• Title/Summary/Keyword: Confidence Value

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Antimicrobial Activity and Acute Toxicity of Natural Rutin (천연 Rutin의 항균효과와 급성독성에 미치는 영향)

  • Rym, Kyo-Hwan;Eo, Seong-Kug;Kim, Young-So;Lee, Chong-Kil;Han, Seong-Sun
    • Korean Journal of Pharmacognosy
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    • v.27 no.4
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    • pp.309-315
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    • 1996
  • As part of our search for less toxic antimicrobial agents from natural resources, antimicrobial activity of rutin isolated from Sophora japonica was tested in vitro against four kinds of gram positive bacteria and four kinds of gram negative bacteria by serial broth dilution method. Among eight kinds of bacteria tested, the antimicrobial activity of rutin was the most potent against Mycobacterium smegmatis showing MIC of $375\;{\mu}g/ml$. The acute toxicity of rutin was examined in mice and rats. and $LD_{50}$ value administered intraperitoneally in mice was 650 mg/kg(Confidence limit: 894-1,473 mg/kg). There were no significant changes in serum biochemical values and histopathological changes as compared with those of control after intraperitoneal administration with rutin in rats.

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Studies on the Comparison of Physicochemical Properties and the Presumption of Sensory Quality of Japonica Rice Varieties Cultivated in Korea and Japan (한국과 일본의 자포니카종 쌀에 대한 이화학적 특성의 비교 및 관능품질의 추정에 관한 연구)

  • 홍원표;이성갑;박승남
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.596-604
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    • 2001
  • Twelve varieties of Korean rice and ten varieties of Japanese rice were selected. After being milled. they were analyzed about various physicochemical properties such as moisture, protein and amylose, a -amylase activity, gelatinization properties. And after being cooked with proper amount of water texture and other physical properties were measured by Texturometer, Tensipresser and Rheolograph-micro. Finally the sensory evaluation test was carried out. The results were as follows. 1. In case of protein contents, amylose contents and $\alpha$-amylase activity, Korean rice had a slightly higher value than Japanese As a consequence. Korean rice showed a little stronger hardness and a little weaker stickiness compared with Japanese rice. 2. Amylose contents showed very high correlation with other physicochemical properties and peak viscosity and gelatinization temperature of RVA, the ratio of stickiness to hardness( -Hl/Hl ) of Texturometer and the tan $\delta$(the ratio of dynamic loss to dynamic viscoelasticity) of Rheolograph-micro showed high correlation with other analyzed properties. 3. The ( -/+)work balance of low compression test(25% ) of Tensipresser analysis(texture analysis on the surface of cooked rice) and tan f of Rheolograph-micro showed very high correlation with sensory evaluation results. By using this parameters as major independent variables, some trials to derive high confidence multiple regression equations were accomplished. By the equations it would be possible to make an approximate pre-estimate of eating quality for unknown japonica rice.

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A Comparative Study on Bearing Capacity of Single Pile Based on Calculation Method (산정방법에 따른 단말뚝의 지지력 비교연구)

  • 이영대;심재현
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.39 no.2
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    • pp.124-133
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    • 1997
  • Pile load test is good for estimating pile bearing capacity, but using this method is limited by time and cost required. Dynamic and static method is more convenient and economical, but confidence of estimated value by dynamic and static method are lower than that of pile load test. After being compared pile bearing capacity data obtained from pile load test with those of other two methods, the results from this study were summarised as follows. For allowable bearing capacity values greater than 175t per pile, bearing capacity acquired from static method was higher than that acquired from pile load test, whereas bearing capacity acquired from pile load test was higher than that acquired from static method for values under 175 per pile. It was that variance of bearing capacity was large when bearing capacity obtained by dynamic method was higher than 250t. Also bearing capacity based on dynamic method was higher than that based on pile load test. Allowable bearing capacity get from dynamic method suggested that carefull precautions are necessary in application for allowable bearing capacity values higher than 2S0ton per pile.

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Geometrically Inhomogeneous Random Configuration Effects of Pt/C Catalysts on Catalyst Utilization in PEM Fuel Cells (연료전지 촉매층 내 촉매활성도에 대한 탄소지지 백금 촉매의 기하학적 비등방성 효과에 관한 연구)

  • Shin, Seungho;Kim, Ah-Reum;Jung, Hye-Mi;Um, Sukkee
    • Journal of the Korean Society for Precision Engineering
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    • v.31 no.10
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    • pp.955-965
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    • 2014
  • Transport phenomena of reactant and product are directly linked to intrinsic inhomogeneous random configurations of catalyst layer (CL) that consist of ionomer, carbon-supported catalyst (Pt/C), and pores. Hence, electrochemically active surface area (ECSA) of Pt/C is dominated by geometrical morphology of mass transport path. Undoubtedly these ECSAs are key factor of total fuel cell efficiency. In this study, non-deterministic micro-scale CLs were randomly generated by Monte Carlo method and implemented with the percolation process. To ensure valid inference about Pt/C catalyst utilization, 600 samples were chosen as the number of necessary samples with 95% confidence level. Statistic results of 600 samples generated under particular condition (20vol% Pt/C, 30vol% ionomer, 50vol% pore, and 20nm particle diameter) reveal only 18.2%~81.0% of Pt/C can construct ECSAs with mean value of 53.8%. This study indicates that the catalyst utilization in fuel cell CLs cannot be identical notwithstanding the same design condition.

Random Parameter Negative Binomial Models of Interstate Accident Frequencies on Interchange Segment by Interchange Type/Region (RPNB 모형을 이용한 고속도로 인터체인지 구간에서의 교통사고모형 - 인터체인지 형태별/지역별로)

  • Lee, Geun Hee;Park, Minho;Roh, Jeonghyun
    • International Journal of Highway Engineering
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    • v.16 no.5
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    • pp.133-142
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    • 2014
  • PURPOSES : The objective was to develop the advanced method which could not explain each observation's specific characteristic in the present negative binomial method that results in under-estimation of the standard error(t-value inflation) and affects the confidence of whole derived results. METHODS : This study dealt with traffic accidents occurring within interchange segment on highway main line with RPNB(Random Parameter Negative Binomial) method that enables to take account of heterogeneity. RESULTS : As a result, AADT and lighting installation type on the road were revealed to have random parameter and in terms of other geometric variables, all were derived as fixed parameter(same effect on every segment). Also, marginal effects were adapted to analyze the relative effects on traffic accidents. CONCLUSIONS : This study proves that RPNB method which considers each observation's specific characteristics is better fitted to the accident data with geometrics. Thus, it is recommended that RPNB model or other methods which could consider the heterogeneity needs to be adapted in accident analysis.

A Study of Determination of Minimum Detectable Activity at Measuring of Pu Isotopes in Environmental Samples (환경시료 중 Pu 측정에서 최소검출방사능 농도 산출에 대한 연구)

  • Lee, Myung-Ho;Cho, Young-Hyun;Choi, Gun-Sik;Lee, Chang-Woo;Shin, Hyun-Sang
    • Analytical Science and Technology
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    • v.14 no.1
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    • pp.64-71
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    • 2001
  • In this paper, the formula of lower limit of detection considering the measuring time of sample and background was derived using the basic concepts of lower limit of detection. Among parameters affecting the determination of MDA value, the MDA values were calculated with variation of amount of sample and measuring time of sample and background. The results of adequate division between the measuring time of sample and that of background studied in this research make it possible to evaluate confidence limits on the radio analytical results in the environmental sample.

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Electronic Cash for Central Bank′s Monetary Policy

  • Lim, Kwang-Sun;Park, Jung-Su;Hyun, Tchang-Hee
    • Journal of Korea Technology Innovation Society
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    • v.1 no.1
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    • pp.96-105
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    • 1998
  • Electronic cash affects central bank in many areas, in particular regarding the issuance of money, supervision of cashless payments, supervision of the banking system and monetary policy. The effects of electronic cash on central bank policies, the security and integrity of the payment system, and naturally also on single sector such as company engaged in the transport of money and valuables, depend mainly on the extent to which the new payment methods can replace cash. The possible development of electronic cash merits special attention from central banks for at least three reasons. First, central banks are concerned that the introduction of the new payment instrument should have no adverse effect on public confidence in the payment system and payment media. Second, although the substitution of electronic cash for other forms of money should not theoretically hamper central bank's ability to control the money supply, it might, however, have practial implications, at least in the long run, which need to be carefully examined. Third, because electronic cash may be used for payments of very small value, they have the potential, more than any other cashless instrument, to take over the role of notes and coins in the economy and, therefore, have implications for central bank's activities and revenues.

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An extremum method for bending-wrinkling predictions of inflated conical cantilever beam

  • Wang, Changguo;Du, Zhenyong;Tan, Huifeng
    • Structural Engineering and Mechanics
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    • v.46 no.1
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    • pp.39-51
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    • 2013
  • An extremum method is presented to predict the wrinkling characteristics of the inflated cone in bending. The wrinkling factor is firstly defined so as to obtain the wrinkling condition. The initial wrinkling location is then determined by searching the maximum of the wrinkling factor. The critical wrinkling load is finally obtained by determining the ratio of the wrinkling moment versus the initial wrinkling location. The extremum method is proposed based on the assumption of membrane material of beam wall, and it is extended to consider beam wall with thin-shell material in the end. The nondimensional analyses show that the initial wrinkling location is closely related to the taper ratio. When the taper ratio is higher than the critical value, the initial wrinkles will be initiated at a different location. The nondimensional critical wrinkling load nonlinearly increases as the taper ratio increases firstly, and then linearly increases after the critical taper ratio. The critical taper ratio reflects the highest load-carrying efficiency of the inflated cone in bending, and it can be regarded as a measure to optimize the geometry of the inflated cone. The comparative analysis shows fairly good agreement between analytical and numerical results. Over the whole range of the comparison, the mean differences are lower than 3%. This gives confidence to use extremum method for bending-wrinkling analysis of inflated conical cantilever beam.

Are theoretically calculated periods of vibration for skeletal structures error-free?

  • Mehanny, Sameh S.F.
    • Earthquakes and Structures
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    • v.3 no.1
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    • pp.17-35
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    • 2012
  • Simplified equations for fundamental period of vibration of skeletal structures provided by most seismic design provisions suffer from the absence of any associated confidence levels and of any reference to their empirical basis. Therefore, such equations may typically give a sector of designers the false impression of yielding a fairly accurate value of the period of vibration. This paper, although not addressing simplified codes equations, introduces a set of mathematical equations utilizing the theory of error propagation and First-Order Second-Moment (FOSM) techniques to determine bounds on the relative error in theoretically calculated fundamental period of vibration of skeletal structures. In a complementary step, and for verification purposes, Monte Carlo simulation technique has been also applied. The latter, despite involving larger computational effort, is expected to provide more precise estimates than FOSM methods. Studies of parametric uncertainties applied to reinforced concrete frame bents - potentially idealized as SDOF systems - are conducted demonstrating the effect of randomness and uncertainty of various relevant properties, shaping both mass and stiffness, on the variance (i.e. relative error) in the estimated period of vibration. Correlation between mass and stiffness parameters - regarded as random variables - is also thoroughly discussed. According to achieved results, a relative error in the period of vibration in the order of 19% for new designs/constructions and of about 25% for existing structures for assessment purposes - and even climbing up to about 36% in some special applications and/or circumstances - is acknowledged when adopting estimates gathered from the literature for relative errors in the relevant random input variables.

Null Glutathione S-transferase T1 and M1 Genotypes and Oral Cancer Susceptibility in China and India - a Meta-analysis

  • Peng, Jie;Liu, Hong-Zhou;Zhu, You-Jia
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.287-290
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    • 2014
  • Objective: Genetic variation is considered to strongly impact on detoxification of carcinogens and therefore is related to cancer risk. However, findings for the null genotypes of GSTT1 and GSTM1 have not always been consistent. Therefore the present meta-analysis was conducted. Methods: We accessed the reported study at different research areas and used various databases, including PubMed and Wanfang Med Onlion from 1990 to May 1st 2013. We calculated the odds ratio (OR), 95% confidence interval (CI) and P value for oral cancer by using Review Manager 5.1 and STATE 12. Results: We found that there was no increased oral cancer risk among subjects carrying GSTM1 and GSTT1 null genotype (OR=1.35, 95%CI=0.68-2.68, P=0.39) and (OR=1.41, 95%CI=0.72-2.77, P=0.31) in the Chinese population. In contrast, in studies in India a significant correlation between GSTM1 null genotype and oral cancer was observed (OR=1.59, 95%CI=1.20-2.11, P=0.001), but not in GSTT1 (OR=1.21, 95% CI=0.84-1.74, P=0.31). Conclusion: We discovered that GSTM1 deletion polymorphism had a significant effect on the susceptibility of oral cancer in the Indian population.