• 동의생리병리학회지
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• 제20권6호
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• pp.1728-1731
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• 2006

To develop the Korean Standard Differentiation of the Symptoms and sings, We investigate concordance rate of symptoms between Korean Medicine Doctors. Two Korean medicine doctor surveyed symptoms with the Korean Standard Differentiation of the symptoms and sings for the Stroke(KSDS) case report form in stroke patients within 1 month of onset. The concordance rate of inspection, auscultation and olfaction, inquiry, and pulse feeling and palpitation are respectively 0.79, 0.90, 0.91,0.80. The study of inspection, pulse feeling and palpitation will be continued to evaluate concordance rate.

• 응용통계연구
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• 제28권6호
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• pp.1289-1312
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• 2015

본 연구에서는 상장 기업을 중심으로 산업 부도의 동조화 현상에 대해 살펴보았다. 순위상관계수인 스피어만의 로(${\rho}$)와 켄달의 타우(${\tau}$)를 이용하여 부도의 컨코던스 즉, 부도율의 움직임이 얼마나 일치하는지를 측정하였다. 여기서 스피어만의 로와 켄달의 타우는 분포 가정이 필요하지 않고, 자료 숫자가 적거나 극단값을 갖는 경우에도 분석이용이하다는 장점을 가진 비모수 통계적 방법이다. 본 연구의 목적은 산업 부도의 동조화 현상을 살펴봄으로써 향후 일어날 금융위기를 예측하는 데에 있다. 또한 기업 경영인을 비롯하여 모든 시장참여자의 투자결정 및 위험관리, 더 나아가 산업 전반에 대한 이해에 도움이 되길 바란다.

• 기술혁신연구
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• 제18권2호
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• pp.121-145
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• 2010

미국특허를 대상으로 국가 27대 녹색기술의 기술산업연계구조 분석을 수행하였고, 이를 통해서 산업 녹색도 지수를 개발하였다. 산업의 녹색도 지수는 녹색기술 창출지수 및 활용지수의 합으로 규정하였으며, 산업의 녹색기술 수용도의 의미를 갖는다. 지수 분석결과, 전체특허기술에 대한 수용도가 매우 높았던 대부분의 IT 관련 산업들은 27대 녹색기술에 대한 수용도 즉, 산업 녹색도는 상대적으로 낮게 나타나는 경향을 나타내었다. 반면, 배터리, 무기화합물 등 화학 관련 산업 및 에너지 관련 산업의 경우 산업의 녹색도가 전체특허 기술 수용도 대비 월등히 증가하여, 녹색성장시대에 크게 주목받는 산업으로 나타났다. 녹색 기술에 대한 효과적인 투자전략 수립을 위해서는, 관련 산업으로의 파급효과를 측정하는 것이 매우 중요하며, 본 연구에서 제시한 산업녹색도 지수는 이에 대한 정량적이면서 활용이 용이한 대안으로 제시된다. 한편, 본 연구결과로 제시된 산업의 기술 수용지수는 녹색기술 분야에 한정되지 않고 타 기술분야를 대상으로도 범용적으로 활용할 수 있다.

• Journal of Veterinary Science
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• 제22권1호
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• pp.14.1-14.11
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• 2021

Background: Quantitation of urine protein is important in dogs with chronic kidney disease. Various analyzers are used to measure urine protein-to-creatinine ratios (UPCR). Objectives: This study aimed to compare the UPCR obtained by three types of analyzers (automated wet chemistry analyzer, in-house dry chemistry analyzer, and dipstick reading device) and investigate whether the differences could affect clinical decision process. Methods: Urine samples were collected from 115 dogs. UPCR values were obtained using three analyzers. Bland-Altman and Passing Bablok tests were used to analyze agreement between the UPCR values. Urine samples were classified as normal or proteinuria based on the UPCR values obtained by each analyzer and concordance in the classification evaluated with Cohen's kappa coefficient. Results: Passing and Bablok regression showed that there were proportional as well as constant difference between UPCR values obtained by a dipstick reading device and those obtained by the other analyzers. The concordance in the classification of proteinuria was very high (κ = 0.82) between the automated wet chemistry analyzer and in-house dry chemistry analyzer, while the dipstick reading device showed moderate concordance with the automated wet chemistry analyzer (κ = 0.52) and in-house dry chemistry analyzer (κ = 0.53). Conclusions: Although the urine dipstick test is simple and a widely used point-of-care test, our results indicate that UPCR values obtained by the dipstick test are not appropriate for clinical use. Inter-instrumental variability may affect clinical decision process based on UPCR values and should be emphasized in veterinary practice.

• 응용통계연구
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• 제22권3호
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• pp.585-594
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• 2009

마이크로어레이 실험의 실험자들은 원 측정치인 영상을 조사하여 통계적 분석이 가능한 자료의 형태로 변환하는데 이러한 과정을 흔히 사전 처리라고 부른다. 마이크로어레이의 사전 처리는 불량 영상의 제거(filtering), 결측치의 대치와 표준화로 세분되어질 수 있다. 표준화 방법과 결측치 대치 방법 각각에 대하여서는 많은 연구가 보고되었으나, 사전 처리를 구성하는 원소들간의 적정한 순서에 대하여서는 연구가 미흡하다. 표준화 방법과 결측치 대치 방법 중 어느 것이 먼저 실시되어야 하는지에 대하여서 아직 알려진 바가 없다. 본 연구는 사전 처리 순서에 대한 탐색적 시도로서 대장암과 위암을 대상으로 실시한 두 조의 cDNA 마이크로어레이 실험 자료를 이용하여 사전 처리를 구성하는 원소들간의 다양한 순서에 따라 검색된 특이 발현 유전자 군이 어떻게 변화하는지를 분석하고 있다. 즉, 결측치대치와 표준화의 여러가지 방법들의 조합에 따라 검색된 특이 발현 유전자 군이 얼마나 일치적인가를 확인하고자 한다. 결측치 대치 방법으로는 K 최근접 이웃 방법과 베이지안 주성분 분석을 고려하였고, 표준화 방법으로는 전체 표준화, 블럭별 국소(within-print tip group) 평활 표준화 그리고 분산 안정화를 유도하는 표준화 방법을 적용하였다. 따라서 사전 처리를 구성하는 두개 원소가 각각 2개 수준과 3개 수준을 가지고 있고, 두개 원소의 순열에 따른 모든 가능한 사전 처리 개수 수는 12개가 된다. 본 연구에서는 12개 사전 처리 방법 각각에 따라 정상 조직과 암 조직간 특이적으로 발현하는 유전자 군을 검색하였고, 사전 처리 순서를 바꾸었을때 유전자 군이 얼마나 일치적으로 유지되는지를 파악하고 있다. 표준화 방법으로 분산 안정화 표준화를 사용할 경우는 사전 처리 순서에 따라 특이 발현 유전자 군이 다소 민감하게 변하는 것을 보이고 있다.

• 동의신경정신과학회지
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• 제31권1호
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• pp.1-12
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• 2020

Objectives: The purpose of this study was to evaluate the reliability and validity of the instrument on pattern identification for insomnia (PIT-Insomnia) and verify the correlation between PIT-Insomnia and psychological tests. Methods: Two evaluators examined the pattern identification of the participants who met insomnia disorder diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition (DSM-5) and took the Insomnia Severity Index (ISI) score over 15 once manually and twice using the PIT-Insomnia to measure the inter-rater and test-retest reliability. We also conducted the following surveys: the Pittsburgh Sleep Quality Index (PSQI), the Korean version of Beck's depression inventory (K-BDI), the Korean version of the State-Trait Anxiety Inventory (STAI-K), the Korean Symptom checklist-95 (KSCL-95), and the EuroQol-5 dimension (EQ-5D), to measure concurrent validity and correlation between the PTI-Insomnia and psychological tests. Results: 1. The test-retest reliability analysis of the pattern identification results showed moderate agreement, and test-retest reliability analysis of each pattern identification score showed agreements from poor to moderate. 2. The inter-rater reliability analysis of the pattern identification results via manual showed slight agreement, when analysis was performed with calibration, the inter-rater reliability analysis of the pattern identification results via manual showed fair agreement. 3. The concordance analysis between results via manual and the PIT-Insomnia showed poor agreement, when the analysis was performed with calibration, concordance analysis showed fair agreement. 4. The concordance analysis between the PIT-Insomnia and the PSQI showed positive linear correlation. 5. The concordance analysis between the PIT-Insomnia and the PSQI, K-BDI, STAI-K, KSCL-95, and EQ-5D showed that non-interaction between the heart and kidney have positive linear correlation with the K-BDI, anxiety item of KSCL-95, dual deficiency of the heart-spleen have positive linear correlation with somatization item of KSCL-95, paranoia item of KSCL-95, heart deficiency with timidity have positive linear correlation with stress vulnerability item of KSCL-95, parania item of KSCL-95, phlegm-fire harassing the heart have positive linear correlation with K-BDI, paranoia item of KSCL-95, depressed liver qi transforming into fire have positive linear correlation with the anxiety item of KSCL-95, parania item of KSCL-95, all pattern identification have negative linear correlation with EQ-5D. Conclusions: The PIT-Insomnia has moderate agreement of reliability and reflects the severity of insomnia since it has some concurrent validity with the PSQI. There are some correlations between the PTI-Insomnia with specific psychological tests, so we could suggest it can be used appropriately in the clinical situation.

• Asian-Australasian Journal of Animal Sciences
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• 제25권5호
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• pp.733-737
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• 2012

Determination of sex origin of cattle meat by fast and reliable molecular methods is an important measure to ensure correct allocation of export refunds particularly in European countries and also female cattle (cow) slaughter is legally banned in India because of religious beliefs. Based on the DEAD box protein gene located on the X and Y chromosomes, 2 pair of primers were designed and the system of PCR was optimized. Upon PCR amplification, male tissue showed 2 bands, while female tissue resulted in only one band. The accuracy and specificity of the primers was assessed using DNA template extracted from cattle meat of known sex. The protocol was subjected to a blind test and showed 100% concordance, proving its accuracy and reliability.

• 대한간호학회지
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• 제18권3호
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• pp.239-244
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• 1988

The purpose of this study was to identify the accuracy rates(hit ratio) which mean the degree of concordance between pain rating scale differences over time & subjective comparisons. Subjective comparisons mean the responses to the question “how does the pain you are now experiencing compare with the one at the time of the assessment yesterday\ulcorner” Answers to this question were translated into ‘greater’, ‘same’, or ‘less’. KPRS(Korean Pain Rating Scale) was developed through 4 consecutive studies to assess pain extensively & accurately by Lee etc. VAS(Visual Analogue Scale) was reported as valid & veliable measure for the intensity of pain by many researchers. Thirty hospitalized patients with complaints of Headache were partispated in this study during the period from May 1 to July 31, 1987. In conclusion, the accuracy rates of KPRS and VAS were 60%, 67%, respectively.

• 한국산업보건학회지
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• 제23권2호
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• pp.156-163
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• 2013

Objectives: Numerous poisonous substances are used in paint manufacture, but there are differences in the results of GHS classification between the Ministry of Labor(MOL) and the Ministry of Environment(MOE). Therefore, paint manufacturers suffer confusion as to how to classify a given chemical's risk and hazard level. This paper was designed to compare the classification results of chemicals by the MOL and the MOE and suggest a harmonization measure. Methods: After selecting 25 poisonous substances from among the organic solvents, pigments, and additives used in paint manufacturer, the GHS classification results by MOL and MOE were compared. Further the logic and classification of the GHS proposed by each Ministry was analyzed. Based on the derived results, a harmonization plan was proposed. Results: Based on the GHS classification of the poisonous substances, the concordance is 10.0-66.6 %, excluded flammable liquid. The GHS classifications differed based on the suggested building blocks, the sub-classification method used, the references(data sources), and subjective judgment of the experts from each Ministry. In order to pursue the harmonization plan, cooperation is demanded from the MOL and MOE.

• Journal of Preventive Medicine and Public Health
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• 제18권1호
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• pp.51-57
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• 1985

To attempt to measure the effect of domestic product P.H.A. kit 'Hepa-S' after completion of 'Hepa-Vax' vaccination schedule, P.H.A. test and R.I.A. test on the 330 healthy adults were carried out. The results obtained were as follow ; 1. The positive anti HBs rate after completion of 'Hepa-Vax' vaccination were; in P.H.A. test with domestic product P.H.A. kit 81.2%, in P.H.A. test with foreign product P.H.A. kit 82.7%, and in R.I.A. test 95.8% 2. Using the result of R.I.A. test as the standard, sensitivity of P.H.A. test with domestic product P.H.A. kit was 84.8% and specificity was 100.0% 3. Using the result of R.I.A. test as standard, sensitivity of P.H.A. test with foreign P.H.A. kit was 86.4% and specificity was 100.0%. 4. The concordance rate of P.H.A. test with domestic product and foreign product kit was 98.5%. On the result of this study, there was no significant difference in the validity between the domestic product P.H.A. kit 'Hepa-S' and the foreign P.H.A. kit $'Hebsgencell^{TM}'$. So that it is recommendable to use domestic product P.H.A. kit instead of foreign product P.H.A. kit.