (2023) has focused on the compatibility of frequent updates of IUCLID, importing functionality, editability, updated use maps, harmonised conditions of use as well as updates of the built-in tools evolved according to scientific development, refinements of the tool, increased conservatism and user-friendliness. CHESAR Platform 1.0 will soon be published to serve both for REACH and BPR. Conclusions: Updates of the tools can be successfully continued by transparency of the tools, participation of industry sectors for tool refinements and tool developers'/authorities' encouragements of partners/users to jointly innovate tools through scientific researches, tool validations and user feedback.