• 대한안전경영과학회지
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• 제26권3호
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• pp.51-57
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• 2024

The purpose of this study is to compare and analyze the impact range of explosion damage due to gas leaks at LPG filling stations, focusing on propane and butane, which are components of vehicle LPG. The scenarios were designed based on the explosion incident at an LPG filling station in Gangwon-do, where an actual gas leak accident occurred, resulting in Scenario I and Scenario II. The ALOHA program, developed by the U.S. National Oceanic and Atmospheric Administration (NOAA), was used as the tool to analyze the impact range of the explosion damage for both substances. The results of the study indicated that, under identical conditions, propane had a wider impact range of damage than butane. This is presumed to be due to the greater explosion energy of propane, attributable to its physicochemical properties. Therefore, when preparing for LPG leak accidents, measures for propane need to be prioritized. As safety measures for propane, two suggestions were made to minimize human casualties. First, from a preventive perspective, it is suggested to educate workers about propane. Second, from the perspective of response measures and damage minimization, it is suggested to thoroughly prepare emergency evacuation and rescue plans, evacuation routes, designated shelters, and emergency response teams. This study compares and analyzes the impact range of radiative heat damage based on LPG components. However, hazardous accidents are critically influenced by the type of leaking substance, the form of the leak, and meteorological factors affecting the diffusion pattern of the substance. Therefore, for future research, it is proposed to model various leakage scenarios for the same substance to conduct a comprehensive risk assessment.

• 대한통합의학회지
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• 제11권4호
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• pp.1-15
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• 2023

Purpose : This study investigates the effectiveness of digital therapy for stroke patients in Korea. Methods : A comprehensive database search was performed using KCI, Science on, e-article, RISS, KISS and Korea OpenMed databases for randomized controlled trials (RCTs) that studied the effects of digital therapy on patients who had a stroke. This study includes RCTs published from January 2000 to July 15, 2022, which fulfilled the inclusion and exclusion criteria. A total 697 studies were screened and 30 studies were included in the final analysis. Methodological quality was assessed with the Cochrane's RoB (risk of bias) tool. Meta-analysis was performed using CMA 4.0 software. Results : A total of 56 effect sizes were calculated from the 30 selected studies. As a result of the analysis, the overall effect size of digital therapy was .59 (95 % CI=.43-.74). When classified according to type of intervention, VR (virtual reality) (g=.58, 95 % CI=.40-.75), and CACR (computer assisted cognitive rehabilitation) (g=.62, 95 % CI=.30-.95) were statistically significant. VR showed medium to large effect sizes in cognitive function (g=.78, 95 % CI=.20-1.37), psychosocial function (g=.63, 95 % CI=.20-1.07), and physical function (g=.61, 95 % CI=.38-.83). In the CACR, there was a large effect size in cognitive function (g=.84, 95 % CI=.52-1.15), but there was no significant difference in psychosocial function. Also, there was no significant difference between the two interventions in activities of daily living and no significant difference in the effect size of both interventions according to the intervention session. Furthermore, medium to large effect sizes were found for subacute and chronic stroke patients according to the duration of disease. Conclusion : This study presents evidence that digital therapy has a positive effect on various functions of stroke patients in Korea. The researchers expect to actively accept the new paradigm of digital therapy and continue to apply digital therapy in clinical practice.

• Mass Spectrometry Letters
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• 제14권3호
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• pp.91-103
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• 2023

As one of the most common mood disorders, numerous studies have shown depression is the main risk factor for non-suicidal self-harm. The pathogenesis of depression is complex, and a comprehensive and rapid measurement of monoamine neurotransmitters and their metabolites will be very helpful in understanding the pathogenesis of depression. Therefore, a rapid and sensitive underivatized liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous monitoring of the levels of ten neurotransmitters and their metabolites in rat serum and limbic system and successfully applied to quantify the changes of neurotransmitter levels in chronic unpredictable mild stress-induced rats. The analytes studied were mainly involved in tyrosine metabolism, tryptophan metabolism, and glutamate cycling pathways, which are important in the pathogenesis of depression. It had been verified the method was sensitive and effective, with satisfactory linearity, and met the requirements of biological sample determination. Levels of neurotransmitters in rat serum, hippocampus, amygdala, prefrontal cortex, striatum, and hypothalamus were determined via the method. The results showed serotonin, dopamine, norepinephrine, and their metabolites were decreased, glutamine was increased, and glutamate was disturbed in chronic unpredictable mild stress-induced depression rats. This method provides a new approach to studying the pathogenesis of depression and other neurological disorders.

• 한국ITS학회 논문지
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• 제23권1호
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• pp.42-60
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• 2024

본 연구는 자율주행 차량이 혼재된 교통류의 안전성 평가에 적합한 안전성 지표를 선정하여 차량 추종 조합별 안전성을 분석하였다. 고속도로 엇갈림구간은 기본구간에 비해 차로 변경이 빈번하여 상충 빈도가 높은 구간으로, 일반 차량과 자율주행 차량의 주행행태 차이로 인한 위험이 증가할 것으로 예상하여 고속도로 엇갈림구간을 분석구간으로 설정하였다. 미시적 교통 시뮬레이션인 VISSIM을 활용하여 분석을 수행하였으며, 혼합 교통류의 환경은 본선-연결로 형태의 엇갈림구간을 300, 600m의 길이로 구분하고, IDM을 활용하여 자율주행 차량의 주행행태를 구현하였다. 혼합 교통류 평가에 적합한 안전성 지표는 운전자가 체감하는 위험도와 유사하게 위험 수준을 나타내는 것을 기준으로 4개의 지표를 선정하였다. 선정된 4개 지표의 위험 기준을 넘는 차량 추종 궤적을 대상으로 안전성을 분석한 결과, 자율주행 차량이 자율주행 차량을 추종하는 상황이 가장 안전한 추종 쌍이며, 인간 운전자 차량이 자율주행 차량을 추종할 경우가 가장 위험한 추종 쌍인 것으로 나타났다.

• 성인간호학회지
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• 제28권3호
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• pp.288-301
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• 2016

Purpose: The purpose of this study was to identify association between maternal depression and multiple contextual factors in 1,519 mothers in Korea who participated in the 2009 Panel Study of Korean Children (PSKC). Methods: The second wave data which was a comprehensive longitudinal data set with a nationally representative birth cohort was analyzed using SAS 9.3 software. Kessler depression scale was used for this study. Results: Of the mothers, 23.0% reported being mild to moderate depression and 4.5% of the mothers reported severe depression. The factors influencing maternal depression include; mother's self-efficacy, mother's marital conflict, mother's social support, infant's and toddler's emotionality, mother's smoking and infant's feeding & eating of daily routine. These variables explained 39.5% of maternal depression. Conclusion: The results of this study suggest that the identified factors for maternal depression should be included in an intervention program to reduce the risk of depression.

• Journal of Chest Surgery
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• 제18권3호
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• pp.517-528
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• 1985

Pulmonary function studies today are generally accepted as an integral part of the evaluation of poor-risk patients who are to have pulmonary surgery. The effect of various pulmonary surgery on lung function was investigated in 54 patients in whom comprehensive lung function test were performed before and between 2 months and 14 months after operation at the Department of Thoracic Surgery, Seoul National University Hospital. According to the result of analysis, the effect of pulmonary resection on forced flow rate was keeping with the change of lung volume, and the preoperative level of ventilatory function plays a major role in determining postoperative loss of functioning lung. Although all measures of expiratory flow [FVC, FEV1, FEFO.2-1.2, MEF50, FEF25-75] have the same percentage of reproducibility, but FEV1 shows most sensitive, reliable linear correlation with the functioning pulmonary tissue loss than other parameters. The linear regression lines derived from the correlation between preoperative [X] and postoperative [Y] FEV1 on various surgical procedures were as follows: 1. Y = 0.57X 0.03. in pneumonectomy group of lung cancer[r=0.84]. 2. Y = 0.56X + 0.33. in lobectomy group of lung cancer[r=0.79]. 3. Y = 0.69X + 0.25. in lobectomy group of pulmonary infection[r=0.91].

• Structural Engineering and Mechanics
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• 제59권4호
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• pp.653-669
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• 2016

Recent earthquakes worldwide show that a significant portion of the earthquake shaking happens in the vertical direction. This phenomenon has raised significant interests to consider the vertical ground motion during the seismic design and assessment of the structures. Strong vertical ground motions can alter the axial forces in the columns, which might affect the shear capacity of reinforced concrete (RC) members. This is particularly important for non-ductile RC frames, which are very vulnerable to earthquake-induced collapse. This paper presents the detailed nonlinear dynamic analysis to quantify the collapse risk of non-ductile RC frame structures with varying heights. An array of non-ductile RC frame architype buildings located in Los Angeles, California were designed according to the 1967 uniform building code. The seismic responses of the architype buildings subjected to concurrent horizontal and vertical ground motions were analyzed. A comprehensive array of ground motions was selected from the PEER NGA-WEST2 and Iran Strong Motions Network database. Detailed nonlinear dynamic analyses were performed to quantify the collapse fragility curves and collapse margin ratios (CMRs) of the architype buildings. The results show that the vertical ground motions have significant impact on both the local and global responses of non-ductile RC moment frames. Hence, it is crucial to include the combined vertical and horizontal shaking during the seismic design and assessment of non-ductile RC moment frames.

• Child Health Nursing Research
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• 제12권1호
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• pp.5-14
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• 2006

Purpose: The purpose of study was to describe and evaluate the educational status regarding clinical practicum for child health nursing to facilitate student's clinical compliance for the bachelor's degree in Korea. Methods: The study was a descriptive study and included data from 40 institutions among the 53 university nursing programs in Korea(75.5% response rate). Data were collected using mailed semi structured questionnaires and content analysis was done. Results: Findings show that most institutions have common learning objectives for the clinical practicum; neonatal care, high risk infant care, hospitalized child care, and advanced nursing practice. The mode for theoretical credits in child health nursing was 5 to 6 and 3 to 4 credits for clinical practice. The practice settings were prepared to provide diverse experiences, including childcare centers, and community centers with various learning activities. Evaluation for learning outcomes included faculty and instructors. It was pointed out that updating evaluation based on student and faculty feedback is important for a comprehensive practicum evaluation. Conclusions: Findings suggest that there is a -need for a generalized curriculum for clinical practicum and for the expanding role of advanced nursing practice-, a need for diverse clinical settings for practice, and effective guidance and learning activities. It is significantly noted that the attitude and teaching methodologies of clinical instructor's are highly important to effective clinical learning outcomes.

• Journal of Preventive Medicine and Public Health
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• 제44권4호
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• pp.157-166
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• 2011

Objectives: This study was conducted to show the intraocular pressure (IOP) distribution and the factors affecting IOP in subjects with type 2 diabetes mellitus (DM) in India. Methods: We measured the anthropometric and biochemical parameters for confirmed type 2 DM patients. A comprehensive ocular examination was performed for 1377 subjects aged > 40 years and residing in Chennai. Results: A significant difference in IOP (mean ${\pm}$ standard deviation) was found between men and women ($14.6{\pm}2.9$ and $15.0{\pm}2.8$ mmHg, p = 0.005). A significantly elevated IOP was observed among smokers, subjects with systemic hypertension and women with clinically significant macular edema (CSME). After a univariate analysis, factors associated significantly with higher IOP were elevated systolic blood pressure, elevated resting pulse rate and thicker central corneal thickness (CCT). In women, elevated glycosylated hemoglobin was associated with a higher IOP. After adjusting for all variables, the elevated resting pulse rate and CCT were found to be associated with a higher IOP. Conclusions: Systemic hypertension, smoking, pulse rate and CCT were associated with elevated intraocular pressure in type 2 DM. Women with type 2 DM, especially those with CSME, were more prone to have an elevated IOP.

• 보건행정학회지
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• 제24권3호
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• pp.271-282
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• 2014

Background: Although the mortality rate in cancers has been decreased recently, it is still one of the leading causes of death in most of the countries. This study analyzed the relationship between surgery volume and in hospital mortality of cancer patients. The purpose of this study is to investigate the relationship in Korean healthcare environment and to provide information for the policy development in reducing cancer mortality. Methods: The study sample was the 20,517 cancer patients who underwent surgery and discharged during a month period between 2008-2011. The data were collected in Patient Survey by Korean Institute of Social Affairs. Logistic regression was used to analyse a comprehensive analytic model that includes a binary dependent variable indicating death discharge and independent variables such as surgery volume, organizational characteristics of hospitals, socio-economical characteristics of the patients, and severity of disease indicators. Results: In chi-square test, as the surgery volume increases, the in-hospitals mortality showed a downward trends. In regression analysis, the relationship between surgery volume and mortality showed significant negative associations in all types of cancer except for pancreatic cancer. Conclusion: In the absence of other information patients undergoing cancer surgery can reduce their risk of operative death by selecting a high-volume hospital. Therefore, policies to enhance centralization of cancer surgery services should be considered.