• Title/Summary/Keyword: Congenital tremor

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Detection of atypical porcine pestivirus (APPV) from a case of congenital tremor in Korea (포유자돈 선천성 진전증 증례에서 atypical porcine pestivirus (APPV) 검출)

  • Kim, Seung-Chai;Jeong, Chang-Gi;Yoon, Seung-Min;Lee, Ki-Ho;Yang, Myoun-Sik;Kim, Bumseok;Lee, Seung-Yoon;Kang, Seog-Jin;Kim, Won-Il
    • Korean Journal of Veterinary Service
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    • v.40 no.3
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    • pp.209-213
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    • 2017
  • Congenital tremor (CT) is a sporadic neurodegenerative disease reported in suckling piglets worldwide. Since atypical porcine pestivirus (APPV) was first identified in US in 2015, it has also subsequently detected in Europe and China as a causative pathogen for CT in suckling piglets. Three new-born piglets died from severe tremor was submitted to Chonbuk National University-Veterinary Diagnostic Center (CBNU-VDC) and various tissues (lung, lymph node, brain, intestine) were tested with panpestivirus RT-PCR and APPV NS5B-specific RT-PCR. All of the samples were positive by both of the PCR tests and the partial NS5B sequences of APPV were confirmed by sequencing on the PCR products of APPV NS5B-specific RT-PCR. Therefore, we report the first identification of APPV from a case of CT in suckling piglets in Korea.

Successful Management of Post-Attenuation Neurologic Signs and Portal Hypertension in a Dog with Congenital Portoazygos Shunt

  • Jin-Young Kim;Kun-Ho Song;Joong-Hyun Song
    • Journal of Veterinary Clinics
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    • v.41 no.2
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    • pp.95-100
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    • 2024
  • A 6-year-old neutered male Poodle with a body weight of 2.7 kg was diagnosed with a congenital extrahepatic portoazygos shunt presented with progressive hepatic encephalopathy. Five days after surgical attenuation, the patient showed post-attenuation neurological signs (PANS) such as generalized tonic-clonic seizure, dull mentation, and tremor. PANS were successfully managed with antiepileptic drugs, but third-space fluid accumulation (ascites and peripheral edema) and phlebectasia were newly identified, suggesting marked portal hypertension (PHT). Telmisartan, spironolactone, carvedilol, and prednisolone were sequentially administered. Three months after surgery, both abnormal clinicopathological values such as anemia and hypoalbuminemia, and clinical signs completely resolved. Herein, we report successful management strategies for PANS and PHT in a dog following surgical attenuation of a congenital portoazygos shunt.

Congenital Cleft of Anterior Arch and Partial Aplasia of the Posterior Arch of the C1

  • Choi, Ji-Won;Jeong, Je-Hoon;Moon, Seung-Myung;Hwang, Hyung-Sik
    • Journal of Korean Neurosurgical Society
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    • v.49 no.3
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    • pp.178-181
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    • 2011
  • Congenital anomalies in arches of the atlas are rare, and are usually discovered incidentally. However, a very rare subgroup of patients with unique radiographic features is predisposed to transient quadriparesis after minor cervical or head trauma, A 46-year-old male presented with a 2-month history of tremor and hyperesthesia of the lower extremities after experiencing a minor head trauma. He said that he had been quadriplegic for about 2 weeks after that trauma. Radiographs of his cervical spine revealed bilateral bony defects of the lateral aspects of the posterior arch of C1 and a midline cleft within the anterior arch of the atlas. A magnetic resonance imaging revealed an increased cord signal at the C2 level on the T2-weighted sagittal image. A posterior, suboccipital midline approach for excision of the remnant posterior tubercle was performed. The patient showed significant improvement of his motor and sensory functions. Since major neurologic deficits can be produced by a minor trauma, it is crucial to recognize this anomaly.