• Title/Summary/Keyword: Concurrent Approach

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Case Report on Complete Response and 5 year Survival of Non-Small Cell Lung Cancer IIIB Patient Treated with Integrative Medicine (한양방통합치료로 완치되어 5년 생존에 도달한 3기B 비소세포성폐암 증례 보고)

  • Bang, Sunhwi;Yun, Youngju;Choi, Junyong;Han, Changwoo;Kim, Soyeon;Park, Seongha;Hong, Jinwoo;Kwon, Jungnam;Lee, In
    • The Journal of Korean Medicine
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    • v.42 no.1
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    • pp.119-128
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    • 2021
  • Objectives: This is a five-year survival case report on non-small cell lung cancer (NSCLC) treated with western medicine and traditional Korean medicine. 44-year old man diagnosed NSCLC IIIB in 2015 went through two months' concurrent chemoradiotherapy (CCRT) first, however the cancer did not response. After CCRT he began to take intensive integrative therapy including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, herbal medicinal product of ginseng, hyperthermia, Thymosin α1, and mega vitamin C injection for 4 years and 9 months. After three months of intensive treatment, the state of cancer changed first to partial response and then complete response. He finally succeeded in five-year survival without any recurrence or complication in 2020, We suggest that integrative approach including traditional Korean medicine can be a meaningful treatment option for nonoperable NSCLC. Further studies with more cases should be performed to establish proper treatment protocol of integrative medicine for lung cancer.

A Development of Feature-based Wire Harness Drawing System (특징형상 기반 자동차 전장도면설계 시스템 개발 연구)

  • 이상준;이수홍
    • Korean Journal of Computational Design and Engineering
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    • v.1 no.3
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    • pp.177-188
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    • 1996
  • An approach to providing computational support with an expert shell is discussed with the scope of an industrial wire harness design, especially at a manufacturing stage. Key issues include the development of an architecture that supports a frequent design change among engineers associated with different parts of the wiring design process and the development of hierarchical representations that capture the different characteristics (e.g., connectivity, configuration) of the harnesses. The abstraction of design information results in features, while the abstraction of drawing elements leads to the definition of objects. These abstractions are essential for efficient transactions among people and computer tools in a domain that involves numerous interacting constraints. In this paper the strategy for the problem decomposition, the definition of features, and the ways in which features are shared by various operations and design changes, are discussed. We conclude with a discussion of some of the issues raised by the project and the steps underway to address them.

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How to approach feeding difficulties in young children

  • Yang, Hye Ran
    • Clinical and Experimental Pediatrics
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    • v.60 no.12
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    • pp.379-384
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    • 2017
  • Feeding is an interaction between a child and caregiver, and feeding difficulty is an umbrella term encompassing all feeding problems, regardless of etiology, severity, or consequences, while feeding disorder refers to an inability or refusal to eat sufficient quantities or variety of food to maintain adequate nutritional status, leading to substantial consequences, including malnutrition, impaired growth, and possible neurocognitive dysfunction. There are 6 representative feeding disorder subtypes in young children: infantile anorexia, sensory food aversion, reciprocity, posttraumatic type, state regulation, and feeding disorders associated with concurrent medical conditions. Most feeding difficulties are nonorganic and without any underlying medical condition, but organic causes should also be excluded from the beginning, through thorough history taking and physical examination, based on red-flag symptoms and signs. Age-appropriate feeding principles may support effective treatment of feeding difficulties in practice, and systematic approaches for feeding difficulties in young children, based on each subtype, may be beneficial.

Sedation in the Critically Ill Patients (중환자에서의 진정 진통 치료)

  • Kim, Tae-Hyung
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.2
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    • pp.117-123
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    • 2012
  • Optimal level of sedation and analgesia is important for the comfort and safety of critically ill patients. However, suboptimal sedation is relatively common in the intensive care unit (ICU) and it could cause prolonged mechanical ventilation and ICU stay, also increase delirium and ICU acquired weakness and resultant decreased survival. Therefore, accurate assessment of the level of sedation and analgesia, maintaining adequate level of sedation, and daily evaluation of each patient and following adjustment could be important treatment strategy in critically ill patients. Recently, the strategy for sedation in the ICU is changing toward the direction of lowering sedation level or even "no sedation" with concurrent use of analgesics and the use of ultra short acting analgesics could be helpful in some patients. Clinicians should be aware of the importance of algorithmic approach including daily interruption of sedative and assessment of sedation level and especially in the patients under mechanical ventilation, organizational approaches such as the 'ABCDE' bundle could improve the management of critically ill patients.

Giant Intrathoracic Meningocele and Breast Cancer in a Neurofibromatosis Type I Patient

  • Malla, Hridayesh Pratap;Park, Bong Jin;Koh, Jun Seok;Jo, Dae Jean
    • Journal of Korean Neurosurgical Society
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    • v.59 no.6
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    • pp.650-654
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    • 2016
  • Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of chromosome 17, one would expect concurrence of neurofibromatosis and breast cancer. However, incidence of such co-disorders is very rare in the literature. Here, the authors report a case of a 50-year-old female patient with NF-1 and concurrent cancer of the left breast, who had a huge bilobulated intrathoracic meningocele with thoracic dystrophic scoliosis, treated surgically via a posterior-only approach for the meningocele and spinal deformity in the same setting.

A Heuristic Approach Solving for the Complex Design with Precedence Constraints in Concurrent Engineering (복합설계를 위한 동시공학적 접근방법)

  • Cho, Moon-Soo;Kim, Chang-Yeong
    • Journal of Korean Institute of Industrial Engineers
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    • v.24 no.2
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    • pp.185-197
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    • 1998
  • Engineering design involves the specification of many variables that define a product, how it is made, and how it behaves. Before some variables can be determined, other variables must first be known or assumed. This fact implies a precedence order of the variables, and of the tasks of determining these variable consequently. Moreover, design of complex systems may involve a large number of design activities. In this paper, the activity-activity incidence matrix is considered as a representation of design activity analysis which mainly focuses on the precedence constraint. In order to analyze the activity-activity incidence matrix, a heuristic algorithm is proposed, which transforms an activity-activity, parameter-formula, and parameter-parameter incidence matrix into a lower triangular form. The analysis of the structured matrices can not only significantly reduce the overall project complexity by reorganizing few critical tasks in practice, but also aims at obtaining shorter times considering the solution structure by exploring concurrency.

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A Study on CAE for the Design of the Seat Frame of Fiber-reinforced Composite Material (첨단섬유강화 복합재료 시트프레임 설계를 위한 CAE 연구)

  • 허용정;이순홍;최금호
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1995.10a
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    • pp.933-937
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    • 1995
  • The design of injection molded prlymeric parts has been done empirically, since it requires profound knowledge about the moldability and causal effects on the properties of the parts. This study shows CAE approach for the design of the seat frame of fiber-reinforced composite material in order to realize the concept os rationsl design for the productivity and quality of mold making. The knowledge-based CAE system is constructed by adding the knowledge-basw module for the design evaluation and appropriate CAE programs for mold design analysis in order to provied designers, at the initial design stage, with comprehensive process knowledge for the performance analysis and the design evaluation. A knowledge-based CAE system is a new tool which enables the concurrent design with integrated and balanced design decisions at the initial design stage of injection molding.

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Optimizing Caching in a Patch Streaming Multimedia-on-Demand System

  • Bulti, Dinkisa Aga;Raimond, Kumudha
    • Journal of Computing Science and Engineering
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    • v.9 no.3
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    • pp.134-141
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    • 2015
  • In on-demand multimedia streaming systems, streaming techniques are usually combined with proxy caching to obtain better performance. The patch streaming technique has no start-up latency inherent to it, but requires extra bandwidth to deliver the media data in patch streams. This paper proposes a proxy caching technique which aims at reducing the bandwidth cost of the patch streaming technique. The proposed approach determines media prefixes with high patching cost and caches the appropriate media prefix at the proxy/local server. Herein the scheme is evaluated using a synthetically generated media access workload and its performance is compared with that of the popularity and prefix-aware interval caching scheme (the prefix part) and with that of patch streaming with no caching. The bandwidth saving, hit ratio and concurrent number of clients are used to compare the performance, and the proposed scheme is found to perform better for different caching capacities of the proxy server.

Scheduling Design and Simulation of Software Components for EPS System based on AUTOSAR (AUTOSAR기반 EPS 시스템 소프트웨어 컴포넌트의 스케줄링 설계 및 시뮬레이션)

  • Park, Gwang-Min;Kum, Dae-Hyun;Son, Byeong-Jeom;Lee, Seong-Hun
    • Journal of Institute of Control, Robotics and Systems
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    • v.16 no.6
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    • pp.539-545
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    • 2010
  • Through the AUTOSAR methodology, the embedded software shall become more flexible, reusable, maintainable than ever. However, it is not mentioned about specific timing constraints of software components in AUTOSAR. There are a few basic principles for mapping runnable entities. At this point, AUTOSAR software design with optimal scheduling method is one of the enabling technologies in vehicle embedded system. This paper presents an approach based on mapping runnable entities and task scheduling design method for EPS (Electric Power Steering) software components, based on AUTOSAR. In addition, the experimental results of concurrent simulation show that the proposed scheduling technique and timing synchronization in the software component design can achieve the improved torque ripple performance and it well suited for EPS application software.

A Semantic Network Approach to PPO (Products, Processes, Organizations/Resources) Modeling for PDM Systems

  • Hyo-Won Suh;Heejung Lee;Seungchul Ha
    • Korean Journal of Computational Design and Engineering
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    • v.4 no.3
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    • pp.238-246
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    • 1999
  • The modeling method to support product development processes (PDP) must have certain characteristics including the ability to represent multiple viewpoints of the product development and integrate with currently available analysis and design methods based on CE concept. This paper describes the reference model to support multiple viewpoints (PPO: Products, Processes, and Organizations/Resources viewpoints) of the product development processes, from which each model (Products model, Processes model, and Organizations/Resources model) can be extracted, as well as produces PPO data schema. This reference model has associative relationships among the products, processes, and organizations/resources. To allow the extensibility to support design evolution, we propose structured dat representation methods using semantic network, which can be constructed through first-order logic. The product development processes is so represented by specifying entities and semantic relationships among them hat he appropriate information can be accessed and all of the relevant attributes about the entities can be retrieved simultaneously.

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