• The Journal of Korean Medical History
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• v.30 no.1
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• pp.23-31
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• 2017

Euibangyoochui (醫方類聚), the largest medical book in Korea, has medical and historical significance in that it had classified almost all East Asian medical accomplishments before Joseon Dynasty (1392-1910). Focusing on these values, this research investigates Yi'an (醫案), an East Asian tradition of describing clinical encounters and the therapies employed, in Euibangyoochui. By this investigation, this study expected to not only establish how the genre of Yi'an is employed for what purpose in Euibangyoochui, but also to shed a light on the appearance of Yi'an before Joseon Dynasty. At first, this study extracted Yi'an from Euibangyoochui (醫方類聚), as Yi'an does not have a standardized format. In total, the number of extracted Yi'ans is 1,025 with handwork results. Extracted Yi'ans are analyzed statically, in order to find dispersion of Yi'ans for each chapter and its references. Overall, there are 73 chapters of Euibangyoochui, which has a total of 93 chapters, containing Yi'an, while the chapter on gynecology contains the highest number of Yi'ans, 86. Judged from these result, the genre of Yi'an was used diversely and frequently, indicating various messages in Euibangyoochui. To categorize the usage and purpose of writing of Yi'ans in Euibangyoochui, this study considers some examples of Yi'ans and concludes that 3 types of Yi'ans are employed in Euibangyoochui in order to deliver the adequate medical message. One is result-centered Yi'an delivering a broader medical lesson, such as a taboo in treatment or a doctrine in medicine. The second is the concise-styled Yi'an presenting a short effective medical method. The third is multiple-information Yi'an that describes complex information of patients and medical theories, transmitting diverse lessons. Yi'ans in Euibangyoochui refer to 58 medical books. Books written by JangJaHwa (張子和; 1156-1228) are the most cited books, offering almost a quarter of total amount of Yi'ans in Euibangyoochui. This study is meaningful in that it provides basic information, such as numbers, applications, purpose of writing and references of Yi'an in Euibangyoochui. Moreover considering the historic values of Euibangyoochui, this information reflects, on the other hands, overall figures of Yi'an written before publication of Euibangyoochui.

• Applied Microscopy
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• v.28 no.2
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• pp.139-158
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• 1998

The development of the superior cervical ganglion was studied by electron microscopic method in human fetuses ranging from 40 mm to 260 mm of crown-rump length (10 to 30 weeks of gestational age). At 40 mm fetus, the superior cervical ganglion was composed of clusters of undifferentiated cell, primitive neuroblast, primitive supporting cell, and unmyelinated fibers. At 70mm fetus, the neuroblasts and their processes were ensheated by the bodies or processes of satellite cells. The cytoplasm of the neuroblast contained rough endoplasmic reticulum, mitochondria, Golgi complex, Nissl bodies and dense-cored vesicles. As the neuroblasts grew and differentiated dense-cored vesicles moved away from perikaryal cytoplasm into developing processes. Synaptic contacts between the cholinergic axon and dendrites of postganglionic neuron and a few axosomatic synapses were first observed at 70 mm fetus. At 90 mm fetus the superior cervical ganglion consisted of neuroblasts, satellite cells, granule-containing cells, and unmyelinated nerve fibers. The ganglion cells increased somewhat in numbers and size by 150 mm fetus. Further differentiation resulted in the formation of young ganglion cells, whose cytoplasm was densely filled with cell organelles. During next prenatal stage up to 260 mm fetus, the cytoplasm of the ganglion cells contained except for large pigment granules, all intracytoplasmic structures which were also found in mature superior cervical ganglion. A great number of synaptic contact zones between the cholinergic preganglionic axon and the dendrites of the postganglionic neuron were observed and a few axosomatic synapses were also observed. Two morphological types of the granule-containing cells in the superior cervical ganglion were first identified at 90 mm fetus. Type I granule-containing cell occurred in solitary, whereas type II tended to appeared in clusters near the blood capillaries. Synaptic contacts were first found on the solitary granule-containing cell at 150 mm fetus. Synaptic contacts between the soma of type I granule-containing cells and preganglionic axon termials were observed. In addition, synaptic junctions between the processes of the granule- containing cells and dendrites of postganglionic neuron were also observed from 150 mm fetus onward. In conclusion, superior cervical ganglion cells and granule-containing cells arise from a common undifferentiated cell precursor of neural crest . The granule-containg cells exhibit a local modulatory feedback system in the superior cervical ganglion and nay serve as interneurons between the preganglionic and postganglionic cells.

• Korean Journal of Microbiology
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• v.41 no.4
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• pp.239-245
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• 2005

Transformation-Associated Recombination (TAR) cloning technique allows selective isolation of chromosomal regions and genes from complex genomes. The procedure requires knowledge of relatively small genomic sequences that reside adjacent to the chromosomal region of interest. This technique involves homologous recombination during yeast spheroplast transformation between genomic DNA and a TAR vector that has 5' and 3' gene targeting sequences. In this study, we examined the effect of non-homologous spacing sequence in target hooks on homologous recombination using a plasmid model system. The efficiency of homologous recombination between the modified his3-TRP1-his3 fragments and HlS3 gene on plasmid were analyzed by the characterization of $Ura^+$ transformants. The numbers of $Ura^+$ transformant showed same level when seven different modified his3-TRP1-his3 fragments were used. But the percentage of positive recombinants. $Trp^+His^-$, dramatically decreased when used the modified his3-TRP1-his3 fragments contained incorrect spacing of nonhomologous region. As a result, we suggest that incorrect spacing inhibits the homologous recombination between target hook and substrate DNA. Therefore, we should consider the correct spacing in target hook when the target hook are used for cloning of orthologue gene.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.31 no.4
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• pp.471-476
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• 1998

Microbiological spoilage of marine fish is complex process occurring by bacteria, yeasts and molds. There have been rare study for saprophytic yeasts although having enormous numbers of bacteriological studies on the spoilage of marine fish. The 14 genera of yeasts isolated from mackerel (Scomber japonicus) with high frequency of occurrence were Candida sp., Rhodotorula sp., Torulopsis sp., Cryptotoccus sp. and Tricosporon sp. Among these ones Candida lipolytica was identified as the strongest proteolytic yeast, then named Candida lipolytica FM5 (C. lipolytica FM5). C. lipolytica FM5 showed optimum growth at $25^{\circ}C$, pH 7.0 and could grow at $5^{\circ}C$ and in medium containing $10\%$ sodium chloride, To evaluate the saprophytic activity of the selected strain, C, lipolytica FM5 and Pseudomonas fluorescens ATCC 17571 which is one of representative spoilage bacteria were individually inoculated into the sterilized fish muscle homogenates, and then pH changes and volatile basic nitrogen (VBN) values were checked during the storage at various temperatures. According to the experimental results, the productions of VBN by C. lipolytica FM5 in the fish muscle homogenates were 50 mg-N/100 g at $5^{\circ}C$, 152 mg-N/100 g at $15^{\circ}C$ and 379 mg-N/100 g at $25^{\circ}C$ for 1 week storage, respectively. Above results were nearly same as in case of Ps. fluorescens ATCC 17571 inoculation. It suggest that sapyophytic yeasts also have important role in spoilage of marine fish.

• Journal of the Korean Society for Railway
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• v.18 no.6
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• pp.630-638
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• 2015

The total number of passengers on the KTX since its construction in 2004 surpassed 500 million in October, 2015. The operation of KTX made it possible to reach anywhere in a country in half a day, which subsequently altered people's lifestyle. As the KTX has become an important mode of transportation, there is a growing interest in the optimal size and location of its stations. Currently, the stations are constructed through public-private partnerships since a sufficient amount of budget is hard to secure only from the public sector; however, because railway stations are traditionally aimed at promoting public interests, an emphasis on the profitability of the private sector could compromise public interests. At this juncture, this study separately computes the number of users based on each of the two primary functions of the stations-as a railway station and as a sales facility-and estimates the numbers of people according to various transportation modes that are taken to access the stations. This estimation is applied to the case of Dongdaegu Station, which will open in 2016. Such an application helps to predict and respond to possible congestion as brought about by the expansion of the sales facility.

• Journal of Korea Water Resources Association
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• v.52 no.8
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• pp.531-543
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• 2019

Constructing a reliable runoff model and reducing model runtime are important in research of real-time urban flood forecasting to reduce the repetitive flood damage. Sewer networks in the major urban basin such as Seoul are vast and complex so that it is not suitable for real-time urban flood forecasting. Therefore, the rainfall-runoff model should be simplified. However, the runoff results due to the simplification of sewer networks can vary depending on the subjectivity and simplification method of the researcher and there is a significant difference especially in 2-D inundation analysis. In this study, the sewer networks in various urban basins with different numbers and distributions of sewer networks were simplified to certain criteria. The accuracy of the simplification model according to the sewer network scale is evaluated by 2-D inundation analysis. The runoff models of Gwanak, Sillim, and Dorimcheon, frequently inundated basins were simplified based on four simplification ranges due to the cumulative drainage area set as a criterion for calculating the simplification range. This study will be expected that the inundation result of simplification models estimated through the analysis can contribute to the construction of a reasonable and accurate runoff model suitable for real-time flood forecasting.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.36-46
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• 2019

The number of hosts connected to the Internet has increased dramatically, introducing the Domain Name System(DNS) in 1984. DNS is now an important key point for all users of the Internet by allowing them to use a convenient character address without memorizing a series of numbers of complex IP address. However, relative to the importance of DNS, there still exist many problems such as the authorization allocation issue, the disputes over public registration, security vulnerability such as DNS cache poisoning, DNS spoofing, man-in-the-middle attack, DNS amplification attack, and the need for many domain names in the age of hyper-connected networks. In this paper, to effectively improve these problems of existing DNS, we proposed a method of implementing DNS using distributed ledger technology, blockchain, and implemented using a Ethereum-based platform. In addition, the qualitative analysis performance comparative evaluation of the existing domain name registration and domain name server was conducted, and conducted security assessments on the proposed system to improve security problem of existing DNS. In conclusion, it was shown that DNS services could be provided high security and high efficiently using blockchain.

• Journal of Korean Society of Disaster and Security
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• v.14 no.1
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• pp.1-8
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• 2021

A corrugated pipe is widely used in firefighting equipment and sprinkler pipes because of its elasticity, which is less damaged by deformation and convenient facilities. However, the corrugated shape of the wall results in complex internal turbulent flow, and it is difficult to predict the pressure drop, which is an important design factor for pipe flow. The pressure drop in the corrugated tube is a function of the shape factors of the pipe wall, such as groove height, length, and pitch. Existing studies have only shown a study of pressure drop due to length changes in the case of D-shaped tubes with less than 5 pitch (P) and height (K) of the rectangular grooves in the tube. In this work, we conduct a numerical study of pressure drop for P/Ks with length and height changes of 2.8, 3.5 and 4.67 with Re Numbers of 55,000, 70,000 and 85,000. The pressure drop in the corrugated tube was interpreted to decrease with smaller P/K. We show that the pressure drop is affected by the change in the groove aspect ratio, and the increase in the height of the groove increases the recirculation area, and the larger the Reynolds number, the greater the pressure drop.

• Journal of the Korean Association of Geographic Information Studies
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• v.26 no.3
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• pp.12-36
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• 2023

Graph databases, which store different types of data and their relationships modeled as a graph, can be effective in managing and analyzing real estate spatial data linked by complex relationships. However, they are not widely used due to the limited spatial functionalities of graph databases. In this study, we propose a uniform grid-based real estate spatial data management approach using a graph database to respond to various real estate-related spatial questions. By analyzing the real estate community to identify relevant data and utilizing national point numbers as unit grids, we construct a graph schema that linking diverse real estate data, and create a test database. After building a test database, we tested basic topological relationships and spatial functions using the Jackpine benchmark, and further conducted query tests based on various scenarios to verify the appropriateness of the proposed method. The results show that the proposed method successfully executed 25 out of 29 spatial topological relationships and spatial functions, and achieved about 97% accuracy for the 25 functions and 15 scenarios. The significance of this study lies in proposing an efficient data integration method that can respond to real estate-related spatial questions, considering the limited spatial operation capabilities of graph databases. However, there are limitations such as the creation of incorrect spatial topological relationships due to the use of grid-based indexes and inefficiency of queries due to list comparisons, which need to be improved in follow-up studies.

• KIPS Transactions on Computer and Communication Systems
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• v.12 no.3
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• pp.111-118
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• 2023

Cyber attacks are increasing worldwide, and attacks on personal privacy such as CCTV and IP camera hacking are also increasing. If you search for IP camera hacking methods in spaces such as YouTube, SNS, and the dark web, you can easily get data and hacking programs are also on sale. If you use an IP camera that has vulnerabilities used by hacking programs, you easily get hacked even if you change your password regularly or use a complex password including special characters, uppercase and lowercase letters, and numbers. Although news and media have raised concerns about the security of IP cameras and suggested measures to prevent damage, hacking incidents continue to occur. In order to prevent such hacking damage, it is necessary to identify the cause of the hacking incident and take concrete measures. First, we analyzed weak account settings and web server vulnerabilities of IP cameras, which are the causes of IP camera hacking, and suggested solutions. In addition, as a specific countermeasure against hacking, it is proposed to add a function to receive a notification when an IP camera is connected and a function to save the connection history. If there is such a function, the fact of damage can be recognized immediately, and important data can be left in arresting criminals. Therefore, in this paper, we propose a method to increase the safety from hacking by using the connection notification function and logging function of the IP camera.