• Archives of Plastic Surgery
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• 제35권3호
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• pp.321-324
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• 2008

Purpose: Lymphoma originated from mucosa associated lymphoid tissue(MALT) is most common in gastrointestinal system, and rarely found in salivary gland, thyroid, bronchus or orbit. We experienced a case of MALT lymphoma which was originated from conjunctiva and involving lower eyelid without metastasis. Methods: A 40-year-old man suffered palpable mass on right lower eyelid without pain. Orbital computed tomographic and ultrasonographic findings showed a conical mass($1.9{\times}1.2{\times}0.9cm$ size) inside lower eyelid. The mass was completely excised under local anesthesia and histopathological examination was followed. Results: Microscopic finding showed a multiple follicular colonization. In the follicle, small lymphocytes and plasma cells differentiated to centrocyte-like cell, monocyte B cell, plasma cell were diffusely infiltrated. Immunophenotyping was preformed on fixed section. The majority of the small cells were immunoreactive for the B cell marker CD20. Based on the typical histological findings supported by immunostaining, the mass was defined as MALT lymphoma. After excision, SPECT, abdominal CT was carried out and there were no evidence of extraorbital disease. Conclusion: Biopsy and pathological examination should be performed in patients who complain palpable mass on lower eyelid because of possibility of MALT lymphoma. Although MALT lymphoma is rarely metastasized, it is necessary to evaluate the extraorbital involvement using SPECT or other radiologic exams. For detecting extraorbital involvement, periodic follow-up examination is need.

• Archives of Plastic Surgery
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• 제32권2호
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• pp.219-226
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• 2005

Muller's muscle-levator aponeurosis advancement procedure was performed to correct mild to moderate congenital blepharoptosis with moderate to good levator function and to correct severe aquired blepharoptosis with poor levator function. Through the blepharoplasty incision, the upper half of the tarsal plate was exposed and the orbital septum was opened to show the levator aponeurosis. The Muller's muscle was dissected from the superior margin of the tarsal plate and from the posteriorly located conjunctiva with sharp scissors. The Muller's muscle and levator aponeurosis were advanced on the anterior surface of the tarsal plate as a composite flap and fixed approximately 3 to 4 mm inferior to the upper edge of the tarsal plate with three horizontal 6-0 nylon mattress sutures. The amount of advancement of the composite flap was controlled by the location of the upper eyelid margin 2 mm below the upper limbus in primary gaze after the first suture in the middle portion of the flap. The excess flap was trimmed off with scissors, but trimming was usually not necessary in cases of mild to moderate ptosis. Nine cases underwent this Muller's muscle-levator aponeurosis advancement procedure from September 2003 to September 2004. Five cases were congenital blepharoptosis with 2-4 mm ptosis and more than 5 mm of levator function, but three of the four acquired ptosis cases had more than 4 mm ptosis with poor levator function. The age of the patients ranged from 7 to 81 years. In operative results, all patients except one traumatic case were within 1 mm of the desired eyelid height in primary gaze. This procedure can provide not only tightening of the Muller's muscle but also advancement and firm fixation of the levator aponeurosis to the tarsal plate, yielding predictable results.

• 한국안광학회지
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• 제9권1호
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• pp.135-143
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• 2004

우리 몸은 연령의 증가에 따라 눈과 시력에 노화가 나타난다. 본 연구에서는 안구의 연령에 따른 변화를 노인들을 대상으로 조사하여 연령의 증가에 따른 전안부와 후안부 대한 해부생리학적 변화를 고찰하고자 한다. 광주지역 50-79세 사이의 노령자 219명을 대상으로 문진, 외안부 검사, 시력검사, 눈꺼풀 틈새의 높이와 넓이, 가시홍채직경, 동공크기 등을 측정하였다. 연령의 증가에 따라 50대 이상에서는 눈꺼풀 결막, 각막, 전안방, 홍채, 수정체, 유리체, 맥락막, 망막 및 신경, 암순옹, 대비감도, 굴절이상 등에서 변화가 나타남을 알 수 있다. 눈꺼풀 틈새의 높이와 넓이는 연령의 증가로 젊은이 보다 좁아 졌으나 각막의 수평직경은 거의 변화가 없는 것으로 조사되었다. 따라서 노인의 안구와 시력에 대한 해부생리학적인 정확한 이해가 있어야 노인환자의 안경처방이나 시력관리를 완벽하게 할 수 있을 것으로 사료된다.

• 한국안광학회지
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• 제5권1호
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• pp.73-81
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• 2000

본 연구는 안경원이나 안과에 내원한 환자의 문진에서 반드시 알아두어야 할 알코올과 약물이 눈과 콘택트렌즈에 미치는 영향을 이해하기 위해 수행하였다. 전신질환이나 국소 이상으로 복용하는 약물, 연고, 점안액 등이 눈의 건강 특히 시력에 미치는 영향과 콘택트렌즈 착용에 미치는 영향을 고찰하였다. 점안약을 제외한 경구투여 약물은 대부분 동공에 변화를 일으키며 누액생산의 감소, 황반이나 망막이상, 시신경 이상 등을 유발하고 점안약은 주로 각막과 결막에 영향을 마치는 것으로 알려지고 있다. 가장 많이 사용되는 안과용 약물은 스테로이드인데 상대적으로 부작용이 많으므로 신중을 기해야한다. 알코올을 섭취하면 탈수 현상과 영양부족 그리고 산동제로서 역할을 하여 나안 시력과 교정시력 저하, 복시, 암순응 불량, 글레어 Glare 회복시간 지연, 입체감 감소, 파랑-노랑 또는 적-녹색 손상, 시력의 환상 상태 등이 나타난다. 정상적인 순목과 누액 구성 성분이 적당하면 콘택트렌즈 착용을 성공적으로 할 수 있으나 빈번한 약물투여가 정상적인 기능을 방해하므로 정확히 문진하여 약물과 콘택트렌즈 관계를 고려해야 한다. 전신 또는 국소 투약이 소프트렌즈 착용과 변색에 미치는 영향 그리고 소프트렌즈는 약물의 저장소 역할을 하므로 방부제의 독성 및 알레르기 반응도 고려해야 성공적으로 콘택트렌즈를 착용할 수 있다. 또한 콘택트렌즈로 인한 염증성 반응을 치료하기 위해 Corticosteroid 와 non-steroidal anti-inflammatory drugs(NSAIDs)가 이용되는데 스테로이드는 효과가 뛰어나지만 부작용이 많으므로 단기간 투여해야 한다.

• 한국안광학회지
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• 제2권1호
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• pp.85-90
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• 1997

안구의 각막과 결막은 외계에 노출되어 있어서 손상을 받기 쉽고, 손상부위에 병균이 감염되면 염증이 유발되어 심한 시력장애를 초래하기도 하는데, 누액 속에 포함되어 있는 lysozyme은 이러한 병균에 대해 항균작용을 가지므로 평소에는 안구가 노출되어 있어도 각 결막염이 발생하지 않는다. 본 연구는 lysozyme의 항균효과를 조사하고자 각 결막염의 원인균 중 5가지를 선별하여 배양하였고, 그 배양액에 lysozyme을 농도별로 첨가하면서 생육저해 정도를 측정하였다. 그 결과, 배지 중의 lysozyme 농도가 증가할수록 공시균의 생육은 저해되었다. 1mM 농도의 lysozyme에 의해 Pseudomonas는 43%, Neisseria는 41%, KlebsielIa는 35%, Staphylococus는 22% 생육이 저해되었고, 그람음성균은 그람양성균인 Staphylococus보다 lysozyme에 대한 감수성이 약 1.5~2.0배 큰 것으로 나타났다. 그러나 lysozyme은 진균인 Fusarium의 생육에는 매우 미약한 저해양상을 나타내었다.

• 한국임상수의학회지
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• 제33권4호
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• pp.228-230
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• 2016

An 1-year-old, spayed, female Labrador Retriever was presented for bilateral epiphora. A complete ophthalmic examination was conducted, including Schirmer tear test, rebound tonometry, fluorescein staining, slit lamp biomicroscopy, and binocular indirect ophthalmoscopy. To determine the patency of the nasolacrimal duct system, a nasolacrimal flush and dacryocystorhinography were also performed. Although the nasolacrimal flush showed patency in the upper and lower lacrimal puncta in both eyes (OU), the lower lacrimal puncta were not found in the original palpebral conjunctiva, but on medial canthal skin with very small opening. Moreover, the nasolacrimal ducts in OU were not patent with flushing. Bilateral nasolacrimal duct atresia was confirmed by dacryocystorhinography. No other abnormalities of the eyes were found on complete ophthalmic examinations. Bilateral congenital anomalies of the lower lacrimal puncta and nasolacrimal duct atresia were diagnosed in this dog.

• 대한수의학회지
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• 제26권1호
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• pp.11-17
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• 1986

The arterial supply to the eyeball of the Korean native goat has been described. Observations were made by dissection of ten Korean native goats fixed in embalming fluid and injected with neoprene latex. The results were as follows. 1. The eyeball and accessory ocular organ of the Korean native goat received its blood supply chiefly from the A. ophthalmica externa and partly from the branches of A. temporalis superficialis and A. malaris. 2. A. ophthalmica externa formed Rete mirabile ophthalmicum after giving off Ramus muscularis and A. lacrimalis, and continued to A. supraorbitalis. 1) A. lacrimalis was given off between Mm. rectus lateralis and dorsalis, and supplied lacrimal gland. 2) Rete mirabile ophthalmicum gave off A. ciliares posteriores longae and Rami musculares. A. ciliates posteriores longae gave off A. ciliates posteriores medialis and lateralis, Ramus anastomoticus cum A. ophthalmica interna, A. centralis retinae, Aa. ciliares posteriores breves and Aa. episcaeralis. Rami musculares supplied to M. rectus dorsalis, M. obliquus dorsalis, M. retractor bulbi, M. levator palpebrae superioris and M. rectus medialis, and continued Aa. ciliares anteriores after giving off A. episclerales and A. conjunetivales. 3) A. supraorbitalis supplied to M. rectus dorsalis. M. obliquus dorsalis and conjuntiva, and passed into supraorbital foramen. 3. A. malaris gave off A. palpebrae tertiae, A. palpebralis inferior medialis and A. palpebralis superior medialis, which supplied to third eyelid, medial aspect of the eyelids and conjunctiva. 4. A. temporalis superficialis gave off A. palpebralis inferior lateralis and A. palpebralis superior lateralis, which supplied to lateral aspect of the eyelids, M. orbicularis oculi and M. frontoscutularis.

• 대한두개안면성형외과학회지
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• 제17권3호
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• pp.119-127
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• 2016

Background: Conventional correction of malunioned zygoma requires complete regional exposure through a bicoronal flap combined with a lower eyelid incision and an upper buccal sulcus incision. However, there are many potential complications following bicoronal incisions, such as infection, hematoma, alopecia, scarring and nerve injury. We have adopted a zygomaticofrontal suture osteotomy technique using transconjunctival incision with lateral paracanthal extension. We performed a retrospective review of clinical cases underwent correction of malunioned zygoma with the approach to evaluate outcomes following this method. Methods: Between June 2009 and September 2015, corrective osteotomies were performed in 14 patients with malunioned zygoma by a single surgeon. All 14 patients received both upper gingivobuccal and transconjunctival incisions with lateral paracanthal extension. The mean interval from injury to operation was 16 months (range, 12 months to 4 years), and the mean follow-up was 1 year (range, 4 months to 3 years). Results: Our surgical approach technique allowed excellent access to the infraorbital rim, orbital floor, zygomaticofrontal suture and anterior surface of the maxilla. Of the 14 patients, only 1 patient suffered a complication-oral wound dehiscence. Among the 6 patients who received infraorbital nerve decompression, numbness was gradually relieved in 4 patients. Two patients continued to experience persistent numbness. Conclusion: Transconjunctival incision with lateral paracanthal extension combined with upper gingivobuccal sulcus incision offers excellent exposure of the zygoma-orbit complex, and could be a valid alternative to the bicoronal approach for osteotomy of malunioned zygoma.

• 한국환경과학회지
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• 제26권2호
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• pp.249-256
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• 2017

In this study, we evaluated the potential of 70% ethanol extract from Persicaria nepalensis (PNE) as a cosmetic ingredient by primary skin irritation, ocular irritation, and maximization tests for delayed hypersensitivity in New Zealand white rabbits and Hartley guinea pig. Skin safety study was performed to evaluate the potential toxicity of PNE using the primary irritation test. In the primary irritation test, 50% PNE was applied to the skin, and no adverse reactions such as erythema and edema were observed at the intact skin sites. Therefore, PNE was classified as a practically non-irritating material based on a primary irritation index of "0.0.". In the ocular irritation test, the 50% PNE applied did not show any adverse reactions in the different parts of rabbit eyes, including the cornea, iris, and conjunctiva. Thus, PNE was classified as a practically non-irritating material based on an acute ocular irritation index of "0.0.". Skin sensitization was tested by the Guinea Pig Maximization Test (GPMT) and Freund's Complete Adjuvant (FCA) using an intradermal injection of 10% PNE. Edema and erythema were not observed 24 and 48 h after the topical application of PNE in skin sensitization test, which exhibited a sensitization score of "0.0.". Therefore, it can be suggested that P. nepalensis could be used as potential candidates for cosmoceutical ingredients, without any major side effects.

• Archives of Plastic Surgery
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• 제40권4호
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• pp.409-413
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• 2013

Background Buried non-incisional double-eyelid blepharoplasty is a popular aesthetic procedure. Although various modified continuous suture techniques have been used to create a more natural appearance and to reduce downtime, complications such as loosening of the double fold, asymmetry, and foreign body reactions have been observed. Methods This study included 250 patients who underwent double-eyelid blepharoplasty between March 1997 and November 2012 using a modified single-knot continuous buried non-incisional technique. With 4 stab incisions in the upper eyelids, one of two needles loaded with double-armed 7-0 nylon was passed in one direction alternately through the dermis and the conjunctiva, while the other needle was passed subconjunctivally in the opposite direction. Both ends of the sutures were knotted within a lateral stab incision of the upper eyelids and were buried in the orbicularis oculi muscle. Results Most patients displayed satisfactory aesthetic results, and no significant complications occurred. There was no obvious regression of the double fold; however, 3 patients required reoperation to correct loosening of the fold on one side during the follow-up period. One patient presented with the suture knot subcutaneously, and the knot was removed in the clinic. Conclusions The modified single-knot continuous buried non-incisional technique is a simple and less time-consuming method for a durable double fold and provides satisfactory aesthetic results.