• 대한의용생체공학회:의공학회지
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• 제36권6호
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• pp.291-295
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• 2015

Various types of implantable drug delivery devices have attracted significant attention for several decades to improve drug bioavailability and reduce side effects, thus enhancing therapeutic efficacy and patients' compliance. However, when implanted into the body, the devices may be influenced by the changes in physiological condition, such as temperature, pH or ionic concentration. Thus, the drug release rates could be also altered concurrently. Therefore, in this work, we employed an implantable ALZET$^{(R)}$ Osmotic Pump, which has been widely used to locally deliver various therapeutic agents and examined the effect of pH, temperature and ionic concentration on its drug release rate. For this, we performed in vitro cell tests to simulate the condition of local tissues influenced by the altered drug release rates, where we used diclofenac sodium as a model drug.

• 한국의료질향상학회지
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• 제3권1호
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• pp.126-143
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• 1996

Background : Little work has been carried out regarding quality assessment research in a primary care setting, comparing with that of hospitals. This study aims to evaluate the process of diagnosis and management of hypertension by public health doctors on the basis of pre-established clinical guideline, and to identify several modifying factors associated with them. Methods : Hypertension was selected as the target disease, because it is a chronic disease which is of great public health importance. Self-administered questionnaires were mailed to public health doctors practicing at health centers and health subcenters across the nation. The response rate was 20.9%. The questionnaire included the diagnosis and management process such as measuring blood pressure, history taking, physical examinations, and treatment approches and potentially modifying factors such as level of training, duration of practice as a public health doctor, and education on management of hypertension. Results : Public health doctors pay little attention in measuring BP, hypertension related history taking, performing physical examination and laboratory examination. But they devoted much effort in diagnosing hypertension exactly and giving nonpharmacological treatment. Among various antihypertensive drugs, calcium-channel blockers were the most preferred agent(50.9%). Level of training, duration of practice ad a public health doctor, and education on management of hypertension made no difference on quality of care(p>0.05). Conclusion : These public health doctors showed poor compliance with the pre-established clinical guidelines, which leaves much to be desired in diagnosing and managing hypertensive patients by public health doctors. This study might be able to contribute to develop some strategies, such as educational programs, which would be able to improve the process of care in hypertensives.

• 대한두개안면성형외과학회지
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• 제15권2호
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• pp.47-52
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• 2014

Background: Management of positional plagiocephaly by wearing a cranial molding helmet has become a matter of growing medical interest. Some research studies reported that starting helmet therapy early (age 5 to 6 months) is important and leads to a significantly better outcome in a shorter treatment time. The aim of the present study was to evaluate the effectiveness of cranial remodeling treatment with wearing helmet for older infants (${\geq}18$ months). Methods: We conducted a retrospective study of 27 infants with positional plagiocephaly without synostosis, who were started from 2008 to 2012. Every child underwent a computerized tomography (CT) before starting helmet therapy to exclude synostosis of the cranial sutures and had CT performed once again after satisfactory completion of therapy. Anthropometric measurements were taken on using spreading calipers in every child. The treatment effect was compared using cranial vault asymmetry (CVA) and the cranial vault asymmetry index (CVAI), which were obtained from diagonal measurements before and after therapy. Results: The discrepancy of CVA and CVAI of all the patients significantly decreased after cranial molding helmet treatment in older infants (${\geq}18$ months) 7.6 mm from 15.6 mm to 8 mm and 4.51% from 9.42% to 4.91%. Six patients had confirmed successful outcome, and all subjects were good compliance patients. The treatment lasted an average of 16.4 months, was well tolerated, and had no complication. Additionally, the rate of the successful treatment (final CVA ${\leq}5mm$) significantly decreased when the wearing time per was shorter. Conclusion: This study showed that treatment by cranial remodeling orthosis was effective if the patient could wear the helmet longer and treatment duration was somewhat longer than in younger patients, well tolerated in older infants and had no morbidity. This therapeutic option is available and indicated in these older infants before other cranial remodeling surgery.

• Tuberculosis and Respiratory Diseases
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• 제69권2호
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• pp.75-80
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• 2010

The year of 2009~2010 brought a number of concepts and new ideas were evaluated with promising results. However, some studies that challenged many beliefs. In acute respiratory distress syndrome (ARDS), recent clinical studies took into consideration of pathophysiologic changes of respiratory system compliance. Meta-analysis of positive end-expiratory pressure trials showed survival benefit of high positive end-expiratory pressure in ARDS. Until now, prone positioning did not show survival benefit in patients with ARDS. Extracorporeal membrane oxygenation (ECMO) based management improved survival in patients with severe ARDS. ECMO can be a management option in severe ARDS. Sedation is a standard practice in critically ill patients needing mechanical ventilation. However, Danish group reported less sedation of critically ill patients receiving mechanical ventilation was associated with an increase in days without ventilation. Although this single center study has some limitations, the overall results are promising. Use of maximal sterile barrier precautions (mask, sterile gown, sterile gloves, and large sterile drapes) with chlorhexidine-impregnated dressing reduced central venous catheter related infection. Selective oropharyngeal decontamination (application of topical antibiotics in the oropharynx) reduced the mortality rate of an intensive care unit (ICU) population. Normoglycemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE-SUGAR) trial reported intensive glucose control increased mortality among adults in the ICU. Some of the results of above papers are promising. However, some ideas may need for more frequent individual assessment and increase the workload of ICU staffs. Before implementation of new practice in ICU, we should take into consideration of individual hospital situation including human and material resources.

• 콘크리트학회논문집
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• 제17권2호
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• pp.255-261
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• 2005

본 연구에서는 매년 많은 양의 석탄회 발생으로 인한 환경오염을 줄이고 천연자원의 채취와 고갈로 인한 문제를 극복하기 위해, 산업 폐기물의 건설재료로서의 재활용 가능성을 확보하기 위한 기초적인 연구자료를 제시하였다. 압축강도실험을 통하여 재료에 대한 탄성계수값을 측정하였으며, 3점 휨파괴시험으로부터는 파괴에너지, 초기노치비, 노치민감도등을 평가함으로써 파괴역학적 파라메타를 제안하였다. 실험 결과, 초기강도는 콘크리트에 비해 낮으나 장기강도에서는 비슷함을 볼 수 있었다 하지만 파괴강도가 증가함에 따라 취성적인 경향을 보이면서 파괴에너지값은 낮음을 알 수 있었다. 또한 하중-변위곡선과 하중-균열개구변위곡선의 형태는 모두 비슷한 형태를 띠고 있었으며, 재령이 증가할수록, 노치비는 작을수록 최대하중값이 커지면서 파괴시의 처짐은 감소함을 알 수 있다. 하지만 파괴강도가 커지면서 취성적인 경향으로 최대하중이후의 연화구간의 기울기가 급해짐을 볼 수 있었다. 따라서 연성의 확보에 대한 추가적인 보완연구가 진행되어진다면 충분히 건설재료로 사용 가능할 것으로 판단되어진다.

• Journal of electromagnetic engineering and science
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• 제16권2호
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• pp.87-99
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• 2016

This paper describes an implementation method and the results of numerical mobile phone models representing real phone models that have been released on the Korean market since 2002. The aim is to estimate the electromagnetic absorption in the human brain for case-control studies to investigate health risks related to mobile phone use. Specific absorption rate (SAR) compliance test reports about commercial phone models were collected and classified in terms of elements such as the external body shape, the antenna, and the frequency band. The design criteria of a numerical phone model representing each type of phone group are as follows. The outer dimensions of the phone body are equal to the average dimensions of all commercial models with the same shape. The distance and direction of the maximum SAR from the earpiece and the area above -3 dB of the maximum SAR are fitted to achieve the average obtained by measuring the SAR distributions of the corresponding commercial models in a flat phantom. Spatial peak 1-g SAR values in the cheek and tilt positions against the specific anthropomorphic mannequin phantom agree with average data on all of the same type of commercial models. Second criterion was applied to only a few types of models because not many commercial models were available. The results show that, with the exception of one model, the implemented numerical phone models meet criteria within 30%.

• 대한물리치료과학회지
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• 제9권4호
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• pp.63-72
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• 2002

Patient satisfaction is an important factor in evaluating the quality of care. Patient satisfaction may be used to evaluate provider services and facilities, and used to predict the patient returns to a facility. The patients d whether the patient returns to a facility or whether the patient recommends the facility to other people may be affected by a variety of factors of patient satisfaction. Low satisfaction may result in poor compliance with the potential of waste of resources and suboptimal clinical outcome. This study is to identify factors of patient satisfaction that will affect patients decision whether the patient returns or not. A self-administered questionnaire survey was conducted in Seoul, Chung-Joo and Bu-Cheon cities, Survey data was obtained from 743 patients who visited the physical therapy practice at university hospitals, general hospitals and clinics. Response rate was 94.4%. The instrument developed by Goldstein et al. (2000) was used and translated into Korean. Several items were added to the instrument. Patient's opinions of service in each domain measured using 5-point Likert-type scales that ranged from strongly disagree to strongly agree. A multiple-regression analytic approach was used to predict overall satisfaction of physical therapy. Age, kindness, scheduling, convenience of parking, privacy, and waiting time predicted the overall satisfaction of physical therapy. The older patients had higher level of satisfaction with physical therapy compared with the younger patients. Patient satisfaction were more affected by access (scheduling and waiting time), administrative technical management (convenience of parking), and interpersonal management (kindness of physical therapists and other staffs) than clinical technical management (physical therapists' skills).

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.80-85
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• 1996

The various function of the cardiovascular system(CVS) and the dynamic characteristics on each part of human body can be acquired in the electric analog circuit model. According to the performed outcome by other researchers, viscos resistance, flow inertia, and vascular compliance in the CVS are analogous to resister, inductor, and capacitor in electric circuit, so the CVS models were represented by the electric circuit models. these approaches were to propose the suitable models interest part of body and to simulate the various characteristics on the CVS. In this paper, the electric circuit model considering the characteristics of morphologic structure is represented, the parameter values of model is sotted up, and the dynamic characteristics of the the CVS is simulated using VisSim, one of the simulation tools. The observed simulation results are similar to the cardiovascular functions of nomal adults who have no heart failure. Besides, the simulation is operated to observe the pathophysiological abnomal symptoms(for example, bleeding within a certain period). The controller by baroreceptor, which is one of controllers to control the CVS, is appended in the model. and the dynamic response characteristics and the procedure to return normal state is observed in simulation when the bleeding last within a certain period.

• Safety and Health at Work
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• 제9권1호
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• pp.95-100
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• 2018

Background: Respiratory protection equipment (RPE) is the last resort to control exposure to workplace air pollutants. A comprehensive respiratory protection program (RPP) ensures that RPE is selected, used, and cared properly. Therefore, RPP must be well integrated into the occupational health and safety requirements. In this study, we evaluated the implementation of RPP in Iranian petrochemical industries to identify the required solutions to improve the current status of respiratory protection. Methods: This cross-sectional study was conducted among 24 petrochemical industries in Iran. The survey instrument was a checklist extracted from the Occupational Safety and Health Administration respiratory protection standard. An index, Respiratory Protection Program Index (RPPI), was developed and weighted by analytic hierarchy process to determine the compliance rate (CR) of provided respiratory protection measures with the RPP standard. Data analysis was performed using Excel 2010. Results: The most important element of RPP, according to experts, was respiratory hazard evaluation. The average value of RPPI in the petrochemical plants was $49{\pm}15%$. The highest and lowest of CR among RPP elements were RPE selection and medical evaluation, respectively. Conclusion: None of studied petrochemical industries implemented RPP completely. This can lead to employees' overexposure to hazardous workplace air contaminants. Increasing awareness of employees and employers through training is suggested by this study to improve such conditions.

• 한국유기농업학회지
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• 제25권1호
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• pp.101-112
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• 2017

본 연구는 안전한 축산물의 생산에 기반이 되는 농가 HACCP 제도 도입에 있어서 일부 문제로 인하여 발생되고 있는 HACCP 인증(재인증) 부적합농가 수의 지속적인 증가에 대한 문제점을 개선하기 위한 방안으로 최근 3년간 HACCP 심사 결과에 따른 지적비율을 축종별로 분석하고 상위 10% 이상 지속적으로 지적되고 있는 평가항목을 도출하여 이를 개선할 수 있는 방안을 마련하고자 실시하였다. 총 15개 HACCP 관리 분야 평가항목 중 지적비율이 높은 평가항목으로는 소, 돼지 농가에서 4번(가축사육 공정도 및 농장평면도), 10번(중요관리점 모니터링), 12번(HACCP 검증), 14번(HACCP 교육) 그리고 닭농가에서는 10번(중요관리점 모니터링), 12번(HACCP 검증), 14번(HACCP 교육)으로 매우 유사한 경향을 나타내었다. 이러한 문제점을 개선하기 위해서는 농가 HACCP 평가기준의 대폭 축소 및 단순화, 연 1회 의무 교육 시 해당 분야 집중 교육과 위해요소중점관리기준, 모니터링, 검증 등과 같은 어려운 HACCP 용어를 각각 안전관리기준, 감시, 확인 등으로 이해하기 쉽게 풀어서 사용하여 국내 축산농가의 현실에 눈높이를 맞추어 개정되어야 많은 축산농가에서 가축사육단계 HACCP 제도를 부담 없이 안정적이고 지속적으로 운용할 수 있을 것으로 판단된다.