• Journal of Korean Society of Transportation
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• v.30 no.3
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• pp.7-15
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• 2012

Korean Highway Capacity Manual (KHCM) has been used when we analyze the pedestrian Level of Service (LOS) of a pedestrian facility. However, the pedestrian LOS by KHCM is largely insensitive to pedestrian congestion levels. The objective of this study is to identify the source of this problem within the KHCM calculation method, and to propose an improved method using the case study from Seoul. Based on KHCM results, the pedestrian LOS is A for more than 90% of the Seoul region, which seems to be unrealistic. On the other hand, this study includes an effective adjustment parameter using the absolute value of effective sidewalk width. Using this method, results shows some changes including newly identified areas of LOS C and LOS D. The analysis of pedestrian LOS is carried out for the entire metropolitan region of Seoul in order to evaluate area wide pedestrian level of service in Seoul.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.46 no.2
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• pp.108-115
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• 2020

Objectives: Kinesiology tape (KT) creates a pulling force on the skin, thus improving blood and lymph flow by alleviating hemorrhage and congestion of lymphatic fluid. The authors hypothesized that the use of KT could be beneficial for the management of complications after head and neck surgery and designed this study to evaluate the effects of KT on swelling, pain, and trismus after enucleation of mandibular dentigerous cysts with third molar extraction. Materials and Methods: Forty patients who underwent enucleation of a dentigerous cyst with extraction of the mandibular third molar were selected. The patients were randomized into two groups (n=20 each): a KT group, where KT was applied after surgery in addition to basic postoperative care, and a control group, where patients received basic postoperative care without KT application. Swelling, pain, and trismus were evaluated before surgery (T0) and on postoperative days 1 (T1), 2 (T2), and 3 (T3). Cyst volume, gauze weight for assessing bleeding, and operation time were recorded. Results: There was a significant difference between the two groups in the change in swelling up to T1 and the change in swelling between T1 and T2. The maximum swelling in the KT group was significantly less than that in the No-KT group and maximum swelling appeared faster in the KT group than in the No-KT group. Both groups showed a mild pain response but there was no significant difference between the two groups. There was no significant difference on interincisal distance change between the two groups. There were no correlations between cyst volume, bleeding, operation time, and maximum swelling. Conclusion: KT can effectively manage facial swelling after oral and maxillofacial surgeries such as cyst enucleation and third molar extraction, thus improving postoperative patient satisfaction levels and quality of life.

• Journal of the Korea Society for Simulation
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• v.17 no.3
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• pp.63-73
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• 2008

The aim of study is to analyze the berth occupancy rate according to the ship size. P Iron and steel company operate exclusive bulk terminal at P port and G port and the depth of water at berth are not so equal each other. And to reduce the sea transport cost between loading port and unloading port P and G, P company increases the number of large ship while ship scheduling. But it causes to increase the berth congestion at the specific water depth berth owing to the draught of large ship. At this point, usually ship waiting time starts to rise even at low levels of berth occupancy rate, and will rise more and more sharply at the level of full utilization. But it is not common at exclusive terminal like P port and G port. Bulk ships arrive at port according to the early planned arrival time and the coefficient of variation of ship arrival time is not so big. So queueing time at exclusive terminal does not rise sharply near 80-90 berth occupancy rate.

• Journal of Korea Spatial Information System Society
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• v.9 no.3
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• pp.25-33
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• 2007

The local governments of major cities in Korea are giving focus on public transportation to reduce congestion and improve accessibility in city areas. In this regards, the proper measurement of accessibility is now a key policy requirement for reorganizing the public transport network. Public transport routing problems, however, are considered to be highly complicated since a multi-mode travel generates different combinations of accessibility. While most of the previous research efforts on measuring transport accessibility are found at zone-levels, an alternative approach at a finer scale such as bus links and stops is presented in this study. We proposes a method to compute the optimal route choice of origin-destination pairs and measure the accessibility of the chosen modes combination based on topological configuration. The genetic algorithm is used for the computation of the journey paths, whereas the space syntax theory is used for the accessibility. This study used node-link data in GIS instead of axial lines which are manually drawn in space syntax. The resulting accessibilities of bus stops are calibrated by O-D survey data and the proposed process is tested on a CBD of Seoul.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.3
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• pp.463-469
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• 2010

This research is performed to obtain positive evidences of Mori cortex, a kind of oriental medicinal herbs, in the cellular levels. The extracts of M. cortex have shown anti-inflammatory effects against cutaneous inflammation and clinical effects on pulmonary asthma and congestion in oriental medicine. Thus BV2 cells were chosen because microglia are considered as the main immunocompetent cells in the central nervous system. Lipopolysaccharide (LPS)-induced microglial activation of cultured BV2 cells and subsequent release of nitric oxide (NO) and Prostaglandin E2 (PGE2) were effectively suppressed by methylene chloride extract of Morus alba L. (MEMA). From the inflammation-mediated mRNA and protein analyses, we showed that inducible NO synthase (iNOS), cyclooxygenase-2 (COX-2), interleukin-$1{\beta}$ (IL-$1{\beta}$) and tumor necrosis alpha (TNF-${\alpha}$) induced by LPS were markedly decreased by MEMA treatment. From the observation of nuclear factor-kB (NF-${\kappa}B$) which is controlling and mediating inflammation through COX-2 and iNOS, there showed that p65, a subunit of NF-${\kappa}B$, was increased in nuclear and $I{\kappa}B$, a competitor of NF-${\kappa}B$, was recovered in cytosol after MEMA treatment. These are corresponding with results of iNOS, COX-2, IL-$1{\kappa}$ and TNF-${\alpha}$, and confirm some suppressive effect against transcriptional activation of NF-${\kappa}B$. In conclusion, the anti-inflammatory action of M. cortex against BV2 microglia cells is expected to protect nerve tissues through suppression of neuronal inflammation in various neurodegenerative diseases.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.8 no.1
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• pp.9-21
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• 2002

Object The effect of Banhasasim-tang extracts on the hepatic, splenic toxicity and induced by Doxorubicin administration(Three injection protocol) were monitored using male ICR mice. Method The changes of body weigh, organ weights of liver and spleen were observed with blood GOT and GPT level. Results 1. Increase of absolute and relative liver weight observed in Doxorubicin treatment group were dose-dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of liver congestion and necrotic spot were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group. It is also demonstrated that elevated serum GOT and GPT levels in Doxorubicin treatment group were significantly decreased in Banhasasim-tang extracts dosing groups. 2. Decrease of absolute and relative spleen weight observed in Doxorubicin treatment group were dose dependently inhibited by Banhasasim-tang extracts. In addition, the degrees of splenic atrophy were significantly and dose-dependently decreased after Banhasasim-tang extracts dosing groups compared to that of Doxorubicin treatment group.

• The Korea Journal of Herbology
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• v.25 no.2
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• pp.41-54
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• 2010

Objectives : This study was carried out to investigate the anti-toxicity effect of Hwangryunhaedoktang on the dried Mylabris phalerata extract containing cantharidin in ICR mouse. Methods : Dried Mylabris phalerata extracts were orally administered at dosage level 2000, 1000, 500, 250 and 125mg/kg, respectively with and/or without administration of Hwangryunhaedoktang 200mg/kg. During 2 weeks, the changes of body weight, mortality, $LD_{50}$, macroscopic changes of gastrointestinal tract and liver, changes of serum gastrin and somatostatin levels were observed. Results : Decrease of body weight gains was observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Increase of mortality rates was observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. The $LD_{50}$ of dried Mylabris phalerata extract in male mice significantly increased in a case of concomitant used of Hwangryunhaedoktang 268.86 vs 662.05mg/kg. Clinical signs were observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging after dosaging. Increase of number of hemorrhagic and/or erythematous spots in the gastrointestinal tracts, enlargement and congestion in the liver were observed in dried Mylabris phalerata extract-dosing groups, but it was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Increase of serum gastrin level was observed in dried Mylarbis phalerata extract-dosing groups, these state of abnormal increase was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Decrease of serum somatostatin level was observed in dried Mylabris phalerata extract-dosing groups, these state of abnormal decrease was significantly developed in Hwangryunhaedoktang extract-dosing groups after dosaging. Conclusions : We could conclude that the Hwangryunhaedoktang has anti-toxicity effect on the dried Mylabris phalerata extract containing cantharidin.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.4
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• pp.69-89
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• 2008

Purpose: This study was performed to evaluate anti-oxidant activities and anti-inflammatory effects of Sungyoutanggagambang(SYTG). Methods: In the study of anti-oxidant activities. SYTG was investigated by DPPH radical scavenger activity. superoxide dismutase activity and superoxide anion radical scavenger activity. In the study of anti-inflammatory effects. SYTG was investigated using cultured cells and murine models. As for the parameters of inflammation. levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were measured in mouse lung fibroblast cells(mLFCs) and RAW264.7 cells. Results: Prior to the experiment. we investigated the security of SYTG by measuring GOT and GPT in serum. 1. SYTG showed high antioxidant activity in a concentration-dependent degree by measured scavenging activity of DPPH free radical, superoxide dismutase and superoxide anion radical. 2. SYTG inhibited IL-1$\beta$, IL-6. TNF-$\alpha$, COX-2 and NOS-II mRNA expression as compared with the control group in a concentration-dependent degree in RAW264.7 cell line. 3. SYTG inhibited IL-1$\beta$, IL-6 production significantly at 100 ${\mu}g/ml$ and TNF-$\alpha$ production significantly at 50, 100 ${\mu}g/ml$ as compared with the control group in RA W264.7 cell line. 4. SYTG inhibited IL-1$\beta$, and IL-6 production significantly as compared with the control group in serum of acute inflammation-induced mice. and decreased IL-1$\beta$, IL-6 production in spleen tissue. and also decreased IL-1$\beta$, IL-6 production in liver tissue. Conclusion: These results suggest that SYTG can be useful in treating diverse female diseases caused by inflammation such as endometrosis, myoma, pelvic congestion. chronic cervicitis, chronic pelvic inflammatory disease and so on.

• The Journal of Bigdata
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• v.6 no.1
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• pp.1-12
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• 2021

The rapid growth of mobile-based online shopping and the appearance of untact business initiated by COVID-19 has led to an explosive increase in demand for logistics services such as delivery services. In order to respond to the rapidly growing demand, most logistics and distribution companies are working to improve customer service levels through the establishment of a full-filament center in the city center. However, due to social factors such as high land prices and traffic congestion, it becomes more difficult to establish the logistics facilities in the city center. In this study, it has been proposed the way to choose the candidate locations for the shared distribution centers among the space nearby the tall-gate which can be idle after the smart tolling service is widely extended. In order to evaluate the candidate locations, it has been evaluated the centralities of all candidates using social network analysis (SNA). To understand the result considering the characteristics of centrality, the network structure was regenerated based on the distance and the traveling time, respectively. It is possible to refer the result of evaluation based on the cumulative relative importance to choose the best set of candidates.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.4
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• pp.653-660
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• 2021

Renewable energy resources are rapidly becoming an integral part of electricity generation portfolios around the world due to declining costs, government subsidies, and corporate sustainability goal. Interacting wind, solar, and load forecast errors can create significant unpredictable impacts on the distribution system, feeder congestion, voltage standard and reactive power stability margins. These impacts will be increasing with the increasing penetration levels of variable renewable generation in the power systems. There is a limit to the maximum amount of renewable energy sources that can be connected in a distribution feeder by the connection rule of transmission & distribution facility in Korea. This study represents the decision plans of hosting capacity for distribution feeders without the need for significant upgrades to the existing transmission infrastructure. Especially, the paper suggests and discusses the hosting capacity standard of feeder cables and minimum load calculation of distribution feeders.